Prairie Vole OXTR-/- analysis
Author: Amanda Everitt
Began: 07/24/2023
Finished: 09/29/2024
Study Design
Main question of interest:
- Is there a molecular signature of pair bonding in the nucleus
accumbens?
- How does loss of OXTR in the nucleus accumbens effect gene
expression?
- Do these differ by sex?
colorize <- function(x, color) {
if (knitr::is_latex_output()) {
sprintf("\\textcolor{%s}{%s}", color, x)
} else if (knitr::is_html_output()) {
sprintf("<span style='color: %s;'>%s</span>", color,
x)
} else x
}Alignment + Pre-processing Methods
Adapter and low quality sequence trimming was performed with Trimmomatic v0.39 using parameters: ‘TruSeq3-PE.fa:2:30:10:2:keepBothReads LEADING:3 TRAILING:3 SLIDINGWINDOW:4:20 MINLEN:25’(Bolger et al., 2014). Trimmed RNA-Seq reads were aligned to a custom MicOch1.0 prairie vole genome, which incorporated a known missing gene V1A, using STAR v2.7.3a in gene annotation mode (Dobin et al., 2013). Alignment, RNA-Seq, and Insert Size quality control metrics were generated using Picard v 2.10.10 (http://broadinstitute.github.io/picard). Homologous genes between vole, mouse, and human references were identified using biomart v2.56.1. When multiple mouse or human genes mapped to the same vole gene, the homologous gene with the highest percent identity to vole was selected.Load Packages + Set env
suppressPackageStartupMessages({
library(plyr); library(dplyr);
library(DESeq2)
library(ggplot2)
library(tibble)
library(gridExtra)
library(purrr)
library(ggbiplot)
library(ggVennDiagram)
library(ComplexHeatmap)
library(kableExtra)
library(RUVSeq)
library(readxl)
library(fgsea)
#library(Seurat)
library(ggpubr)
library(STRINGdb)
library(clusterProfiler)
library(ggvenn)
library(igraph)
library(circlize)
library(ggh4x)
})
data_dir ="input_data/"
output_dir = "results/"
dir.create(output_dir, recursive = TRUE, showWarnings = FALSE)
dir.create(paste0(output_dir,"figures"), recursive = TRUE, showWarnings = FALSE)
par(mar=c(1,1,1,1), cex.axis=0.5, mfrow=c(1,1))
set.seed(1)
`%ni%` <- purrr::compose(`!`, `%in%`)#Load in metadata + make some helpful columns
metadata <- read.csv(paste0(data_dir,"KB_OXTR_metadata.csv"), header = T, stringsAsFactors = F)
metadata[metadata$species == "Prairie",]$species <- "WT"
metadata$FullID <- gsub("-bond","", paste0(metadata$SampleID, "_",metadata$species, "_",
metadata$Condition, "_", metadata$Sex))
rownames(metadata) <- metadata$FullID
metadata$SeqRun <- as.character(metadata$SeqRun)
metadata$Group <- paste0(ifelse(metadata$species == "WT", "wildtype","oxtr"), "_",
ifelse(metadata$Sex == "F", "female","male"), "_",
ifelse(metadata$Condition == "Post-bond", "post-bonding","pre-bonding"))
metadata$TechnicalRep <- as.character(metadata$TechnicalRep)
metadata$Condition <- as.factor(metadata$Condition)#Load counts
cts <- read.delim(paste0(data_dir,"trim_star2.7.3a_merged_counts.txt"), sep = "\t", row.names = 1)
cts <- cts[,order(match(colnames(cts), metadata$SampleID)),]
colnames(cts) <- metadata$FullID
original_cts <- cts#Load QC metrics
qc1 <- t(read.delim(paste0(data_dir,"trim_star2.7.3a_merged_counts.stats"), sep = "\t", row.names = 1))
qc2 <- read.delim(paste0(data_dir,"merged_qc.txt"), sep = "\t", row.names = 1)
qc3 <- merge(qc1, qc2, by="row.names", all=T)
qc_df <- merge(metadata[,c("SampleID", "FullID"), drop=F], qc3, by.x="SampleID", by.y="Row.names")
rownames(qc_df) <- qc_df$FullID
qc_df <- qc_df[, colnames(qc_df) %ni% c("SampleID", "FullID")]
qc_df <- qc_df[, as.numeric(which(apply(qc_df, 2, var) > 0 ))] #remove cols with no variance
qc_df <- as.data.frame(t(qc_df))
if(identical(colnames(qc_df), colnames(cts))){
qc_df["N_reads_mapped", ] <- colSums(cts)
}metadata[1:3,]## SampleID Experiment species Condition Sex Area lane RIN Result
## KB01_WT_Pre_F KB01 OXTR WT Pre-bond F NAc 1 7.6 Pass
## KB02_WT_Pre_F KB02 OXTR WT Pre-bond F NAc 1 8.1 Pass
## KB03_WT_Pre_F KB03 OXTR WT Pre-bond F NAc 1 8.9 Pass
## LibraryPrep Lane Yield Additional_througput TechnicalRep SeqRun
## KB01_WT_Pre_F Macrogen 0 6678 0 <NA> 1
## KB02_WT_Pre_F Macrogen 0 7353 0 26 1
## KB03_WT_Pre_F Macrogen 1 7701 1 <NA> 1
## FullID Group
## KB01_WT_Pre_F KB01_WT_Pre_F wildtype_female_pre-bonding
## KB02_WT_Pre_F KB02_WT_Pre_F wildtype_female_pre-bonding
## KB03_WT_Pre_F KB03_WT_Pre_F wildtype_female_pre-bondingcts[1:3,1:4]## KB01_WT_Pre_F KB02_WT_Pre_F KB03_WT_Pre_F KB04_WT_Pre_M
## ENSMOCG00000013030 0 0 0 0
## ENSMOCG00000004754 0 0 0 0
## ENSMOCG00000009923 0 0 0 0qc_df[1:3,1:4]## KB01_WT_Pre_F KB02_WT_Pre_F KB03_WT_Pre_F KB04_WT_Pre_M
## N_unmapped 469395 436706 635466 600854
## N_multimapping 197616 216878 222792 305858
## N_noFeature 3395153 3310686 3638380 5441607Building vole annotation
library("biomaRt")
voleGenes <- rownames(original_cts)
vole = useMart("ensembl", dataset = "mochrogaster_gene_ensembl")
#searchAttributes(mart = vole, pattern = "mochrogaster")
#need ensemblIDs for GO, need entrez IDs for GSEA
vole_homolgsPage = getBM(attributes = c("ensembl_gene_id",
"mmusculus_homolog_ensembl_gene",
"mmusculus_homolog_associated_gene_name",
"mmusculus_homolog_orthology_type",
"mmusculus_homolog_perc_id",
"hsapiens_homolog_ensembl_gene",
"hsapiens_homolog_associated_gene_name",
"hsapiens_homolog_orthology_type",
"hsapiens_homolog_perc_id"),
filters = "ensembl_gene_id",
values = voleGenes, mart=vole)
table(duplicated(vole_homolgsPage$ensembl_gene_id))
#FALSE TRUE
#23038 10229- Downstream we need each vole gene to have one ortholog which is a problem with the 1:many and many:many orthologs. I’m going to order information by the percent identity, but retain the rest of the info in other columns in case people would like to redo this later with different criteria.
dups <- vole_homolgsPage$ensembl_gene_id[duplicated(vole_homolgsPage$ensembl_gene_id)]
length(unique(dups))
#[1] 1245
#lets handle the mouse duplicated instances first.
pt1 <- vole_homolgsPage[vole_homolgsPage$ensembl_gene_id %in% dups, ] %>%
group_by(ensembl_gene_id) %>% #group by the vole unique ID
arrange(desc(mmusculus_homolog_perc_id)) %>% # for each group, arrange by the one we're "most confident" in
reframe(mmusculus_homolog_ensembl_genes = paste(mmusculus_homolog_ensembl_gene, collapse=", "),
mmusculus_homolog_associated_gene_names = paste(mmusculus_homolog_associated_gene_name, collapse=", "),
mmusculus_homolog_perc_ids = paste(mmusculus_homolog_perc_id, collapse=", "),
mmusculus_homolog_ensembl_gene = mmusculus_homolog_ensembl_gene[[1]],
mmusculus_homolog_associated_gene_name = mmusculus_homolog_associated_gene_name[[1]],
mmusculus_homolog_orthology_type = mmusculus_homolog_orthology_type[[1]],
mmusculus_homolog_perc_id = mmusculus_homolog_perc_id[[1]]) %>% #collapse info we want to keep.
unique()
length(pt1$ensembl_gene_id)
#[1] 1245
#lets handle the mouse duplicated instances first.
pt2 <- vole_homolgsPage[vole_homolgsPage$ensembl_gene_id %in% dups, ] %>%
group_by(ensembl_gene_id) %>% #group by the vole unique ID
arrange(desc(hsapiens_homolog_perc_id)) %>% # for each group, arrange by the one we're "most confident" in
reframe(hsapiens_homolog_ensembl_genes = paste(hsapiens_homolog_ensembl_gene, collapse=", "),
hsapiens_homolog_associated_gene_names = paste(hsapiens_homolog_associated_gene_name, collapse=", "),
hsapiens_homolog_perc_ids = paste(hsapiens_homolog_perc_id, collapse=", "),
hsapiens_homolog_ensembl_gene = hsapiens_homolog_ensembl_gene[[1]],
hsapiens_homolog_associated_gene_name = hsapiens_homolog_associated_gene_name[[1]],
hsapiens_homolog_orthology_type = hsapiens_homolog_orthology_type[[1]],
hsapiens_homolog_perc_id = hsapiens_homolog_perc_id[[1]]) %>% #collapse info we want to keep.
unique()
length(pt2$ensembl_gene_id)
#[1] 1245fixed = full_join(pt1,pt2)
vole_homolgsPage_fixed <- full_join(vole_homolgsPage[vole_homolgsPage$ensembl_gene_id %ni% dups, ], fixed)#now we have to add the entrezIDs for mouse and humans for the retained ensembl IDs.
vole_featurePage = getBM(attributes = c("ensembl_gene_id",
"gene_biotype", "entrezgene_id", "external_gene_name"),
filters = "ensembl_gene_id",
values = voleGenes,
mart=vole)
mouse = useMart("ensembl", dataset = "mmusculus_gene_ensembl")
mouse_featurePage = getBM(attributes = c("ensembl_gene_id", "entrezgene_id"),
filters = "ensembl_gene_id",
values = unique(vole_homolgsPage_fixed$mmusculus_homolog_ensembl_gene),
mart=mouse)
human = useMart("ensembl", dataset = "hsapiens_gene_ensembl")
human_featurePage = getBM(attributes = c("ensembl_gene_id", "entrezgene_id"),
filters = "ensembl_gene_id",
values = unique(vole_homolgsPage_fixed$hsapiens_homolog_ensembl_gene),
mart=human)vole_featurePage_uniq <- vole_featurePage %>%
group_by(ensembl_gene_id) %>%
reframe(entrezgene_ids = paste(entrezgene_id, collapse=", "),
external_gene_names = paste(external_gene_name, collapse=", "),
gene_biotype = gene_biotype[[1]],
entrezgene_id = entrezgene_id[[1]],
external_gene_name = external_gene_name[[1]]) %>%
unique()
mouse_featurePage_uniq <- mouse_featurePage %>%
group_by(ensembl_gene_id) %>%
reframe(mmusculus_entrezgene_ids = paste(entrezgene_id, collapse=", "),
mmusculus_entrezgene_id = entrezgene_id[[1]],
mmusculus_homolog_ensembl_gene = ensembl_gene_id) %>%
unique()
human_featurePage_uniq <- human_featurePage %>%
group_by(ensembl_gene_id) %>%
reframe(hsapiens_entrezgene_ids = paste(entrezgene_id, collapse=", "),
hsapiens_entrezgene_id = entrezgene_id[[1]],
hsapiens_homolog_ensembl_gene = ensembl_gene_id) %>%
unique()m0 <- full_join(vole_featurePage_uniq, vole_homolgsPage_fixed)
m1 <- full_join(m0, mouse_featurePage_uniq[,2:4])
m2 <- full_join(m1, human_featurePage_uniq[,2:4])
table(duplicated(m2$ensembl_gene_id))
#FALSE
#23038
write.csv(m2, file=paste0(data_dir, "vole_annotation.csv"))vole_annotation <- read.csv(paste0(data_dir, "vole_annotation.csv"), row.names = 1) QC, Filtering, and Data Viz
Based on clustering with a separate dataset not discussed here, we discovered one of the samples is actually from a different brain region. Removing KB11 before our normalization.
cts <- cts[,colnames(cts) %ni% c("KB11_WT_Post_M")]
metadata <- metadata[rownames(metadata) %ni% c("KB11_WT_Post_M"),]
qc_df <- qc_df[,colnames(qc_df) %ni% c("KB11_WT_Post_M")]#Is there anything concerning in how the reads were mapped to the genome?
#no.
par(cex=1, mar = c(10,5,3,1), xpd=TRUE)
a<- as.matrix(qc_df[rownames(qc_df) %in% c("N_reads_mapped", "N_unmapped","N_multimapping","N_noFeature","N_ambiguous"),])
barplot(a, main="Breakdown of Read distribution by sample",
col=c("orange","pink", "red","green","darkblue"),
legend = rownames(a),
las=2,
args.legend = list(x="bottomright", cex=0.5) )
pca <- prcomp(t(qc_df), center = T, scale. = T)
percentVar <- pca$sdev^2/sum(pca$sdev^2)
metadata %>%
mutate(PC1 = pca$x[, 1], PC2 = pca$x[, 2]) %>%
ggplot(aes(x = PC1, y = PC2, color=SeqRun, shape=species, label=SampleID)) +
geom_point(size = 3) +
coord_fixed() + theme_bw() +
xlab(paste0("PC1: ", round(percentVar[1] * 100), "% variance")) +
ylab(paste0("PC2: ", round(percentVar[2] * 100), "% variance")) +
ggtitle("PCA of QC metrics") +
geom_text(size=4, nudge_x = 0.5)
ggbiplot(pca) + theme_bw() + ggtitle("Biplot showing qc metrics + loadings")
Filter zero + lowly expressed genes out.
amanda.plot.density <- function(df, title, my.ylim, my.xlim){
library(RColorBrewer)
colramp= colorRampPalette(brewer.pal(4, "BuPu"))(ncol(df))
plot(density(df[,1]),col="white",lwd=3,ylim=my.ylim, xlim=my.xlim, main=title)
for(i in 1:ncol(df)){lines(density(df[,i]),lwd=1,col=colramp[i])}
}par(cex=1, mar = c(3,3,3,3), xpd=FALSE, mfrow=c(3,1))
cpm <- apply(cts,2, function(x) (x/sum(x))*1000000)
amanda.plot.density(log2(cpm + 1),
title=paste0("Original counts (n=",dim(cpm)[1],")"),
my.ylim =c(0,0.5), my.xlim= c(-1,15))
cpm <- cpm[rowSums(cpm) > 0,]
amanda.plot.density(log2(cpm + 1),
title=paste0("Zero removed counts (n=",dim(cpm)[1],")"),
my.ylim =c(0,0.5), my.xlim= c(-1,15))
cpm <- cpm[rowSums(cpm > 2) >= 3,]
amanda.plot.density(log2(cpm + 1),
title=paste0("LowExpr filtered counts (n=",dim(cpm)[1],")\n[required > 2 cpm in >= 3 samples]"),
my.ylim =c(0,0.5), my.xlim= c(-1,15))
norm_counts <- log2(cpm + 1)
cts <- cts[rownames(cts) %in% rownames(norm_counts), ] #remove those filtered out. pca <- prcomp(t(norm_counts), center = T)
percentVar <- pca$sdev^2/sum(pca$sdev^2)
pc1lab = paste0("PC1: ", round(percentVar[1] * 100), "% variance");
pc2lab = paste0("PC2: ", round(percentVar[2] * 100), "% variance")
cts_pca = metadata %>% mutate(PC1 = pca$x[, 1], PC2 = pca$x[, 2])ggplot(cts_pca, aes(x = PC1, y = PC2, color=SeqRun, shape=species, label=SampleID)) +
geom_point(size = 3) + coord_fixed() + xlab(pc1lab) + ylab(pc2lab) + theme_bw() +
ggtitle("Initial PCA") +
geom_text(size=4, nudge_x = 0.5)
ggplot(cts_pca, aes(x = PC1, y = PC2, color=species, shape=SeqRun, label=SampleID)) +
geom_point(size = 3) + coord_fixed() + xlab(pc1lab) + ylab(pc2lab) + theme_bw() +
ggtitle("Initial PCA: KO effect clear")
How did our technical replicates fair?
cts_pca$Pairs <- "NA"
cts_pca[cts_pca$SampleID %in% c("KB02","KB26"), "Pairs"] <- 1
cts_pca[cts_pca$SampleID %in% c("KB06","KB27"), "Pairs"] <- 2
cts_pca[cts_pca$SampleID %in% c("KB17","KB29"), "Pairs"] <- 3
cts_pca[cts_pca$SampleID %in% c("KB20","KB28"), "Pairs"] <- 4
cts_pca[cts_pca$Pairs != "NA", c("SampleID", "Pairs")] %>% arrange(Pairs)## SampleID Pairs
## KB02_WT_Pre_F KB02 1
## KB26_WT_Pre_F KB26 1
## KB06_WT_Pre_M KB06 2
## KB27_WT_Pre_M KB27 2
## KB17_Mut6_Pre_M KB17 3
## KB29_Mut6_Pre_M KB29 3
## KB20_Mut6_Post_F KB20 4
## KB28_Mut6_Post_F KB28 4ggplot(cts_pca, aes(x = PC1, y = PC2, color=Pairs, shape=SeqRun)) +
geom_point(size = 3) + coord_fixed() + xlab(pc1lab) + ylab(pc2lab) + theme_bw() +
ggtitle("Technical Replicates cluster with mate") +
scale_color_manual(values=c("#F8766D", "#D89000", "#00B0F6", "#9590FF", "black")) +
ggrepel::geom_text_repel(data=cts_pca[!is.na(cts_pca$TechnicalRep),], aes(label=SampleID), nudge_x= 2, show.legend = F, size=3)
#How is the data structured if we look at the groups of samples?
ggplot(cts_pca, aes(x = PC1, y = PC2, color=Group, shape=SeqRun, label=SampleID)) +
geom_point(size = 3) + coord_fixed() + xlab(pc1lab) + ylab(pc2lab) + theme_bw() +
ggtitle("PCA colored by sample group") +
ggrepel::geom_text_repel(nudge_x= 1, show.legend = F, size=3)
#very ugly code, sorry everyone.
norm_counts_aveTechRep <- as.data.frame(norm_counts)
norm_counts_aveTechRep[,"KB0226_WT_Pre_F"] <- unlist(rowMeans(norm_counts_aveTechRep[,c("KB02_WT_Pre_F", "KB26_WT_Pre_F")]))
norm_counts_aveTechRep[,"KB0627_WT_Pre_M"] <- unlist(rowMeans(norm_counts_aveTechRep[,c("KB06_WT_Pre_M", "KB27_WT_Pre_M")]))
norm_counts_aveTechRep[,"KB1729_Mut6_Pre_M"] <- unlist(rowMeans(norm_counts_aveTechRep[,c("KB17_Mut6_Pre_M", "KB29_Mut6_Pre_M")]))
norm_counts_aveTechRep[,"KB2028_Mut6_Post_F"] <- unlist(rowMeans(norm_counts_aveTechRep[,c("KB20_Mut6_Post_F", "KB28_Mut6_Post_F")]))
norm_counts_aveTechRep <- norm_counts_aveTechRep[, !colnames(norm_counts_aveTechRep) %in% c("KB02_WT_Pre_F", "KB26_WT_Pre_F","KB06_WT_Pre_M", "KB27_WT_Pre_M", "KB17_Mut6_Pre_M", "KB29_Mut6_Pre_M", "KB20_Mut6_Post_F", "KB28_Mut6_Post_F")]
dim(norm_counts_aveTechRep)## [1] 13324 31pca <- prcomp(t(norm_counts_aveTechRep), center = T)
percentVar <- pca$sdev^2/sum(pca$sdev^2)
pc1lab = paste0("PC1: ", round(percentVar[1] * 100), "% variance");
pc2lab = paste0("PC2: ", round(percentVar[2] * 100), "% variance")
tmp <- data.frame(PC1 = pca$x[, 1], PC2 = pca$x[, 2])
tmp$name = rownames(tmp)
tmp$group = as.factor(
sapply(strsplit(tmp$name, "_", fixed=T), function(x) paste0(x[[2]],x[[4]]))
)
tmp$group <- factor(tmp$group, levels = c("WTF", "WTM","Mut6F","Mut6M"))
tmp$Condition = as.factor(
sapply(strsplit(tmp$name, "_", fixed=T), function(x) x[[3]])
)
tmp$Condition <- factor(tmp$Condition, levels = c("Pre", "Post"))
g1 <- ggplot(tmp, aes(x = PC1, y = PC2, color=group, shape=Condition)) +
geom_point(size = 5) + coord_fixed() + xlab(pc1lab) + ylab(pc2lab) +
theme_bw() +
ggtitle("Principal Component Analysis of RNA-seq") +
scale_shape_manual(values=c(16, 17), name="",
lab=c("pre-pairing", "post-pairing")) +
scale_color_manual(values=c("#bf083d", "#2b4599", "#ff96a1", "#b3ccff"), name="",
lab=c("WT female", "WT male", expression(bold(OXTR^"1-/-"~female)), expression(bold(OXTR^"1-/-"~male)))) +
theme(text=element_text(size=14, face = "bold"),
legend.text.align = 0)## Warning: The `legend.text.align` argument of `theme()` is deprecated as of ggplot2
## 3.5.0.
## ℹ Please use theme(legend.text = element_text(hjust)) instead.
## This warning is displayed once every 8 hours.
## Call `lifecycle::last_lifecycle_warnings()` to see where this warning was
## generated.ggsave(plot=g1, file=paste0(output_dir, "figures/Supp5A_PCA.svg"), width=10, height=10)
g1
PCAs split by Mutation status
amanda_quickPCA <- function(keep, my_color="Condition", my_shape="species"){
my_color=sym(my_color); my_shape=sym(my_shape)
pca <- prcomp(t(norm_counts[, colnames(norm_counts) %in% keep ]), center = T)
percentVar <- pca$sdev^2/sum(pca$sdev^2)
g1 <- metadata %>%
filter(FullID %in% keep) %>%
mutate(PC1 = pca$x[, 1], PC2 = pca$x[, 2]) %>%
ggplot(aes(x = PC1, y = PC2, label=FullID, color=!!my_color, shape=!!my_shape)) +
geom_point(size = 3) + theme_bw() +
xlab(paste0("PC1: ", round(percentVar[1] * 100), "% variance")) +
ylab(paste0("PC2: ", round(percentVar[2] * 100), "% variance")) +
ggrepel::geom_text_repel(nudge_x= 1, show.legend = F, size=3)
return(g1)
}g1 = amanda_quickPCA(keep = metadata %>% filter(species=="WT") %>% pull("FullID"), my_color="Sex", my_shape = "species") +
ggtitle("WT samples [F v M]")
g2 = amanda_quickPCA(keep = metadata %>% filter(species=="WT") %>% pull("FullID"), my_color="Condition", my_shape = "Sex") +
ggtitle("WT samples [Pre v Post]") + scale_color_manual(values=c("orange","purple"))
g3 = amanda_quickPCA(keep = metadata %>% filter(species=="Mut6") %>% pull("FullID"), my_color="Sex", my_shape = "species") +
ggtitle("Mut samples [F v M]")
g4 = amanda_quickPCA(keep = metadata %>% filter(species=="Mut6") %>% pull("FullID"), my_color="Condition", my_shape = "Sex") +
ggtitle("Mut samples [Pre v Post]") + scale_color_manual(values=c("orange","purple"))
grid.arrange(g1,g2, g3, g4, ncol=2)
PCAs split into subgroups
Note: plots are tiny but on html you can zoom in.
g1 = amanda_quickPCA(keep = metadata %>% filter(species=="WT", Sex=="F") %>% pull("FullID"),
my_color="Condition", my_shape = "species") +
ggtitle("WT Female [Pre v Post]") + scale_color_manual(values=c("orange","purple"))
g2 = amanda_quickPCA(keep = metadata %>% filter(species=="WT", Sex=="M") %>% pull("FullID"),
my_color="Condition", my_shape = "species") +
ggtitle("WT Male [Pre v Post]") + scale_color_manual(values=c("orange","purple"))
g3 = amanda_quickPCA(keep = metadata %>% filter(species=="Mut6", Sex=="F") %>% pull("FullID"),
my_color="Condition", my_shape = "species") +
ggtitle("Mut Female [Pre v Post]") + scale_color_manual(values=c("orange","purple"))
g4 = amanda_quickPCA(keep = metadata %>% filter(species=="Mut6", Sex=="M") %>% pull("FullID"),
my_color="Condition", my_shape = "species") +
ggtitle("Mut Male [Pre v Post]") + scale_color_manual(values=c("orange","purple"))
grid.arrange(g1,g2,g3,g4, ncol=4)
g1 = amanda_quickPCA(keep = metadata %>% filter(species=="WT", Condition=="Pre-bond") %>% pull("FullID"),
my_color="Sex", my_shape = "species") +
ggtitle("WT Pre-bond [F v M]")
g2 = amanda_quickPCA(keep = metadata %>% filter(species=="WT", Condition=="Post-bond") %>% pull("FullID"),
my_color="Sex", my_shape = "species") +
ggtitle("WT Post-bond [F v M]")
g3 = amanda_quickPCA(keep = metadata %>% filter(species=="Mut6", Condition=="Pre-bond") %>% pull("FullID"),
my_color="Sex", my_shape = "species") +
ggtitle("Mut Pre-bond [F v M]")
g4 = amanda_quickPCA(keep = metadata %>% filter(species=="Mut6", Condition=="Post-bond") %>% pull("FullID"),
my_color="Sex", my_shape = "species") +
ggtitle("Mut Post-bond [F v M]")
grid.arrange(g1,g2,g3,g4, ncol=4)
Let’s save our normalized + filtered counts.
#write.csv(cts, file=paste0(output_dir, "filtered_counts.csv"))
write.csv(norm_counts, file=paste0(output_dir, "norm_counts.csv"))print("Summary: No noticeable outliers by either QC metrics or gene expression. Technical replicates all cluster with mate. Slight effect of sequencing batch to control for. Based on PCA, there seems to be a moderate effect of the mutation and less for bonding -- this should be reflected in the DEX.")## [1] "Summary: No noticeable outliers by either QC metrics or gene expression. Technical replicates all cluster with mate. Slight effect of sequencing batch to control for. Based on PCA, there seems to be a moderate effect of the mutation and less for bonding -- this should be reflected in the DEX."Differential Expression
There are three things we need to take into account:
- Unwanted variation by sequencing batch
- Collapsing technical replicates
- DESeq2 model w/ 3 interaction terms
Control for Sequencing Batch
- Option A is to recode the Sequencing Batch from 1/2/3 as a/b/c and add
it into the deseq2 model.
- Option B is to estimate a continuous factor of unwanted variation
(sequencing batch + other things we don’t know about). I prefer option B
because our model matrix might get complicated in deseq2 and it will be
easier if this is continuous.
set <- newSeqExpressionSet(as.matrix(cts), phenoData = metadata)
x = as.factor(metadata$SeqRun) #unwanted variation we're aware of.
colors <- brewer.pal(length(unique(x)), "Set2")
set1 <- betweenLaneNormalization(set, which="upper")
#What does our data look like now.
#par(cex=1, mar = c(3,3,3,3), xpd=FALSE, mfrow=c(2,1))
#plotRLE(set, outline=FALSE, ylim=c(-4, 4), col=colors[x])
#plotRLE(set1, outline=FALSE, ylim=c(-4, 4), col=colors[x], las=2)#Estimating factors using replicates
set2 <- RUVs(set1, rownames(cts), k=1, makeGroups(metadata$Group))
#Estimating factors using residuals
design <- model.matrix(~Group, data=pData(set))
y <- DGEList(counts=counts(set), group=x)
y <- calcNormFactors(y, method="upperquartile")
y <- estimateGLMCommonDisp(y, design)
y <- estimateGLMTagwiseDisp(y, design)
fit <- glmFit(y, design)
res <- residuals(fit, type="deviance")
set3 <- RUVr(set1, rownames(cts), k=1, res)
par(cex=1, mar = c(3,3,3,3), xpd=FALSE, mfrow=c(1,3))
plotPCA(set1, col=colors[x], cex=0.8) + title("Before")
plotPCA(set2, col=colors[x], cex=0.8) + title("RUVs -- replicates")
plotPCA(set3, col=colors[x], cex=0.8) + title("RUVr -- residuals")
Technical Replicates
- “collapseReplicates can assist in combining the counts from technical
replicates into single columns of the count matrix.” – deseq2
DESeq2 model
- In an initial version of this I used the full three factor linear
model
y=\(\beta_{0}\) + \(\beta_{1}\)Batch + \(\beta_{2}\)Genotype + \(\beta_{3}\)Bonding + \(\beta_{4}\)Sex + \(\beta_{5}\)Genotype:Bonding + \(\beta_{5}\)Genotype:Sex + \(\beta_{6}\)Bonding:Sex + \(\beta_{7}\)Genotype:Bonding:Sex
I found the 2nd and 3rd order interactions effect were small compared to the first order, so going forward I’m just going to make designs with group variables that fit each question.
#FUNCTIONS
amanda.volcano.plot <- function(results, title, gene.list=NA, FCcut = 0, Padjcut = 0.05){
results <- data.frame(results)
results <- results[!is.na(results$padj) & !is.na(results$log2FoldChange) ,]
results$sig <- as.factor(ifelse(results$padj <= Padjcut & abs(results$log2FoldChange) > FCcut, "sig", "notsig"))
to_label <- results[results$external_gene_name %in% gene.list, ]
p1 <- ggplot(results, aes(x=log2FoldChange, y=-log10(padj), col=sig)) +
geom_point(aes(color = sig)) +
ggtitle(title) +
xlab("log2FC") + ylab("-log10(padj)") +
scale_colour_manual(values = c("black", "red3"), name ="", labels=c("not signficant", "significant")) +
theme_bw() +
theme(legend.justification=c(1,0), legend.position=c(1,0), legend.title = element_blank(),
legend.background = element_rect(fill="transparent", linewidth=0.5, linetype="solid", color = "black")) +
ggrepel::geom_text_repel(data=to_label, aes(label=external_gene_name), show.legend = F, size=2) +
geom_vline(xintercept = c(FCcut,-1*FCcut), color="blue", linetype="dashed", linewidth=0.5) +
geom_hline(yintercept = -log10(Padjcut), color="blue", linetype="dashed", linewidth=0.5) +
NULL
return(p1)
}
amanda.quick.boxplots <- function(df, genename, my.title, group.var, my.order=NULL){
d<- data.frame(t(df[genename, , drop=F]))
d$group <- metadata[order(metadata$FullID[metadata$SampleID %in% rownames(d)], rownames(d)), group.var]
colnames(d) <- c("gene", "group")
d$group <- as.factor(d$group)
if (!is.null(my.order)){d$group <- factor(d$group, levels=my.order)}
g1 <- ggplot(d, aes(x=group, y=gene, fill=group)) +
geom_boxplot() +
geom_jitter(color="black", size=2, alpha=0.5, width = 0.1) +
ggtitle(my.title) +
ylab("Normalized Gene Expression") +
xlab("") +
theme_bw() +
theme(plot.title = element_text(hjust = 0.5, face="bold", size=12),
legend.position = "none", axis.text.x = element_text(angle = 45, hjust = 1)) +
NULL
return(g1)
}#Data cleaning for deseq
#swap characters so deseq doesn't yell at me.
pData(set3)[, "Condition"] <- gsub("-", "_", pData(set3)[, "Condition"])
keep = c("species", "Condition", "Sex")
pData(set3)[,keep] <- lapply(pData(set3)[,keep] , factor)
pData(set3)[,"species"] <- relevel(pData(set3)[,"species"], ref = "WT")
pData(set3)[,"Condition"] <- relevel(pData(set3)[,"Condition"], ref = "Pre_bond")
pData(set3)[,"Sex"] <- relevel(pData(set3)[,"Sex"], ref = "F")
#Make a column so we can collapse technical replicates later
pData(set3)[pData(set3)$SampleID == "KB29", ]$SampleID <- "KB17"
pData(set3)[pData(set3)$SampleID == "KB28", ]$SampleID <- "KB20"
pData(set3)[pData(set3)$SampleID == "KB27", ]$SampleID <- "KB06"
pData(set3)[pData(set3)$SampleID == "KB26", ]$SampleID <- "KB02"Q1: What is the bonding effect?
y =\(\beta_{0}\) + \(\beta_{1}\)Batch + \(\beta_{2}\)Bonding
dds <- DESeqDataSetFromMatrix(countData = counts(set3), colData = pData(set3), design = ~ W_1 + Condition )
dds <- collapseReplicates(dds, groupby = dds$SampleID)
dds <- DESeq(dds)
ddsnorm <- counts(dds, normalized=TRUE)res = lfcShrink(dds, type="ashr", contrast=list(c("Condition_Post_bond_vs_Pre_bond")), quiet = TRUE)
mydf <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
left_join(vole_annotation, by="ensembl_gene_id")
sig_joint <- mydf %>% filter(!is.na(padj), padj < 0.05) %>% arrange(padj)bonding_df <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(bonding_df) <- paste0(colnames(bonding_df), "_joint")
bonding_df$ensembl_gene_id = rownames(res)metadata$tmp <- paste0(metadata$species, "_", metadata$Sex, "_", metadata$Condition)
myorder = c('WT_F_Pre-bond' ,'WT_F_Post-bond', 'WT_M_Pre-bond', 'WT_M_Post-bond' ,
'Mut6_F_Pre-bond', 'Mut6_F_Post-bond' ,'Mut6_M_Pre-bond', 'Mut6_M_Post-bond')
myorder2 = c("Pre-bond", "Post-bond")DEX Table
cat("Number of DEX genes:", nrow(sig_joint))## Number of DEX genes: 13sig_joint %>%
kbl() %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed")) %>%
scroll_box(width = "800px", height = "400px")| ensembl_gene_id | baseMean | log2FoldChange | lfcSE | pvalue | padj | entrezgene_ids | external_gene_names | gene_biotype | entrezgene_id | external_gene_name | mmusculus_homolog_ensembl_gene | mmusculus_homolog_associated_gene_name | mmusculus_homolog_orthology_type | mmusculus_homolog_perc_id | hsapiens_homolog_ensembl_gene | hsapiens_homolog_associated_gene_name | hsapiens_homolog_orthology_type | hsapiens_homolog_perc_id | mmusculus_homolog_ensembl_genes | mmusculus_homolog_associated_gene_names | mmusculus_homolog_perc_ids | hsapiens_homolog_ensembl_genes | hsapiens_homolog_associated_gene_names | hsapiens_homolog_perc_ids | mmusculus_entrezgene_ids | mmusculus_entrezgene_id | hsapiens_entrezgene_ids | hsapiens_entrezgene_id |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ENSMOCG00000008011 | 1006.6700 | -0.4276940 | 0.0947017 | 2.00e-07 | 0.0024537 | 101990550 | Sgk1 | protein_coding | 101990550 | Sgk1 | ENSMUSG00000019970 | Sgk1 | ortholog_one2one | 89.2135 | ENSG00000118515 | SGK1 | ortholog_one2one | 89.4382 | NA | NA | NA | NA | NA | NA | 20393 | 20393 | 6446 | 6446 |
| ENSMOCG00000021476 | 2882.0003 | -0.5307221 | 0.1577762 | 6.00e-07 | 0.0033414 | 101980199 | Agt | protein_coding | 101980199 | Agt | ENSMUSG00000031980 | Agt | ortholog_one2one | 80.9129 | ENSG00000135744 | AGT | ortholog_one2one | 63.2780 | NA | NA | NA | NA | NA | NA | 11606 | 11606 | 183 | 183 |
| ENSMOCG00000001596 | 136.3246 | -0.4068979 | 0.1329794 | 2.00e-06 | 0.0071968 | 101982079 | Fosb | protein_coding | 101982079 | Fosb | ENSMUSG00000003545 | Fosb | ortholog_one2one | 98.5207 | ENSG00000125740 | FOSB | ortholog_one2one | 96.4497 | NA | NA | NA | NA | NA | NA | 14282 | 14282 | 2354 | 2354 |
| ENSMOCG00000022242 | 155.4129 | -0.3675114 | 0.1722808 | 6.30e-06 | 0.0132565 | 101999004 | Nfkbia | protein_coding | 101999004 | Nfkbia | ENSMUSG00000021025 | Nfkbia | ortholog_one2one | 95.8599 | ENSG00000100906 | NFKBIA | ortholog_one2one | 91.7197 | NA | NA | NA | NA | NA | NA | 18035 | 18035 | 4792 | 4792 |
| ENSMOCG00000010654 | 728.8035 | -0.1689569 | 0.0846489 | 9.60e-06 | 0.0132565 | 101986045 | Kcnk1 | protein_coding | 101986045 | Kcnk1 | ENSMUSG00000033998 | Kcnk1 | ortholog_one2one | 97.6190 | ENSG00000135750 | KCNK1 | ortholog_one2one | 96.4286 | NA | NA | NA | NA | NA | NA | 16525 | 16525 | 3775 | 3775 |
| ENSMOCG00000010316 | 2803.7236 | -0.4079354 | 0.2272343 | 6.10e-06 | 0.0132565 | 101989913 | Ptgds | protein_coding | 101989913 | Ptgds | ENSMUSG00000015090 | Ptgds | ortholog_one2one | 86.3874 | ENSG00000107317 | PTGDS | ortholog_one2one | 70.1571 | NA | NA | NA | NA | NA | NA | 19215 | 19215 | 5730 | 5730 |
| ENSMOCG00000019331 | 139.3279 | -0.3714108 | 0.2074278 | 8.40e-06 | 0.0132565 | 101991170 | Acsm5 | protein_coding | 101991170 | Acsm5 | ENSMUSG00000030972 | Acsm5 | ortholog_one2one | 93.0796 | ENSG00000183549 | ACSM5 | ortholog_one2one | 84.2561 | NA | NA | NA | NA | NA | NA | 272428 | 272428 | 54988 | 54988 |
| ENSMOCG00000011306 | 178.4914 | -0.3775135 | 0.2500283 | 8.90e-06 | 0.0132565 | 101999815 | Pdk4 | protein_coding | 101999815 | Pdk4 | ENSMUSG00000019577 | Pdk4 | ortholog_one2one | 96.6019 | ENSG00000004799 | PDK4 | ortholog_one2one | 91.9903 | NA | NA | NA | NA | NA | NA | 27273 | 27273 | 5166 | 5166 |
| ENSMOCG00000011232 | 3168.3276 | -0.0864964 | 0.0372613 | 1.32e-05 | 0.0161315 | 101991138 | Kidins220 | protein_coding | 101991138 | Kidins220 | ENSMUSG00000036333 | Kidins220 | ortholog_one2one | 96.2075 | ENSG00000134313 | KIDINS220 | ortholog_one2one | 92.8054 | NA | NA | NA | NA | NA | NA | 77480 | 77480 | 57498 | 57498 |
| ENSMOCG00000000666 | 291.0633 | -0.1658812 | 0.1263209 | 3.20e-05 | 0.0351512 | 101990188 | Mertk | protein_coding | 101990188 | Mertk | ENSMUSG00000014361 | Mertk | ortholog_one2one | 88.7538 | ENSG00000153208 | MERTK | ortholog_one2one | 80.6484 | NA | NA | NA | NA | NA | NA | 17289 | 17289 | 10461 | 10461 |
| ENSMOCG00000017685 | 137.5705 | -0.2324423 | 0.2365139 | 3.96e-05 | 0.0396043 | 102000436 | Heph | protein_coding | 102000436 | Heph | ENSMUSG00000031209 | Heph | ortholog_one2one | 90.0691 | ENSG00000089472 | HEPH | ortholog_one2one | 85.4922 | NA | NA | NA | NA | NA | NA | 15203 | 15203 | 9843 | 9843 |
| ENSMOCG00000015375 | 241.2458 | -0.1995635 | 0.1993981 | 5.22e-05 | 0.0478097 | 101989969 | Txnip | protein_coding | 101989969 | Txnip | ENSMUSG00000038393 | Txnip | ortholog_one2one | 97.7215 | ENSG00000265972 | TXNIP | ortholog_one2one | 95.4430 | NA | NA | NA | NA | NA | NA | 56338 | 56338 | 10628 | 10628 |
| ENSMOCG00000018062 | 147.3422 | -0.1888598 | 0.1979510 | 5.89e-05 | 0.0498542 | 113455429 | Prr5 | protein_coding | 113455429 | Prr5 | ENSMUSG00000036106 | Prr5 | ortholog_one2one | 95.8656 | ENSG00000186654 | PRR5 | ortholog_one2one | 89.6641 | NA | NA | NA | NA | NA | NA | 109270 | 109270 | 55615 | 55615 |
Volcano Plot
amanda.volcano.plot(mydf, title = " ",
gene.list = mydf %>% arrange(padj) %>% head(n=25) %>% pull(external_gene_name),
FCcut = 0)## Warning: A numeric `legend.position` argument in `theme()` was deprecated in ggplot2
## 3.5.0.
## ℹ Please use the `legend.position.inside` argument of `theme()` instead.
## This warning is displayed once every 8 hours.
## Call `lifecycle::last_lifecycle_warnings()` to see where this warning was
## generated.
Selected Gene Plot
id = sig_joint %>% arrange(desc(abs(log2FoldChange))) %>% head(n=6) %>% pull(ensembl_gene_id)
name = sig_joint %>% arrange(desc(abs(log2FoldChange))) %>% head(n=6) %>% pull(external_gene_name)
d <- ddsnorm %>%
data.frame() %>%
filter(row.names(ddsnorm) %in% id[1:6]) %>%
t() %>% data.frame() %>%
rownames_to_column() %>%
tidyr::pivot_longer(cols=-c(rowname), values_to='expr', names_to='gene') %>%
left_join(metadata[,c("SampleID", "Condition")], by=c("rowname"="SampleID")) %>%
left_join(vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("gene"="ensembl_gene_id"))
d$Condition <- as.factor(d$Condition)
d$Condition <- factor(d$Condition, levels=c("Pre-bond", "Post-bond"))
d$external_gene_name <- as.factor(d$external_gene_name)
d$external_gene_name <- factor(d$external_gene_name, levels=name)
g1 <- ggplot(d, aes(x=Condition, y=log2(expr), fill=Condition)) +
geom_boxplot() +
geom_jitter(color="black", size=2, alpha=0.5, width = 0.1) +
facet_wrap(~external_gene_name, scales = "free_y") +
theme_bw() + xlab("") +
ylab("log2 Normalized Gene Expression") +
ggtitle("Top 6 DE Genes in Pairing") +
scale_x_discrete(labels = c("pre-pairing", "post-pairing")) +
scale_fill_manual(values=c("#087B8B","#E5A024")) +
theme(text=element_text(size=14, face = "bold"),
strip.text.x = element_text(size = 16),
plot.title = element_text(hjust = 0.5),
legend.position = "none", axis.text.x = element_text(angle = 45, hjust = 1))
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig5C_BoxPlot.svg"), width=10, height=7)
g1
MA Plot
l = data.frame(res)
l$sig = ifelse(l$padj > 0.05 | is.na(l$padj), "NS", ifelse(l$log2FoldChange >0, "up", "down"))
l$sig <- as.factor(l$sig); l$sig <- factor(l$sig, levels=c("down", "up", "NS"))
l <- left_join(rownames_to_column(l), vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("rowname" = "ensembl_gene_id"))
g1 <- ggplot(l, aes(x=log2(baseMean), y=log2FoldChange, col=sig)) +
geom_point(size=4) +
scale_color_manual(values=c("#1465AC", "darkgray"), name="", lab=c(paste0("Down: ",table(l$sig)[["down"]]), "NS")) +
ylim(c(-0.6, 0.25)) +
theme_bw() +
xlab("Log2 Mean Expression") + ylab("Log2 Fold Change") +
ggtitle("Pre- vs Post-pairing MA plot") +
guides(color = guide_legend(direction = "horizontal")) +
ggrepel::geom_text_repel(data=l[l$rowname %in% id[1:6], ], aes(label=external_gene_name),
show.legend = F, size=4, box.padding = 0.5, segment.color = NA) +
theme(text=element_text(size=14, face = "bold"),
plot.title = element_text(hjust = 0.5),
legend.position=c(1, 1.03),
legend.justification="right")
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig5B_MAPlot.svg"), width=10, height=8)
g1
Is the bonding effect different by genotype?
- y = \(\beta_{0}\) + \(\beta_{1}\)Batch + \(\beta_{2}\)Genotype + \(\beta_{3}\)Bonding + \(\beta_{4}\)Genotype:Bonding
- In sum, most dex genes are driven by WT samples, but the trends are maintained in the oxtr -/- individuals. This makes me believe we should use the joint analysis for accuracy + to power our results.
dds <- DESeqDataSetFromMatrix(countData = counts(set3), colData = pData(set3),
design = ~ W_1 + species + Condition + species:Condition)
dds <- collapseReplicates(dds, groupby = dds$SampleID)
dds <- DESeq(dds)res = lfcShrink(dds, type="ashr", contrast=list(c("Condition_Post_bond_vs_Pre_bond")), quiet = TRUE)
sig_WT <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_WT")
bonding_df <- cbind(bonding_df, tmp)
res = lfcShrink(dds, type="ashr", contrast=list(c("Condition_Post_bond_vs_Pre_bond", "speciesMut6.ConditionPost_bond")), quiet = TRUE)
sig_MUT <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_MUT")
bonding_df <- cbind(bonding_df, tmp)x = list(
"joint"=sig_joint$ensembl_gene_id,
"WT"=sig_WT$ensembl_gene_id,
"MUT"=sig_MUT$ensembl_gene_id
)
g1 <- ggVennDiagram(x, label_alpha = 0, label="count") +
scale_fill_gradient(low="blue",high = "yellow") +
scale_color_manual(values = c(rep("black",3))) +
theme(legend.position="none") + ggtitle("Pre v Post bonding")tmp <- left_join(data.frame(bonding_df), vole_annotation, by="ensembl_gene_id")
tmp$sig <- "neither"
tmp[tmp$ensembl_gene_id %in% intersect(sig_joint$ensembl_gene_id, sig_WT$ensembl_gene_id), "sig"] <- "both"
tmp[tmp$ensembl_gene_id %in% setdiff(sig_joint$ensembl_gene_id, sig_WT$ensembl_gene_id), "sig"] <- "joint"
tmp[tmp$ensembl_gene_id %in% setdiff(sig_WT$ensembl_gene_id, sig_joint$ensembl_gene_id), "sig"] <- "WT_only"
tmp$sig <- as.factor(tmp$sig)
tmp$sig <- factor(tmp$sig, levels = c("both","joint", "WT_only", "neither"))
tolabel <- tmp[tmp$sig %ni% "neither", ]
tolabel$tmp <- ifelse(tolabel$external_gene_name == "", tolabel$ensembl_gene_id, tolabel$external_gene_name)
g2 <- ggplot(tmp, aes(x=abs(log2FoldChange_joint), y=abs(log2FoldChange_WT), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
ylim(c(0,1)) + xlim(c(0,1)) +
scale_color_manual(values=c("#E69F00", "#56B4E9", "darkgreen", "#DDDDDD"), name = "significance @ \npadj < 0.05") +
ggrepel::geom_text_repel(data=tolabel, aes(label=tmp), show.legend = F, size=2) grid.arrange(g1,g2,ncol=2, widths=c(1,3))
Is the bonding effect different by sex?
- y = \(\beta_{0}\) + \(\beta_{1}\)Batch + \(\beta_{2}\)Sex + \(\beta_{3}\)Bonding + \(\beta_{4}\)Sex:Bonding
- In sum, most dex genes are driven by female samples, but the trends are maintained in the male samples. This makes me believe we should use the joint analysis for accuracy + to power our results. The magnitude may just change across sexes.
dds <- DESeqDataSetFromMatrix(countData = counts(set3), colData = pData(set3),
design = ~ W_1 + Sex + Condition + Sex:Condition)
dds <- collapseReplicates(dds, groupby = dds$SampleID)
dds <- DESeq(dds)res = lfcShrink(dds, type="ashr", contrast=list(c("Condition_Post_bond_vs_Pre_bond")), quiet = TRUE)
sig_F <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_F")
bonding_df <- cbind(bonding_df, tmp)
res = lfcShrink(dds, type="ashr", contrast=list(c("Condition_Post_bond_vs_Pre_bond", "SexM.ConditionPost_bond")), quiet = TRUE)
sig_M <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_M")
bonding_df <- cbind(bonding_df, tmp)x = list(
"F+M"=sig_joint$ensembl_gene_id,
"F"=sig_F$ensembl_gene_id,
"M"=sig_M$ensembl_gene_id
)
g1 <- ggvenn(x, fill_color = c("#96D3BA", "#F36D42", "#6F5DA8"), show_percentage = FALSE, text_size = 6, set_name_size = 5)tmp <- left_join(data.frame(bonding_df), vole_annotation, by="ensembl_gene_id")
tmp$sig <- "neither"
tmp[tmp$ensembl_gene_id %in% intersect(sig_joint$ensembl_gene_id, sig_F$ensembl_gene_id), "sig"] <- "both"
tmp[tmp$ensembl_gene_id %in% setdiff(sig_joint$ensembl_gene_id, sig_F$ensembl_gene_id), "sig"] <- "joint"
tmp[tmp$ensembl_gene_id %in% setdiff(sig_F$ensembl_gene_id, sig_joint$ensembl_gene_id), "sig"] <- "female_only"
tmp$sig <- as.factor(tmp$sig)
tmp$sig <- factor(tmp$sig, levels = c("joint", "both","female_only", "neither"))
tolabel <- tmp[tmp$sig %ni% "neither", ]
#tolabel$tmp <- ifelse(tolabel$external_gene_name == "", tolabel$ensembl_gene_id, tolabel$external_gene_name)
g2 <- ggplot(tmp, aes(y=abs(log2FoldChange_joint), x=abs(log2FoldChange_F), color=sig)) +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.3) +
geom_point(size=4) + theme_bw() +
ylim(c(0,0.8)) + xlim(c(0,0.8)) +
xlab("Absolute Log2 Fold-change (F only)") + ylab("Absolute Log2 Fold-change (F+M)") +
ggtitle("Pre- vs Post-pairing show sex-specific effect sizes") +
scale_color_manual(values=c("#96D3BA","#B1AD57", "#F36D42", "darkgrey"),
lab=c(paste0("F+M (", table(tmp$sig)[[1]],")"),
paste0("F and F+M (", table(tmp$sig)[[2]],")"),
paste0("F only (", table(tmp$sig)[[3]],")"),
"NS"),
name = "DEX list") +
ggrepel::geom_text_repel(data=tolabel, aes(label=external_gene_name),
show.legend = F, size=3, box.padding = 0.3, segment.color = NA) +
theme(text=element_text(size=14, face = "bold"),
plot.title = element_text(hjust = 0.5))
ggsave(plot=grid.arrange(g1,g2,ncol=2, widths=c(1,3)),
file=paste0(output_dir, "figures/Fig5D.svg"), width=12, height=7)
grid.arrange(g1,g2,ncol=2, widths=c(1,3))
Is the bonding effect different by sex+genotype?
- From above we know its WT females driving our effect.
pData(set3)$group <- paste0(pData(set3)$species, "_", pData(set3)$Sex, "_", gsub("_bond", "", pData(set3)$Condition))
pData(set3)$group <- as.factor(pData(set3)$group)
pData(set3)[,"group"] <- relevel(pData(set3)[,"group"], ref = "WT_F_Pre")
dds <- DESeqDataSetFromMatrix(countData = counts(set3), colData = pData(set3), design = ~ W_1 + group)
dds <- collapseReplicates(dds, groupby = dds$SampleID)
dds <- DESeq(dds)res = lfcShrink(dds, type="ashr", contrast=c("group", "WT_F_Post", "WT_F_Pre"), quiet = TRUE)
sig_WTF <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_WTF")
bonding_df <- cbind(bonding_df, tmp)
res = lfcShrink(dds, type="ashr", contrast=c("group", "WT_M_Post", "WT_M_Pre"), quiet = TRUE)
sig_WTM <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_WTM")
bonding_df <- cbind(bonding_df, tmp)
res = lfcShrink(dds, type="ashr", contrast=c("group", "Mut6_F_Post", "Mut6_F_Pre"), quiet = TRUE)
sig_MUTF <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_MUTF")
bonding_df <- cbind(bonding_df, tmp)
res = lfcShrink(dds, type="ashr", contrast=c("group", "Mut6_M_Post", "Mut6_M_Pre"), quiet = TRUE)
sig_MUTM <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
filter(!is.na(padj), padj < 0.05)
tmp <- res[, c("log2FoldChange", "padj", "lfcSE")]; colnames(tmp) <- paste0(colnames(tmp), "_MUTM")
bonding_df <- cbind(bonding_df, tmp)x = list(
"WT_M"=sig_WTM$ensembl_gene_id,
"WT_F"=sig_WTF$ensembl_gene_id,
"MUT_M"=sig_MUTM$ensembl_gene_id,
"MUT_F"=sig_MUTF$ensembl_gene_id
)
g1 <- ggVennDiagram(x, label_alpha = 0, label="count") +
scale_fill_gradient(low="blue",high = "yellow") +
scale_color_manual(values = c(rep("black",4))) +
theme(legend.position="none") + ggtitle("Pre v Post bonding")
x = list(
"group_unions"=unique(c(sig_WTM$ensembl_gene_id, sig_WTF$ensembl_gene_id,
sig_MUTM$ensembl_gene_id, sig_MUTF$ensembl_gene_id)),
"joint" = sig_joint$ensembl_gene_id
)
g2 <- ggVennDiagram(x, label_alpha = 0, label="count") +
scale_fill_gradient(low="blue",high = "yellow") +
scale_color_manual(values = c(rep("black",2))) +
theme(legend.position="none") + ggtitle("Pre v Post bonding")
grid.arrange(g1,g2, ncol=2)
{-}
MUT_M
- only two genes in the venn diagram above
- Sema3b seems strong and interesting. It can “function in growth cone guidance during neuronal development”
g1 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000010337", "ENSMOCG00000010337 (human ortho gapdh)", "tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000010337", "ENSMOCG00000010337 (human ortho gapdh)", "Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
g1 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000019704", "Sema3b", "tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000019704", "Sema3b", "Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
MUT_F
- four genes in the venn diagram above (one of which is Kdr – repeat of above)
sig_MUTF <- left_join(sig_MUTF, vole_annotation, by="ensembl_gene_id")i = 1
g1 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
i = 2
g1 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
i = 3
g1 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
i = 4
g1 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm,
sig_MUTF[i, "ensembl_gene_id"], sig_MUTF[i, "external_gene_name"],
"Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
WT_F
tmp <- left_join(data.frame(bonding_df), vole_annotation, by="ensembl_gene_id")
tmp$sig <- "neither"
tmp[tmp$ensembl_gene_id %in% intersect(sig_joint$ensembl_gene_id, sig_WTF$ensembl_gene_id), "sig"] <- "both"
tmp[tmp$ensembl_gene_id %in% setdiff(sig_joint$ensembl_gene_id, sig_WTF$ensembl_gene_id), "sig"] <- "joint"
tmp[tmp$ensembl_gene_id %in% setdiff(sig_WTF$ensembl_gene_id, sig_joint$ensembl_gene_id), "sig"] <- "WT_F"
tmp$sig <- as.factor(tmp$sig)
tmp$sig <- factor(tmp$sig, levels = c("both","joint", "WT_F", "neither"))
tolabel <- tmp[tmp$sig %ni% "neither", ]
tolabel$tmp <- ifelse(tolabel$external_gene_name == "", tolabel$ensembl_gene_id, tolabel$external_gene_name)
ggplot(tmp, aes(x=abs(log2FoldChange_joint), y=abs(log2FoldChange_WTF), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
ylim(c(0,1)) + xlim(c(0,1)) +
scale_color_manual(values=c("#E69F00", "#56B4E9", "darkgreen", "#DDDDDD"), name = "significance @ \np < 0.05") +
ggrepel::geom_text_repel(data=tolabel, aes(label=tmp), show.legend = F, size=2) ## Warning: ggrepel: 10 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
- We’ve seen Gjb6 and Paqr8 above and we’re shocked by it. Neither of these genes look good at all. Just how we’re slicing the data + variance
g1 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000012456", "Abca5", "tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000012456", "Abca5", "Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
g1 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000006294", "Selenop", "tmp", myorder) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 4)))
g2 <- amanda.quick.boxplots(ddsnorm, "ENSMOCG00000006294", "Selenop", "Condition", myorder2) +
scale_fill_manual(values=c(rep(c("#56B4E9","#E69F00"), 1)))
grid.arrange(g1,g2,ncol=2)
WT_M
- none
library(circlize)
mymat <- ddsnorm %>%
data.frame() %>%
filter(row.names(ddsnorm) %in% sig_joint$ensembl_gene_id) %>%
rownames_to_column() %>%
left_join(vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("rowname"="ensembl_gene_id")) %>%
mutate(longer=ifelse(external_gene_name != "", external_gene_name, ensembl_gene_id)) %>%
column_to_rownames('longer') %>% select(-c(external_gene_name, rowname))
scaled_mat = t(scale(t(mymat)))
ha = HeatmapAnnotation(
Pairing = tolower(gsub("_bond", "", colData(dds)$Condition)),
Genotype = ifelse(colData(dds)$species == "WT", "WT", "OXTR1-/-"),
Sex = colData(dds)$Sex,
col = list(
Genotype = c("WT" = "#774972", "OXTR1-/-"="#D089DA"),
Pairing = c("pre" = "#087B8B", "post" = "#E5A024"),
#Sex = c("F" = "#bf083d", "M"= "#2b4599")),
#Sex = c("F" = "#bf083d", "M"= "lightblue")),
Sex = c("F" = "black", "M"= "lightgrey")),
annotation_legend_param = list(
Pairing=list(at=c("pre","post"), nrow=1),
Genotype=list(at=c("WT","OXTR1-/-"), nrow=1),
Sex = list(at=c("F","M"), nrow=1)
)
)
#col_fun = colorRamp2(c(-2, 0, 2), c("#E5A024", "white", "#087B8B"))
#col_fun = colorRamp2(c(-2, 0, 2), hcl_palette = "Cork")
#col_fun = colorRamp2(c(-2, 0, 2), hcl_palette = "Blue-Red 3")
#https://jokergoo.github.io/2022/03/08/support-hcl-colormaps-in-complexheatmap/
ht <- Heatmap(scaled_mat, name = "Z-score", top_annotation = ha,
#col = col_fun,
show_column_names = FALSE, cluster_columns = TRUE,
heatmap_legend_param = list(direction="horizontal", nrow=1),
row_title = "DE Genes", row_title_rot = 90,
column_title = "Samples", column_title_rot = 0, column_title_side = "bottom",
use_raster = TRUE)## 'magick' package is suggested to install to give better rasterization.
##
## Set `ht_opt$message = FALSE` to turn off this message.pdf(file=paste0(output_dir, "figures/Supp5B_Heatmap.pdf"), height = 10, width = 10)
draw(ht, merge_legend = TRUE)
dev.off()## quartz_off_screen
## 2draw(ht, merge_legend = TRUE)
bonding_df <- data.frame(bonding_df)
d0 <- bonding_df %>%
select(c("ensembl_gene_id", colnames(bonding_df)[grep("log2FoldChange", colnames(bonding_df))])) %>%
tidyr::pivot_longer(cols = -c(ensembl_gene_id), values_to="log2FC", names_to="subgroup") %>%
mutate(subgroup=gsub("log2FoldChange_", "", subgroup))
d1 <- bonding_df %>%
select(c("ensembl_gene_id", colnames(bonding_df)[grep("padj", colnames(bonding_df))])) %>%
tidyr::pivot_longer(cols = -c(ensembl_gene_id), values_to="padj", names_to="subgroup") %>%
mutate(subgroup=gsub("padj_", "", subgroup))
d2 <- bonding_df %>%
select(c("ensembl_gene_id", colnames(bonding_df)[grep("lfcSE", colnames(bonding_df))])) %>%
tidyr::pivot_longer(cols = -c(ensembl_gene_id), values_to="lfcSE", names_to="subgroup") %>%
mutate(subgroup=gsub("lfcSE_", "", subgroup))
d <- join(d2, join(d0, d1, by=c("ensembl_gene_id", "subgroup")), by=c("ensembl_gene_id", "subgroup"))
d <- join(d, vole_annotation %>% select(ensembl_gene_id, external_gene_name), by="ensembl_gene_id")
d <- d[d$subgroup %ni% c("WT","MUT","F","M"),]
d$subgroup <- d$subgroup
d[d$subgroup == "WTF", "subgroup"] <- "WT females"
d[d$subgroup == "WTM", "subgroup"] <- "WT males"
d[d$subgroup == "MUTF", "subgroup"] <- "OXTR1 -/- females"
d[d$subgroup == "MUTM", "subgroup"] <- "OXTR1 -/- males"
d$subgroup <- factor(d$subgroup,
levels=c("joint", "WT females", "OXTR1 -/- females", "WT males", "OXTR1 -/- males"))
d$sig = ifelse(d$padj < 0.05 & !is.na(d$padj), TRUE, FALSE)
d$name <- ifelse(d$external_gene_name == "", d$ensembl_gene_id, d$external_gene_name)
barchart_subgroup_df <- dbonding_df <- data.frame(bonding_df)
d0 <- bonding_df %>%
select(c("ensembl_gene_id", colnames(bonding_df)[grep("log2FoldChange", colnames(bonding_df))])) %>%
tidyr::pivot_longer(cols = -c(ensembl_gene_id), values_to="log2FC", names_to="subgroup") %>%
mutate(subgroup=gsub("log2FoldChange_", "", subgroup))
d1 <- bonding_df %>%
select(c("ensembl_gene_id", colnames(bonding_df)[grep("padj", colnames(bonding_df))])) %>%
tidyr::pivot_longer(cols = -c(ensembl_gene_id), values_to="padj", names_to="subgroup") %>%
mutate(subgroup=gsub("padj_", "", subgroup))
d2 <- bonding_df %>%
select(c("ensembl_gene_id", colnames(bonding_df)[grep("lfcSE", colnames(bonding_df))])) %>%
tidyr::pivot_longer(cols = -c(ensembl_gene_id), values_to="lfcSE", names_to="subgroup") %>%
mutate(subgroup=gsub("lfcSE_", "", subgroup))
d <- join(d2, join(d0, d1, by=c("ensembl_gene_id", "subgroup")), by=c("ensembl_gene_id", "subgroup"))
d <- join(d, vole_annotation %>% select(ensembl_gene_id, external_gene_name), by="ensembl_gene_id")
d <- d[d$subgroup %in% c("F","M", "joint"),]
d$subgroup <- d$subgroup
d[d$subgroup == "F", "subgroup"] <- "female"
d[d$subgroup == "M", "subgroup"] <- "male"
d$subgroup <- factor(d$subgroup, levels=c("joint", "female", "male"))
d$sig = ifelse(d$padj < 0.05 & !is.na(d$padj), TRUE, FALSE)
d$name <- ifelse(d$external_gene_name == "", d$ensembl_gene_id, d$external_gene_name)
barchart_sex_df <- drelabel <- function(x){ format(x*-1, nsmall = 1)}
amanda_barchart_subgroup <- function(d, sig_extra, mytitle="", legend_title="subgroup", ybreaks=NULL,
cols = c("#bf083d", "#ff96a1", "#2b4599", "#b3ccff")){
my_max = d %>% filter(ensembl_gene_id %in% sig_extra) %>%
mutate(added = abs(log2FC) + lfcSE) %>% pull(added) %>% max() %>% round(1) + 0.1
myorder <- d %>% filter(ensembl_gene_id %in% sig_extra) %>%
filter(subgroup=="joint") %>% arrange(desc(abs(log2FC))) %>% pull(name) %>% as.factor()
d$name <- factor(d$name, levels=myorder)
if (is.null(ybreaks)) {ybreaks=seq(0, my_max, by=0.2)}
g1 <- d %>%
filter(ensembl_gene_id %in% sig_extra) %>%
filter(subgroup=="joint") %>%
mutate(dummy="dummy") %>%
ggplot(aes(x=dummy, y=abs(log2FC), fill=subgroup)) +
geom_bar(position = "dodge2", stat = "identity") +
geom_errorbar(aes(ymin=ifelse(abs(log2FC)-lfcSE < 0, 0, abs(log2FC)-lfcSE),
ymax=abs(log2FC)+lfcSE), width=.2, position="dodge2") +
#scale_fill_manual(values=c("#7A2048")) +
scale_fill_manual(values=c("#087B8B")) +
xlab("") + ggtitle(mytitle) + ylab("Absolute log2 Fold Change") +
scale_y_continuous(limits = c(min(ybreaks), max(ybreaks)), breaks = ybreaks, labels=relabel) +
theme_bw() +
geom_text(aes(y = abs(log2FC)+lfcSE, label = ifelse(sig, "*", ""), group = subgroup),
position = position_dodge(width = .9), vjust = -0.1, size = 30 / .pt) +
facet_wrap(~name, nrow=1, strip.position = "top") +
theme(text=element_text(size=14, face = "bold"),
axis.text.x = element_blank(), legend.position = "none",
axis.ticks.x = element_blank(), panel.border=element_blank(),
plot.margin = unit(c(0.25, 0.25, -0.1, 0.25), "inches"))
#if (is.null(ybreaks)) {ybreaks=seq(my_max, 0, by=-0.2)
#}else{ybreaks=ybreaks*-1}
ybreaks=rev(ybreaks)
#top, right, bottom, left
g2 <- d %>%
filter(ensembl_gene_id %in% sig_extra) %>%
filter(subgroup!="joint") %>%
mutate(dummy="dummy") %>%
ggplot(aes(x=dummy, y=abs(log2FC), fill=subgroup)) +
geom_bar(position = "dodge", stat = "identity") +
geom_errorbar(aes(ymin=ifelse(abs(log2FC)-lfcSE < 0, 0, abs(log2FC)-lfcSE),
ymax=abs(log2FC)+lfcSE), position="dodge") +
geom_label(position = position_dodge(width= 1), aes(label = " ", y = -0.05, fill = subgroup), size = 0.1) +
xlab("") + ylab("filler") +
theme_bw() +
#scale_fill_manual(values=c("#EEAF6A", "#CE7A1F", "#408EC6", "#1E2761")) +
scale_fill_manual(legend_title, values=cols) +
geom_text(aes(y = abs(log2FC)+lfcSE, label = ifelse(sig, "*", ""), group = subgroup),
position = position_dodge(width = .9), vjust = 1.1, size = 30 / .pt) +
facet_wrap(~name, nrow=1, strip.position = "bottom") +
scale_y_reverse(limits = c(max(ybreaks), -0.051), breaks = ybreaks, labels=relabel) +
#ylim(c(my_max, -0.051))
theme(text=element_text(size=14, face = "bold"),
axis.text.x = element_blank(), legend.position = "bottom",
axis.title.y=element_text(colour="white"),
strip.text.x = element_blank(), axis.ticks.x = element_blank(),
plot.margin = unit(c(-0.11, 0.25, 0.25, 0.25), "inches"), panel.border=element_blank())
return(grid.arrange(g1,g2,ncol=1))
}sig_extra = c(sig_joint$ensembl_gene_id)
g1 = amanda_barchart_subgroup(barchart_subgroup_df, sig_extra,
mytitle="Pre- vs Post-pairing individuals DEGs: Female-driven effect")
g2 = amanda_barchart_subgroup(barchart_sex_df, sig_extra,
mytitle="Pre- vs Post-pairing individuals DEGs: Female-driven effect",
legend_title="sex", cols=c("#bf083d", "#2b4599"))
ggsave(g1, file=paste0(output_dir, "figures/Fig5D.svg"), width=15, height=10)dir.create(paste0(output_dir,"figures/Fig5E_genePlots/"), recursive = TRUE, showWarnings = FALSE)possible <- bonding_df[rowSums(bonding_df[,c("padj_joint", "padj_WT", "padj_MUT", "padj_F", "padj_M",
"padj_WTF", "padj_WTM", "padj_MUTF", "padj_MUTM")] < 0.05,
na.rm=TRUE) > 0, "ensembl_gene_id" ]
sig_extra = setdiff(possible, sig_joint$ensembl_gene_id)
sig_extra = setdiff(sig_extra, "ENSMOCG00000010337")tmp = vole_annotation[vole_annotation$ensembl_gene_id %in% sig_extra, c("ensembl_gene_id", "external_gene_name")]
tmp[tmp$ensembl_gene_id == "ENSMOCG00000005084", "external_gene_name"] = "Hbb-bt (mm homolog)"
tmp[tmp$ensembl_gene_id == "ENSMOCG00000019704", "external_gene_name"] = "Sema3b (mm homolog)"
tmp[tmp$ensembl_gene_id == "ENSMOCG00000019711", "external_gene_name"] = "Mast4 (mm homolog)"
id = tmp$ensembl_gene_id
name=tmp$external_gene_name
e <- ddsnorm %>%
data.frame() %>%
filter(row.names(ddsnorm) %in% id) %>%
t() %>% data.frame() %>%
rownames_to_column() %>%
tidyr::pivot_longer(cols=-c(rowname), values_to='expr', names_to='gene') %>%
left_join(metadata[,c("SampleID", "tmp")], by=c("rowname"="SampleID")) %>%
left_join(tmp, by=c("gene"="ensembl_gene_id"))
e$tmp <- as.factor(e$tmp)
e$tmp <- factor(e$tmp, levels=c("WT_F_Pre-bond", "WT_F_Post-bond", "Mut6_F_Pre-bond", "Mut6_F_Post-bond",
"WT_M_Pre-bond", "WT_M_Post-bond", "Mut6_M_Pre-bond", "Mut6_M_Post-bond"))
e$external_gene_name <- as.factor(e$external_gene_name)
e$external_gene_name <- factor(e$external_gene_name, levels=name)
e$grouping = factor(gsub("_Pre-bond|_Post-bond", "", e$tmp),
levels=c("WT_F", "Mut6_F", "WT_M","Mut6_M"),
labels=c("WT F", "OXTR1-/- F", "WT M", "OXTR1-/- M"))
#pick = "Kdr"
#id = "ENSMOCG00000017085"
#pdf(file="~/Desktop/possible2.pdf", width = 8, height = 6)
#for (i in 1:nrow(tmp)){
# pick = tmp[i, "external_gene_name"]; id = tmp[i, "ensembl_gene_id"]
ofinterest = c("Fkbp5", "Adora2a", "Spred3", "Sema3b (mm homolog)", "Kdr", "Col4a1", "Col4a2")
for (pick in ofinterest){
id = tmp[tmp$external_gene_name == pick, "ensembl_gene_id"]
vect = bonding_df %>%
filter(ensembl_gene_id == id) %>%
select(c("padj_WTF", "padj_MUTF", "padj_WTM", "padj_MUTM")) %>%
as.numeric()
strip <- ggh4x::strip_themed(background_x = elem_list_rect(fill = ifelse(vect < 0.05, "lightgrey","white")))
g1 <- ggplot(e[e$external_gene_name == pick, ], aes(x=tmp, y=log2(expr), fill=tmp)) +
geom_boxplot() +
geom_jitter(color="black", size=2, alpha=0.5, width = 0.1) +
facet_grid2(.~grouping, scales = "free", switch = "x", space = "free_x", strip=strip) +
theme_minimal() + xlab("") +
ylab("log2 Normalized Gene Expression") +
ggtitle(pick) +
scale_x_discrete(labels = rep(c("pre", "post"),4)) +
scale_fill_manual(values=c("#087B8B","#E5A024", "#087B8B","#E5A024",
alpha(c("#087B8B","#E5A024", "#087B8B","#E5A024"), 0.3))) +
theme(text=element_text(size=14, face = "bold"),
strip.placement = "outside",
strip.background = element_rect(fill = "white"),
plot.title = element_text(hjust = 0.5),
legend.position = "none", axis.text.x = element_text(angle = 45, hjust = 1))
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig5E_genePlots/", pick, "_BoxPlot.svg"), width=10, height=7)
}ofinterest = c("Fkbp5", "Adora2a", "Spred3", "Sema3b (mm homolog)")
p1 = amanda_barchart_subgroup(barchart_subgroup_df,
tmp[tmp$external_gene_name %in% ofinterest, "ensembl_gene_id"],
mytitle="Sex-specific Genes")
ggsave(plot=p1, file=paste0(output_dir, "figures/Fig5E_genePlots/Fig5e_barplots.svg"), width=10, height=7)Gene-specific plots
ofinterest = c("Fkbp5", "Adora2a", "Spred3", "Sema3b (mm homolog)")
for (pick in ofinterest) {
id = tmp[tmp$external_gene_name == pick, "ensembl_gene_id"]
g2 <- amanda_barchart_subgroup(barchart_subgroup_df, c(id), mytitle=" ", ybreaks=c(0, 0.2, 0.4, 0.6))
ggsave(plot=g2, file=paste0(output_dir, "figures/Fig5E_genePlots/", pick, "_BarPlot.svg"),
width=5, height=6)
}
pick="Spred3"
g3 <- amanda_barchart_subgroup(barchart_sex_df, c("ENSMOCG00000017207"), mytitle=" ")
ggsave(plot=g3, file=paste0(output_dir, "figures/Fig5E_genePlots/", pick, "_BarPlot_Sex.svg"), width=5, height=6)ofinterest = c("Kdr", "Col4a1", "Col4a2")
p1 = amanda_barchart_subgroup(barchart_subgroup_df,
tmp[tmp$external_gene_name %in% ofinterest, "ensembl_gene_id"],
mytitle="Collagen Genes")
ggsave(plot=p1, file=paste0(output_dir, "figures/Fig5E_genePlots/Fig5e_collagen.svg"), width=10, height=7)
for (pick in ofinterest) {
id = tmp[tmp$external_gene_name == pick, "ensembl_gene_id"]
g2 <- amanda_barchart_subgroup(barchart_subgroup_df, c(id), mytitle=" ", ybreaks=c(0, 0.2, 0.4, 0.6, 0.8, 1.0))
ggsave(plot=g2, file=paste0(output_dir, "figures/Fig5E_genePlots/", pick, "_BarPlot.svg"),
width=5, height=6)
}
string_db <- STRINGdb$new( version="12.0", #current rn
species=9606, # human
score_threshold=200,
network_type="full",
input_directory="")
dgenes <- data.frame("genes" = sig_joint$hsapiens_homolog_associated_gene_name)
my_mapped <- string_db$map(dgenes, "genes", removeUnmappedRows = TRUE)
string_db$plot_network(my_mapped$STRING_id)
full.graph <- string_db$get_graph()
subgraph <- induced_subgraph(full.graph, my_mapped$STRING_id)
att = left_join(my_mapped, sig_joint[, c("hsapiens_homolog_associated_gene_name", "log2FoldChange", "padj")],
by=c("genes"="hsapiens_homolog_associated_gene_name"))
att = att[order(att$STRING_id, vertex_attr(subgraph)$name), ]
vertex_attr(subgraph)$label <- att$genes
col_fun = colorRamp2(c(-0.5, 0), hcl_palette = "Rocket")
vertex_attr(subgraph)$color <- col_fun(att$log2FoldChange)
#helpful code for development.
#c(bottom, left, top, right)
#c(5, 4, 4, 2)
#layout.matrix <- matrix(c(1,1, 1,2,3,4),ncol=2, nrow=3)
#layout(mat = layout.matrix, heights = c(1,1), widths = c(4,1))
#layout.show(3)
#pdf(file=paste0(output_dir, "figures/Supp5E_Network.pdf"), height = 10, width = 10)
par(mar=c(0,0,8,0))
#layout(matrix(1:2,ncol=2), width = c(4,1),height = c(1,1))
layout(matrix(c(1,1, 1,2,3,4),ncol=2, nrow=3), heights = c(1,1), widths = c(4,1))
set.seed(90) #10 okay too
test.layout <- layout_(subgraph, with_dh(weight.edge.lengths = edge_density(subgraph)/1000))
plot(subgraph, layout = test.layout, edge.curved = 0,
vertex.size=25, ylim=c(-1, 1), edge.width=4,
vertex.label.color="white", vertex.label.cex=1, vertex.label.font = 2)
mtext(string_db$get_summary(my_mapped$STRING_id, 200), cex = 1)
plot.new()
par(mar = c(0, 0, 2, 0))
legend_image <- as.raster(matrix(col_fun(seq(-0.5, 0, by=0.05)), ncol=1))
plot(c(0,2),c(0,1),type = 'n', axes = F,xlab = '', ylab = '', main = 'log2 Fold-change')
text(x=1.5, y = seq(0,1,l=6), labels = seq(0, 0.5, by = 0.1) * -1)
rasterImage(legend_image, 0, 0, 1,1)
#dev.off()
write.csv(sig_joint, file=paste0(output_dir, "Bonding_DEX.csv"))Q2: What is the mutation effect?
dds <- DESeqDataSetFromMatrix(countData = counts(set3), colData = pData(set3), design = ~ W_1 + species)
dds <- collapseReplicates(dds, groupby = dds$SampleID)
dds <- DESeq(dds)
ddsnorm_all <- counts(dds, normalized=TRUE)res_joint = lfcShrink(dds, type="ashr", contrast=list(c("species_Mut6_vs_WT")), quiet = TRUE)
mydf_all <- res_joint %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
left_join(vole_annotation, by="ensembl_gene_id")
genotype_df <- data.frame("ensembl_gene_id" = rownames(res_joint),
"log2FC_joint" = res_joint$log2FoldChange,
"padj_joint"= res_joint$padj)Now repeat in a sex-specific way
pData(set3)$group <- paste0(pData(set3)$species, "_", pData(set3)$Sex)
pData(set3)$group <- as.factor(pData(set3)$group)
pData(set3)[,"group"] <- relevel(pData(set3)[,"group"], ref = "WT_F")
dds <- DESeqDataSetFromMatrix(countData = counts(set3), colData = pData(set3), design = ~ W_1 + group)
dds <- collapseReplicates(dds, groupby = dds$SampleID)
dds <- DESeq(dds)
ddsnorm_sex <- counts(dds, normalized=TRUE)res = lfcShrink(dds, type="ashr", contrast=c("group", "Mut6_F", "WT_F"), quiet = TRUE)
mydf_F <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
left_join(vole_annotation, by="ensembl_gene_id")
genotype_df$log2FC_F <- res$log2FoldChange; genotype_df$padj_F <- res$log2FoldChange
res = lfcShrink(dds, type="ashr", contrast=c("group", "Mut6_M", "WT_M"), quiet = TRUE)
mydf_M <- res %>% as.data.frame() %>%
rownames_to_column(var="ensembl_gene_id") %>%
left_join(vole_annotation, by="ensembl_gene_id")
genotype_df$log2FC_M <- res$log2FoldChange; genotype_df$padj_M <- res$log2FoldChangegenotype_df <- left_join(genotype_df, vole_annotation, by="ensembl_gene_id")x = list(
"Joint" = genotype_df %>% filter(padj_joint < 0.05) %>% pull(ensembl_gene_id),
"Male" = genotype_df %>% filter(padj_M < 0.05) %>% pull(ensembl_gene_id),
"Female" = genotype_df %>% filter(padj_F < 0.05) %>% pull(ensembl_gene_id)
)
g1 <- ggVennDiagram(x, label_alpha = 0) +
scale_fill_gradient(low="blue",high = "yellow") +
scale_color_manual(values = c(rep("black",3))) +
theme(legend.position = "none") +
ggtitle("all DEX (padj < 0.05)")
x = list(
"Joint" = genotype_df %>% filter(padj_joint < 0.05, abs(log2FC_joint) > 0.25) %>% pull(ensembl_gene_id),
"Male" = genotype_df %>% filter(padj_M < 0.05, abs(log2FC_M) > 0.25) %>% pull(ensembl_gene_id),
"Female" = genotype_df %>% filter(padj_F < 0.05, abs(log2FC_F) > 0.25) %>% pull(ensembl_gene_id)
)
g2 <- ggVennDiagram(x, label_alpha = 0) +
scale_fill_gradient(low="blue",high = "yellow") +
scale_color_manual(values = c(rep("black",3))) +
theme(legend.position = "none") +
ggtitle("abs(log2FC) > 0.25")grid.arrange(g1,g2, ncol=2)
We can already see there are a lot of genes with small log2FCs
genotype_df$sig <- "neither"
genotype_df[genotype_df$ensembl_gene_id %in% intersect(x$Joint, x$Female), "sig"] <- "both"
genotype_df[genotype_df$ensembl_gene_id %in% setdiff(x$Joint, x$Female), "sig"] <- "joint"
genotype_df[genotype_df$ensembl_gene_id %in% setdiff(x$Female, x$Joint), "sig"] <- "female"
genotype_df$sig <- as.factor(genotype_df$sig)
genotype_df$sig <- factor(genotype_df$sig, levels = c("both", "joint", "female", "neither"))
tolabel <- genotype_df %>% filter(abs(log2FC_F) > 2 | abs(log2FC_joint) > 4)
tolabel$name <- ifelse(tolabel$external_gene_name == "", tolabel$ensembl_gene_id, tolabel$external_gene_name)
g1 <- ggplot(genotype_df, aes(x=abs(log2FC_joint), y=abs(log2FC_F), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
scale_color_manual(values=c("darkgreen", "#E69F00", "#56B4E9", "#DDDDDD")) +
theme(legend.position = "none") + ggtitle("Females") +
ggrepel::geom_text_repel(data=tolabel, aes(label=name), show.legend = F, size=2)
g2 <- ggplot(genotype_df, aes(x=abs(log2FC_joint), y=abs(log2FC_F), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
xlim(c(0,2)) + ylim(c(0,2)) + ggtitle("Femles: zoomed in") +
scale_color_manual(values=c("darkgreen", "#E69F00", "#56B4E9", "#DDDDDD"),
name = "significance @ \np < 0.05\nabs(log2FC) > 0.25")
grid.arrange(g1, g2,ncol=2)
genotype_df$sig <- "neither"
genotype_df[genotype_df$ensembl_gene_id %in% intersect(x$Joint, x$Male), "sig"] <- "both"
genotype_df[genotype_df$ensembl_gene_id %in% setdiff(x$Joint, x$Male), "sig"] <- "joint"
genotype_df[genotype_df$ensembl_gene_id %in% setdiff(x$Male, x$Joint), "sig"] <- "male"
genotype_df$sig <- as.factor(genotype_df$sig)
genotype_df$sig <- factor(genotype_df$sig, levels = c("both", "joint", "male", "neither"))
tolabel <- genotype_df %>% filter(abs(log2FC_M) > 2 | abs(log2FC_joint) > 4)
tolabel$name <- ifelse(tolabel$external_gene_name == "", tolabel$ensembl_gene_id, tolabel$external_gene_name)
g1 <- ggplot(genotype_df, aes(x=abs(log2FC_joint), y=abs(log2FC_M), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
scale_color_manual(values=c("darkgreen", "#E69F00", "#56B4E9", "#DDDDDD")) +
theme(legend.position = "none") + ggtitle("Males")+
ggrepel::geom_text_repel(data=tolabel, aes(label=name), show.legend = F, size=2)
g2 <- ggplot(genotype_df, aes(x=abs(log2FC_joint), y=abs(log2FC_M), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
xlim(c(0,2)) + ylim(c(0,2)) + ggtitle("Males: zoomed in") +
scale_color_manual(values=c("darkgreen", "#E69F00", "#56B4E9", "#DDDDDD"),
name = "significance @ \np < 0.05\nabs(log2FC) > 0.25")
grid.arrange(g1, g2,ncol=2)
genotype_df$sig <- "neither"
genotype_df[genotype_df$ensembl_gene_id %in% intersect(x$Female, x$Male), "sig"] <- "both"
genotype_df[genotype_df$ensembl_gene_id %in% setdiff(x$Female, x$Male), "sig"] <- "female"
genotype_df[genotype_df$ensembl_gene_id %in% setdiff(x$Male, x$Female), "sig"] <- "male"
genotype_df$sig <- as.factor(genotype_df$sig)
genotype_df$sig <- factor(genotype_df$sig, levels = c("both", "male", "female", "neither"))
tolabel <- genotype_df %>% filter(abs(log2FC_M) > 2 | abs(log2FC_F) > 2)
tolabel$name <- ifelse(tolabel$external_gene_name == "", tolabel$ensembl_gene_id, tolabel$external_gene_name)
g1 <- ggplot(genotype_df, aes(x=abs(log2FC_M), y=abs(log2FC_F), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
scale_color_manual(values=c("darkgreen", "#E69F00", "#56B4E9", "#DDDDDD")) +
theme(legend.position = "none") + ggtitle("Female FC compared to male") +
ggrepel::geom_text_repel(data=tolabel, aes(label=name), show.legend = F, size=2)
g2 <- ggplot(genotype_df, aes(x=abs(log2FC_M), y=abs(log2FC_F), color=sig)) +
geom_point() + theme_bw() +
geom_abline(slope=1, intercept=0, color="black", linetype="dashed", linewidth=0.5) +
xlim(c(0,2)) + ylim(c(0,2)) + ggtitle("zoomed in") +
scale_color_manual(values=c("darkgreen", "#E69F00", "#56B4E9", "#DDDDDD"),
name = "significance @ \np < 0.05\nabs(log2FC) > 0.25")
grid.arrange(g1, g2,ncol=2)
maybesexspecific <- genotype_df %>%
filter(sig %ni% c("both", "neither")) %>%
filter(abs(log2FC_M) > 1 | abs(log2FC_F) > 1 )print("My take-away is that the 'joint' list where we combine sexes when looking at OXTR -/- vs WT individuals is the most representitive. One piece of reasoning for that is that the effect sizes for hits in the F and M separate analyses mostly get larger in the joint analysis, showing they're working together.")## [1] "My take-away is that the 'joint' list where we combine sexes when looking at OXTR -/- vs WT individuals is the most representitive. One piece of reasoning for that is that the effect sizes for hits in the F and M separate analyses mostly get larger in the joint analysis, showing they're working together."sig <- mydf_all %>% filter(padj < 0.05 & abs(log2FoldChange) > 0.25) %>% arrange(padj)DEX Table
cat("Number of DEX genes:", nrow(sig))## Number of DEX genes: 1014sig %>%
kbl() %>%
kable_styling(bootstrap_options = c("striped", "hover", "condensed")) %>%
scroll_box(width = "800px", height = "400px")| ensembl_gene_id | baseMean | log2FoldChange | lfcSE | pvalue | padj | entrezgene_ids | external_gene_names | gene_biotype | entrezgene_id | external_gene_name | mmusculus_homolog_ensembl_gene | mmusculus_homolog_associated_gene_name | mmusculus_homolog_orthology_type | mmusculus_homolog_perc_id | hsapiens_homolog_ensembl_gene | hsapiens_homolog_associated_gene_name | hsapiens_homolog_orthology_type | hsapiens_homolog_perc_id | mmusculus_homolog_ensembl_genes | mmusculus_homolog_associated_gene_names | mmusculus_homolog_perc_ids | hsapiens_homolog_ensembl_genes | hsapiens_homolog_associated_gene_names | hsapiens_homolog_perc_ids | mmusculus_entrezgene_ids | mmusculus_entrezgene_id | hsapiens_entrezgene_ids | hsapiens_entrezgene_id |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ENSMOCG00000020069 | 2097.701405 | 0.4140867 | 0.0345112 | 0.0000000 | 0.0000000 | 102002880 | Slc2a3 | protein_coding | 102002880 | Slc2a3 | ENSMUSG00000003153 | Slc2a3 | ortholog_one2one | 89.0244 | NA | NA | NA | NA | NA | NA | NA | 20527 | 20527 | NA | NA | |||
| ENSMOCG00000003348 | 2860.633861 | 0.3874493 | 0.0336620 | 0.0000000 | 0.0000000 | 102001679 | Kcna1 | protein_coding | 102001679 | Kcna1 | ENSMUSG00000047976 | Kcna1 | ortholog_one2one | 99.3939 | ENSG00000111262 | KCNA1 | ortholog_one2one | 98.1818 | NA | NA | NA | NA | NA | NA | 16485 | 16485 | 3736 | 3736 |
| ENSMOCG00000015206 | 1523.187882 | -0.8973053 | 0.0794175 | 0.0000000 | 0.0000000 | 101980084, 101997396 | , | protein_coding | 101980084 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | |||||||
| ENSMOCG00000008371 | 3000.823168 | 0.2892832 | 0.0273260 | 0.0000000 | 0.0000000 | 101988943 | Rgs8 | protein_coding | 101988943 | Rgs8 | ENSMUSG00000042671 | Rgs8 | ortholog_one2one | 98.8889 | ENSG00000135824 | RGS8 | ortholog_one2one | 99.4444 | NA | NA | NA | NA | NA | NA | 67792 | 67792 | 85397 | 85397 |
| ENSMOCG00000000158 | 2531.522755 | 0.4784067 | 0.0469117 | 0.0000000 | 0.0000000 | 101981468 | Cnksr2 | protein_coding | 101981468 | Cnksr2 | ENSMUSG00000025658 | Cnksr2 | ortholog_one2one | 98.2558 | ENSG00000149970 | CNKSR2 | ortholog_one2one | 98.3527 | NA | NA | NA | NA | NA | NA | 245684 | 245684 | 22866 | 22866 |
| ENSMOCG00000021159 | 197.933160 | 0.7024903 | 0.0711058 | 0.0000000 | 0.0000000 | 102000853 | Acvr1c | protein_coding | 102000853 | Acvr1c | ENSMUSG00000026834 | Acvr1c | ortholog_one2one | 97.7688 | ENSG00000123612 | ACVR1C | ortholog_one2one | 93.3063 | NA | NA | NA | NA | NA | NA | 269275 | 269275 | 130399 | 130399 |
| ENSMOCG00000001133 | 542.410241 | 0.3173673 | 0.0325954 | 0.0000000 | 0.0000000 | 101997868 | protein_coding | 101997868 | ENSMUSG00000065954 | Tacc1 | ortholog_one2one | 95.3678 | ENSG00000147526 | TACC1 | ortholog_one2one | 93.4605 | NA | NA | NA | NA | NA | NA | 320165 | 320165 | 6867 | 6867 | ||
| ENSMOCG00000016726 | 59.516152 | -1.4029891 | 0.1619847 | 0.0000000 | 0.0000000 | 101985773 | protein_coding | 101985773 | ENSMUSG00000027890 | Gstm4 | ortholog_one2many | 90.3670 | ENSG00000168765 | GSTM4 | ortholog_one2many | 86.6973 | NA | NA | NA | NA | NA | NA | 14865 | 14865 | 2948 | 2948 | ||
| ENSMOCG00000021662 | 794.292406 | 0.3150956 | 0.0352556 | 0.0000000 | 0.0000000 | 101983691 | Cnot6 | protein_coding | 101983691 | Cnot6 | ENSMUSG00000020362 | Cnot6 | ortholog_one2one | 99.8205 | ENSG00000113300 | CNOT6 | ortholog_one2one | 96.0503 | NA | NA | NA | NA | NA | NA | 104625 | 104625 | 57472 | 57472 |
| ENSMOCG00000013376 | 1189.465982 | 0.4084157 | 0.0469412 | 0.0000000 | 0.0000000 | 101990850 | Foxp1 | protein_coding | 101990850 | Foxp1 | ENSMUSG00000030067 | Foxp1 | ortholog_one2one | 98.5775 | ENSG00000114861 | FOXP1 | ortholog_one2one | 93.1721 | NA | NA | NA | NA | NA | NA | 108655 | 108655 | 27086 | 27086 |
| ENSMOCG00000016426 | 788.938103 | 0.3856812 | 0.0452057 | 0.0000000 | 0.0000000 | 101992032 | Cldn12 | protein_coding | 101992032 | Cldn12 | ENSMUSG00000046798 | Cldn12 | ortholog_one2one | 95.9016 | ENSG00000157224 | CLDN12 | ortholog_one2one | 92.2131 | NA | NA | NA | NA | NA | NA | 64945 | 64945 | 9069 | 9069 |
| ENSMOCG00000020648 | 3166.189953 | 0.3970656 | 0.0468603 | 0.0000000 | 0.0000000 | 101996670 | Cacna2d3 | protein_coding | 101996670 | Cacna2d3 | ENSMUSG00000021991 | Cacna2d3 | ortholog_one2one | 98.1668 | ENSG00000157445 | CACNA2D3 | ortholog_one2one | 97.3419 | NA | NA | NA | NA | NA | NA | 12294 | 12294 | 55799 | 55799 |
| ENSMOCG00000007666 | 224.597356 | -7.0533507 | 0.8051463 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | NA | ENSG00000111640 | GAPDH | ortholog_one2many | 92.4242 | NA | NA | NA | NA | NA | NA | NA | NA | 2597 | 2597 | |||||
| ENSMOCG00000000086 | 658.849706 | 0.4635763 | 0.0558037 | 0.0000000 | 0.0000000 | 101982834 | B3gnt2 | protein_coding | 101982834 | B3gnt2 | ENSMUSG00000051650 | B3gnt2 | ortholog_one2one | 94.2066 | ENSG00000170340 | B3GNT2 | ortholog_one2one | 88.6650 | NA | NA | NA | NA | NA | NA | 53625 | 53625 | 10678 | 10678 |
| ENSMOCG00000019076 | 683.095029 | 0.5771875 | 0.0684585 | 0.0000000 | 0.0000000 | 101981670 | Slc24a4 | protein_coding | 101981670 | Slc24a4 | ENSMUSG00000041771 | Slc24a4 | ortholog_one2one | 95.3526 | ENSG00000140090 | SLC24A4 | ortholog_one2one | 91.8269 | NA | NA | NA | NA | NA | NA | 238384 | 238384 | 123041 | 123041 |
| ENSMOCG00000003033 | 5099.226248 | 0.5314593 | 0.0650499 | 0.0000000 | 0.0000000 | 101995112 | Gucy1a1 | protein_coding | 101995112 | Gucy1a1 | ENSMUSG00000033910 | Gucy1a1 | ortholog_one2one | 95.9479 | ENSG00000164116 | GUCY1A1 | ortholog_one2one | 90.5933 | NA | NA | NA | NA | NA | NA | 60596 | 60596 | 2982 | 2982 |
| ENSMOCG00000013328 | 35.116817 | 1.0291907 | 0.1246013 | 0.0000000 | 0.0000000 | 101978947 | Lmcd1 | protein_coding | 101978947 | Lmcd1 | ENSMUSG00000057604 | Lmcd1 | ortholog_one2one | 97.2603 | ENSG00000071282 | LMCD1 | ortholog_one2one | 92.8767 | NA | NA | NA | NA | NA | NA | 30937 | 30937 | 29995 | 29995 |
| ENSMOCG00000010948 | 1137.575118 | -0.6724049 | 0.0807527 | 0.0000000 | 0.0000000 | 101997988 | Apod | protein_coding | 101997988 | Apod | ENSMUSG00000022548 | Apod | ortholog_one2one | 85.7143 | ENSG00000189058 | APOD | ortholog_one2one | 77.7778 | NA | NA | NA | NA | NA | NA | 11815 | 11815 | 347 | 347 |
| ENSMOCG00000010597 | 31.970239 | 2.0923996 | 0.2650668 | 0.0000000 | 0.0000000 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000011387 | 96.403126 | -0.9174275 | 0.1112531 | 0.0000000 | 0.0000000 | 101984893 | Nrip2 | protein_coding | 101984893 | Nrip2 | ENSMUSG00000001520 | Nrip2 | ortholog_one2one | 76.7717 | ENSG00000053702 | NRIP2 | ortholog_one2one | 63.7795 | NA | NA | NA | NA | NA | NA | 60345 | 60345 | 83714 | 83714 |
| ENSMOCG00000008886 | 640.396515 | 0.3254066 | 0.0398659 | 0.0000000 | 0.0000000 | 101996275 | Rgs7bp | protein_coding | 101996275 | Rgs7bp | ENSMUSG00000021719 | Rgs7bp | ortholog_one2one | 95.7198 | ENSG00000186479 | RGS7BP | ortholog_one2one | 94.1634 | NA | NA | NA | NA | NA | NA | 52882 | 52882 | 401190 | 401190 |
| ENSMOCG00000001866 | 594.076993 | 0.4094822 | 0.0516314 | 0.0000000 | 0.0000000 | 101989153 | Filip1 | protein_coding | 101989153 | Filip1 | ENSMUSG00000034898 | Filip1 | ortholog_one2one | 96.2871 | ENSG00000118407 | FILIP1 | ortholog_one2one | 93.7294 | NA | NA | NA | NA | NA | NA | 70598 | 70598 | 27145 | 27145 |
| ENSMOCG00000017062 | 63.946282 | -0.8733750 | 0.1062878 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | NA | ENSG00000099256 | PRTFDC1 | ortholog_one2one | 87.6712 | NA | NA | NA | NA | NA | NA | NA | NA | 56952 | 56952 | |||||
| ENSMOCG00000022542 | 515.159233 | 0.4836214 | 0.0614758 | 0.0000000 | 0.0000000 | 101990489 | Dclk3 | protein_coding | 101990489 | Dclk3 | ENSMUSG00000032500 | Dclk3 | ortholog_one2one | 83.7469 | ENSG00000163673 | DCLK3 | ortholog_one2one | 77.5434 | NA | NA | NA | NA | NA | NA | 245038 | 245038 | 85443 | 85443 |
| ENSMOCG00000021524 | 749.330459 | 0.4047501 | 0.0512712 | 0.0000000 | 0.0000000 | 101996041 | Sv2c | protein_coding | 101996041 | Sv2c | ENSMUSG00000051111 | Sv2c | ortholog_one2one | 98.8996 | ENSG00000122012 | SV2C | ortholog_one2one | 96.6988 | NA | NA | NA | NA | NA | NA | 75209 | 75209 | 22987 | 22987 |
| ENSMOCG00000014090 | 6464.719368 | 0.3821527 | 0.0483187 | 0.0000000 | 0.0000000 | 102002707 | Rasd2 | protein_coding | 102002707 | Rasd2 | ENSMUSG00000034472 | Rasd2 | ortholog_one2one | 98.8722 | ENSG00000100302 | RASD2 | ortholog_one2one | 94.7368 | NA | NA | NA | NA | NA | NA | 75141 | 75141 | 23551 | 23551 |
| ENSMOCG00000006480 | 30.454035 | 1.3717797 | 0.1793496 | 0.0000000 | 0.0000000 | 101988972 | Clec9a | protein_coding | 101988972 | Clec9a | ENSMUSG00000046080 | Clec9a | ortholog_one2one | 68.4647 | ENSG00000197992 | CLEC9A | ortholog_one2one | 63.4855 | NA | NA | NA | NA | NA | NA | 232414 | 232414 | 283420 | 283420 |
| ENSMOCG00000018891 | 294.737701 | -0.9741268 | 0.1207878 | 0.0000000 | 0.0000000 | 101981359 | Ercc6 | protein_coding | 101981359 | Ercc6 | ENSMUSG00000054051 | Ercc6 | ortholog_one2one | 85.1927 | ENSG00000225830 | ERCC6 | ortholog_one2one | 79.7160 | NA | NA | NA | NA | NA | NA | 319955 | 319955 | 2074 | 2074 |
| ENSMOCG00000015653 | 77.191591 | -1.8337712 | 0.2383059 | 0.0000000 | 0.0000000 | 101989760 | Amhr2 | protein_coding | 101989760 | Amhr2 | ENSMUSG00000023047 | Amhr2 | ortholog_one2one | 89.2665 | ENSG00000135409 | AMHR2 | ortholog_one2one | 77.6386 | NA | NA | NA | NA | NA | NA | 110542 | 110542 | 269 | 269 |
| ENSMOCG00000019503 | 51.866228 | -1.0938015 | 0.1386929 | 0.0000000 | 0.0000000 | 101981407 | Arntl2 | protein_coding | 101981407 | Arntl2 | ENSMUSG00000040187 | Arntl2 | ortholog_one2one | 75.0000 | ENSG00000029153 | BMAL2 | ortholog_one2one | 68.2143 | NA | NA | NA | NA | NA | NA | 272322 | 272322 | 56938 | 56938 |
| ENSMOCG00000009834 | 1158.050811 | 0.4202401 | 0.0540350 | 0.0000000 | 0.0000000 | 101984360 | Coro7 | protein_coding | 101984360 | Coro7 | ENSMUSG00000039637 | Coro7 | ortholog_one2one | 85.5219 | ENSG00000262246 | CORO7 | ortholog_one2one | 81.4815 | NA | NA | NA | NA | NA | NA | 78885 | 78885 | 79585 | 79585 |
| ENSMOCG00000007360 | 207.832637 | 0.5823996 | 0.0733120 | 0.0000000 | 0.0000000 | 101982896 | Gpr52 | protein_coding | 101982896 | Gpr52 | ENSMUSG00000118401 | Gpr52 | ortholog_one2one | 97.7839 | ENSG00000203737 | GPR52 | ortholog_one2one | 96.1219 | NA | NA | NA | NA | NA | NA | 620246 | 620246 | 9293 | 9293 |
| ENSMOCG00000017183 | 3695.744863 | 0.2527016 | 0.0310925 | 0.0000000 | 0.0000000 | 101986453 | Sec14l1 | protein_coding | 101986453 | Sec14l1 | ENSMUSG00000020823 | Sec14l1 | ortholog_one2one | 96.8056 | ENSG00000129657 | SEC14L1 | ortholog_one2one | 94.7222 | NA | NA | NA | NA | NA | NA | 74136 | 74136 | 6397 | 6397 |
| ENSMOCG00000001284 | 40.506949 | -1.4852446 | 0.1979234 | 0.0000000 | 0.0000000 | 101983324 | Lgr6 | protein_coding | 101983324 | Lgr6 | ENSMUSG00000042793 | Lgr6 | ortholog_one2one | 94.9328 | ENSG00000133067 | LGR6 | ortholog_one2one | 89.1417 | NA | NA | NA | NA | NA | NA | 329252 | 329252 | 59352 | 59352 |
| ENSMOCG00000004288 | 844.772742 | 0.3382995 | 0.0429668 | 0.0000000 | 0.0000000 | 101984333 | Cacna1c | protein_coding | 101984333 | Cacna1c | ENSMUSG00000051331 | Cacna1c | ortholog_one2one | 94.8952 | ENSG00000151067 | CACNA1C | ortholog_one2one | 91.5223 | NA | NA | NA | NA | NA | NA | 12288 | 12288 | 775, 100874369 | 775 |
| ENSMOCG00000001332 | 424.353029 | 0.5795174 | 0.0742364 | 0.0000000 | 0.0000000 | 101987518 | Gprin3 | protein_coding | 101987518 | Gprin3 | ENSMUSG00000045441 | Gprin3 | ortholog_one2one | 74.3046 | ENSG00000185477 | GPRIN3 | ortholog_one2one | 61.0596 | NA | NA | NA | NA | NA | NA | 243385 | 243385 | 285513 | 285513 |
| ENSMOCG00000019256 | 665.219742 | -0.4251831 | 0.0556794 | 0.0000000 | 0.0000000 | 101998996 | Fgfr1 | protein_coding | 101998996 | Fgfr1 | ENSMUSG00000031565 | Fgfr1 | ortholog_one2one | 94.8843 | ENSG00000077782 | FGFR1 | ortholog_one2one | 94.8843 | NA | NA | NA | NA | NA | NA | 14182 | 14182 | 2260 | 2260 |
| ENSMOCG00000022995 | 945.388841 | 0.4141616 | 0.0545893 | 0.0000000 | 0.0000000 | 101988567 | Fktn | protein_coding | 101988567 | Fktn | ENSMUSG00000028414 | Fktn | ortholog_one2one | 93.0586 | ENSG00000106692 | FKTN | ortholog_one2one | 89.5879 | NA | NA | NA | NA | NA | NA | 246179 | 246179 | 2218 | 2218 |
| ENSMOCG00000012513 | 8622.350188 | 0.3497098 | 0.0454142 | 0.0000000 | 0.0000000 | 101989578 | Atp2b1 | protein_coding | 101989578 | Atp2b1 | ENSMUSG00000019943 | Atp2b1 | ortholog_one2one | 96.6614 | ENSG00000070961 | ATP2B1 | ortholog_one2one | 96.2639 | NA | NA | NA | NA | NA | NA | 67972 | 67972 | 490 | 490 |
| ENSMOCG00000002394 | 502.226995 | -0.3202072 | 0.0411394 | 0.0000000 | 0.0000000 | 102001026 | protein_coding | 102001026 | ENSMUSG00000025702 | Marchf8 | ortholog_one2one | 95.8333 | ENSG00000165406 | MARCHF8 | ortholog_one2one | 89.9306 | NA | NA | NA | NA | NA | NA | 71779 | 71779 | 220972 | 220972 | ||
| ENSMOCG00000002047 | 1848.708774 | 0.2953445 | 0.0376014 | 0.0000000 | 0.0000000 | 101986794 | Plcb1 | protein_coding | 101986794 | Plcb1 | ENSMUSG00000051177 | Plcb1 | ortholog_one2one | 98.1387 | ENSG00000182621 | PLCB1 | ortholog_one2one | 96.7851 | NA | NA | NA | NA | NA | NA | 18795 | 18795 | 23236 | 23236 |
| ENSMOCG00000018682 | 1065.591044 | 0.3347638 | 0.0434803 | 0.0000000 | 0.0000000 | 101983615 | Arhgap26 | protein_coding | 101983615 | Arhgap26 | ENSMUSG00000036452 | Arhgap26 | ortholog_one2one | 97.5369 | ENSG00000145819 | ARHGAP26 | ortholog_one2one | 90.1478 | NA | NA | NA | NA | NA | NA | 71302 | 71302 | 23092 | 23092 |
| ENSMOCG00000005546 | 2103.366421 | 0.3462275 | 0.0455692 | 0.0000000 | 0.0000000 | 101983571 | Dgkb | protein_coding | 101983571 | Dgkb | ENSMUSG00000036095 | Dgkb | ortholog_one2one | 98.7421 | ENSG00000136267 | DGKB | ortholog_one2one | 96.8553 | NA | NA | NA | NA | NA | NA | 217480 | 217480 | 1607 | 1607 |
| ENSMOCG00000020447 | 412.356041 | -0.4758640 | 0.0642899 | 0.0000000 | 0.0000000 | 101985565 | Fbxw8 | protein_coding | 101985565 | Fbxw8 | ENSMUSG00000032867 | Fbxw8 | ortholog_one2one | 91.7785 | ENSG00000174989 | FBXW8 | ortholog_one2one | 82.0470 | NA | NA | NA | NA | NA | NA | 231672 | 231672 | 26259 | 26259 |
| ENSMOCG00000020211 | 66.640010 | -0.7199729 | 0.0926688 | 0.0000000 | 0.0000000 | 101981758 | Prr5l | protein_coding | 101981758 | Prr5l | ENSMUSG00000032841 | Prr5l | ortholog_one2one | 95.6757 | ENSG00000135362 | PRR5L | ortholog_one2one | 89.7297 | NA | NA | NA | NA | NA | NA | 72446 | 72446 | 79899 | 79899 |
| ENSMOCG00000019383 | 192.598718 | 0.6209579 | 0.0814343 | 0.0000000 | 0.0000000 | 101983467 | Thsd7a | protein_coding | 101983467 | Thsd7a | ENSMUSG00000032625 | Thsd7a | ortholog_one2one | 92.8919 | ENSG00000005108 | THSD7A | ortholog_one2one | 90.5832 | NA | NA | NA | NA | NA | NA | 330267 | 330267 | 221981 | 221981 |
| ENSMOCG00000014756 | 601.639972 | 0.3907131 | 0.0529875 | 0.0000000 | 0.0000000 | 101978874 | Kcnma1 | protein_coding | 101978874 | Kcnma1 | ENSMUSG00000063142 | Kcnma1 | ortholog_one2one | 99.5146 | ENSG00000156113 | KCNMA1 | ortholog_one2one | 98.0583 | NA | NA | NA | NA | NA | NA | 16531 | 16531 | 3778 | 3778 |
| ENSMOCG00000014789 | 485.554670 | -0.5862553 | 0.0784098 | 0.0000000 | 0.0000000 | 101980985 | Kndc1 | protein_coding | 101980985 | Kndc1 | ENSMUSG00000066129 | Kndc1 | ortholog_one2one | 90.9301 | ENSG00000171798 | KNDC1 | ortholog_one2one | 74.8122 | NA | NA | NA | NA | NA | NA | 76484 | 76484 | 85442 | 85442 |
| ENSMOCG00000016012 | 1859.366196 | 0.4758156 | 0.0652844 | 0.0000000 | 0.0000000 | 102001574 | Necab1 | protein_coding | 102001574 | Necab1 | ENSMUSG00000040536 | Necab1 | ortholog_one2one | 97.7273 | ENSG00000123119 | NECAB1 | ortholog_one2one | 95.1705 | NA | NA | NA | NA | NA | NA | 69352 | 69352 | 64168 | 64168 |
| ENSMOCG00000004855 | 134.250608 | -0.5371513 | 0.0730740 | 0.0000000 | 0.0000000 | 101984698 | Ogg1 | protein_coding | 101984698 | Ogg1 | ENSMUSG00000030271 | Ogg1 | ortholog_one2one | 89.8551 | ENSG00000114026 | OGG1 | ortholog_one2one | 83.1884 | NA | NA | NA | NA | NA | NA | 18294 | 18294 | 4968 | 4968 |
| ENSMOCG00000002386 | 1211.512740 | -0.2986041 | 0.0395601 | 0.0000000 | 0.0000000 | 101982263 | Gstm7 | protein_coding | 101982263 | Gstm7 | ENSMUSG00000004035 | Gstm7 | ortholog_one2one | 94.0367 | ENSG00000213366 | GSTM2 | ortholog_one2one | 85.3211 | NA | NA | NA | NA | NA | NA | 68312 | 68312 | 2946 | 2946 |
| ENSMOCG00000016596 | 4239.876410 | 0.5157452 | 0.0710883 | 0.0000000 | 0.0000000 | 101990937 | Pde10a | protein_coding | 101990937 | Pde10a | ENSMUSG00000023868 | Pde10a | ortholog_one2one | 94.5844 | ENSG00000112541 | PDE10A | ortholog_one2one | 95.5919 | NA | NA | NA | NA | NA | NA | 23984 | 23984 | 10846, 90632 | 10846 |
| ENSMOCG00000011761 | 2364.084689 | 0.2621403 | 0.0344589 | 0.0000000 | 0.0000000 | 101992922 | Scn2a | protein_coding | 101992922 | Scn2a | ENSMUSG00000075318 | Scn2a | ortholog_one2one | 99.3021 | ENSG00000136531 | SCN2A | ortholog_one2one | 97.7567 | NA | NA | NA | NA | NA | NA | 110876 | 110876 | 6326 | 6326 |
| ENSMOCG00000015620 | 1432.098418 | 0.2753751 | 0.0363970 | 0.0000000 | 0.0000000 | NA | Nedd4l | protein_coding | NA | Nedd4l | ENSMUSG00000024589 | Nedd4l | ortholog_one2one | 99.0232 | ENSG00000049759 | NEDD4L | ortholog_one2one | 97.4359 | NA | NA | NA | NA | NA | NA | 83814 | 83814 | 23327 | 23327 |
| ENSMOCG00000017442 | 381.049737 | 0.4213840 | 0.0584897 | 0.0000000 | 0.0000000 | 101993199 | Lrrc61 | protein_coding | 101993199 | Lrrc61 | ENSMUSG00000073096 | Lrrc61 | ortholog_one2one | 91.8919 | ENSG00000127399 | LRRC61 | ortholog_one2one | 86.4865 | NA | NA | NA | NA | NA | NA | 243371 | 243371 | 65999 | 65999 |
| ENSMOCG00000018862 | 152.302331 | -0.8712576 | 0.1159412 | 0.0000000 | 0.0000000 | 101982072 | Syt2 | protein_coding | 101982072 | Syt2 | ENSMUSG00000026452 | Syt2 | ortholog_one2one | 98.8067 | ENSG00000143858 | SYT2 | ortholog_one2one | 97.8520 | NA | NA | NA | NA | NA | NA | 20980 | 20980 | 127833 | 127833 |
| ENSMOCG00000011049 | 2482.088274 | -0.2926714 | 0.0390463 | 0.0000000 | 0.0000000 | 101991839 | Chd5 | protein_coding | 101991839 | Chd5 | ENSMUSG00000005045 | Chd5 | ortholog_one2one | 85.8383 | ENSG00000116254 | CHD5 | ortholog_one2one | 83.5541 | NA | NA | NA | NA | NA | NA | 269610 | 269610 | 26038 | 26038 |
| ENSMOCG00000002174 | 15.573979 | -2.5569454 | 0.3649044 | 0.0000000 | 0.0000000 | 101991527 | protein_coding | 101991527 | ENSMUSG00000089728 | Clec2f | ortholog_one2many | 47.6415 | NA | NA | NA | NA | NA | NA | NA | 435921 | 435921 | NA | NA | |||||
| ENSMOCG00000002544 | 279.437563 | -0.5215956 | 0.0724597 | 0.0000000 | 0.0000000 | 101993749 | Agpat4 | protein_coding | 101993749 | Agpat4 | ENSMUSG00000023827 | Agpat4 | ortholog_one2one | 97.0900 | ENSG00000026652 | AGPAT4 | ortholog_one2one | 85.9788 | NA | NA | NA | NA | NA | NA | 68262 | 68262 | 56895 | 56895 |
| ENSMOCG00000002117 | 27.255270 | -3.0281544 | 0.4286041 | 0.0000000 | 0.0000000 | 101988975 | Cdhr18 | protein_coding | 101988975 | Cdhr18 | ENSMUSG00000084902 | Cdhr18 | ortholog_one2one | 81.3225 | NA | NA | NA | NA | NA | NA | NA | 238939 | 238939 | NA | NA | |||
| ENSMOCG00000013653 | 195.284403 | 0.6294575 | 0.0854575 | 0.0000000 | 0.0000000 | 101996847 | Vav3 | protein_coding | 101996847 | Vav3 | ENSMUSG00000033721 | Vav3 | ortholog_one2one | 96.8123 | ENSG00000134215 | VAV3 | ortholog_one2one | 95.8678 | NA | NA | NA | NA | NA | NA | 57257 | 57257 | 10451 | 10451 |
| ENSMOCG00000009231 | 649.213799 | 0.3941447 | 0.0551187 | 0.0000000 | 0.0000000 | 101992989 | Map4k3 | protein_coding | 101992989 | Map4k3 | ENSMUSG00000024242 | Map4k3 | ortholog_one2one | 94.3694 | ENSG00000011566 | MAP4K3 | ortholog_one2one | 92.7928 | NA | NA | NA | NA | NA | NA | 225028 | 225028 | 8491 | 8491 |
| ENSMOCG00000017386 | 254.884379 | -0.4856319 | 0.0684073 | 0.0000000 | 0.0000000 | 101979680 | Slco3a1 | protein_coding | 101979680 | Slco3a1 | ENSMUSG00000025790 | Slco3a1 | ortholog_one2one | 99.1549 | ENSG00000176463 | SLCO3A1 | ortholog_one2one | 98.0282 | NA | NA | NA | NA | NA | NA | 108116 | 108116 | 28232 | 28232 |
| ENSMOCG00000012764 | 246.464305 | -0.6150195 | 0.0841938 | 0.0000000 | 0.0000000 | 101992830 | Cdk18 | protein_coding | 101992830 | Cdk18 | ENSMUSG00000026437 | Cdk18 | ortholog_one2one | 96.1625 | ENSG00000117266 | CDK18 | ortholog_one2one | 91.8736 | NA | NA | NA | NA | NA | NA | 18557 | 18557 | 5129 | 5129 |
| ENSMOCG00000011784 | 121.030420 | -0.5582832 | 0.0781486 | 0.0000000 | 0.0000000 | 101996174 | Ebf4 | protein_coding | 101996174 | Ebf4 | ENSMUSG00000053552 | Ebf4 | ortholog_one2one | 97.0000 | ENSG00000088881 | EBF4 | ortholog_one2one | 93.6667 | NA | NA | NA | NA | NA | NA | 228598 | 228598 | 57593 | 57593 |
| ENSMOCG00000007800 | 17.993204 | 2.0619817 | 0.2992539 | 0.0000000 | 0.0000000 | 101988809 | Zcwpw1 | protein_coding | 101988809 | Zcwpw1 | ENSMUSG00000037108 | Zcwpw1 | ortholog_one2one | 77.6886 | ENSG00000078487 | ZCWPW1 | ortholog_one2one | 63.4029 | NA | NA | NA | NA | NA | NA | 381678 | 381678 | 55063 | 55063 |
| ENSMOCG00000015343 | 34.216210 | -1.5721926 | 0.2329846 | 0.0000000 | 0.0000000 | 101992761 | Blnk | protein_coding | 101992761 | Blnk | ENSMUSG00000061132 | Blnk | ortholog_one2one | 91.6849 | ENSG00000095585 | BLNK | ortholog_one2one | 84.6827 | NA | NA | NA | NA | NA | NA | 17060 | 17060 | 29760 | 29760 |
| ENSMOCG00000022111 | 152.724985 | 0.8564113 | 0.1173334 | 0.0000000 | 0.0000000 | NA | Gm11992 | protein_coding | NA | Gm11992 | ENSMUSG00000040978 | Gm11992 | ortholog_one2one | 85.5172 | ENSG00000164746 | C7orf57 | ortholog_one2one | 73.7931 | NA | NA | NA | NA | NA | NA | 626870 | 626870 | 136288 | 136288 |
| ENSMOCG00000000493 | 414.719485 | 0.3363962 | 0.0472306 | 0.0000000 | 0.0000000 | 101990432 | Utp15 | protein_coding | 101990432 | Utp15 | ENSMUSG00000041747 | Utp15 | ortholog_one2one | 91.8561 | ENSG00000164338 | UTP15 | ortholog_one2one | 88.6364 | NA | NA | NA | NA | NA | NA | 105372 | 105372 | 84135 | 84135 |
| ENSMOCG00000001527 | 333.451391 | 0.3645749 | 0.0523147 | 0.0000000 | 0.0000000 | 101996890 | Atxn1 | protein_coding | 101996890 | Atxn1 | ENSMUSG00000046876 | Atxn1 | ortholog_one2one | 96.4602 | ENSG00000124788 | ATXN1 | ortholog_one2one | 90.8976 | NA | NA | NA | NA | NA | NA | 20238 | 20238 | 6310 | 6310 |
| ENSMOCG00000020893 | 1860.818750 | 0.3834136 | 0.0555641 | 0.0000000 | 0.0000000 | 101984407 | Rasgrp1 | protein_coding | 101984407 | Rasgrp1 | ENSMUSG00000027347 | Rasgrp1 | ortholog_one2one | 96.4824 | ENSG00000172575 | RASGRP1 | ortholog_one2one | 91.7923 | NA | NA | NA | NA | NA | NA | 19419 | 19419 | 10125 | 10125 |
| ENSMOCG00000016694 | 205.650401 | -0.5519380 | 0.0798061 | 0.0000000 | 0.0000000 | 101983499 | Oxnad1 | protein_coding | 101983499 | Oxnad1 | ENSMUSG00000021906 | Oxnad1 | ortholog_one2one | 87.1383 | ENSG00000154814 | OXNAD1 | ortholog_one2one | 83.2797 | NA | NA | NA | NA | NA | NA | 218885 | 218885 | 92106 | 92106 |
| ENSMOCG00000004856 | 1774.616709 | 0.3176813 | 0.0453472 | 0.0000000 | 0.0000000 | 101983306 | Pcdh17 | protein_coding | 101983306 | Pcdh17 | ENSMUSG00000035566 | Pcdh17 | ortholog_one2one | 98.8783 | ENSG00000118946 | PCDH17 | ortholog_one2one | 98.2744 | NA | NA | NA | NA | NA | NA | 219228 | 219228 | 27253 | 27253 |
| ENSMOCG00000019047 | 600.704988 | 0.2722218 | 0.0383740 | 0.0000000 | 0.0000000 | 101984161 | Sh3bp5 | protein_coding | 101984161 | Sh3bp5 | ENSMUSG00000021892 | Sh3bp5 | ortholog_one2one | 94.3231 | ENSG00000131370 | SH3BP5 | ortholog_one2one | 91.4847 | NA | NA | NA | NA | NA | NA | 24056 | 24056 | 9467 | 9467 |
| ENSMOCG00000017020 | 542.561619 | -0.3197766 | 0.0460404 | 0.0000000 | 0.0000000 | 101993491 | Tbkbp1 | protein_coding | 101993491 | Tbkbp1 | ENSMUSG00000038517 | Tbkbp1 | ortholog_one2one | 96.5742 | ENSG00000198933 | TBKBP1 | ortholog_one2one | 93.1485 | NA | NA | NA | NA | NA | NA | 73174 | 73174 | 9755 | 9755 |
| ENSMOCG00000014883 | 208.760682 | 0.7315658 | 0.1036807 | 0.0000000 | 0.0000000 | 101998102 | Mlip | protein_coding | 101998102 | Mlip | ENSMUSG00000032355 | Mlip | ortholog_one2one | 81.1594 | ENSG00000146147 | MLIP | ortholog_one2one | 71.2215 | NA | NA | NA | NA | NA | NA | 69642 | 69642 | 90523, 101927189 | 90523 |
| ENSMOCG00000019081 | 2065.974791 | 0.2826410 | 0.0402136 | 0.0000000 | 0.0000000 | 101991872 | Cacna1e | protein_coding | 101991872 | Cacna1e | ENSMUSG00000004110 | Cacna1e | ortholog_one2one | 96.7420 | ENSG00000198216 | CACNA1E | ortholog_one2one | 95.6560 | NA | NA | NA | NA | NA | NA | 12290 | 12290 | 777 | 777 |
| ENSMOCG00000022869 | 2469.088587 | 0.3187510 | 0.0460921 | 0.0000000 | 0.0000000 | 101986595 | Snca | protein_coding | 101986595 | Snca | ENSMUSG00000025889 | Snca | ortholog_one2one | 99.2857 | ENSG00000145335 | SNCA | ortholog_one2one | 95.0000 | NA | NA | NA | NA | NA | NA | 20617 | 20617 | 6622 | 6622 |
| ENSMOCG00000007772 | 197.208242 | -0.4788712 | 0.0721468 | 0.0000000 | 0.0000000 | 101984170 | Itga3 | protein_coding | 101984170 | Itga3 | ENSMUSG00000001507 | Itga3 | ortholog_one2one | 91.2464 | ENSG00000005884 | ITGA3 | ortholog_one2one | 87.4405 | NA | NA | NA | NA | NA | NA | 16400 | 16400 | 3675 | 3675 |
| ENSMOCG00000019201 | 788.624889 | -0.5880906 | 0.0862753 | 0.0000000 | 0.0000000 | 101997198 | Vamp1 | protein_coding | 101997198 | Vamp1 | ENSMUSG00000030337 | Vamp1 | ortholog_one2one | 94.0678 | ENSG00000139190 | VAMP1 | ortholog_one2one | 97.4576 | NA | NA | NA | NA | NA | NA | 22317, 78668 | 22317 | 6843 | 6843 |
| ENSMOCG00000007372 | 140.645182 | 0.7865425 | 0.1120247 | 0.0000000 | 0.0000000 | 101998657 | Tecta | protein_coding | 101998657 | Tecta | ENSMUSG00000037705 | Tecta | ortholog_one2one | 98.4230 | ENSG00000109927 | TECTA | ortholog_one2one | 96.0111 | NA | NA | NA | NA | NA | NA | 21683 | 21683 | 7007, 116804918 | 7007 |
| ENSMOCG00000000889 | 389.743678 | -0.6107087 | 0.0891701 | 0.0000000 | 0.0000000 | 101983268 | Tac2 | protein_coding | 101983268 | Tac2 | ENSMUSG00000025400 | Tac2 | ortholog_one2one | 79.8319 | ENSG00000166863 | TAC3 | ortholog_one2one | 60.5042 | NA | NA | NA | NA | NA | NA | 21334 | 21334 | 6866 | 6866 |
| ENSMOCG00000022450 | 132.161361 | -0.8784182 | 0.1259144 | 0.0000000 | 0.0000000 | 101998127 | Vwa3a | protein_coding | 101998127 | Vwa3a | ENSMUSG00000030889 | Vwa3a | ortholog_one2one | 81.7391 | ENSG00000175267 | VWA3A | ortholog_one2one | 73.5652 | NA | NA | NA | NA | NA | NA | 233813 | 233813 | 146177 | 146177 |
| ENSMOCG00000021066 | 2497.131915 | 0.2514484 | 0.0356086 | 0.0000000 | 0.0000000 | 101986394 | Cracdl | protein_coding | 101986394 | Cracdl | ENSMUSG00000026090 | Cracdl | ortholog_one2one | 79.8148 | ENSG00000196872 | CRACDL | ortholog_one2one | 56.2963 | NA | NA | NA | NA | NA | NA | 72097 | 72097 | 343990 | 343990 |
| ENSMOCG00000022659 | 253.793516 | -0.8516675 | 0.1219530 | 0.0000000 | 0.0000000 | 101987554 | Elfn1 | protein_coding | 101987554 | Elfn1 | ENSMUSG00000048988 | Elfn1 | ortholog_one2one | 96.6265 | ENSG00000225968 | ELFN1 | ortholog_one2one | 87.7108 | NA | NA | NA | NA | NA | NA | 243312 | 243312 | 392617 | 392617 |
| ENSMOCG00000013860 | 27.868455 | -5.4817301 | 0.7618005 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000012580 | 167.671833 | -0.4550246 | 0.0693964 | 0.0000000 | 0.0000000 | 101996732 | Cand2 | protein_coding | 101996732 | Cand2 | ENSMUSG00000030319 | Cand2 | ortholog_one2one | 95.3884 | ENSG00000144712 | CAND2 | ortholog_one2one | 91.2621 | NA | NA | NA | NA | NA | NA | 67088 | 67088 | 23066 | 23066 |
| ENSMOCG00000000362 | 1251.918804 | 0.2552235 | 0.0365192 | 0.0000000 | 0.0000000 | 102002657 | Dmxl1 | protein_coding | 102002657 | Dmxl1 | ENSMUSG00000037416 | Dmxl1 | ortholog_one2one | 92.0515 | ENSG00000172869 | DMXL1 | ortholog_one2one | 90.0066 | NA | NA | NA | NA | NA | NA | 240283 | 240283 | 1657 | 1657 |
| ENSMOCG00000006434 | 1101.342171 | 0.2986016 | 0.0435139 | 0.0000000 | 0.0000000 | 101988288 | Ppp4r4 | protein_coding | 101988288 | Ppp4r4 | ENSMUSG00000021209 | Ppp4r4 | ortholog_one2one | 94.7368 | ENSG00000119698 | PPP4R4 | ortholog_one2one | 91.6476 | NA | NA | NA | NA | NA | NA | 74521 | 74521 | 57718 | 57718 |
| ENSMOCG00000001420 | 465.571908 | 0.2895009 | 0.0420296 | 0.0000000 | 0.0000000 | 101988386 | Lrtm2 | protein_coding | 101988386 | Lrtm2 | ENSMUSG00000055003 | Lrtm2 | ortholog_one2one | 96.2162 | ENSG00000166159 | LRTM2 | ortholog_one2one | 90.5405 | NA | NA | NA | NA | NA | NA | 211187 | 211187 | 654429 | 654429 |
| ENSMOCG00000005135 | 33.771866 | 0.9469569 | 0.1389536 | 0.0000000 | 0.0000000 | 101985398 | Acpp | protein_coding | 101985398 | Acpp | ENSMUSG00000032561 | Acpp | ortholog_one2one | 87.4699 | ENSG00000014257 | ACP3 | ortholog_one2one | 75.4217 | NA | NA | NA | NA | NA | NA | 56318 | 56318 | 55 | 55 |
| ENSMOCG00000004219 | 569.069146 | -0.4257036 | 0.0654453 | 0.0000000 | 0.0000000 | 101982188 | Ttyh2 | protein_coding | 101982188 | Ttyh2 | ENSMUSG00000034714 | Ttyh2 | ortholog_one2one | 93.6090 | ENSG00000141540 | TTYH2 | ortholog_one2one | 83.2707 | NA | NA | NA | NA | NA | NA | 117160 | 117160 | 94015 | 94015 |
| ENSMOCG00000018809 | 1015.258734 | 0.2639881 | 0.0381825 | 0.0000000 | 0.0000000 | 101993475 | Dennd11 | protein_coding | 101993475 | Dennd11 | ENSMUSG00000037172 | Dennd11 | ortholog_one2one | 98.9011 | ENSG00000257093 | DENND11 | ortholog_one2one | 96.7033 | NA | NA | NA | NA | NA | NA | 243780 | 243780 | 57189 | 57189 |
| ENSMOCG00000010553 | 636.658293 | -0.2926992 | 0.0429912 | 0.0000000 | 0.0000000 | 101992834 | Aifm3 | protein_coding | 101992834 | Aifm3 | ENSMUSG00000022763 | Aifm3 | ortholog_one2one | 98.5124 | ENSG00000183773 | AIFM3 | ortholog_one2one | 96.1983 | NA | NA | NA | NA | NA | NA | 72168 | 72168 | 150209 | 150209 |
| ENSMOCG00000009992 | 150.529353 | -0.5828053 | 0.0880785 | 0.0000000 | 0.0000000 | 101997095 | Ankrd6 | protein_coding | 101997095 | Ankrd6 | ENSMUSG00000040183 | Ankrd6 | ortholog_one2one | 92.5035 | ENSG00000135299 | ANKRD6 | ortholog_one2one | 85.1485 | NA | NA | NA | NA | NA | NA | 140577 | 140577 | 22881 | 22881 |
| ENSMOCG00000020252 | 122.136116 | 0.8138362 | 0.1197303 | 0.0000000 | 0.0000000 | 101985388 | Micall2 | protein_coding | 101985388 | Micall2 | ENSMUSG00000036718 | Micall2 | ortholog_one2one | 74.7379 | ENSG00000164877 | MICALL2 | ortholog_one2one | 53.7736 | NA | NA | NA | NA | NA | NA | 231830 | 231830 | 79778 | 79778 |
| ENSMOCG00000001238 | 59.252438 | -6.4644464 | 0.9296445 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000016241 | 8.184351 | 3.0330309 | 0.4788398 | 0.0000000 | 0.0000000 | 102001657 | Epgn | protein_coding | 102001657 | Epgn | ENSMUSG00000035020 | Epgn | ortholog_one2one | 84.5161 | ENSG00000182585 | EPGN | ortholog_one2one | 75.4839 | NA | NA | NA | NA | NA | NA | 71920 | 71920 | 255324 | 255324 |
| ENSMOCG00000021978 | 2503.981650 | 0.3913382 | 0.0606232 | 0.0000000 | 0.0000000 | 101996070 | Ano3 | protein_coding | 101996070 | Ano3 | ENSMUSG00000074968 | Ano3 | ortholog_one2one | 98.1651 | ENSG00000134343 | ANO3 | ortholog_one2one | 94.0877 | NA | NA | NA | NA | NA | NA | 228432 | 228432 | 63982 | 63982 |
| ENSMOCG00000020214 | 707.641397 | 0.3375169 | 0.0511318 | 0.0000000 | 0.0000000 | 101993354 | Epha7 | protein_coding | 101993354 | Epha7 | ENSMUSG00000028289 | Epha7 | ortholog_one2one | 98.9980 | ENSG00000135333 | EPHA7 | ortholog_one2one | 98.6974 | NA | NA | NA | NA | NA | NA | 13841 | 13841 | 2045 | 2045 |
| ENSMOCG00000011597 | 80.225014 | -0.6579311 | 0.0984148 | 0.0000000 | 0.0000000 | 102000152 | Alpl | protein_coding | 102000152 | Alpl | ENSMUSG00000028766 | Alpl | ortholog_one2one | 95.4198 | ENSG00000162551 | ALPL | ortholog_one2one | 91.0305 | NA | NA | NA | NA | NA | NA | 11647 | 11647 | 249 | 249 |
| ENSMOCG00000017841 | 176.283261 | -0.5212606 | 0.0812717 | 0.0000000 | 0.0000000 | 102002199 | Arhgef37 | protein_coding | 102002199 | Arhgef37 | ENSMUSG00000045094 | Arhgef37 | ortholog_one2one | 87.8698 | ENSG00000183111 | ARHGEF37 | ortholog_one2one | 80.7692 | NA | NA | NA | NA | NA | NA | 328967 | 328967 | 389337 | 389337 |
| ENSMOCG00000017301 | 232.088980 | -0.4152807 | 0.0650491 | 0.0000000 | 0.0000000 | 101990908 | Arhgef28 | protein_coding | 101990908 | Arhgef28 | ENSMUSG00000021662 | Arhgef28 | ortholog_one2one | 88.8624 | ENSG00000214944 | ARHGEF28 | ortholog_one2one | 79.7498 | NA | NA | NA | NA | NA | NA | 110596 | 110596 | 64283 | 64283 |
| ENSMOCG00000010940 | 8751.424195 | 0.2519632 | 0.0372424 | 0.0000000 | 0.0000000 | 101992409 | Phactr1 | protein_coding | 101992409 | Phactr1 | ENSMUSG00000054728 | Phactr1 | ortholog_one2one | 97.8428 | ENSG00000112137 | PHACTR1 | ortholog_one2one | 86.4407 | NA | NA | NA | NA | NA | NA | 218194 | 218194 | 221692 | 221692 |
| ENSMOCG00000006730 | 549.511990 | 0.3376728 | 0.0517863 | 0.0000000 | 0.0000000 | 101995770 | Tmod1 | protein_coding | 101995770 | Tmod1 | ENSMUSG00000028328 | Tmod1 | ortholog_one2one | 98.6072 | ENSG00000136842 | TMOD1 | ortholog_one2one | 96.1003 | NA | NA | NA | NA | NA | NA | 21916 | 21916 | 7111 | 7111 |
| ENSMOCG00000015544 | 210.939251 | 0.7210888 | 0.1081617 | 0.0000000 | 0.0000000 | 101993756 | Pdzrn3 | protein_coding | 101993756 | Pdzrn3 | ENSMUSG00000035357 | Pdzrn3 | ortholog_one2one | 98.3067 | ENSG00000121440 | PDZRN3 | ortholog_one2one | 95.2023 | NA | NA | NA | NA | NA | NA | 55983 | 55983 | 23024 | 23024 |
| ENSMOCG00000011021 | 3083.937656 | 0.2777951 | 0.0415103 | 0.0000000 | 0.0000000 | 101994616 | Gucy1b1 | protein_coding | 101994616 | Gucy1b1 | ENSMUSG00000028005 | Gucy1b1 | ortholog_one2one | 97.5845 | ENSG00000061918 | GUCY1B1 | ortholog_one2one | 98.2287 | NA | NA | NA | NA | NA | NA | 54195 | 54195 | 2983 | 2983 |
| ENSMOCG00000021415 | 137.545095 | -0.6423016 | 0.0985472 | 0.0000000 | 0.0000000 | 101979864 | Cyp4x1 | protein_coding | 101979864 | Cyp4x1 | ENSMUSG00000047155 | Cyp4x1 | ortholog_one2one | 90.9091 | ENSG00000186377 | CYP4X1 | ortholog_one2one | 71.9368 | NA | NA | NA | NA | NA | NA | 81906 | 81906 | 260293 | 260293 |
| ENSMOCG00000019986 | 32.013461 | -1.1206787 | 0.1778611 | 0.0000000 | 0.0000000 | 101993862 | Sh3tc1 | protein_coding | 101993862 | Sh3tc1 | ENSMUSG00000036553 | Sh3tc1 | ortholog_one2one | 89.9479 | ENSG00000125089 | SH3TC1 | ortholog_one2one | 72.4497 | NA | NA | NA | NA | NA | NA | 231147 | 231147 | 54436 | 54436 |
| ENSMOCG00000018490 | 2069.119113 | 0.2582331 | 0.0386987 | 0.0000000 | 0.0000000 | 101981065 | Smad3 | protein_coding | 101981065 | Smad3 | ENSMUSG00000032402 | Smad3 | ortholog_one2one | 100.0000 | ENSG00000166949 | SMAD3 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 17127 | 17127 | 4088 | 4088 |
| ENSMOCG00000001493 | 129.286134 | -0.6118159 | 0.0949191 | 0.0000000 | 0.0000000 | 101992631 | Psph | protein_coding | 101992631 | Psph | ENSMUSG00000029446 | Psph | ortholog_one2one | 96.4444 | ENSG00000146733 | PSPH | ortholog_one2one | 92.0000 | NA | NA | NA | NA | NA | NA | 100678 | 100678 | 5723 | 5723 |
| ENSMOCG00000017138 | 731.352977 | 0.2699359 | 0.0406952 | 0.0000000 | 0.0000000 | 101998507 | Kcnq3 | protein_coding | 101998507 | Kcnq3 | ENSMUSG00000056258 | Kcnq3 | ortholog_one2one | 98.3963 | ENSG00000184156 | KCNQ3 | ortholog_one2one | 95.5326 | NA | NA | NA | NA | NA | NA | 110862 | 110862 | 3786 | 3786 |
| ENSMOCG00000021840 | 976.895583 | 0.3384763 | 0.0527652 | 0.0000000 | 0.0000000 | 101997361 | Camk4 | protein_coding | 101997361 | Camk4 | ENSMUSG00000038128 | Camk4 | ortholog_one2one | 82.8704 | ENSG00000152495 | CAMK4 | ortholog_one2one | 81.0185 | NA | NA | NA | NA | NA | NA | 12326 | 12326 | 814 | 814 |
| ENSMOCG00000012241 | 35.590524 | -1.0659671 | 0.1682393 | 0.0000000 | 0.0000000 | 101988527 | Fads6 | protein_coding | 101988527 | Fads6 | ENSMUSG00000044788 | Fads6 | ortholog_one2one | 88.8889 | ENSG00000172782 | FADS6 | ortholog_one2one | 79.8246 | NA | NA | NA | NA | NA | NA | 328035 | 328035 | 283985 | 283985 |
| ENSMOCG00000019874 | 181.764715 | -0.5170787 | 0.0831383 | 0.0000000 | 0.0000000 | 101990699 | Cdr2l | protein_coding | 101990699 | Cdr2l | ENSMUSG00000050910 | Cdr2l | ortholog_one2one | 97.4194 | ENSG00000109089 | CDR2L | ortholog_one2one | 93.7634 | NA | NA | NA | NA | NA | NA | 237988 | 237988 | 30850 | 30850 |
| ENSMOCG00000022468 | 1445.284314 | 0.2949394 | 0.0451895 | 0.0000000 | 0.0000000 | 101994537 | Cacnb4 | protein_coding | 101994537 | Cacnb4 | ENSMUSG00000017412 | Cacnb4 | ortholog_one2one | 99.0366 | ENSG00000182389 | CACNB4 | ortholog_one2one | 98.4586 | NA | NA | NA | NA | NA | NA | 12298 | 12298 | 785 | 785 |
| ENSMOCG00000014104 | 1146.082514 | 0.2861557 | 0.0437484 | 0.0000000 | 0.0000000 | 101987971 | Gpr158 | protein_coding | 101987971 | Gpr158 | ENSMUSG00000045967 | Gpr158 | ortholog_one2one | 91.5423 | ENSG00000151025 | GPR158 | ortholog_one2one | 86.8159 | NA | NA | NA | NA | NA | NA | 241263 | 241263 | 57512 | 57512 |
| ENSMOCG00000019489 | 5124.809781 | 0.2590073 | 0.0392735 | 0.0000000 | 0.0000000 | 101999295 | Ppp2r2c | protein_coding | 101999295 | Ppp2r2c | ENSMUSG00000029120 | Ppp2r2c | ortholog_one2one | 99.5526 | ENSG00000074211 | PPP2R2C | ortholog_one2one | 99.5526 | NA | NA | NA | NA | NA | NA | 269643 | 269643 | 5522 | 5522 |
| ENSMOCG00000009885 | 1187.767358 | 0.2575088 | 0.0390848 | 0.0000000 | 0.0000000 | 101990061 | Strn | protein_coding | 101990061 | Strn | ENSMUSG00000024077 | Strn | ortholog_one2one | 96.7949 | ENSG00000115808 | STRN | ortholog_one2one | 96.9231 | NA | NA | NA | NA | NA | NA | 268980 | 268980 | 6801 | 6801 |
| ENSMOCG00000016754 | 312.178865 | -0.3723388 | 0.0597956 | 0.0000000 | 0.0000000 | 101980044 | Plxnb3 | protein_coding | 101980044 | Plxnb3 | ENSMUSG00000031385 | Plxnb3 | ortholog_one2one | 91.4916 | ENSG00000198753 | PLXNB3 | ortholog_one2one | 85.0840 | NA | NA | NA | NA | NA | NA | 140571 | 140571 | 5365 | 5365 |
| ENSMOCG00000021091 | 58.749681 | -0.8276528 | 0.1275414 | 0.0000000 | 0.0000000 | 101987165 | Lamc2 | protein_coding | 101987165 | Lamc2 | ENSMUSG00000026479 | Lamc2 | ortholog_one2one | 90.2685 | ENSG00000058085 | LAMC2 | ortholog_one2one | 82.4664 | NA | NA | NA | NA | NA | NA | 16782 | 16782 | 3918 | 3918 |
| ENSMOCG00000001939 | 493.434467 | -0.5700352 | 0.0914058 | 0.0000000 | 0.0000000 | 101987384 | Ece2 | protein_coding | 101987384 | Ece2 | ENSMUSG00000022842 | Ece2 | ortholog_one2one | 79.6053 | ENSG00000145194 | ECE2 | ortholog_one2one | 76.2061 | NA | NA | NA | NA | NA | NA | 107522 | 107522 | 9718 | 9718 |
| ENSMOCG00000022678 | 114.598044 | -0.5849759 | 0.0933793 | 0.0000000 | 0.0000000 | 102001737 | Epha10 | protein_coding | 102001737 | Epha10 | ENSMUSG00000028876 | Epha10 | ortholog_one2one | 82.3944 | ENSG00000183317 | EPHA10 | ortholog_one2one | 92.6559 | NA | NA | NA | NA | NA | NA | 230735 | 230735 | 284656 | 284656 |
| ENSMOCG00000006680 | 602.874786 | -0.5280717 | 0.0861088 | 0.0000000 | 0.0000000 | 101978857 | Sez6l | protein_coding | 101978857 | Sez6l | ENSMUSG00000058153 | Sez6l | ortholog_one2one | 93.9834 | ENSG00000100095 | SEZ6L | ortholog_one2one | 85.0622 | NA | NA | NA | NA | NA | NA | 56747 | 56747 | 23544 | 23544 |
| ENSMOCG00000016633 | 1353.437399 | 0.2855533 | 0.0442622 | 0.0000000 | 0.0000000 | 102000265 | Osbpl8 | protein_coding | 102000265 | Osbpl8 | ENSMUSG00000020189 | Osbpl8 | ortholog_one2one | 95.4338 | ENSG00000091039 | OSBPL8 | ortholog_one2one | 95.7763 | NA | NA | NA | NA | NA | NA | 237542 | 237542 | 114882 | 114882 |
| ENSMOCG00000006588 | 265.076319 | -0.2976405 | 0.0464370 | 0.0000000 | 0.0000000 | 106144272 | Mrps6 | protein_coding | 106144272 | Mrps6 | ENSMUSG00000039680 | Mrps6 | ortholog_one2one | 93.6000 | ENSG00000243927 | MRPS6 | ortholog_one2one | 81.6000 | NA | NA | NA | NA | NA | NA | 121022 | 121022 | 64968 | 64968 |
| ENSMOCG00000019723 | 677.930072 | 0.6228930 | 0.0989372 | 0.0000000 | 0.0000000 | NA | Coch | protein_coding | NA | Coch | ENSMUSG00000020953 | Coch | ortholog_one2one | 96.9231 | ENSG00000100473 | COCH | ortholog_one2one | 95.5769 | NA | NA | NA | NA | NA | NA | 12810 | 12810 | 1690 | 1690 |
| ENSMOCG00000005438 | 2422.556696 | 0.2734516 | 0.0422775 | 0.0000000 | 0.0000000 | 102002034 | Epha4 | protein_coding | 102002034 | Epha4 | ENSMUSG00000026235 | Epha4 | ortholog_one2one | 99.2901 | ENSG00000116106 | EPHA4 | ortholog_one2one | 98.4787 | NA | NA | NA | NA | NA | NA | 13838 | 13838 | 2043 | 2043 |
| ENSMOCG00000006938 | 427.374325 | 0.3594227 | 0.0584078 | 0.0000000 | 0.0000000 | 101980108 | Zfp385b | protein_coding | 101980108 | Zfp385b | ENSMUSG00000027016 | Zfp385b | ortholog_one2one | 95.1087 | ENSG00000144331 | ZNF385B | ortholog_one2one | 93.4783 | NA | NA | NA | NA | NA | NA | 241494 | 241494 | 151126 | 151126 |
| ENSMOCG00000005835 | 1831.002647 | 0.2926100 | 0.0460217 | 0.0000000 | 0.0000000 | 101983212 | Rarb | protein_coding | 101983212 | Rarb | ENSMUSG00000017491 | Rarb | ortholog_one2one | 99.3304 | ENSG00000077092 | RARB | ortholog_one2one | 98.2143 | NA | NA | NA | NA | NA | NA | 218772 | 218772 | 5915 | 5915 |
| ENSMOCG00000009188 | 69.405197 | -0.6213034 | 0.0999430 | 0.0000000 | 0.0000000 | 101993721 | Dock5 | protein_coding | 101993721 | Dock5 | ENSMUSG00000044447 | Dock5 | ortholog_one2one | 97.1092 | ENSG00000147459 | DOCK5 | ortholog_one2one | 94.4861 | NA | NA | NA | NA | NA | NA | 68813 | 68813 | 80005 | 80005 |
| ENSMOCG00000018761 | 105.888966 | -0.4544448 | 0.0762793 | 0.0000000 | 0.0000000 | 101985227 | Pdlim4 | protein_coding | 101985227 | Pdlim4 | ENSMUSG00000020388 | Pdlim4 | ortholog_one2one | 95.1515 | ENSG00000131435 | PDLIM4 | ortholog_one2one | 89.3939 | NA | NA | NA | NA | NA | NA | 30794 | 30794 | 8572 | 8572 |
| ENSMOCG00000009245 | 155.699813 | -0.6938695 | 0.1101379 | 0.0000000 | 0.0000000 | NA | Obscn | protein_coding | NA | Obscn | ENSMUSG00000061462 | Obscn | ortholog_one2one | 82.6959 | ENSG00000154358 | OBSCN | ortholog_one2one | 71.0121 | NA | NA | NA | NA | NA | NA | 380698 | 380698 | 84033 | 84033 |
| ENSMOCG00000004120 | 1776.033918 | 0.2602212 | 0.0407092 | 0.0000000 | 0.0000000 | 101998432 | Gabra4 | protein_coding | 101998432 | Gabra4 | ENSMUSG00000029211 | Gabra4 | ortholog_one2one | 95.4628 | ENSG00000109158 | GABRA4 | ortholog_one2one | 89.6552 | NA | NA | NA | NA | NA | NA | 14397 | 14397 | 2557 | 2557 |
| ENSMOCG00000008629 | 68.839856 | -0.6074318 | 0.0988206 | 0.0000000 | 0.0000000 | 101981613 | Tmem88b | protein_coding | 101981613 | Tmem88b | ENSMUSG00000073680 | Tmem88b | ortholog_one2one | 79.3296 | ENSG00000205116 | TMEM88B | ortholog_one2one | 65.9218 | NA | NA | NA | NA | NA | NA | 320587 | 320587 | 643965 | 643965 |
| ENSMOCG00000011248 | 891.379523 | -0.2624029 | 0.0411292 | 0.0000000 | 0.0000000 | 101995166 | Rabggtb | protein_coding | 101995166 | Rabggtb | ENSMUSG00000038975 | Rabggtb | ortholog_one2one | 98.4663 | ENSG00000137955 | RABGGTB | ortholog_one2one | 97.2393 | NA | NA | NA | NA | NA | NA | 19352 | 19352 | 5876 | 5876 |
| ENSMOCG00000011224 | 2187.311983 | 0.2890264 | 0.0459281 | 0.0000000 | 0.0000000 | 101988616 | Mmd | protein_coding | 101988616 | Mmd | ENSMUSG00000003948 | Mmd | ortholog_one2one | 98.3193 | ENSG00000108960 | MMD | ortholog_one2one | 97.4790 | NA | NA | NA | NA | NA | NA | 67468 | 67468 | 23531 | 23531 |
| ENSMOCG00000006768 | 19653.851448 | 0.2781339 | 0.0440321 | 0.0000000 | 0.0000000 | 101998884 | Camk2a | protein_coding | 101998884 | Camk2a | ENSMUSG00000024617 | Camk2a | ortholog_one2one | 100.0000 | ENSG00000070808 | CAMK2A | ortholog_one2one | 99.7955 | NA | NA | NA | NA | NA | NA | 12322 | 12322 | 815 | 815 |
| ENSMOCG00000013444 | 463.398189 | 0.2624365 | 0.0414366 | 0.0000000 | 0.0000000 | 101986228 | Dlgap2 | protein_coding | 101986228 | Dlgap2 | ENSMUSG00000047495 | Dlgap2 | ortholog_one2one | 96.6038 | ENSG00000198010 | DLGAP2 | ortholog_one2one | 90.4717 | NA | NA | NA | NA | NA | NA | 244310 | 244310 | 9228 | 9228 |
| ENSMOCG00000007173 | 329.200500 | 0.2772222 | 0.0442269 | 0.0000000 | 0.0000000 | 101998243 | Reps2 | protein_coding | 101998243 | Reps2 | ENSMUSG00000040855 | Reps2 | ortholog_one2one | 93.5285 | ENSG00000169891 | REPS2 | ortholog_one2one | 88.5978 | NA | NA | NA | NA | NA | NA | 194590 | 194590 | 9185 | 9185 |
| ENSMOCG00000008079 | 231.677280 | -0.6886401 | 0.1115055 | 0.0000000 | 0.0000000 | 101980707 | Adgra1 | protein_coding | 101980707 | Adgra1 | ENSMUSG00000025475 | Adgra1 | ortholog_one2one | 96.7185 | ENSG00000197177 | ADGRA1 | ortholog_one2one | 80.8290 | NA | NA | NA | NA | NA | NA | 52389 | 52389 | 84435 | 84435 |
| ENSMOCG00000000458 | 12391.472589 | 0.3020567 | 0.0489737 | 0.0000000 | 0.0000000 | 101984464 | Hpca | protein_coding | 101984464 | Hpca | ENSMUSG00000028785 | Hpca | ortholog_one2one | 100.0000 | ENSG00000121905 | HPCA | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 15444 | 15444 | 3208 | 3208 |
| ENSMOCG00000016073 | 1737.051691 | 0.2713706 | 0.0436688 | 0.0000000 | 0.0000000 | 101980898 | Brinp1 | protein_coding | 101980898 | Brinp1 | ENSMUSG00000028351 | Brinp1 | ortholog_one2one | 99.4737 | ENSG00000078725 | BRINP1 | ortholog_one2one | 98.8158 | NA | NA | NA | NA | NA | NA | 56710 | 56710 | 1620 | 1620 |
| ENSMOCG00000009746 | 261.317224 | -0.3380505 | 0.0563111 | 0.0000000 | 0.0000000 | NA | Arhgef1 | protein_coding | NA | Arhgef1 | ENSMUSG00000040940 | Arhgef1 | ortholog_one2one | 91.8033 | ENSG00000076928 | ARHGEF1 | ortholog_one2one | 88.0874 | NA | NA | NA | NA | NA | NA | 16801 | 16801 | 9138 | 9138 |
| ENSMOCG00000009230 | 71.273484 | -0.6592225 | 0.1086934 | 0.0000000 | 0.0000000 | 101986480 | Gjb1 | protein_coding | 101986480 | Gjb1 | ENSMUSG00000047797 | Gjb1 | ortholog_one2one | 97.5265 | ENSG00000169562 | GJB1 | ortholog_one2one | 97.5265 | NA | NA | NA | NA | NA | NA | 14618 | 14618 | 2705 | 2705 |
| ENSMOCG00000010349 | 17.801133 | -5.0340975 | 0.7893817 | 0.0000000 | 0.0000000 | 101979077 | protein_coding | 101979077 | ENSMUSG00000060743 | H3f3a | ortholog_one2one | 96.3235 | ENSG00000132475 | H3-3B | ortholog_one2many | 96.3235 | ENSMUSG00000060743, ENSMUSG00000060743 | H3f3a, H3f3a | 96.3235, 96.3235 | ENSG00000132475, ENSG00000188375 | H3-3B, H3-5 | 96.3235, 89.7059 | 15078 | 15078 | 3021 | 3021 | ||
| ENSMOCG00000017839 | 211.622729 | -0.6444556 | 0.1074146 | 0.0000000 | 0.0000000 | 101982560 | Ace | protein_coding | 101982560 | Ace | ENSMUSG00000020681 | Ace | ortholog_one2one | 88.9482 | ENSG00000159640 | ACE | ortholog_one2one | 83.0793 | NA | NA | NA | NA | NA | NA | 11421 | 11421 | 1636 | 1636 |
| ENSMOCG00000016899 | 1207.345043 | 0.2959254 | 0.0486925 | 0.0000000 | 0.0000000 | 101995277 | Cobl | protein_coding | 101995277 | Cobl | ENSMUSG00000020173 | Cobl | ortholog_one2one | 82.2521 | ENSG00000106078 | COBL | ortholog_one2one | 63.6838 | NA | NA | NA | NA | NA | NA | 12808 | 12808 | 23242 | 23242 |
| ENSMOCG00000001119 | 59.147890 | -0.6304867 | 0.1059307 | 0.0000000 | 0.0000000 | NA | Igsf10 | protein_coding | NA | Igsf10 | ENSMUSG00000036334 | Igsf10 | ortholog_one2one | 74.4788 | ENSG00000152580 | IGSF10 | ortholog_one2one | 65.5598 | NA | NA | NA | NA | NA | NA | 242050 | 242050 | 285313 | 285313 |
| ENSMOCG00000011126 | 3066.773663 | 0.3694112 | 0.0633408 | 0.0000000 | 0.0000000 | 101994931 | Scn4b | protein_coding | 101994931 | Scn4b | ENSMUSG00000046480 | Scn4b | ortholog_one2one | 91.2281 | ENSG00000177098 | SCN4B | ortholog_one2one | 83.3333 | NA | NA | NA | NA | NA | NA | 399548 | 399548 | 6330 | 6330 |
| ENSMOCG00000002012 | 132.327081 | -0.3875227 | 0.0670010 | 0.0000000 | 0.0000000 | 101986831 | Efs | protein_coding | 101986831 | Efs | ENSMUSG00000022203 | Efs | ortholog_one2one | 89.9267 | ENSG00000100842 | EFS | ortholog_one2one | 82.6007 | NA | NA | NA | NA | NA | NA | 13644 | 13644 | 10278 | 10278 |
| ENSMOCG00000012564 | 182.075773 | 0.6009579 | 0.1023754 | 0.0000000 | 0.0000000 | 101996484 | Stra6 | protein_coding | 101996484 | Stra6 | ENSMUSG00000032327 | Stra6 | ortholog_one2one | 86.4179 | ENSG00000137868 | STRA6 | ortholog_one2one | 74.7761 | NA | NA | NA | NA | NA | NA | 20897 | 20897 | 64220 | 64220 |
| ENSMOCG00000012867 | 5408.709088 | 0.2585678 | 0.0422068 | 0.0000000 | 0.0000000 | 101998640 | Ppp3r1 | protein_coding | 101998640 | Ppp3r1 | ENSMUSG00000033953 | Ppp3r1 | ortholog_one2one | 100.0000 | ENSG00000221823 | PPP3R1 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 19058 | 19058 | 5534 | 5534 |
| ENSMOCG00000016264 | 33.095341 | -0.9356930 | 0.1573726 | 0.0000000 | 0.0000000 | 101990774 | Stac | protein_coding | 101990774 | Stac | ENSMUSG00000032502 | Stac | ortholog_one2one | 93.6118 | ENSG00000144681 | STAC | ortholog_one2one | 82.8010 | NA | NA | NA | NA | NA | NA | 20840 | 20840 | 6769 | 6769 |
| ENSMOCG00000005300 | 745.047485 | 0.3232968 | 0.0547005 | 0.0000000 | 0.0000000 | 101981917 | Pfkfb3 | protein_coding | 101981917 | Pfkfb3 | ENSMUSG00000026773 | Pfkfb3 | ortholog_one2one | 98.0180 | ENSG00000170525 | PFKFB3 | ortholog_one2one | 89.0090 | NA | NA | NA | NA | NA | NA | 170768 | 170768 | 5209 | 5209 |
| ENSMOCG00000007453 | 298.778808 | 0.3712162 | 0.0646038 | 0.0000000 | 0.0000000 | 101994527 | Cntn3 | protein_coding | 101994527 | Cntn3 | ENSMUSG00000030075 | Cntn3 | ortholog_one2one | 96.0117 | ENSG00000113805 | CNTN3 | ortholog_one2one | 91.9261 | NA | NA | NA | NA | NA | NA | 18488 | 18488 | 5067 | 5067 |
| ENSMOCG00000021879 | 49.097929 | -0.5888345 | 0.1018744 | 0.0000000 | 0.0000000 | 101999714 | Ddit4l | protein_coding | 101999714 | Ddit4l | ENSMUSG00000046818 | Ddit4l | ortholog_one2one | 96.8912 | ENSG00000145358 | DDIT4L | ortholog_one2one | 94.8186 | NA | NA | NA | NA | NA | NA | 73284 | 73284 | 115265 | 115265 |
| ENSMOCG00000013868 | 55.267358 | -0.7436242 | 0.1241140 | 0.0000000 | 0.0000000 | 101998355 | Tnfrsf1a | protein_coding | 101998355 | Tnfrsf1a | ENSMUSG00000030341 | Tnfrsf1a | ortholog_one2one | 70.7965 | ENSG00000067182 | TNFRSF1A | ortholog_one2one | 60.1770 | NA | NA | NA | NA | NA | NA | 21937 | 21937 | 7132 | 7132 |
| ENSMOCG00000013163 | 1413.883475 | 0.2540315 | 0.0417662 | 0.0000000 | 0.0000000 | 101984531, 102002811 | , | protein_coding | 101984531 | ENSMUSG00000006057 | Atp5g1 | ortholog_one2many | 94.9640 | NA | NA | NA | NA | NA | NA | NA | 11951 | 11951 | NA | NA | ||||
| ENSMOCG00000017595 | 538.109436 | 0.2894597 | 0.0484585 | 0.0000000 | 0.0000000 | 101989545 | Slc7a8 | protein_coding | 101989545 | Slc7a8 | ENSMUSG00000022180 | Slc7a8 | ortholog_one2one | 94.7664 | ENSG00000092068 | SLC7A8 | ortholog_one2one | 92.5234 | NA | NA | NA | NA | NA | NA | 50934 | 50934 | 23428 | 23428 |
| ENSMOCG00000011500 | 1570.056024 | 0.2620988 | 0.0434128 | 0.0000000 | 0.0000000 | 101980003 | Ets2 | protein_coding | 101980003 | Ets2 | ENSMUSG00000022895 | Ets2 | ortholog_one2one | 93.4043 | ENSG00000157557 | ETS2 | ortholog_one2one | 92.1277 | NA | NA | NA | NA | NA | NA | 23872 | 23872 | 2114 | 2114 |
| ENSMOCG00000016967 | 192.208601 | 0.3545281 | 0.0617309 | 0.0000000 | 0.0000000 | NA | Tbc1d4 | protein_coding | NA | Tbc1d4 | ENSMUSG00000033083 | Tbc1d4 | ortholog_one2one | 93.1212 | ENSG00000136111 | TBC1D4 | ortholog_one2one | 88.0481 | NA | NA | NA | NA | NA | NA | 210789 | 210789 | 9882 | 9882 |
| ENSMOCG00000011364 | 1503.982192 | 0.2753854 | 0.0460775 | 0.0000000 | 0.0000000 | 101979529 | Fat3 | protein_coding | 101979529 | Fat3 | ENSMUSG00000074505 | Fat3 | ortholog_one2one | 95.8865 | ENSG00000165323 | FAT3 | ortholog_one2one | 92.8729 | NA | NA | NA | NA | NA | NA | 270120 | 270120 | 120114 | 120114 |
| ENSMOCG00000014648 | 17.864312 | -1.5056239 | 0.2872870 | 0.0000000 | 0.0000000 | 101985031 | protein_coding | 101985031 | ENSMUSG00000074264 | Amy1 | ortholog_one2many | 86.1057 | NA | NA | NA | NA | NA | NA | NA | 11722 | 11722 | NA | NA | |||||
| ENSMOCG00000016548 | 261.972997 | -0.9050391 | 0.1547220 | 0.0000000 | 0.0000000 | 101995262 | Cd83 | protein_coding | 101995262 | Cd83 | ENSMUSG00000015396 | Cd83 | ortholog_one2one | 86.7347 | ENSG00000112149 | CD83 | ortholog_one2one | 68.8775 | NA | NA | NA | NA | NA | NA | 12522 | 12522 | 9308 | 9308 |
| ENSMOCG00000015575 | 2734.365857 | 0.2854782 | 0.0483842 | 0.0000000 | 0.0000000 | NA | Lmo7 | protein_coding | NA | Lmo7 | ENSMUSG00000033060 | Lmo7 | ortholog_one2one | 83.0508 | ENSG00000136153 | LMO7 | ortholog_one2one | 74.0503 | NA | NA | NA | NA | NA | NA | 380928 | 380928 | 4008 | 4008 |
| ENSMOCG00000008599 | 96.695055 | -0.5911504 | 0.1046852 | 0.0000000 | 0.0000000 | 101996718, 101997005 | , | protein_coding | 101996718 | ENSMUSG00000044816 | D630023F18Rik | ortholog_one2one | 46.7290 | ENSG00000188674 | C2orf80 | ortholog_one2one | 32.2430 | NA | NA | NA | NA | NA | NA | 98303 | 98303 | 389073 | 389073 | |
| ENSMOCG00000011415 | 33.284381 | 0.9837743 | 0.1716039 | 0.0000000 | 0.0000000 | 101988352 | Itgax | protein_coding | 101988352 | Itgax | ENSMUSG00000030789 | Itgax | ortholog_one2one | 79.8801 | ENSG00000140678 | ITGAX | ortholog_one2one | 71.4897 | NA | NA | NA | NA | NA | NA | 16411 | 16411 | 3687 | 3687 |
| ENSMOCG00000012699 | 1047.302645 | -0.5881050 | 0.1044499 | 0.0000000 | 0.0000000 | 101992060 | Podxl2 | protein_coding | 101992060 | Podxl2 | ENSMUSG00000033152 | Podxl2 | ortholog_one2one | 90.2730 | ENSG00000114631 | PODXL2 | ortholog_one2one | 76.4505 | NA | NA | NA | NA | NA | NA | 319655 | 319655 | 50512 | 50512 |
| ENSMOCG00000022040 | 130.741589 | -0.5824898 | 0.1037074 | 0.0000000 | 0.0000000 | 101983060 | Galnt6 | protein_coding | 101983060 | Galnt6 | ENSMUSG00000037280 | Galnt6 | ortholog_one2one | 92.6164 | ENSG00000139629 | GALNT6 | ortholog_one2one | 88.4430 | NA | NA | NA | NA | NA | NA | 207839 | 207839 | 11226 | 11226 |
| ENSMOCG00000021517 | 54.335103 | -0.6966189 | 0.1202844 | 0.0000000 | 0.0000000 | 101986115 | Enpp6 | protein_coding | 101986115 | Enpp6 | ENSMUSG00000038173 | Enpp6 | ortholog_one2one | 91.5909 | ENSG00000164303 | ENPP6 | ortholog_one2one | 88.8636 | NA | NA | NA | NA | NA | NA | 320981 | 320981 | 133121 | 133121 |
| ENSMOCG00000022680 | 2166.359702 | 0.3493385 | 0.0620487 | 0.0000000 | 0.0000000 | 102000203 | Pdyn | protein_coding | 102000203 | Pdyn | ENSMUSG00000027400 | Pdyn | ortholog_one2one | 79.6000 | ENSG00000101327 | PDYN | ortholog_one2one | 65.2000 | NA | NA | NA | NA | NA | NA | 18610 | 18610 | 5173 | 5173 |
| ENSMOCG00000012422 | 330.299165 | -0.6780413 | 0.1184199 | 0.0000000 | 0.0000000 | 101988412 | Camk2n2 | protein_coding | 101988412 | Camk2n2 | ENSMUSG00000051146 | Camk2n2 | ortholog_one2one | 100.0000 | ENSG00000163888 | CAMK2N2 | ortholog_one2one | 98.7342 | NA | NA | NA | NA | NA | NA | 73047 | 73047 | 94032 | 94032 |
| ENSMOCG00000006596 | 2253.956961 | 0.2592783 | 0.0441113 | 0.0000000 | 0.0000000 | 101998452 | Kcnab1 | protein_coding | 101998452 | Kcnab1 | ENSMUSG00000027827 | Kcnab1 | ortholog_one2one | 84.0399 | ENSG00000169282 | KCNAB1 | ortholog_one2one | 83.7905 | NA | NA | NA | NA | NA | NA | 16497 | 16497 | 7881 | 7881 |
| ENSMOCG00000017767 | 33.532471 | -0.9229370 | 0.1618168 | 0.0000000 | 0.0000000 | 101982983 | Nr2f2 | protein_coding | 101982983 | Nr2f2 | ENSMUSG00000030551 | Nr2f2 | ortholog_one2one | 100.0000 | ENSG00000185551 | NR2F2 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 11819 | 11819 | 7026 | 7026 |
| ENSMOCG00000016145 | 116.403793 | -0.3855859 | 0.0704209 | 0.0000000 | 0.0000000 | 101989311 | Cd82 | protein_coding | 101989311 | Cd82 | ENSMUSG00000027215 | Cd82 | ortholog_one2one | 79.8507 | ENSG00000085117 | CD82 | ortholog_one2one | 76.8657 | NA | NA | NA | NA | NA | NA | 12521 | 12521 | 3732 | 3732 |
| ENSMOCG00000006187 | 246.000714 | -0.7027129 | 0.1229596 | 0.0000000 | 0.0000000 | 101996683 | Cacna1g | protein_coding | 101996683 | Cacna1g | ENSMUSG00000020866 | Cacna1g | ortholog_one2one | 97.8992 | ENSG00000006283 | CACNA1G | ortholog_one2one | 94.7899 | NA | NA | NA | NA | NA | NA | 12291 | 12291 | 8913 | 8913 |
| ENSMOCG00000020434 | 289.838559 | -0.5549259 | 0.1014228 | 0.0000000 | 0.0000000 | 101991670 | Ramp1 | protein_coding | 101991670 | Ramp1 | ENSMUSG00000034353 | Ramp1 | ortholog_one2one | 80.4054 | ENSG00000132329 | RAMP1 | ortholog_one2one | 62.8378 | NA | NA | NA | NA | NA | NA | 51801 | 51801 | 10267 | 10267 |
| ENSMOCG00000000360 | 7.340280 | -5.5896997 | 0.9281698 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000012140 | 468.143739 | 0.2583532 | 0.0442338 | 0.0000000 | 0.0000000 | 101999297 | Hecw2 | protein_coding | 101999297 | Hecw2 | ENSMUSG00000042807 | Hecw2 | ortholog_one2one | 95.8333 | ENSG00000138411 | HECW2 | ortholog_one2one | 94.1288 | NA | NA | NA | NA | NA | NA | 329152 | 329152 | 57520 | 57520 |
| ENSMOCG00000000574 | 1188.516796 | 0.2793613 | 0.0485618 | 0.0000000 | 0.0000000 | 101984417 | Actn2 | protein_coding | 101984417 | Actn2 | ENSMUSG00000052374 | Actn2 | ortholog_one2one | 99.6644 | ENSG00000077522 | ACTN2 | ortholog_one2one | 99.1051 | NA | NA | NA | NA | NA | NA | 11472 | 11472 | 88 | 88 |
| ENSMOCG00000019160 | 198.274561 | -0.3861424 | 0.0713739 | 0.0000000 | 0.0000000 | 101982388 | Lrrc24 | protein_coding | 101982388 | Lrrc24 | ENSMUSG00000033707 | Lrrc24 | ortholog_one2one | 94.4231 | ENSG00000254402 | LRRC24 | ortholog_one2one | 83.0769 | NA | NA | NA | NA | NA | NA | 378937 | 378937 | 441381 | 441381 |
| ENSMOCG00000009867 | 492.598346 | -0.7445033 | 0.1313471 | 0.0000000 | 0.0000000 | 101979639 | Mrap2 | protein_coding | 101979639 | Mrap2 | ENSMUSG00000042761 | Mrap2 | ortholog_one2one | 90.3846 | ENSG00000135324 | MRAP2 | ortholog_one2one | 87.0192 | NA | NA | NA | NA | NA | NA | 244958 | 244958 | 112609 | 112609 |
| ENSMOCG00000014606 | 162.707309 | -0.6118670 | 0.1112545 | 0.0000000 | 0.0000000 | 101996066 | Tox2 | protein_coding | 101996066 | Tox2 | ENSMUSG00000074607 | Tox2 | ortholog_one2one | 93.1034 | ENSG00000124191 | TOX2 | ortholog_one2one | 83.9080 | NA | NA | NA | NA | NA | NA | 269389 | 269389 | 84969 | 84969 |
| ENSMOCG00000012292 | 693.347684 | -0.5030104 | 0.0945004 | 0.0000000 | 0.0000000 | 101984825 | Slc6a9 | protein_coding | 101984825 | Slc6a9 | ENSMUSG00000028542 | Slc6a9 | ortholog_one2one | 95.9248 | ENSG00000196517 | SLC6A9 | ortholog_one2one | 94.5141 | NA | NA | NA | NA | NA | NA | 14664 | 14664 | 6536 | 6536 |
| ENSMOCG00000022673 | 198.374348 | -0.2738668 | 0.0476653 | 0.0000000 | 0.0000000 | 102000749 | Gtf2ird2 | protein_coding | 102000749 | Gtf2ird2 | ENSMUSG00000015942 | Gtf2ird2 | ortholog_one2one | 86.5736 | ENSG00000174428 | GTF2IRD2B | ortholog_one2many | 79.1622 | ENSMUSG00000015942, ENSMUSG00000015942 | Gtf2ird2, Gtf2ird2 | 86.5736, 86.5736 | ENSG00000174428, ENSG00000196275 | GTF2IRD2B, GTF2IRD2 | 79.1622, 78.9474 | 114674 | 114674 | 389524 | 389524 |
| ENSMOCG00000010337 | 41.204043 | -5.8087576 | 0.9750413 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | NA | ENSG00000111640 | GAPDH | ortholog_one2many | 74.7253 | NA | NA | NA | NA | NA | NA | NA | NA | 2597 | 2597 | |||||
| ENSMOCG00000020972 | 14.428405 | -1.2441711 | 0.2405523 | 0.0000000 | 0.0000000 | 101985696 | Slc22a4 | protein_coding | 101985696 | Slc22a4 | ENSMUSG00000020334 | Slc22a4 | ortholog_one2one | 94.3942 | ENSG00000197208 | SLC22A4 | ortholog_one2one | 85.5335 | NA | NA | NA | NA | NA | NA | 30805 | 30805 | 6583 | 6583 |
| ENSMOCG00000016179 | 438.380749 | 0.5658109 | 0.1048483 | 0.0000000 | 0.0000000 | 102000296 | Rbp1 | protein_coding | 102000296 | Rbp1 | ENSMUSG00000046402 | Rbp1 | ortholog_one2one | 98.5185 | ENSG00000114115 | RBP1 | ortholog_one2one | 94.8148 | NA | NA | NA | NA | NA | NA | 19659 | 19659 | 5947 | 5947 |
| ENSMOCG00000007137 | 113.916905 | -0.5506326 | 0.1026396 | 0.0000000 | 0.0000000 | 101988217 | Phlda3 | protein_coding | 101988217 | Phlda3 | ENSMUSG00000041801 | Phlda3 | ortholog_one2one | 100.0000 | ENSG00000174307 | PHLDA3 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 27280 | 27280 | 23612 | 23612 |
| ENSMOCG00000003593 | 375.170680 | -0.3472087 | 0.0633591 | 0.0000000 | 0.0000000 | 102001219 | Rtkn | protein_coding | 102001219 | Rtkn | ENSMUSG00000034930 | Rtkn | ortholog_one2one | 92.5532 | ENSG00000114993 | RTKN | ortholog_one2one | 88.4752 | NA | NA | NA | NA | NA | NA | 20166 | 20166 | 6242 | 6242 |
| ENSMOCG00000015405 | 661.002422 | 0.3362744 | 0.0610551 | 0.0000000 | 0.0000000 | 101985463 | Tmtc1 | protein_coding | 101985463 | Tmtc1 | ENSMUSG00000030306 | Tmtc1 | ortholog_one2one | 92.3567 | ENSG00000133687 | TMTC1 | ortholog_one2one | 80.4671 | NA | NA | NA | NA | NA | NA | 387314 | 387314 | 83857 | 83857 |
| ENSMOCG00000007791 | 271.112587 | 0.3113841 | 0.0557965 | 0.0000000 | 0.0000000 | NA | protein_coding | NA | ENSMUSG00000110444 | Gm10033 | ortholog_one2many | 37.4536 | NA | ENSMUSG00000110444, ENSMUSG00000078877, ENSMUSG00000112160, ENSMUSG00000074165 | Gm10033, Gm14295, BC024063, Zfp788 | 37.4536, 36.5884, 34.9815, 33.869 | , , , | , , , | NA, NA, NA, NA | 378466 | 378466 | NA | NA | |||||
| ENSMOCG00000014505 | 1598.103033 | 0.2512506 | 0.0436931 | 0.0000000 | 0.0000000 | 101981956 | Wscd2 | protein_coding | 101981956 | Wscd2 | ENSMUSG00000063430 | Wscd2 | ortholog_one2one | 95.6217 | ENSG00000075035 | WSCD2 | ortholog_one2one | 90.7180 | NA | NA | NA | NA | NA | NA | 320916 | 320916 | 9671 | 9671 |
| ENSMOCG00000009993 | 67.543892 | -0.6041915 | 0.1112717 | 0.0000000 | 0.0000000 | 101999593 | Esyt1 | protein_coding | 101999593 | Esyt1 | ENSMUSG00000025366 | Esyt1 | ortholog_one2one | 93.2904 | ENSG00000139641 | ESYT1 | ortholog_one2one | 87.6838 | NA | NA | NA | NA | NA | NA | 23943 | 23943 | 23344 | 23344 |
| ENSMOCG00000001256 | 1227.043738 | 0.3270411 | 0.0592457 | 0.0000000 | 0.0000000 | 101991267 | Scmh1 | protein_coding | 101991267 | Scmh1 | ENSMUSG00000000085 | Scmh1 | ortholog_one2one | 94.7289 | ENSG00000010803 | SCMH1 | ortholog_one2one | 89.7590 | NA | NA | NA | NA | NA | NA | 29871 | 29871 | 22955 | 22955 |
| ENSMOCG00000015853 | 1380.667369 | 0.3963736 | 0.0746246 | 0.0000000 | 0.0000000 | NA | Mctp1 | protein_coding | NA | Mctp1 | ENSMUSG00000021596 | Mctp1 | ortholog_one2one | 95.8213 | ENSG00000175471 | MCTP1 | ortholog_one2one | 95.8213 | NA | NA | NA | NA | NA | NA | 78771 | 78771 | 79772 | 79772 |
| ENSMOCG00000015323 | 12.047898 | 1.1075983 | 0.2090772 | 0.0000000 | 0.0000000 | NA | Sun3 | protein_coding | NA | Sun3 | ENSMUSG00000040985 | Sun3 | ortholog_one2one | 84.6875 | ENSG00000164744 | SUN3 | ortholog_one2one | 75.9375 | NA | NA | NA | NA | NA | NA | 194974 | 194974 | 256979 | 256979 |
| ENSMOCG00000022144 | 11286.688063 | 0.2551559 | 0.0446152 | 0.0000000 | 0.0000000 | 101996959 | Sez6 | protein_coding | 101996959 | Sez6 | ENSMUSG00000000632 | Sez6 | ortholog_one2one | 95.2716 | ENSG00000063015 | SEZ6 | ortholog_one2one | 90.8451 | NA | NA | NA | NA | NA | NA | 20370 | 20370 | 124925 | 124925 |
| ENSMOCG00000012749 | 1228.211270 | -0.3523047 | 0.0650752 | 0.0000000 | 0.0000000 | 101984924 | Lypd1 | protein_coding | 101984924 | Lypd1 | ENSMUSG00000026344 | Lypd1 | ortholog_one2one | 97.1631 | ENSG00000150551 | LYPD1 | ortholog_one2one | 92.9078 | NA | NA | NA | NA | NA | NA | 72585 | 72585 | 116372 | 116372 |
| ENSMOCG00000002894 | 5915.352503 | 0.2608737 | 0.0457294 | 0.0000000 | 0.0000000 | 101994884 | Cpne5 | protein_coding | 101994884 | Cpne5 | ENSMUSG00000024008 | Cpne5 | ortholog_one2one | 98.9882 | ENSG00000124772 | CPNE5 | ortholog_one2one | 97.8078 | NA | NA | NA | NA | NA | NA | 240058 | 240058 | 57699 | 57699 |
| ENSMOCG00000016990 | 8882.232356 | 0.2849961 | 0.0505924 | 0.0000000 | 0.0000000 | 101986297 | Gng7 | protein_coding | 101986297 | Gng7 | ENSMUSG00000048240 | Gng7 | ortholog_one2one | 94.2029 | ENSG00000176533 | GNG7 | ortholog_one2one | 89.8551 | NA | NA | NA | NA | NA | NA | 14708 | 14708 | 2788 | 2788 |
| ENSMOCG00000018512 | 139.220974 | -0.6717147 | 0.1222209 | 0.0000000 | 0.0000000 | 101983969 | Scn5a | protein_coding | 101983969 | Scn5a | ENSMUSG00000032511 | Scn5a | ortholog_one2one | 97.5743 | ENSG00000183873 | SCN5A | ortholog_one2one | 93.3663 | NA | NA | NA | NA | NA | NA | 20271 | 20271 | 6331 | 6331 |
| ENSMOCG00000022095 | 161.375458 | -0.9958760 | 0.1837971 | 0.0000000 | 0.0000000 | 101987275 | Fibcd1 | protein_coding | 101987275 | Fibcd1 | ENSMUSG00000026841 | Fibcd1 | ortholog_one2one | 96.5142 | ENSG00000130720 | FIBCD1 | ortholog_one2one | 91.9390 | NA | NA | NA | NA | NA | NA | 98970 | 98970 | 84929 | 84929 |
| ENSMOCG00000013309 | 628.331601 | -1.0060964 | 0.1861487 | 0.0000000 | 0.0000000 | 101996577 | Baiap3 | protein_coding | 101996577 | Baiap3 | ENSMUSG00000047507 | Baiap3 | ortholog_one2one | 95.5652 | ENSG00000007516 | BAIAP3 | ortholog_one2one | 88.1739 | NA | NA | NA | NA | NA | NA | 545192 | 545192 | 8938 | 8938 |
| ENSMOCG00000021772 | 72.009051 | 0.7294098 | 0.1317787 | 0.0000000 | 0.0000000 | 101999311 | Zkscan7 | protein_coding | 101999311 | Zkscan7 | ENSMUSG00000063488 | Zkscan7 | ortholog_one2one | 71.6570 | ENSG00000196345 | ZKSCAN7 | ortholog_one2one | 71.0756 | NA | NA | NA | NA | NA | NA | 382118 | 382118 | 55888 | 55888 |
| ENSMOCG00000022711 | 156.746240 | 0.3262319 | 0.0598515 | 0.0000000 | 0.0000000 | 102000236 | Ska2 | protein_coding | 102000236 | Ska2 | ENSMUSG00000020492 | Ska2 | ortholog_one2one | 84.2975 | ENSG00000182628 | SKA2 | ortholog_one2one | 78.5124 | NA | NA | NA | NA | NA | NA | 66140 | 66140 | 348235 | 348235 |
| ENSMOCG00000014147 | 926.612809 | 0.4426620 | 0.0855483 | 0.0000000 | 0.0000000 | 101986098 | protein_coding | 101986098 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000007442 | 371.125212 | 0.4282405 | 0.0826671 | 0.0000000 | 0.0000001 | NA | protein_coding | NA | ENSMUSG00000060036 | Rpl3 | ortholog_one2many | 96.5261 | ENSG00000100316 | RPL3 | ortholog_one2many | 95.7816 | NA | NA | NA | NA | NA | NA | 27367 | 27367 | 6122 | 6122 | ||
| ENSMOCG00000006224 | 1190.096128 | 0.2759595 | 0.0494416 | 0.0000000 | 0.0000001 | 101995117 | Smpd3 | protein_coding | 101995117 | Smpd3 | ENSMUSG00000031906 | Smpd3 | ortholog_one2one | 97.0992 | ENSG00000103056 | SMPD3 | ortholog_one2one | 90.8397 | NA | NA | NA | NA | NA | NA | 58994 | 58994 | 55512 | 55512 |
| ENSMOCG00000019929 | 74.928745 | 0.4154156 | 0.0804645 | 0.0000000 | 0.0000001 | 101998815 | protein_coding | 101998815 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000019054 | 198.024295 | -0.3522848 | 0.0664593 | 0.0000000 | 0.0000001 | 101987733 | Nkd1 | protein_coding | 101987733 | Nkd1 | ENSMUSG00000031661 | Nkd1 | ortholog_one2one | 96.1783 | ENSG00000140807 | NKD1 | ortholog_one2one | 86.8365 | NA | NA | NA | NA | NA | NA | 93960 | 93960 | 85407 | 85407 |
| ENSMOCG00000017305 | 482.096269 | -0.2725327 | 0.0490129 | 0.0000000 | 0.0000001 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000016799 | 193.582079 | 0.2772707 | 0.0500012 | 0.0000000 | 0.0000001 | 101983572 | Dcp1b | protein_coding | 101983572 | Dcp1b | ENSMUSG00000041477 | Dcp1b | ortholog_one2one | 83.1346 | ENSG00000151065 | DCP1B | ortholog_one2one | 67.4617 | NA | NA | NA | NA | NA | NA | 319618 | 319618 | 196513 | 196513 |
| ENSMOCG00000019544 | 1342.765209 | 0.3190760 | 0.0590282 | 0.0000000 | 0.0000001 | 101979982 | Tiam2 | protein_coding | 101979982 | Tiam2 | ENSMUSG00000023800 | Tiam2 | ortholog_one2one | 90.8033 | ENSG00000146426 | TIAM2 | ortholog_one2one | 85.1572 | NA | NA | NA | NA | NA | NA | 24001 | 24001 | 26230 | 26230 |
| ENSMOCG00000019271 | 178.566982 | 0.3078914 | 0.0567445 | 0.0000000 | 0.0000001 | 101997718 | Kics2 | protein_coding | 101997718 | Kics2 | ENSMUSG00000053684 | Kics2 | ortholog_one2one | 98.4270 | ENSG00000174206 | KICS2 | ortholog_one2one | 95.0562 | NA | NA | NA | NA | NA | NA | 270802 | 270802 | 144577 | 144577 |
| ENSMOCG00000015368 | 289.424209 | 0.3536907 | 0.0673307 | 0.0000000 | 0.0000001 | 102002763 | Erap1 | protein_coding | 102002763 | Erap1 | ENSMUSG00000021583 | Erap1 | ortholog_one2one | 89.3730 | ENSG00000164307 | ERAP1 | ortholog_one2one | 85.5473 | NA | NA | NA | NA | NA | NA | 80898 | 80898 | 51752 | 51752 |
| ENSMOCG00000014110 | 605.946280 | 0.2826418 | 0.0515417 | 0.0000000 | 0.0000001 | 102000541 | Cdkl5 | protein_coding | 102000541 | Cdkl5 | ENSMUSG00000031292 | Cdkl5 | ortholog_one2one | 97.7083 | ENSG00000008086 | CDKL5 | ortholog_one2one | 95.7292 | NA | NA | NA | NA | NA | NA | 382253 | 382253 | 6792 | 6792 |
| ENSMOCG00000016979 | 345.632366 | 0.5165886 | 0.1017018 | 0.0000000 | 0.0000001 | NA | Tead4 | protein_coding | NA | Tead4 | ENSMUSG00000030353 | Tead4 | ortholog_one2one | 95.7845 | ENSG00000197905 | TEAD4 | ortholog_one2one | 94.1452 | NA | NA | NA | NA | NA | NA | 21679 | 21679 | 7004 | 7004 |
| ENSMOCG00000006707 | 445.856247 | 0.3582856 | 0.0687978 | 0.0000000 | 0.0000001 | 101979655 | Dgkh | protein_coding | 101979655 | Dgkh | ENSMUSG00000034731 | Dgkh | ortholog_one2one | 94.1227 | ENSG00000102780 | DGKH | ortholog_one2one | 91.5298 | NA | NA | NA | NA | NA | NA | 380921 | 380921 | 160851 | 160851 |
| ENSMOCG00000022557 | 757.954751 | -0.3776990 | 0.0735078 | 0.0000000 | 0.0000001 | 101984242 | Tppp3 | protein_coding | 101984242 | Tppp3 | ENSMUSG00000014846 | Tppp3 | ortholog_one2one | 98.2955 | ENSG00000159713 | TPPP3 | ortholog_one2one | 97.1591 | NA | NA | NA | NA | NA | NA | 67971 | 67971 | 51673 | 51673 |
| ENSMOCG00000017811 | 2981.585915 | 0.3173351 | 0.0595615 | 0.0000000 | 0.0000001 | 101989677 | Aqp4 | protein_coding | 101989677 | Aqp4 | ENSMUSG00000024411 | Aqp4 | ortholog_one2one | 89.4737 | ENSG00000171885 | AQP4 | ortholog_one2one | 93.8081 | NA | NA | NA | NA | NA | NA | 11829 | 11829 | 361 | 361 |
| ENSMOCG00000015958 | 17.648112 | -1.5040059 | 0.3201725 | 0.0000000 | 0.0000001 | 102002832 | Epn3 | protein_coding | 102002832 | Epn3 | ENSMUSG00000010080 | Epn3 | ortholog_one2one | 93.9873 | ENSG00000049283 | EPN3 | ortholog_one2one | 86.2342 | NA | NA | NA | NA | NA | NA | 71889 | 71889 | 55040 | 55040 |
| ENSMOCG00000021903 | 833.838065 | -0.4218273 | 0.0837807 | 0.0000000 | 0.0000001 | 102002656 | Lgi3 | protein_coding | 102002656 | Lgi3 | ENSMUSG00000033595 | Lgi3 | ortholog_one2one | 98.7085 | ENSG00000168481 | LGI3 | ortholog_one2one | 96.1255 | NA | NA | NA | NA | NA | NA | 213469 | 213469 | 203190 | 203190 |
| ENSMOCG00000018923 | 15519.563666 | 0.2669182 | 0.0487122 | 0.0000000 | 0.0000001 | 101983857 | Ppp1r1b | protein_coding | 101983857 | Ppp1r1b | ENSMUSG00000061718 | Ppp1r1b | ortholog_one2one | 89.2683 | ENSG00000131771 | PPP1R1B | ortholog_one2one | 86.8293 | NA | NA | NA | NA | NA | NA | 19049 | 19049 | 84152 | 84152 |
| ENSMOCG00000006609 | 1516.195294 | -0.5675943 | 0.1111483 | 0.0000000 | 0.0000001 | 101984712 | protein_coding | 101984712 | ENSMUSG00000032553 | Srprb | ortholog_one2one | 27.6619 | ENSG00000144867 | SRPRB | ortholog_one2one | 26.3447 | NA | NA | NA | NA | NA | NA | 20818 | 20818 | 58477 | 58477 | ||
| ENSMOCG00000019423 | 20.591628 | -1.3395976 | 0.2811631 | 0.0000000 | 0.0000001 | 101994299 | Gpc3 | protein_coding | 101994299 | Gpc3 | ENSMUSG00000055653 | Gpc3 | ortholog_one2one | 96.2003 | ENSG00000147257 | GPC3 | ortholog_one2one | 92.2280 | NA | NA | NA | NA | NA | NA | 14734 | 14734 | 2719 | 2719 |
| ENSMOCG00000008843 | 19.167354 | -1.7573455 | 0.3775183 | 0.0000000 | 0.0000001 | 101987276 | Shh | protein_coding | 101987276 | Shh | ENSMUSG00000002633 | Shh | ortholog_one2one | 94.1043 | ENSG00000164690 | SHH | ortholog_one2one | 92.7438 | NA | NA | NA | NA | NA | NA | 20423 | 20423 | 6469 | 6469 |
| ENSMOCG00000021402 | 203.259697 | -0.8118129 | 0.1517108 | 0.0000000 | 0.0000001 | 101999346 | Slc6a7 | protein_coding | 101999346 | Slc6a7 | ENSMUSG00000052026 | Slc6a7 | ortholog_one2one | 98.9011 | ENSG00000011083 | SLC6A7 | ortholog_one2one | 97.4882 | NA | NA | NA | NA | NA | NA | 240332 | 240332 | 6534 | 6534 |
| ENSMOCG00000018911 | 710.540690 | 0.2581257 | 0.0471343 | 0.0000000 | 0.0000001 | 101987700 | Kitl | protein_coding | 101987700 | Kitl | ENSMUSG00000019966 | Kitl | ortholog_one2one | 94.5256 | ENSG00000049130 | KITLG | ortholog_one2one | 81.7518 | NA | NA | NA | NA | NA | NA | 17311 | 17311 | 4254 | 4254 |
| ENSMOCG00000003694 | 90.904018 | -1.3458420 | 0.2840124 | 0.0000000 | 0.0000001 | 101999900 | Gpr165 | protein_coding | 101999900 | Gpr165 | ENSMUSG00000031210 | Gpr165 | ortholog_one2one | 81.2775 | NA | NA | NA | NA | NA | NA | NA | 76206 | 76206 | NA | NA | |||
| ENSMOCG00000011720 | 71.786360 | -0.6736692 | 0.1286141 | 0.0000000 | 0.0000001 | 101998369 | Tmem200c | protein_coding | 101998369 | Tmem200c | ENSMUSG00000095407 | Tmem200c | ortholog_one2one | 86.6878 | ENSG00000206432 | TMEM200C | ortholog_one2one | 76.0697 | NA | NA | NA | NA | NA | NA | 622645 | 622645 | 645369 | 645369 |
| ENSMOCG00000010401 | 393.462846 | 0.6631320 | 0.1270033 | 0.0000000 | 0.0000001 | 101997328 | Sncg | protein_coding | 101997328 | Sncg | ENSMUSG00000023064 | Sncg | ortholog_one2one | 75.3425 | ENSG00000173267 | SNCG | ortholog_one2one | 68.4931 | NA | NA | NA | NA | NA | NA | 20618 | 20618 | 6623 | 6623 |
| ENSMOCG00000003322 | 53.907629 | -0.8680988 | 0.1639041 | 0.0000000 | 0.0000001 | 101983916 | Tmem215 | protein_coding | 101983916 | Tmem215 | ENSMUSG00000046593 | Tmem215 | ortholog_one2one | 96.9697 | ENSG00000188133 | TMEM215 | ortholog_one2one | 92.6407 | NA | NA | NA | NA | NA | NA | 320500 | 320500 | 401498 | 401498 |
| ENSMOCG00000006613 | 775.537246 | 0.2557370 | 0.0469049 | 0.0000000 | 0.0000001 | 101984355 | Cnst | protein_coding | 101984355 | Cnst | ENSMUSG00000038949 | Cnst | ortholog_one2one | 76.9663 | ENSG00000162852 | CNST | ortholog_one2one | 69.8034 | NA | NA | NA | NA | NA | NA | 226744 | 226744 | 163882 | 163882 |
| ENSMOCG00000012807 | 136.134705 | -0.9824051 | 0.1903311 | 0.0000000 | 0.0000002 | 102001529 | Prelp | protein_coding | 102001529 | Prelp | ENSMUSG00000041577 | Prelp | ortholog_one2one | 94.4882 | ENSG00000188783 | PRELP | ortholog_one2one | 90.2887 | NA | NA | NA | NA | NA | NA | 116847 | 116847 | 5549 | 5549 |
| ENSMOCG00000014434 | 597.282759 | -0.4180142 | 0.0842926 | 0.0000000 | 0.0000002 | 102001154 | Myrf | protein_coding | 102001154 | Myrf | ENSMUSG00000036098 | Myrf | ortholog_one2one | 95.2632 | ENSG00000124920 | MYRF | ortholog_one2one | 90.4386 | NA | NA | NA | NA | NA | NA | 225908 | 225908 | 745 | 745 |
| ENSMOCG00000015234 | 620.776600 | 0.2791738 | 0.0521005 | 0.0000000 | 0.0000002 | 101993094 | Adgra3 | protein_coding | 101993094 | Adgra3 | ENSMUSG00000029090 | Adgra3 | ortholog_one2one | 95.7919 | ENSG00000152990 | ADGRA3 | ortholog_one2one | 92.8845 | NA | NA | NA | NA | NA | NA | 70693 | 70693 | 166647 | 166647 |
| ENSMOCG00000012236 | 388.904955 | 0.2667163 | 0.0495701 | 0.0000000 | 0.0000002 | NA | protein_coding | NA | ENSMUSG00000056121 | Fez2 | ortholog_one2one | 87.9397 | ENSG00000171055 | FEZ2 | ortholog_one2one | 87.9397 | NA | NA | NA | NA | NA | NA | 225020 | 225020 | 9637 | 9637 | ||
| ENSMOCG00000009288 | 463.158581 | 0.2587768 | 0.0479764 | 0.0000000 | 0.0000002 | 101989022 | Ubxn2b | protein_coding | 101989022 | Ubxn2b | ENSMUSG00000028243 | Ubxn2b | ortholog_one2one | 87.0091 | ENSG00000215114 | UBXN2B | ortholog_one2one | 85.8006 | NA | NA | NA | NA | NA | NA | 68053 | 68053 | 137886 | 137886 |
| ENSMOCG00000019437 | 668.671339 | -0.3852195 | 0.0773172 | 0.0000000 | 0.0000002 | 101993166 | Mog | protein_coding | 101993166 | Mog | ENSMUSG00000076439 | Mog | ortholog_one2one | 91.8367 | ENSG00000204655 | MOG | ortholog_one2one | 86.9388 | NA | NA | NA | NA | NA | NA | 17441 | 17441 | 4340 | 4340 |
| ENSMOCG00000008345 | 104.383257 | -0.5568709 | 0.1124821 | 0.0000000 | 0.0000002 | 101992233 | Dnai1 | protein_coding | 101992233 | Dnai1 | ENSMUSG00000061322 | Dnai1 | ortholog_one2one | 95.2518 | ENSG00000122735 | DNAI1 | ortholog_one2one | 88.0576 | NA | NA | NA | NA | NA | NA | 68922 | 68922 | 27019 | 27019 |
| ENSMOCG00000012164 | 1225.347600 | 0.2940683 | 0.0560112 | 0.0000000 | 0.0000002 | 101980913 | Rps6ka3 | protein_coding | 101980913 | Rps6ka3 | ENSMUSG00000031309 | Rps6ka3 | ortholog_one2one | 100.0000 | ENSG00000177189 | RPS6KA3 | ortholog_one2one | 99.8649 | NA | NA | NA | NA | NA | NA | 110651 | 110651 | 6197 | 6197 |
| ENSMOCG00000005385 | 59.312482 | -0.9079760 | 0.1764038 | 0.0000000 | 0.0000002 | 101983301 | Chrm3 | protein_coding | 101983301 | Chrm3 | ENSMUSG00000046159 | Chrm3 | ortholog_one2one | 96.4286 | ENSG00000133019 | CHRM3 | ortholog_one2one | 92.8571 | NA | NA | NA | NA | NA | NA | 12671 | 12671 | 1131 | 1131 |
| ENSMOCG00000012323 | 28.488895 | -0.8195699 | 0.1578126 | 0.0000000 | 0.0000002 | 101994218 | Col6a3 | protein_coding | 101994218 | Col6a3 | ENSMUSG00000048126 | Col6a3 | ortholog_one2one | 89.2923 | ENSG00000163359 | COL6A3 | ortholog_one2one | 80.4759 | NA | NA | NA | NA | NA | NA | 12835 | 12835 | 1293 | 1293 |
| ENSMOCG00000014271 | 42.734951 | -0.8477129 | 0.1635237 | 0.0000000 | 0.0000002 | 101985467 | Ttll3 | protein_coding | 101985467 | Ttll3 | ENSMUSG00000030276 | Ttll3 | ortholog_one2one | 85.3420 | ENSG00000214021 | TTLL3 | ortholog_one2one | 63.4093 | NA | NA | NA | NA | NA | NA | 101100 | 101100 | 26140 | 26140 |
| ENSMOCG00000002247 | 7103.875513 | 0.2656073 | 0.0499708 | 0.0000000 | 0.0000002 | 101999471 | Itpr1 | protein_coding | 101999471 | Itpr1 | ENSMUSG00000030102 | Itpr1 | ortholog_one2one | 99.3452 | ENSG00000150995 | ITPR1 | ortholog_one2one | 98.5085 | NA | NA | NA | NA | NA | NA | 16438 | 16438 | 3708 | 3708 |
| ENSMOCG00000018421 | 15.499574 | -1.1156969 | 0.2294320 | 0.0000000 | 0.0000002 | 101987007 | Prss50 | protein_coding | 101987007 | Prss50 | ENSMUSG00000048752 | Prss50 | ortholog_one2one | 76.6509 | ENSG00000283706 | PRSS50 | ortholog_one2one | 57.3113 | NA | NA | NA | NA | NA | NA | 235631 | 235631 | 29122 | 29122 |
| ENSMOCG00000000568 | 481.768963 | 0.2779110 | 0.0528422 | 0.0000000 | 0.0000003 | 101987397 | Ust | protein_coding | 101987397 | Ust | ENSMUSG00000047712 | Ust | ortholog_one2one | 97.5490 | ENSG00000111962 | UST | ortholog_one2one | 95.8333 | NA | NA | NA | NA | NA | NA | 338362 | 338362 | 10090 | 10090 |
| ENSMOCG00000001184 | 1579.521538 | 0.2586141 | 0.0487071 | 0.0000000 | 0.0000003 | 101994160 | Dixdc1 | protein_coding | 101994160 | Dixdc1 | ENSMUSG00000032064 | Dixdc1 | ortholog_one2one | 95.0365 | ENSG00000150764 | DIXDC1 | ortholog_one2one | 93.2847 | NA | NA | NA | NA | NA | NA | 330938 | 330938 | 85458 | 85458 |
| ENSMOCG00000009601 | 258.617767 | 0.3848314 | 0.0786103 | 0.0000000 | 0.0000003 | 101999005 | Nup210 | protein_coding | 101999005 | Nup210 | ENSMUSG00000030091 | Nup210 | ortholog_one2one | 95.0689 | ENSG00000132182 | NUP210 | ortholog_one2one | 84.5705 | NA | NA | NA | NA | NA | NA | 54563 | 54563 | 23225 | 23225 |
| ENSMOCG00000006489 | 20.180326 | -1.2049870 | 0.2564422 | 0.0000000 | 0.0000003 | 101990194 | Klk8 | protein_coding | 101990194 | Klk8 | ENSMUSG00000064023 | Klk8 | ortholog_one2one | 86.1538 | ENSG00000129455 | KLK8 | ortholog_one2one | 73.4615 | NA | NA | NA | NA | NA | NA | 259277 | 259277 | 11202 | 11202 |
| ENSMOCG00000020037 | 281.943763 | -0.2693419 | 0.0512005 | 0.0000000 | 0.0000003 | 101979922 | Mcam | protein_coding | 101979922 | Mcam | ENSMUSG00000032135 | Mcam | ortholog_one2one | 87.3652 | ENSG00000076706 | MCAM | ortholog_one2one | 77.0416 | NA | NA | NA | NA | NA | NA | 84004 | 84004 | 4162 | 4162 |
| ENSMOCG00000002975 | 130.326509 | -0.4122320 | 0.0855572 | 0.0000000 | 0.0000003 | 102000546 | Unc5b | protein_coding | 102000546 | Unc5b | ENSMUSG00000020099 | Unc5b | ortholog_one2one | 95.1374 | ENSG00000107731 | UNC5B | ortholog_one2one | 93.0233 | NA | NA | NA | NA | NA | NA | 107449 | 107449 | 219699 | 219699 |
| ENSMOCG00000006127 | 437.901046 | 0.3545674 | 0.0714812 | 0.0000000 | 0.0000003 | NA | Nin | protein_coding | NA | Nin | ENSMUSG00000021068 | Nin | ortholog_one2one | 84.3734 | ENSG00000100503 | NIN | ortholog_one2one | 78.4881 | NA | NA | NA | NA | NA | NA | 18080 | 18080 | 51199 | 51199 |
| ENSMOCG00000012578 | 202.061369 | -0.4820971 | 0.1009727 | 0.0000000 | 0.0000003 | 101981897 | Adamts4 | protein_coding | 101981897 | Adamts4 | ENSMUSG00000006403 | Adamts4 | ortholog_one2one | 94.8317 | ENSG00000158859 | ADAMTS4 | ortholog_one2one | 91.7067 | NA | NA | NA | NA | NA | NA | 240913 | 240913 | 9507 | 9507 |
| ENSMOCG00000003294 | 189.131025 | 0.3439856 | 0.0689006 | 0.0000000 | 0.0000003 | 101982319 | Zfp871 | protein_coding | 101982319 | Zfp871 | ENSMUSG00000024298 | Zfp871 | ortholog_one2one | 89.9514 | ENSG00000181896 | ZNF101 | ortholog_one2many | 28.8493 | NA | NA | NA | NA | NA | NA | 208292 | 208292 | 94039 | 94039 |
| ENSMOCG00000011104 | 389.389390 | 0.5824878 | 0.1191204 | 0.0000000 | 0.0000003 | 101990967 | Car12 | protein_coding | 101990967 | Car12 | ENSMUSG00000032373 | Car12 | ortholog_one2one | 92.0904 | ENSG00000074410 | CA12 | ortholog_one2one | 82.4859 | NA | NA | NA | NA | NA | NA | 76459 | 76459 | 771 | 771 |
| ENSMOCG00000002685 | 523.814567 | 0.2660493 | 0.0507316 | 0.0000000 | 0.0000003 | 101988300 | Wdr59 | protein_coding | 101988300 | Wdr59 | ENSMUSG00000031959 | Wdr59 | ortholog_one2one | 96.7611 | ENSG00000103091 | WDR59 | ortholog_one2one | 95.7490 | NA | NA | NA | NA | NA | NA | 319481 | 319481 | 79726 | 79726 |
| ENSMOCG00000012600 | 534.700825 | 0.2667049 | 0.0509407 | 0.0000000 | 0.0000003 | 101989661 | Arhgef18 | protein_coding | 101989661 | Arhgef18 | ENSMUSG00000004568 | Arhgef18 | ortholog_one2one | 88.0671 | ENSG00000104880 | ARHGEF18 | ortholog_one2one | 80.6706 | NA | NA | NA | NA | NA | NA | 102098 | 102098 | 23370 | 23370 |
| ENSMOCG00000021444 | 267.051939 | -0.4394084 | 0.0924748 | 0.0000000 | 0.0000004 | 101979888 | Xrcc5 | protein_coding | 101979888 | Xrcc5 | ENSMUSG00000026187 | Xrcc5 | ortholog_one2one | 78.4461 | ENSG00000079246 | XRCC5 | ortholog_one2one | 69.1729 | NA | NA | NA | NA | NA | NA | 22596 | 22596 | 7520 | 7520 |
| ENSMOCG00000014932 | 2271.213962 | 0.2599378 | 0.0496018 | 0.0000000 | 0.0000004 | 101985350 | Septin11 | protein_coding | 101985350 | Septin11 | ENSMUSG00000058013 | Septin11 | ortholog_one2one | 100.0000 | ENSG00000138758 | SEPTIN11 | ortholog_one2one | 98.3759 | NA | NA | NA | NA | NA | NA | 52398 | 52398 | 55752 | 55752 |
| ENSMOCG00000001148 | 147.790316 | -0.4397014 | 0.0926553 | 0.0000000 | 0.0000004 | 101987059 | Qpct | protein_coding | 101987059 | Qpct | ENSMUSG00000024084 | Qpct | ortholog_one2one | 91.4127 | ENSG00000115828 | QPCT | ortholog_one2one | 83.1025 | NA | NA | NA | NA | NA | NA | 70536 | 70536 | 25797 | 25797 |
| ENSMOCG00000013639 | 289.178555 | 0.3111080 | 0.0614877 | 0.0000000 | 0.0000004 | 106144047 | Gabrg3 | protein_coding | 106144047 | Gabrg3 | ENSMUSG00000055026 | Gabrg3 | ortholog_one2one | 98.0728 | ENSG00000182256 | GABRG3 | ortholog_one2one | 94.6467 | NA | NA | NA | NA | NA | NA | 14407 | 14407 | 2567 | 2567 |
| ENSMOCG00000016536 | 860.702969 | 0.2960977 | 0.0580076 | 0.0000000 | 0.0000004 | 101989587 | Rims1 | protein_coding | 101989587 | Rims1 | ENSMUSG00000041670 | Rims1 | ortholog_one2one | 94.8479 | ENSG00000079841 | RIMS1 | ortholog_one2one | 91.5580 | NA | NA | NA | NA | NA | NA | 116837 | 116837 | 22999 | 22999 |
| ENSMOCG00000016908 | 252.728100 | 0.5814584 | 0.1207155 | 0.0000000 | 0.0000004 | 101979704 | Ak9 | protein_coding | 101979704 | Ak9 | ENSMUSG00000091415 | Ak9 | ortholog_one2one | 80.6776 | ENSG00000155085 | AK9 | ortholog_one2one | 74.2192 | NA | NA | NA | NA | NA | NA | 633979 | 633979 | 221264 | 221264 |
| ENSMOCG00000013478 | 2376.416350 | 0.2721375 | 0.0527661 | 0.0000000 | 0.0000005 | 101999413 | Ypel2 | protein_coding | 101999413 | Ypel2 | ENSMUSG00000018427 | Ypel2 | ortholog_one2one | 100.0000 | ENSG00000175155 | YPEL2 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 77864 | 77864 | 388403 | 388403 |
| ENSMOCG00000001925 | 362.888921 | -0.3025252 | 0.0598103 | 0.0000000 | 0.0000005 | 101989891 | Cdkl1 | protein_coding | 101989891 | Cdkl1 | ENSMUSG00000020990 | Cdkl1 | ortholog_one2one | 95.1705 | ENSG00000100490 | CDKL1 | ortholog_one2one | 90.3409 | NA | NA | NA | NA | NA | NA | 71091 | 71091 | 8814 | 8814 |
| ENSMOCG00000018342 | 900.931038 | -0.4524309 | 0.0966908 | 0.0000000 | 0.0000005 | 101999818 | Bcat1 | protein_coding | 101999818 | Bcat1 | ENSMUSG00000030268 | Bcat1 | ortholog_one2one | 86.6962 | ENSG00000060982 | BCAT1 | ortholog_one2one | 72.2838 | NA | NA | NA | NA | NA | NA | 12035 | 12035 | 586 | 586 |
| ENSMOCG00000005700 | 1178.107686 | 0.9461462 | 0.1921114 | 0.0000000 | 0.0000005 | NA | protein_coding | NA | NA | ENSG00000111640 | GAPDH | ortholog_one2many | 92.1922 | NA | NA | NA | NA | NA | NA | NA | NA | 2597 | 2597 | |||||
| ENSMOCG00000012337 | 528.957693 | -0.2868082 | 0.0563483 | 0.0000000 | 0.0000005 | 102002227 | Hebp1 | protein_coding | 102002227 | Hebp1 | ENSMUSG00000042770 | Hebp1 | ortholog_one2one | 94.7368 | ENSG00000013583 | HEBP1 | ortholog_one2one | 88.4211 | NA | NA | NA | NA | NA | NA | 15199 | 15199 | 50865 | 50865 |
| ENSMOCG00000010974 | 85.290160 | -0.4705751 | 0.1009588 | 0.0000000 | 0.0000005 | 101992158 | Pcdh18 | protein_coding | 101992158 | Pcdh18 | ENSMUSG00000037892 | Pcdh18 | ortholog_one2one | 96.8254 | ENSG00000189184 | PCDH18 | ortholog_one2one | 92.8571 | NA | NA | NA | NA | NA | NA | 73173 | 73173 | 54510 | 54510 |
| ENSMOCG00000004048 | 151.901673 | -0.6496036 | 0.1332350 | 0.0000000 | 0.0000005 | 101986244 | protein_coding | 101986244 | ENSMUSG00000027890 | Gstm4 | ortholog_one2many | 91.3043 | ENSG00000168765 | GSTM4 | ortholog_one2many | 86.9565 | NA | NA | NA | NA | NA | NA | 14865 | 14865 | 2948 | 2948 | ||
| ENSMOCG00000014116 | 65.810750 | -0.5925024 | 0.1239120 | 0.0000000 | 0.0000005 | 101993648 | Sfrp1 | protein_coding | 101993648 | Sfrp1 | ENSMUSG00000031548 | Sfrp1 | ortholog_one2one | 97.1338 | ENSG00000104332 | SFRP1 | ortholog_one2one | 94.2675 | NA | NA | NA | NA | NA | NA | 20377 | 20377 | 6422 | 6422 |
| ENSMOCG00000016412 | 435.278265 | -0.3781549 | 0.0795703 | 0.0000000 | 0.0000006 | 102000948 | Tmeff2 | protein_coding | 102000948 | Tmeff2 | ENSMUSG00000026109 | Tmeff2 | ortholog_one2one | 98.9305 | ENSG00000144339 | TMEFF2 | ortholog_one2one | 98.3957 | NA | NA | NA | NA | NA | NA | 56363 | 56363 | 23671 | 23671 |
| ENSMOCG00000004134 | 334.100603 | 0.2818379 | 0.0555151 | 0.0000000 | 0.0000006 | 102000470 | B3glct | protein_coding | 102000470 | B3glct | ENSMUSG00000051950 | B3glct | ortholog_one2one | 89.3661 | ENSG00000187676 | B3GLCT | ortholog_one2one | 85.4806 | NA | NA | NA | NA | NA | NA | 381694 | 381694 | 145173 | 145173 |
| ENSMOCG00000012468 | 389.539640 | -0.3159836 | 0.0637344 | 0.0000000 | 0.0000006 | 101983143 | Tjp2 | protein_coding | 101983143 | Tjp2 | ENSMUSG00000024812 | Tjp2 | ortholog_one2one | 93.7069 | ENSG00000119139 | TJP2 | ortholog_one2one | 87.1552 | NA | NA | NA | NA | NA | NA | 21873 | 21873 | 9414 | 9414 |
| ENSMOCG00000013021 | 93.341713 | -0.6673671 | 0.1373571 | 0.0000000 | 0.0000006 | 101989187 | Amigo2 | protein_coding | 101989187 | Amigo2 | ENSMUSG00000048218 | Amigo2 | ortholog_one2one | 91.8919 | ENSG00000139211 | AMIGO2 | ortholog_one2one | 87.6448 | NA | NA | NA | NA | NA | NA | 105827 | 105827 | 347902 | 347902 |
| ENSMOCG00000002500 | 138.867195 | -0.5238942 | 0.1128220 | 0.0000000 | 0.0000006 | 101993402 | Klhdc8a | protein_coding | 101993402 | Klhdc8a | ENSMUSG00000042115 | Klhdc8a | ortholog_one2one | 98.2857 | ENSG00000162873 | KLHDC8A | ortholog_one2one | 96.2857 | NA | NA | NA | NA | NA | NA | 213417 | 213417 | 55220 | 55220 |
| ENSMOCG00000012767 | 251.369889 | 0.2716380 | 0.0534682 | 0.0000000 | 0.0000006 | NA | Usp45 | protein_coding | NA | Usp45 | ENSMUSG00000040455 | Usp45 | ortholog_one2one | 80.9170 | ENSG00000123552 | USP45 | ortholog_one2one | 71.4994 | NA | NA | NA | NA | NA | NA | 77593 | 77593 | 85015 | 85015 |
| ENSMOCG00000001513 | 84.077975 | -0.4059890 | 0.0872506 | 0.0000000 | 0.0000007 | 101988267 | C2cd4c | protein_coding | 101988267 | C2cd4c | ENSMUSG00000045912 | C2cd4c | ortholog_one2one | 95.9716 | ENSG00000183186 | C2CD4C | ortholog_one2one | 90.9953 | NA | NA | NA | NA | NA | NA | 237397 | 237397 | 126567 | 126567 |
| ENSMOCG00000008791 | 126.914385 | -0.4655169 | 0.1015170 | 0.0000000 | 0.0000007 | 101982302 | Fbln1 | protein_coding | 101982302 | Fbln1 | ENSMUSG00000006369 | Fbln1 | ortholog_one2one | 93.1526 | ENSG00000077942 | FBLN1 | ortholog_one2one | 85.8773 | NA | NA | NA | NA | NA | NA | 14114 | 14114 | 2192 | 2192 |
| ENSMOCG00000023018 | 326.242324 | -0.2862551 | 0.0571088 | 0.0000000 | 0.0000007 | 101994312 | Fxyd7 | protein_coding | 101994312 | Fxyd7 | ENSMUSG00000036578 | Fxyd7 | ortholog_one2one | 96.2500 | ENSG00000221946 | FXYD7 | ortholog_one2one | 90.0000 | NA | NA | NA | NA | NA | NA | 57780 | 57780 | 53822 | 53822 |
| ENSMOCG00000016983 | 1543.566894 | 0.2886597 | 0.0577426 | 0.0000000 | 0.0000007 | 101978993 | Kctd13 | protein_coding | 101978993 | Kctd13 | ENSMUSG00000030685 | Kctd13 | ortholog_one2one | 97.2644 | ENSG00000174943 | KCTD13 | ortholog_one2one | 95.4407 | NA | NA | NA | NA | NA | NA | 233877 | 233877 | 253980 | 253980 |
| ENSMOCG00000001982 | 115.566400 | -0.4376149 | 0.0955854 | 0.0000000 | 0.0000008 | 101981639 | Prkcq | protein_coding | 101981639 | Prkcq | ENSMUSG00000026778 | Prkcq | ortholog_one2one | 96.6245 | ENSG00000065675 | PRKCQ | ortholog_one2one | 94.7961 | NA | NA | NA | NA | NA | NA | 18761 | 18761 | 5588 | 5588 |
| ENSMOCG00000015427 | 721.162207 | 0.2864331 | 0.0577568 | 0.0000000 | 0.0000009 | 101981836 | Fzd3 | protein_coding | 101981836 | Fzd3 | ENSMUSG00000007989 | Fzd3 | ortholog_one2one | 98.6487 | ENSG00000104290 | FZD3 | ortholog_one2one | 97.7477 | NA | NA | NA | NA | NA | NA | 14365 | 14365 | 7976 | 7976 |
| ENSMOCG00000022952 | 20.709951 | 0.8011486 | 0.1654732 | 0.0000000 | 0.0000009 | 101997165 | Anxa13 | protein_coding | 101997165 | Anxa13 | ENSMUSG00000055114 | Anxa13 | ortholog_one2one | 87.8505 | ENSG00000104537 | ANXA13 | ortholog_one2one | 84.1122 | NA | NA | NA | NA | NA | NA | 69787 | 69787 | 312 | 312 |
| ENSMOCG00000012554 | 58.130275 | 1.5027303 | 0.3614902 | 0.0000000 | 0.0000009 | NA | protein_coding | NA | ENSMUSG00000054046 | Klk13 | ortholog_one2one | 95.3271 | ENSG00000167759 | KLK13 | ortholog_one2one | 82.2430 | NA | NA | NA | NA | NA | NA | 626834 | 626834 | 26085 | 26085 | ||
| ENSMOCG00000019829 | 156.212162 | -0.5185732 | 0.1140703 | 0.0000000 | 0.0000009 | 101989284 | P4ha3 | protein_coding | 101989284 | P4ha3 | ENSMUSG00000051048 | P4ha3 | ortholog_one2one | 81.8702 | ENSG00000149380 | P4HA3 | ortholog_one2one | 79.0076 | NA | NA | NA | NA | NA | NA | 320452 | 320452 | 283208 | 283208 |
| ENSMOCG00000018492 | 275.387620 | 0.3351964 | 0.0703642 | 0.0000000 | 0.0000010 | 101985252 | Msh3 | protein_coding | 101985252 | Msh3 | ENSMUSG00000014850 | Msh3 | ortholog_one2one | 88.2784 | ENSG00000113318 | MSH3 | ortholog_one2one | 81.6850 | NA | NA | NA | NA | NA | NA | 17686 | 17686 | 4437 | 4437 |
| ENSMOCG00000012799 | 5328.120719 | 0.3179011 | 0.0658831 | 0.0000000 | 0.0000010 | 101990083 | Strip2 | protein_coding | 101990083 | Strip2 | ENSMUSG00000039629 | Strip2 | ortholog_one2one | 96.8937 | ENSG00000128578 | STRIP2 | ortholog_one2one | 95.4600 | NA | NA | NA | NA | NA | NA | 320609 | 320609 | 57464 | 57464 |
| ENSMOCG00000018806 | 487.340018 | -0.2681898 | 0.0537571 | 0.0000000 | 0.0000010 | NA | protein_coding | NA | ENSMUSG00000048537 | Phldb1 | ortholog_one2many | 90.9502 | ENSG00000019144 | PHLDB1 | ortholog_one2many | 89.5928 | NA | NA | NA | NA | NA | NA | 102693 | 102693 | 23187 | 23187 | ||
| ENSMOCG00000017735 | 2868.223532 | 0.2895579 | 0.0589009 | 0.0000000 | 0.0000010 | 101980073 | Adora2a | protein_coding | 101980073 | Adora2a | ENSMUSG00000020178 | Adora2a | ortholog_one2one | 91.4216 | ENSG00000128271 | ADORA2A | ortholog_one2one | 83.3333 | NA | NA | NA | NA | NA | NA | 11540 | 11540 | 135 | 135 |
| ENSMOCG00000015965 | 537.664845 | -0.3985399 | 0.0873839 | 0.0000000 | 0.0000010 | 102000262 | Ugt8a | protein_coding | 102000262 | Ugt8a | ENSMUSG00000032854 | Ugt8a | ortholog_one2one | 96.1183 | ENSG00000174607 | UGT8 | ortholog_one2one | 94.0850 | NA | NA | NA | NA | NA | NA | 22239 | 22239 | 7368 | 7368 |
| ENSMOCG00000016563 | 42.992141 | 0.5535449 | 0.1214505 | 0.0000000 | 0.0000010 | NA | Mxra8 | protein_coding | NA | Mxra8 | ENSMUSG00000029070 | Mxra8 | ortholog_one2one | 83.1839 | ENSG00000162576 | MXRA8 | ortholog_one2one | 75.3363 | NA | NA | NA | NA | NA | NA | 74761 | 74761 | 54587 | 54587 |
| ENSMOCG00000002818 | 52.532667 | -0.7327131 | 0.1532318 | 0.0000000 | 0.0000011 | 101983183 | Cpne9 | protein_coding | 101983183 | Cpne9 | ENSMUSG00000030270 | Cpne9 | ortholog_one2one | 98.9150 | ENSG00000144550 | CPNE9 | ortholog_one2one | 98.3725 | NA | NA | NA | NA | NA | NA | 211232 | 211232 | 151835 | 151835 |
| ENSMOCG00000011913 | 43.854652 | -0.7939775 | 0.1652921 | 0.0000000 | 0.0000011 | 101980139 | Nkx6-2 | protein_coding | 101980139 | Nkx6-2 | ENSMUSG00000041309 | Nkx6-2 | ortholog_one2one | 97.8339 | ENSG00000148826 | NKX6-2 | ortholog_one2one | 96.0289 | NA | NA | NA | NA | NA | NA | 14912 | 14912 | 84504 | 84504 |
| ENSMOCG00000020453 | 837.392094 | 0.2533529 | 0.0505476 | 0.0000000 | 0.0000011 | 101988161 | Kcnq5 | protein_coding | 101988161 | Kcnq5 | ENSMUSG00000028033 | Kcnq5 | ortholog_one2one | 97.6842 | ENSG00000185760 | KCNQ5 | ortholog_one2one | 94.4211 | NA | NA | NA | NA | NA | NA | 226922 | 226922 | 56479 | 56479 |
| ENSMOCG00000015813 | 768.364600 | -0.3290211 | 0.0691650 | 0.0000000 | 0.0000011 | 101995311 | Mast1 | protein_coding | 101995311 | Mast1 | ENSMUSG00000053693 | Mast1 | ortholog_one2one | 97.5796 | ENSG00000105613 | MAST1 | ortholog_one2one | 94.3949 | NA | NA | NA | NA | NA | NA | 56527 | 56527 | 22983 | 22983 |
| ENSMOCG00000002444 | 81.948210 | -0.6633343 | 0.1411526 | 0.0000000 | 0.0000011 | 101988373 | Glp1r | protein_coding | 101988373 | Glp1r | ENSMUSG00000024027 | Glp1r | ortholog_one2one | 97.1922 | ENSG00000112164 | GLP1R | ortholog_one2one | 93.5205 | NA | NA | NA | NA | NA | NA | 14652 | 14652 | 2740 | 2740 |
| ENSMOCG00000010721 | 149.791587 | -0.3078630 | 0.0637772 | 0.0000000 | 0.0000011 | 101987127 | Hmgcl | protein_coding | 101987127 | Hmgcl | ENSMUSG00000028672 | Hmgcl | ortholog_one2one | 80.5085 | ENSG00000117305 | HMGCL | ortholog_one2one | 77.9661 | NA | NA | NA | NA | NA | NA | 15356 | 15356 | 3155 | 3155 |
| ENSMOCG00000016113 | 159.193629 | -0.4134845 | 0.0918688 | 0.0000000 | 0.0000012 | 101984424 | Cpne7 | protein_coding | 101984424 | Cpne7 | ENSMUSG00000034796 | Cpne7 | ortholog_one2one | 98.2014 | ENSG00000178773 | CPNE7 | ortholog_one2one | 89.2086 | NA | NA | NA | NA | NA | NA | 102278 | 102278 | 27132 | 27132 |
| ENSMOCG00000013657 | 87.581392 | -0.4466740 | 0.1001235 | 0.0000000 | 0.0000012 | 101991209 | Grhpr | protein_coding | 101991209 | Grhpr | ENSMUSG00000035637 | Grhpr | ortholog_one2one | 92.9878 | ENSG00000137106 | GRHPR | ortholog_one2one | 85.0610 | NA | NA | NA | NA | NA | NA | 76238 | 76238 | 9380 | 9380 |
| ENSMOCG00000005836 | 69.307838 | -0.5465103 | 0.1211943 | 0.0000000 | 0.0000012 | 101998095 | S1pr5 | protein_coding | 101998095 | S1pr5 | ENSMUSG00000045087 | S1pr5 | ortholog_one2one | 94.5000 | ENSG00000180739 | S1PR5 | ortholog_one2one | 85.0000 | NA | NA | NA | NA | NA | NA | 94226 | 94226 | 53637 | 53637 |
| ENSMOCG00000021823 | 698.176095 | 0.2519279 | 0.0505633 | 0.0000000 | 0.0000012 | 102002834 | Kcnj2 | protein_coding | 102002834 | Kcnj2 | ENSMUSG00000041695 | Kcnj2 | ortholog_one2one | 99.2974 | ENSG00000123700 | KCNJ2 | ortholog_one2one | 99.2974 | NA | NA | NA | NA | NA | NA | 16518 | 16518 | 3759 | 3759 |
| ENSMOCG00000019601 | 14.777874 | 1.0715640 | 0.2380316 | 0.0000000 | 0.0000012 | 101992715 | Fmo1 | protein_coding | 101992715 | Fmo1 | ENSMUSG00000040181 | Fmo1 | ortholog_one2one | 91.9173 | ENSG00000010932 | FMO1 | ortholog_one2one | 84.2105 | NA | NA | NA | NA | NA | NA | 14261 | 14261 | 2326 | 2326 |
| ENSMOCG00000009810 | 897.091583 | -0.5607153 | 0.1243434 | 0.0000000 | 0.0000013 | 101989536 | protein_coding | 101989536 | ENSMUSG00000032517 | Mobp | ortholog_one2one | 88.8889 | ENSG00000168314 | MOBP | ortholog_one2one | 86.4198 | NA | NA | NA | NA | NA | NA | 17433 | 17433 | 4336 | 4336 | ||
| ENSMOCG00000013784 | 128.180361 | -0.7167445 | 0.1525519 | 0.0000000 | 0.0000014 | NA | Gsta4 | protein_coding | NA | Gsta4 | ENSMUSG00000032348 | Gsta4 | ortholog_one2one | 87.8378 | NA | NA | NA | NA | NA | NA | NA | 14860 | 14860 | NA | NA | |||
| ENSMOCG00000019997 | 7951.669144 | -0.3126974 | 0.0657414 | 0.0000000 | 0.0000014 | 101995578 | protein_coding | 101995578 | ENSMUSG00000027523 | Gnas | ortholog_one2one | 92.8934 | ENSG00000087460 | GNAS | ortholog_one2one | 99.4924 | NA | NA | NA | NA | NA | NA | 14683 | 14683 | 2778 | 2778 | ||
| ENSMOCG00000006627 | 38.029962 | -0.7309287 | 0.1558396 | 0.0000000 | 0.0000015 | 102000810 | protein_coding | 102000810 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000001590 | 13.635977 | -1.3441980 | 0.3266183 | 0.0000000 | 0.0000015 | 101980451 | Spag17 | protein_coding | 101980451 | Spag17 | ENSMUSG00000027867 | Spag17 | ortholog_one2one | 81.2906 | ENSG00000155761 | SPAG17 | ortholog_one2one | 72.6721 | NA | NA | NA | NA | NA | NA | 74362 | 74362 | 200162 | 200162 |
| ENSMOCG00000022590 | 157.642038 | -0.4423886 | 0.1003221 | 0.0000000 | 0.0000015 | 101982081 | Aspa | protein_coding | 101982081 | Aspa | ENSMUSG00000020774 | Aspa | ortholog_one2one | 90.0641 | ENSG00000108381 | ASPA | ortholog_one2one | 88.4615 | NA | NA | NA | NA | NA | NA | 11484 | 11484 | 443 | 443 |
| ENSMOCG00000005557 | 117.428216 | -0.9159436 | 0.1975738 | 0.0000001 | 0.0000016 | 101987899 | protein_coding | 101987899 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000003182 | 18.369474 | -0.7748990 | 0.1653910 | 0.0000001 | 0.0000016 | 101988315 | Spag1 | protein_coding | 101988315 | Spag1 | ENSMUSG00000037617 | Spag1 | ortholog_one2one | 79.6892 | ENSG00000104450 | SPAG1 | ortholog_one2one | 70.2553 | NA | NA | NA | NA | NA | NA | 26942 | 26942 | 6674 | 6674 |
| ENSMOCG00000009114 | 84.264008 | 0.3508631 | 0.0764743 | 0.0000001 | 0.0000016 | 101980282 | Rad18 | protein_coding | 101980282 | Rad18 | ENSMUSG00000030254 | Rad18 | ortholog_one2one | 80.1217 | ENSG00000070950 | RAD18 | ortholog_one2one | 70.5882 | NA | NA | NA | NA | NA | NA | 58186 | 58186 | 56852 | 56852 |
| ENSMOCG00000021718 | 52.775736 | -0.5065918 | 0.1152347 | 0.0000001 | 0.0000016 | 101982741 | Mettl8 | protein_coding | 101982741 | Mettl8 | ENSMUSG00000041975 | Mettl8 | ortholog_one2one | 85.5297 | ENSG00000123600 | METTL8 | ortholog_one2one | 76.2274 | NA | NA | NA | NA | NA | NA | 228019 | 228019 | 79828 | 79828 |
| ENSMOCG00000021100 | 62.065607 | 0.8992837 | 0.1943261 | 0.0000001 | 0.0000017 | 101982126 | Pde6b | protein_coding | 101982126 | Pde6b | ENSMUSG00000029491 | Pde6b | ortholog_one2one | 97.1963 | ENSG00000133256 | PDE6B | ortholog_one2one | 92.2897 | NA | NA | NA | NA | NA | NA | 18587 | 18587 | 5158 | 5158 |
| ENSMOCG00000019475 | 1189.207000 | 0.9342959 | 0.2034053 | 0.0000001 | 0.0000017 | NA | protein_coding | NA | NA | ENSG00000111640 | GAPDH | ortholog_one2many | 93.5385 | NA | NA | NA | NA | NA | NA | NA | NA | 2597 | 2597 | |||||
| ENSMOCG00000011385 | 64.911111 | -0.5329017 | 0.1209195 | 0.0000001 | 0.0000017 | 101981605 | Morc4 | protein_coding | 101981605 | Morc4 | ENSMUSG00000031434 | Morc4 | ortholog_one2one | 87.2570 | ENSG00000133131 | MORC4 | ortholog_one2one | 84.3413 | NA | NA | NA | NA | NA | NA | 75746 | 75746 | 79710 | 79710 |
| ENSMOCG00000020811 | 112.781153 | -0.9623660 | 0.2114988 | 0.0000001 | 0.0000018 | 101995289 | Calcr | protein_coding | 101995289 | Calcr | ENSMUSG00000023964 | Calcr | ortholog_one2one | 74.0741 | ENSG00000004948 | CALCR | ortholog_one2one | 63.8889 | NA | NA | NA | NA | NA | NA | 12311 | 12311 | 799 | 799 |
| ENSMOCG00000001528 | 86.593676 | -2.3109523 | 0.6011852 | 0.0000001 | 0.0000018 | NA | protein_coding | NA | ENSMUSG00000039001 | Rps21 | ortholog_one2many | 93.0233 | ENSG00000171858 | RPS21 | ortholog_one2many | 95.3488 | NA | NA | NA | NA | NA | NA | 66481 | 66481 | 6227 | 6227 | ||
| ENSMOCG00000007877 | 102.834021 | -0.3168107 | 0.0677883 | 0.0000001 | 0.0000018 | 101997916 | Thoc6 | protein_coding | 101997916 | Thoc6 | ENSMUSG00000041319 | Thoc6 | ortholog_one2one | 96.4809 | ENSG00000131652 | THOC6 | ortholog_one2one | 93.8416 | NA | NA | NA | NA | NA | NA | 386612 | 386612 | 79228 | 79228 |
| ENSMOCG00000017377 | 53.466733 | -0.5007247 | 0.1149858 | 0.0000001 | 0.0000019 | 101987709 | Rftn1 | protein_coding | 101987709 | Rftn1 | ENSMUSG00000039316 | Rftn1 | ortholog_one2one | 83.7887 | ENSG00000131378 | RFTN1 | ortholog_one2one | 72.1311 | NA | NA | NA | NA | NA | NA | 76438 | 76438 | 23180 | 23180 |
| ENSMOCG00000019353 | 774.333052 | -0.2915290 | 0.0612843 | 0.0000001 | 0.0000019 | 101990759 | Gas6 | protein_coding | 101990759 | Gas6 | ENSMUSG00000031451 | Gas6 | ortholog_one2one | 91.6914 | ENSG00000183087 | GAS6 | ortholog_one2one | 82.7893 | NA | NA | NA | NA | NA | NA | 14456 | 14456 | 2621 | 2621 |
| ENSMOCG00000011686 | 169.337960 | -0.5858830 | 0.1320203 | 0.0000001 | 0.0000019 | 101993921 | Lhx8 | protein_coding | 101993921 | Lhx8 | ENSMUSG00000096225 | Lhx8 | ortholog_one2one | 98.9101 | ENSG00000162624 | LHX8 | ortholog_one2one | 86.9210 | NA | NA | NA | NA | NA | NA | 16875 | 16875 | 431707 | 431707 |
| ENSMOCG00000013023 | 790.751492 | 0.3727136 | 0.0836764 | 0.0000001 | 0.0000021 | 101995761 | Adcy1 | protein_coding | 101995761 | Adcy1 | ENSMUSG00000020431 | Adcy1 | ortholog_one2one | 85.8670 | ENSG00000164742 | ADCY1 | ortholog_one2one | 80.4038 | NA | NA | NA | NA | NA | NA | 432530 | 432530 | 107 | 107 |
| ENSMOCG00000019811 | 19.116799 | -0.9598147 | 0.2136796 | 0.0000001 | 0.0000022 | NA | Mmel1 | protein_coding | NA | Mmel1 | ENSMUSG00000058183 | Mmel1 | ortholog_one2one | 81.8064 | ENSG00000142606 | MMEL1 | ortholog_one2one | 81.8064 | NA | NA | NA | NA | NA | NA | 27390 | 27390 | 79258 | 79258 |
| ENSMOCG00000019523 | 36.974875 | -0.5482485 | 0.1260070 | 0.0000001 | 0.0000023 | NA | D7Ertd443e | protein_coding | NA | D7Ertd443e | ENSMUSG00000030994 | D7Ertd443e | ortholog_one2one | 79.7688 | ENSG00000154493 | C10orf90 | ortholog_one2one | 65.1734 | NA | NA | NA | NA | NA | NA | 71007 | 71007 | 118611 | 118611 |
| ENSMOCG00000016081 | 1888.246551 | 0.2899030 | 0.0615831 | 0.0000001 | 0.0000024 | 101998372 | Spock3 | protein_coding | 101998372 | Spock3 | ENSMUSG00000054162 | Spock3 | ortholog_one2one | 86.3861 | ENSG00000196104 | SPOCK3 | ortholog_one2one | 80.9406 | NA | NA | NA | NA | NA | NA | 72902 | 72902 | 50859 | 50859 |
| ENSMOCG00000000462 | 9.854156 | -1.8226280 | 0.4813365 | 0.0000001 | 0.0000024 | 101985262 | protein_coding | 101985262 | ENSMUSG00000104713 | Gbp6 | ortholog_many2many | 82.0976 | ENSG00000183347 | GBP6 | ortholog_one2many | 77.2152 | ENSMUSG00000104713, ENSMUSG00000105096, ENSMUSG00000029298, ENSMUSG00000092021, ENSMUSG00000079363, ENSMUSG00000034438 | Gbp6, Gbp10, Gbp9, Gbp11, Gbp4, Gbp8 | 82.0976, 81.9168, 81.5552, 81.0127, 77.7577, 69.0778 | ENSG00000183347, ENSG00000183347, ENSG00000183347, ENSG00000183347, ENSG00000183347, ENSG00000183347 | GBP6, GBP6, GBP6, GBP6, GBP6, GBP6 | 77.2152, 77.2152, 77.2152, 77.2152, 77.2152, 77.2152 | 100702 | 100702 | 163351 | 163351 | ||
| ENSMOCG00000015042 | 405.007422 | -0.2851379 | 0.0604484 | 0.0000001 | 0.0000025 | 102001866 | Grip2 | protein_coding | 102001866 | Grip2 | ENSMUSG00000030098 | Grip2 | ortholog_one2one | 96.5484 | ENSG00000144596 | GRIP2 | ortholog_one2one | 87.8236 | NA | NA | NA | NA | NA | NA | 243547 | 243547 | 80852 | 80852 |
| ENSMOCG00000014752 | 62.628148 | -0.4745934 | 0.1110808 | 0.0000001 | 0.0000025 | 101983433 | protein_coding | 101983433 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000019265 | 42.313179 | 0.6990727 | 0.1550419 | 0.0000001 | 0.0000025 | 101990597 | AU021092 | protein_coding | 101990597 | AU021092 | ENSMUSG00000051669 | AU021092 | ortholog_one2one | 84.6154 | ENSG00000153446 | C16orf89 | ortholog_one2one | 68.4066 | NA | NA | NA | NA | NA | NA | 239691 | 239691 | 146556 | 146556 |
| ENSMOCG00000015929 | 244.202686 | -0.3958526 | 0.0911512 | 0.0000001 | 0.0000026 | 101980780 | Arhgdig | protein_coding | 101980780 | Arhgdig | ENSMUSG00000073433 | Arhgdig | ortholog_one2one | 92.4444 | ENSG00000242173 | ARHGDIG | ortholog_one2one | 82.2222 | NA | NA | NA | NA | NA | NA | 14570 | 14570 | 398 | 398 |
| ENSMOCG00000016075 | 69.713332 | -0.4767179 | 0.1117831 | 0.0000001 | 0.0000026 | 101979013 | Tnfaip8 | protein_coding | 101979013 | Tnfaip8 | ENSMUSG00000062210 | Tnfaip8 | ortholog_one2one | 97.1698 | ENSG00000145779 | TNFAIP8 | ortholog_one2one | 87.2642 | NA | NA | NA | NA | NA | NA | 106869 | 106869 | 25816 | 25816 |
| ENSMOCG00000019711 | 469.952721 | -0.3122304 | 0.0679729 | 0.0000001 | 0.0000028 | 101991510 | protein_coding | 101991510 | ENSMUSG00000034751 | Mast4 | ortholog_one2one | 96.9167 | ENSG00000069020 | MAST4 | ortholog_one2one | 94.8333 | NA | NA | NA | NA | NA | NA | 328329 | 328329 | 375449 | 375449 | ||
| ENSMOCG00000001011 | 705.917341 | 0.2887856 | 0.0618993 | 0.0000001 | 0.0000029 | 101983369 | Prkch | protein_coding | 101983369 | Prkch | ENSMUSG00000021108 | Prkch | ortholog_one2one | 98.9751 | ENSG00000027075 | PRKCH | ortholog_one2one | 97.8038 | NA | NA | NA | NA | NA | NA | 18755 | 18755 | 5583 | 5583 |
| ENSMOCG00000002078 | 12.916778 | -0.9622422 | 0.2185925 | 0.0000001 | 0.0000029 | 102001582 | Gchfr | protein_coding | 102001582 | Gchfr | ENSMUSG00000046814 | Gchfr | ortholog_one2one | 92.8571 | ENSG00000137880 | GCHFR | ortholog_one2one | 91.6667 | NA | NA | NA | NA | NA | NA | 320415 | 320415 | 2644 | 2644 |
| ENSMOCG00000020738 | 12.002783 | -1.3987603 | 0.3619678 | 0.0000001 | 0.0000030 | 101979773 | Lipg | protein_coding | 101979773 | Lipg | ENSMUSG00000053846 | Lipg | ortholog_one2one | 80.4000 | ENSG00000101670 | LIPG | ortholog_one2one | 75.8000 | NA | NA | NA | NA | NA | NA | 16891 | 16891 | 9388 | 9388 |
| ENSMOCG00000012510 | 28.175807 | 0.6246195 | 0.1428818 | 0.0000001 | 0.0000031 | 101990013 | Pm20d1 | protein_coding | 101990013 | Pm20d1 | ENSMUSG00000042251 | Pm20d1 | ortholog_one2one | 84.8907 | ENSG00000162877 | PM20D1 | ortholog_one2one | 73.9563 | NA | NA | NA | NA | NA | NA | 212933 | 212933 | 148811 | 148811 |
| ENSMOCG00000009804 | 273.475004 | -0.3080667 | 0.0672185 | 0.0000001 | 0.0000031 | 101989734 | Tspan14 | protein_coding | 101989734 | Tspan14 | ENSMUSG00000037824 | Tspan14 | ortholog_one2one | 99.6296 | ENSG00000108219 | TSPAN14 | ortholog_one2one | 97.0370 | NA | NA | NA | NA | NA | NA | 52588 | 52588 | 81619 | 81619 |
| ENSMOCG00000018654 | 235.967362 | -0.3472035 | 0.0783715 | 0.0000001 | 0.0000032 | 101990954 | Slc27a3 | protein_coding | 101990954 | Slc27a3 | ENSMUSG00000027932 | Slc27a3 | ortholog_one2one | 88.7725 | ENSG00000143554 | SLC27A3 | ortholog_one2one | 85.1796 | NA | NA | NA | NA | NA | NA | 26568 | 26568 | 11000 | 11000 |
| ENSMOCG00000020965 | 1000.832400 | 0.2816013 | 0.0606544 | 0.0000001 | 0.0000036 | 101988650 | Lingo3 | protein_coding | 101988650 | Lingo3 | ENSMUSG00000051067 | Lingo3 | ortholog_one2one | 96.4407 | ENSG00000220008 | LINGO3 | ortholog_one2one | 88.6441 | NA | NA | NA | NA | NA | NA | 237403 | 237403 | 645191 | 645191 |
| ENSMOCG00000018609 | 88.738314 | -0.4064587 | 0.0959570 | 0.0000001 | 0.0000037 | 102001627 | Bag3 | protein_coding | 102001627 | Bag3 | ENSMUSG00000030847 | Bag3 | ortholog_one2one | 91.4783 | ENSG00000151929 | BAG3 | ortholog_one2one | 85.9130 | NA | NA | NA | NA | NA | NA | 29810 | 29810 | 9531 | 9531 |
| ENSMOCG00000009504 | 71.431714 | -0.4473357 | 0.1068489 | 0.0000001 | 0.0000037 | 101996726 | Col1a2 | protein_coding | 101996726 | Col1a2 | ENSMUSG00000029661 | Col1a2 | ortholog_one2one | 91.7343 | ENSG00000164692 | COL1A2 | ortholog_one2one | 89.2251 | NA | NA | NA | NA | NA | NA | 12843 | 12843 | 1278 | 1278 |
| ENSMOCG00000010560 | 184.005386 | -0.2917556 | 0.0635258 | 0.0000001 | 0.0000038 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000008782 | 1639.867823 | -0.3939618 | 0.0927440 | 0.0000001 | 0.0000039 | 101996060 | Mag | protein_coding | 101996060 | Mag | ENSMUSG00000036634 | Mag | ortholog_one2one | 96.9649 | ENSG00000105695 | MAG | ortholog_one2one | 93.9297 | NA | NA | NA | NA | NA | NA | 17136 | 17136 | 4099 | 4099 |
| ENSMOCG00000022425 | 1375.526769 | -0.3391978 | 0.0770015 | 0.0000002 | 0.0000040 | 101980882 | Ndn | protein_coding | 101980882 | Ndn | ENSMUSG00000033585 | Ndn | ortholog_one2one | 90.1841 | ENSG00000182636 | NDN | ortholog_one2one | 82.8221 | NA | NA | NA | NA | NA | NA | 17984 | 17984 | 4692 | 4692 |
| ENSMOCG00000002022 | 82.670740 | -0.4789947 | 0.1152541 | 0.0000002 | 0.0000040 | NA | protein_coding | NA | ENSMUSG00000054708 | Ankrd24 | ortholog_one2one | 95.7143 | ENSG00000089847 | ANKRD24 | ortholog_one2one | 84.2857 | NA | NA | NA | NA | NA | NA | 70615 | 70615 | 170961 | 170961 | ||
| ENSMOCG00000002558 | 277.222096 | 0.2529518 | 0.0539117 | 0.0000002 | 0.0000041 | 101997166 | Camk1d | protein_coding | 101997166 | Camk1d | ENSMUSG00000039145 | Camk1d | ortholog_one2one | 99.4805 | ENSG00000183049 | CAMK1D | ortholog_one2one | 97.9221 | NA | NA | NA | NA | NA | NA | 227541 | 227541 | 57118 | 57118 |
| ENSMOCG00000004144 | 654.605294 | -0.3537708 | 0.0813592 | 0.0000002 | 0.0000041 | 101999292 | Gpr37 | protein_coding | 101999292 | Gpr37 | ENSMUSG00000039904 | Gpr37 | ortholog_one2one | 90.2640 | ENSG00000170775 | GPR37 | ortholog_one2one | 82.6733 | NA | NA | NA | NA | NA | NA | 14763 | 14763 | 2861 | 2861 |
| ENSMOCG00000013274 | 263.561081 | 0.6757760 | 0.1551987 | 0.0000002 | 0.0000041 | 101990228 | Rnase4 | protein_coding | 101990228 | Rnase4 | ENSMUSG00000021876 | Rnase4 | ortholog_one2one | 85.8108 | ENSG00000258818 | RNASE4 | ortholog_one2one | 84.4595 | NA | NA | NA | NA | NA | NA | 58809 | 58809 | 6038 | 6038 |
| ENSMOCG00000013158 | 291.576887 | -0.2800125 | 0.0607783 | 0.0000002 | 0.0000042 | 101994413 | Pofut2 | protein_coding | 101994413 | Pofut2 | ENSMUSG00000020260 | Pofut2 | ortholog_one2one | 98.6014 | ENSG00000186866 | POFUT2 | ortholog_one2one | 91.8415 | NA | NA | NA | NA | NA | NA | 80294 | 80294 | 23275 | 23275 |
| ENSMOCG00000012006 | 104.072509 | -0.9246759 | 0.2134189 | 0.0000002 | 0.0000042 | 102002132 | Sertm1 | protein_coding | 102002132 | Sertm1 | ENSMUSG00000056306 | Sertm1 | ortholog_one2one | 96.2617 | ENSG00000180440 | SERTM1 | ortholog_one2one | 95.3271 | NA | NA | NA | NA | NA | NA | 329641 | 329641 | 400120 | 400120 |
| ENSMOCG00000018119 | 617.909567 | 0.2881944 | 0.0629992 | 0.0000002 | 0.0000042 | 101979528 | protein_coding | 101979528 | ENSMUSG00000030465 | Psd3 | ortholog_one2many | 89.3617 | ENSG00000156011 | PSD3 | ortholog_one2many | 87.7660 | NA | NA | NA | NA | NA | NA | 234353 | 234353 | 23362 | 23362 | ||
| ENSMOCG00000004156 | 102.430423 | 0.3936337 | 0.0932648 | 0.0000002 | 0.0000043 | 101982186 | Mks1 | protein_coding | 101982186 | Mks1 | ENSMUSG00000034121 | Mks1 | ortholog_one2one | 94.1176 | ENSG00000011143 | MKS1 | ortholog_one2one | 88.4135 | NA | NA | NA | NA | NA | NA | 380718 | 380718 | 54903 | 54903 |
| ENSMOCG00000021194 | 62.824828 | -0.5232899 | 0.1259348 | 0.0000002 | 0.0000044 | 101990610 | Cdc42ep2 | protein_coding | 101990610 | Cdc42ep2 | ENSMUSG00000045664 | Cdc42ep2 | ortholog_one2one | 94.8598 | ENSG00000149798 | CDC42EP2 | ortholog_one2one | 86.9159 | NA | NA | NA | NA | NA | NA | 104252 | 104252 | 10435 | 10435 |
| ENSMOCG00000018548 | 57.607456 | -0.5915489 | 0.1398299 | 0.0000002 | 0.0000044 | 101996979 | Aldh1a1 | protein_coding | 101996979 | Aldh1a1 | ENSMUSG00000053279 | Aldh1a1 | ortholog_one2one | 94.6108 | ENSG00000165092 | ALDH1A1 | ortholog_one2many | 85.8283 | NA | NA | NA | NA | NA | NA | 11668, 320092 | 11668 | 216 | 216 |
| ENSMOCG00000015901 | 3103.345638 | 0.2695604 | 0.0582961 | 0.0000002 | 0.0000044 | 101997393 | Inf2 | protein_coding | 101997393 | Inf2 | ENSMUSG00000037679 | Inf2 | ortholog_one2one | 90.0319 | ENSG00000203485 | INF2 | ortholog_one2one | 78.8676 | NA | NA | NA | NA | NA | NA | 70435 | 70435 | 64423 | 64423 |
| ENSMOCG00000008428 | 47.699493 | -0.9191970 | 0.2127913 | 0.0000002 | 0.0000044 | 101984563 | Htr7 | protein_coding | 101984563 | Htr7 | ENSMUSG00000024798 | Htr7 | ortholog_one2one | 95.7447 | ENSG00000148680 | HTR7 | ortholog_one2one | 88.5106 | NA | NA | NA | NA | NA | NA | 15566 | 15566 | 3363 | 3363 |
| ENSMOCG00000021969 | 209.793832 | 0.3424818 | 0.0786052 | 0.0000002 | 0.0000045 | 101986559 | protein_coding | 101986559 | ENSMUSG00000020268 | Lyrm7 | ortholog_one2many | 88.4615 | ENSG00000186687 | LYRM7 | ortholog_one2many | 84.6154 | NA | NA | NA | NA | NA | NA | 75530 | 75530 | 90624 | 90624 | ||
| ENSMOCG00000019373 | 113.263667 | -0.5895236 | 0.1399763 | 0.0000002 | 0.0000046 | 101986405 | protein_coding | 101986405 | ENSMUSG00000038587 | Akap12 | ortholog_one2one | 82.5123 | ENSG00000131016 | AKAP12 | ortholog_one2one | 71.9212 | NA | NA | NA | NA | NA | NA | 83397 | 83397 | 9590 | 9590 | ||
| ENSMOCG00000013076 | 178.508146 | -0.3855885 | 0.0914486 | 0.0000002 | 0.0000047 | 101994542 | Snx33 | protein_coding | 101994542 | Snx33 | ENSMUSG00000032733 | Snx33 | ortholog_one2one | 91.6376 | ENSG00000173548 | SNX33 | ortholog_one2one | 90.7665 | NA | NA | NA | NA | NA | NA | 235406 | 235406 | 257364 | 257364 |
| ENSMOCG00000019577 | 46.013740 | -0.5423591 | 0.1308772 | 0.0000002 | 0.0000048 | 101995523 | Flywch2 | protein_coding | 101995523 | Flywch2 | ENSMUSG00000023911 | Flywch2 | ortholog_one2one | 77.6978 | ENSG00000162076 | FLYWCH2 | ortholog_one2one | 71.2230 | NA | NA | NA | NA | NA | NA | 76917 | 76917 | 114984 | 114984 |
| ENSMOCG00000004124 | 96.941543 | -0.3698595 | 0.0870535 | 0.0000002 | 0.0000049 | 101994683 | Isl1 | protein_coding | 101994683 | Isl1 | ENSMUSG00000042258 | Isl1 | ortholog_one2one | 99.7135 | ENSG00000016082 | ISL1 | ortholog_one2one | 99.7135 | NA | NA | NA | NA | NA | NA | 16392 | 16392 | 3670 | 3670 |
| ENSMOCG00000005220 | 221.800401 | -0.3245905 | 0.0737624 | 0.0000002 | 0.0000049 | 101985027 | Lrfn1 | protein_coding | 101985027 | Lrfn1 | ENSMUSG00000030600 | Lrfn1 | ortholog_one2one | 98.1651 | ENSG00000128011 | LRFN1 | ortholog_one2one | 95.2818 | NA | NA | NA | NA | NA | NA | 80749 | 80749 | 57622 | 57622 |
| ENSMOCG00000017792 | 60.200578 | 1.1320121 | 0.2834124 | 0.0000002 | 0.0000049 | 101979560 | Tmc8 | protein_coding | 101979560 | Tmc8 | ENSMUSG00000050106 | Tmc8 | ortholog_one2one | 89.3354 | ENSG00000167895 | TMC8 | ortholog_one2one | 75.8887 | NA | NA | NA | NA | NA | NA | 217356 | 217356 | 147138 | 147138 |
| ENSMOCG00000020887 | 35.734020 | 0.6580646 | 0.1539931 | 0.0000002 | 0.0000050 | 101980489 | Trhr | protein_coding | 101980489 | Trhr | ENSMUSG00000038760 | Trhr | ortholog_one2one | 93.4673 | ENSG00000174417 | TRHR | ortholog_one2one | 94.4724 | NA | NA | NA | NA | NA | NA | 22045 | 22045 | 7201 | 7201 |
| ENSMOCG00000014320 | 66.105980 | 0.6046801 | 0.1436956 | 0.0000002 | 0.0000050 | 101998941 | Hcrtr2 | protein_coding | 101998941 | Hcrtr2 | ENSMUSG00000032360 | Hcrtr2 | ortholog_one2one | 98.2609 | ENSG00000137252 | HCRTR2 | ortholog_one2one | 91.5217 | NA | NA | NA | NA | NA | NA | 387285 | 387285 | 3062 | 3062 |
| ENSMOCG00000012439 | 118.714642 | -0.4028996 | 0.0968349 | 0.0000002 | 0.0000050 | 101994020 | Gpc4 | protein_coding | 101994020 | Gpc4 | ENSMUSG00000031119 | Gpc4 | ortholog_one2one | 94.9640 | ENSG00000076716 | GPC4 | ortholog_one2one | 92.0863 | NA | NA | NA | NA | NA | NA | 14735 | 14735 | 2239 | 2239 |
| ENSMOCG00000015093 | 56.093331 | -0.8924379 | 0.2073392 | 0.0000002 | 0.0000050 | 101991198 | Steap2 | protein_coding | 101991198 | Steap2 | ENSMUSG00000015653 | Steap2 | ortholog_one2one | 97.9550 | ENSG00000157214 | STEAP2 | ortholog_one2one | 96.3190 | NA | NA | NA | NA | NA | NA | 74051 | 74051 | 261729 | 261729 |
| ENSMOCG00000010433 | 81.553227 | 0.4439795 | 0.1082451 | 0.0000002 | 0.0000050 | 101979999 | protein_coding | 101979999 | ENSMUSG00000022881 | Rfc4 | ortholog_one2many | 85.4396 | ENSG00000163918 | RFC4 | ortholog_one2many | 87.0879 | NA | NA | NA | NA | NA | NA | 106344 | 106344 | 5984 | 5984 | ||
| ENSMOCG00000019925 | 116.778992 | -0.4423972 | 0.1079723 | 0.0000002 | 0.0000052 | 101983097 | P2rx7 | protein_coding | 101983097 | P2rx7 | ENSMUSG00000029468 | P2rx7 | ortholog_one2one | 86.0507 | ENSG00000089041 | P2RX7 | ortholog_one2one | 80.6159 | NA | NA | NA | NA | NA | NA | 18439 | 18439 | 5027 | 5027 |
| ENSMOCG00000011384 | 45.474071 | -0.9847459 | 0.2356241 | 0.0000002 | 0.0000054 | 101989417 | Klhl1 | protein_coding | 101989417 | Klhl1 | ENSMUSG00000022076 | Klhl1 | ortholog_one2one | 97.7303 | ENSG00000150361 | KLHL1 | ortholog_one2one | 94.5260 | NA | NA | NA | NA | NA | NA | 93688 | 93688 | 57626 | 57626 |
| ENSMOCG00000018447 | 87.471532 | -0.4678975 | 0.1148711 | 0.0000002 | 0.0000054 | 101988308 | protein_coding | 101988308 | ENSMUSG00000035772 | Mrps2 | ortholog_one2many | 89.3103 | ENSG00000122140 | MRPS2 | ortholog_one2many | 70.3448 | NA | NA | NA | NA | NA | NA | 118451 | 118451 | 51116 | 51116 | ||
| ENSMOCG00000003806 | 13.178032 | -1.3714152 | 0.3711967 | 0.0000002 | 0.0000054 | NA | Saa4 | protein_coding | NA | Saa4 | ENSMUSG00000040017 | Saa4 | ortholog_one2one | 83.7209 | ENSG00000148965 | SAA4 | ortholog_one2one | 57.3643 | NA | NA | NA | NA | NA | NA | 20211 | 20211 | 6291 | 6291 |
| ENSMOCG00000013374 | 930.209309 | -0.2612380 | 0.0568577 | 0.0000002 | 0.0000054 | 101980228 | Ache | protein_coding | 101980228 | Ache | ENSMUSG00000023328 | Ache | ortholog_one2one | 96.5798 | ENSG00000087085 | ACHE | ortholog_one2one | 89.0880 | NA | NA | NA | NA | NA | NA | 11423 | 11423 | 43 | 43 |
| ENSMOCG00000006136 | 131.622236 | -0.3330657 | 0.0767543 | 0.0000002 | 0.0000055 | 101995788 | Spats2l | protein_coding | 101995788 | Spats2l | ENSMUSG00000038305 | Spats2l | ortholog_one2one | 90.7965 | ENSG00000196141 | SPATS2L | ortholog_one2one | 87.4336 | NA | NA | NA | NA | NA | NA | 67198 | 67198 | 26010 | 26010 |
| ENSMOCG00000002116 | 125.968857 | 0.3150659 | 0.0716406 | 0.0000002 | 0.0000056 | 101992504 | Chsy3 | protein_coding | 101992504 | Chsy3 | ENSMUSG00000058152 | Chsy3 | ortholog_one2one | 94.1176 | ENSG00000198108 | CHSY3 | ortholog_one2one | 91.9683 | NA | NA | NA | NA | NA | NA | 78923 | 78923 | 337876 | 337876 |
| ENSMOCG00000011552 | 45.118093 | -1.8339964 | 0.5276487 | 0.0000002 | 0.0000057 | 101987761 | Ngfr | protein_coding | 101987761 | Ngfr | ENSMUSG00000000120 | Ngfr | ortholog_one2one | 93.4579 | ENSG00000064300 | NGFR | ortholog_one2one | 91.8224 | NA | NA | NA | NA | NA | NA | 18053 | 18053 | 4804 | 4804 |
| ENSMOCG00000005062 | 8.556598 | -4.3871097 | 1.0926159 | 0.0000002 | 0.0000057 | 101985106 | protein_coding | 101985106 | ENSMUSG00000027076 | Timm10 | ortholog_one2many | 100.0000 | ENSG00000134809 | TIMM10 | ortholog_one2many | 100.0000 | NA | NA | NA | NA | NA | NA | 30059 | 30059 | 26519 | 26519 | ||
| ENSMOCG00000011513 | 531.010737 | -0.3108330 | 0.0705051 | 0.0000002 | 0.0000057 | 101981684 | Npy | protein_coding | 101981684 | Npy | ENSMUSG00000029819 | Npy | ortholog_one2one | 95.8763 | ENSG00000122585 | NPY | ortholog_one2one | 93.8144 | NA | NA | NA | NA | NA | NA | 109648 | 109648 | 4852 | 4852 |
| ENSMOCG00000007627 | 109.694462 | 0.3318892 | 0.0767288 | 0.0000002 | 0.0000058 | 101994055 | Ddx19b | protein_coding | 101994055 | Ddx19b | ENSMUSG00000033658 | Ddx19b | ortholog_one2one | 88.7202 | ENSG00000157349 | DDX19B | ortholog_one2one | 91.1063 | NA | NA | NA | NA | NA | NA | 234733 | 234733 | 11269 | 11269 |
| ENSMOCG00000021747 | 405.212626 | -0.3495849 | 0.0821253 | 0.0000002 | 0.0000060 | 102001082 | Sox10 | protein_coding | 102001082 | Sox10 | ENSMUSG00000033006 | Sox10 | ortholog_one2one | 99.5708 | ENSG00000100146 | SOX10 | ortholog_one2one | 98.0687 | NA | NA | NA | NA | NA | NA | 20665 | 20665 | 6663 | 6663 |
| ENSMOCG00000018005 | 87.149924 | -0.3848307 | 0.0927512 | 0.0000003 | 0.0000060 | 101989915 | Selenoh | protein_coding | 101989915 | Selenoh | ENSMUSG00000076437 | Selenoh | ortholog_one2one | 92.5000 | ENSG00000211450 | SELENOH | ortholog_one2one | 71.6667 | NA | NA | NA | NA | NA | NA | 72657 | 72657 | 280636 | 280636 |
| ENSMOCG00000011833 | 83.485005 | -0.5044084 | 0.1246136 | 0.0000003 | 0.0000061 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000002257 | 590.139391 | 0.2579710 | 0.0564465 | 0.0000003 | 0.0000061 | 101998534 | Abl2 | protein_coding | 101998534 | Abl2 | ENSMUSG00000026596 | Abl2 | ortholog_one2one | 97.9678 | ENSG00000143322 | ABL2 | ortholog_one2one | 95.4276 | NA | NA | NA | NA | NA | NA | 11352 | 11352 | 27 | 27 |
| ENSMOCG00000001886 | 96.846694 | -0.4544651 | 0.1125661 | 0.0000003 | 0.0000062 | 101980725 | Sh3tc2 | protein_coding | 101980725 | Sh3tc2 | ENSMUSG00000045629 | Sh3tc2 | ortholog_one2one | 90.4503 | ENSG00000169247 | SH3TC2 | ortholog_one2one | 83.1522 | NA | NA | NA | NA | NA | NA | 225608 | 225608 | 79628 | 79628 |
| ENSMOCG00000022625 | 250.153447 | -0.4612672 | 0.1143543 | 0.0000003 | 0.0000062 | 102000114 | Ermn | protein_coding | 102000114 | Ermn | ENSMUSG00000026830 | Ermn | ortholog_one2one | 74.7331 | ENSG00000136541 | ERMN | ortholog_one2one | 64.7687 | NA | NA | NA | NA | NA | NA | 77767 | 77767 | 57471 | 57471 |
| ENSMOCG00000021065 | 228.552673 | -0.3453488 | 0.0811546 | 0.0000003 | 0.0000062 | 101992512 | Foxp4 | protein_coding | 101992512 | Foxp4 | ENSMUSG00000023991 | Foxp4 | ortholog_one2one | 96.8750 | ENSG00000137166 | FOXP4 | ortholog_one2one | 93.3036 | NA | NA | NA | NA | NA | NA | 74123 | 74123 | 116113 | 116113 |
| ENSMOCG00000014447 | 264.443501 | -0.2826906 | 0.0631255 | 0.0000003 | 0.0000064 | 102001185 | Ptpdc1 | protein_coding | 102001185 | Ptpdc1 | ENSMUSG00000038042 | Ptpdc1 | ortholog_one2one | 89.3758 | ENSG00000158079 | PTPDC1 | ortholog_one2one | 79.9469 | NA | NA | NA | NA | NA | NA | 218232 | 218232 | 138639 | 138639 |
| ENSMOCG00000008511 | 22.478626 | -1.1035752 | 0.2802642 | 0.0000003 | 0.0000064 | 102002534 | Adra1b | protein_coding | 102002534 | Adra1b | ENSMUSG00000050541 | Adra1b | ortholog_one2one | 98.2524 | ENSG00000170214 | ADRA1B | ortholog_one2one | 96.1165 | NA | NA | NA | NA | NA | NA | 11548 | 11548 | 147 | 147 |
| ENSMOCG00000017508 | 84.423187 | -0.7039542 | 0.1666991 | 0.0000003 | 0.0000066 | 101980042 | Foxj1 | protein_coding | 101980042 | Foxj1 | ENSMUSG00000034227 | Foxj1 | ortholog_one2one | 97.3872 | ENSG00000129654 | FOXJ1 | ortholog_one2one | 94.2993 | NA | NA | NA | NA | NA | NA | 15223 | 15223 | 2302 | 2302 |
| ENSMOCG00000022081 | 150.020383 | -0.5951083 | 0.1448328 | 0.0000003 | 0.0000066 | 101998727 | Trpc4 | protein_coding | 101998727 | Trpc4 | ENSMUSG00000027748 | Trpc4 | ortholog_one2one | 97.8417 | ENSG00000133107 | TRPC4 | ortholog_one2one | 96.5057 | NA | NA | NA | NA | NA | NA | 22066 | 22066 | 7223 | 7223 |
| ENSMOCG00000003355 | 103.951662 | -0.3559325 | 0.0847022 | 0.0000003 | 0.0000067 | 102001368 | Pcsk6 | protein_coding | 102001368 | Pcsk6 | ENSMUSG00000030513 | Pcsk6 | ortholog_one2one | 97.0046 | ENSG00000140479 | PCSK6 | ortholog_one2one | 93.0876 | NA | NA | NA | NA | NA | NA | 18553 | 18553 | 5046 | 5046 |
| ENSMOCG00000009076 | 30.104105 | -0.6255138 | 0.1511745 | 0.0000003 | 0.0000068 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000016874 | 76.617618 | -0.4759107 | 0.1187670 | 0.0000003 | 0.0000068 | 101999172 | Abtb3 | protein_coding | 101999172 | Abtb3 | ENSMUSG00000020042 | Abtb3 | ortholog_one2one | 98.1149 | ENSG00000151136 | ABTB3 | ortholog_one2one | 96.4991 | NA | NA | NA | NA | NA | NA | 74007 | 74007 | 121551 | 121551 |
| ENSMOCG00000009988 | 3586.104711 | 0.2883463 | 0.0649107 | 0.0000003 | 0.0000068 | 101996589 | Rgs9 | protein_coding | 101996589 | Rgs9 | ENSMUSG00000020599 | Rgs9 | ortholog_one2one | 96.0118 | ENSG00000108370 | RGS9 | ortholog_one2one | 89.9557 | NA | NA | NA | NA | NA | NA | 19739 | 19739 | 8787 | 8787 |
| ENSMOCG00000003711 | 826.726077 | 0.2761839 | 0.0616955 | 0.0000003 | 0.0000070 | 101986039 | Dcbld2 | protein_coding | 101986039 | Dcbld2 | ENSMUSG00000035107 | Dcbld2 | ortholog_one2one | 88.6744 | ENSG00000057019 | DCBLD2 | ortholog_one2one | 84.9421 | NA | NA | NA | NA | NA | NA | 73379 | 73379 | 131566 | 131566 |
| ENSMOCG00000019214 | 174.756686 | -0.5478954 | 0.1357687 | 0.0000003 | 0.0000071 | 101981120 | Pygl | protein_coding | 101981120 | Pygl | ENSMUSG00000021069 | Pygl | ortholog_one2one | 97.4057 | ENSG00000100504 | PYGL | ortholog_one2one | 93.7500 | NA | NA | NA | NA | NA | NA | 110095 | 110095 | 5836 | 5836 |
| ENSMOCG00000016356 | 28.466060 | 0.6411509 | 0.1550359 | 0.0000003 | 0.0000073 | 101988475 | Fancd2os | protein_coding | 101988475 | Fancd2os | ENSMUSG00000033963 | Fancd2os | ortholog_one2one | 94.9438 | ENSG00000163705 | FANCD2OS | ortholog_one2one | 91.5730 | NA | NA | NA | NA | NA | NA | 70979 | 70979 | 115795 | 115795 |
| ENSMOCG00000010483 | 262.664690 | 0.4546918 | 0.1138340 | 0.0000003 | 0.0000073 | 101987227 | Syt10 | protein_coding | 101987227 | Syt10 | ENSMUSG00000063260 | Syt10 | ortholog_one2one | 92.0904 | ENSG00000110975 | SYT10 | ortholog_one2one | 88.3239 | NA | NA | NA | NA | NA | NA | 54526 | 54526 | 341359 | 341359 |
| ENSMOCG00000007280 | 346.765284 | 0.3147738 | 0.0727892 | 0.0000003 | 0.0000074 | NA | Lrp1b | protein_coding | NA | Lrp1b | ENSMUSG00000049252 | Lrp1b | ortholog_one2one | 94.5785 | ENSG00000168702 | LRP1B | ortholog_one2one | 92.2848 | NA | NA | NA | NA | NA | NA | 94217 | 94217 | 53353 | 53353 |
| ENSMOCG00000008887 | 88.787553 | -0.3646657 | 0.0879569 | 0.0000003 | 0.0000074 | 101999127 | Faap20 | protein_coding | 101999127 | Faap20 | ENSMUSG00000073684 | Faap20 | ortholog_one2one | 77.4194 | ENSG00000162585 | FAAP20 | ortholog_one2one | 54.3011 | NA | NA | NA | NA | NA | NA | 67513 | 67513 | 199990 | 199990 |
| ENSMOCG00000016980 | 83.628024 | -0.3882192 | 0.0953049 | 0.0000003 | 0.0000076 | 101981744 | Dnph1 | protein_coding | 101981744 | Dnph1 | ENSMUSG00000040658 | Dnph1 | ortholog_one2one | 81.0976 | ENSG00000112667 | DNPH1 | ortholog_one2one | 76.2195 | NA | NA | NA | NA | NA | NA | 381101 | 381101 | 10591 | 10591 |
| ENSMOCG00000003980 | 20.272382 | -0.9550688 | 0.2342164 | 0.0000003 | 0.0000079 | 102000249 | Asah2 | protein_coding | 102000249 | Asah2 | ENSMUSG00000024887 | Asah2 | ortholog_one2one | 88.7566 | ENSG00000188611 | ASAH2 | ortholog_one2many | 81.7460 | ENSMUSG00000024887, ENSMUSG00000024887 | Asah2, Asah2 | 88.7566, 88.7566 | ENSG00000188611, ENSG00000204147 | ASAH2, ASAH2B | 81.746, 16.4021 | 54447 | 54447 | 56624 | 56624 |
| ENSMOCG00000004315 | 598.124712 | 0.2561310 | 0.0569360 | 0.0000004 | 0.0000081 | 102002798 | Caln1 | protein_coding | 102002798 | Caln1 | ENSMUSG00000060371 | Caln1 | ortholog_one2one | 98.8506 | ENSG00000183166 | CALN1 | ortholog_one2one | 95.7854 | NA | NA | NA | NA | NA | NA | 140904 | 140904 | 83698 | 83698 |
| ENSMOCG00000010420 | 200.546539 | -0.2565467 | 0.0570918 | 0.0000004 | 0.0000082 | 101982419 | Ufsp2 | protein_coding | 101982419 | Ufsp2 | ENSMUSG00000031634 | Ufsp2 | ortholog_one2one | 86.9379 | ENSG00000109775 | UFSP2 | ortholog_one2one | 82.8694 | NA | NA | NA | NA | NA | NA | 192169 | 192169 | 55325 | 55325 |
| ENSMOCG00000006049 | 1549.401457 | 0.2641326 | 0.0591020 | 0.0000004 | 0.0000083 | 101996419 | Sacs | protein_coding | 101996419 | Sacs | ENSMUSG00000048279 | Sacs | ortholog_one2one | 97.0543 | ENSG00000151835 | SACS | ortholog_one2one | 93.6504 | NA | NA | NA | NA | NA | NA | 50720 | 50720 | 26278 | 26278 |
| ENSMOCG00000012997 | 421.432208 | 0.2501654 | 0.0556067 | 0.0000004 | 0.0000086 | 101986976 | Cyp7b1 | protein_coding | 101986976 | Cyp7b1 | ENSMUSG00000039519 | Cyp7b1 | ortholog_one2one | 72.7811 | ENSG00000172817 | CYP7B1 | ortholog_one2one | 65.8777 | NA | NA | NA | NA | NA | NA | 13123 | 13123 | 9420 | 9420 |
| ENSMOCG00000014619 | 226.715544 | -0.2830520 | 0.0643484 | 0.0000004 | 0.0000086 | 101981687 | Iglon5 | protein_coding | 101981687 | Iglon5 | ENSMUSG00000013367 | Iglon5 | ortholog_one2one | 94.6108 | ENSG00000142549 | IGLON5 | ortholog_one2one | 93.1138 | NA | NA | NA | NA | NA | NA | 210094 | 210094 | 402665 | 402665 |
| ENSMOCG00000014791 | 145.722592 | -0.3086669 | 0.0719194 | 0.0000004 | 0.0000091 | 101986904 | Psmg3 | protein_coding | 101986904 | Psmg3 | ENSMUSG00000029551 | Psmg3 | ortholog_one2one | 94.2623 | ENSG00000157778 | PSMG3 | ortholog_one2one | 90.1639 | NA | NA | NA | NA | NA | NA | 66506 | 66506 | 84262 | 84262 |
| ENSMOCG00000008480 | 196.566667 | -0.2719138 | 0.0615016 | 0.0000004 | 0.0000091 | 101997806 | Ubash3b | protein_coding | 101997806 | Ubash3b | ENSMUSG00000032020 | Ubash3b | ortholog_one2one | 99.0596 | ENSG00000154127 | UBASH3B | ortholog_one2one | 97.9624 | NA | NA | NA | NA | NA | NA | 72828 | 72828 | 84959 | 84959 |
| ENSMOCG00000015645 | 172.314751 | -0.3963595 | 0.0989610 | 0.0000004 | 0.0000092 | 101983622 | Ano4 | protein_coding | 101983622 | Ano4 | ENSMUSG00000035189 | Ano4 | ortholog_one2one | 98.7435 | ENSG00000151572 | ANO4 | ortholog_one2one | 97.6963 | NA | NA | NA | NA | NA | NA | 320091 | 320091 | 121601 | 121601 |
| ENSMOCG00000007447 | 220.395887 | -0.2746725 | 0.0624590 | 0.0000004 | 0.0000096 | 101981822 | protein_coding | 101981822 | ENSMUSG00000038812 | Trmt112 | ortholog_one2many | 96.8000 | ENSG00000173113 | TRMT112 | ortholog_one2many | 72.0000 | NA | NA | NA | NA | NA | NA | 67674 | 67674 | 51504 | 51504 | ||
| ENSMOCG00000015029 | 126.253849 | -0.3671143 | 0.0902918 | 0.0000004 | 0.0000096 | 101980030 | Rgs11 | protein_coding | 101980030 | Rgs11 | ENSMUSG00000024186 | Rgs11 | ortholog_one2one | 89.5075 | ENSG00000076344 | RGS11 | ortholog_one2one | 77.5161 | NA | NA | NA | NA | NA | NA | 50782 | 50782 | 8786 | 8786 |
| ENSMOCG00000014394 | 436.114405 | -0.3434999 | 0.0828988 | 0.0000004 | 0.0000096 | 101985439 | Folh1 | protein_coding | 101985439 | Folh1 | ENSMUSG00000001773 | Folh1 | ortholog_one2one | 86.8742 | ENSG00000086205 | FOLH1 | ortholog_one2one | 83.7618 | NA | NA | NA | NA | NA | NA | 53320 | 53320 | 2346 | 2346 |
| ENSMOCG00000009624 | 168.418432 | -0.2550735 | 0.0573025 | 0.0000004 | 0.0000097 | 101994010, 101998895 | Cetn3, Cetn3 | protein_coding | 101994010 | Cetn3 | ENSMUSG00000021537 | Cetn3 | ortholog_one2one | 97.0060 | ENSG00000153140 | CETN3 | ortholog_one2one | 97.6048 | NA | NA | NA | NA | NA | NA | 12626 | 12626 | 1070 | 1070 |
| ENSMOCG00000002279 | 1643.535736 | -0.2649801 | 0.0599157 | 0.0000005 | 0.0000097 | 102001823 | Nrxn2 | protein_coding | 102001823 | Nrxn2 | ENSMUSG00000033768 | Nrxn2 | ortholog_one2one | 98.6534 | ENSG00000110076 | NRXN2 | ortholog_one2one | 97.9508 | NA | NA | NA | NA | NA | NA | 18190 | 18190 | 9379 | 9379 |
| ENSMOCG00000013540 | 946.507393 | -0.4678404 | 0.1198495 | 0.0000005 | 0.0000099 | 101992393 | Nrip3 | protein_coding | 101992393 | Nrip3 | ENSMUSG00000034825 | Nrip3 | ortholog_one2one | 95.6175 | ENSG00000175352 | NRIP3 | ortholog_one2one | 88.0478 | NA | NA | NA | NA | NA | NA | 78593 | 78593 | 56675 | 56675 |
| ENSMOCG00000010808 | 94.917958 | 0.3089077 | 0.0725067 | 0.0000005 | 0.0000100 | NA | Rnf170 | protein_coding | NA | Rnf170 | ENSMUSG00000013878 | Rnf170 | ortholog_one2one | 82.7839 | ENSG00000120925 | RNF170 | ortholog_one2one | 74.3590 | NA | NA | NA | NA | NA | NA | 77733 | 77733 | 81790 | 81790 |
| ENSMOCG00000016220 | 51.183923 | -0.5648881 | 0.1432377 | 0.0000005 | 0.0000103 | 101986956 | Ankrd55 | protein_coding | 101986956 | Ankrd55 | ENSMUSG00000049985 | Ankrd55 | ortholog_one2one | 89.5595 | ENSG00000164512 | ANKRD55 | ortholog_one2one | 85.3181 | NA | NA | NA | NA | NA | NA | 77318 | 77318 | 79722 | 79722 |
| ENSMOCG00000022606 | 135.957048 | 0.3061477 | 0.0720480 | 0.0000005 | 0.0000109 | 101987618 | Zbtb33 | protein_coding | 101987618 | Zbtb33 | ENSMUSG00000048047 | Zbtb33 | ortholog_one2one | 90.3077 | ENSG00000177485 | ZBTB33 | ortholog_one2one | 89.0769 | NA | NA | NA | NA | NA | NA | 56805 | 56805 | 10009 | 10009 |
| ENSMOCG00000006035 | 60.822337 | -0.3973126 | 0.1006844 | 0.0000005 | 0.0000112 | 101982872 | Sync | protein_coding | 101982872 | Sync | ENSMUSG00000001333 | Sync | ortholog_one2one | 84.3424 | ENSG00000162520 | SYNC | ortholog_one2one | 76.6180 | NA | NA | NA | NA | NA | NA | 68828 | 68828 | 81493 | 81493 |
| ENSMOCG00000002589 | 37.795903 | -0.9781889 | 0.2498518 | 0.0000005 | 0.0000114 | 102002888 | Tsnaxip1 | protein_coding | 102002888 | Tsnaxip1 | ENSMUSG00000031893 | Tsnaxip1 | ortholog_one2one | 82.6025 | ENSG00000102904 | TSNAXIP1 | ortholog_one2one | 76.2376 | NA | NA | NA | NA | NA | NA | 72236 | 72236 | 55815 | 55815 |
| ENSMOCG00000017576 | 47.931382 | -0.5799943 | 0.1477918 | 0.0000005 | 0.0000116 | 101999262 | Epb41l4a | protein_coding | 101999262 | Epb41l4a | ENSMUSG00000024376 | Epb41l4a | ortholog_one2one | 96.2099 | ENSG00000129595 | EPB41L4A | ortholog_one2one | 93.8775 | NA | NA | NA | NA | NA | NA | 13824 | 13824 | 64097 | 64097 |
| ENSMOCG00000017575 | 248.539356 | -0.2611369 | 0.0595122 | 0.0000005 | 0.0000116 | 101982579 | Plekha7 | protein_coding | 101982579 | Plekha7 | ENSMUSG00000045659 | Plekha7 | ortholog_one2one | 94.9316 | ENSG00000166689 | PLEKHA7 | ortholog_one2one | 89.7023 | NA | NA | NA | NA | NA | NA | 233765 | 233765 | 144100 | 144100 |
| ENSMOCG00000011265 | 63.291716 | -0.6607851 | 0.1657069 | 0.0000006 | 0.0000123 | 101978950 | Ninj2 | protein_coding | 101978950 | Ninj2 | ENSMUSG00000041377 | Ninj2 | ortholog_one2one | 75.1938 | ENSG00000171840 | NINJ2 | ortholog_one2one | 81.3953 | NA | NA | NA | NA | NA | NA | 29862 | 29862 | 4815 | 4815 |
| ENSMOCG00000019745 | 25.911929 | -0.8663011 | 0.2161352 | 0.0000006 | 0.0000123 | 101986536 | Tmprss5 | protein_coding | 101986536 | Tmprss5 | ENSMUSG00000032268 | Tmprss5 | ortholog_one2one | 84.3882 | ENSG00000166682 | TMPRSS5 | ortholog_one2one | 75.5274 | NA | NA | NA | NA | NA | NA | 80893 | 80893 | 80975 | 80975 |
| ENSMOCG00000015647 | 900.049004 | -0.2544112 | 0.0580743 | 0.0000006 | 0.0000128 | 102001907 | Inpp5f | protein_coding | 102001907 | Inpp5f | ENSMUSG00000042105 | Inpp5f | ortholog_one2one | 91.4311 | ENSG00000198825 | INPP5F | ortholog_one2one | 90.4594 | NA | NA | NA | NA | NA | NA | 101490 | 101490 | 22876 | 22876 |
| ENSMOCG00000001279 | 79.080436 | -0.3856753 | 0.0980560 | 0.0000006 | 0.0000130 | 101982612 | Dll1 | protein_coding | 101982612 | Dll1 | ENSMUSG00000014773 | Dll1 | ortholog_one2one | 94.5355 | ENSG00000198719 | DLL1 | ortholog_one2one | 89.0710 | NA | NA | NA | NA | NA | NA | 13388 | 13388 | 28514 | 28514 |
| ENSMOCG00000010258 | 417.646800 | -0.2577274 | 0.0590803 | 0.0000006 | 0.0000132 | 101982087 | Vwa8 | protein_coding | 101982087 | Vwa8 | ENSMUSG00000058997 | Vwa8 | ortholog_one2one | 89.6296 | ENSG00000102763 | VWA8 | ortholog_one2one | 85.4497 | NA | NA | NA | NA | NA | NA | 219189 | 219189 | 23078 | 23078 |
| ENSMOCG00000011108 | 11.410217 | -1.1380338 | 0.3144238 | 0.0000006 | 0.0000133 | 101999452 | Hebp2 | protein_coding | 101999452 | Hebp2 | ENSMUSG00000019853 | Hebp2 | ortholog_one2one | 88.7805 | ENSG00000051620 | HEBP2 | ortholog_one2one | 82.4390 | NA | NA | NA | NA | NA | NA | 56016 | 56016 | 23593 | 23593 |
| ENSMOCG00000001376 | 172.050231 | 0.2748445 | 0.0638712 | 0.0000007 | 0.0000136 | 101984940 | Zfp786 | protein_coding | 101984940 | Zfp786 | ENSMUSG00000051499 | Zfp786 | ortholog_one2one | 77.9085 | ENSG00000197362 | ZNF786 | ortholog_one2one | 63.6601 | NA | NA | NA | NA | NA | NA | 330301 | 330301 | 136051 | 136051 |
| ENSMOCG00000019543 | 123.137032 | -0.2995453 | 0.0711260 | 0.0000007 | 0.0000136 | 101979396 | Fchsd1 | protein_coding | 101979396 | Fchsd1 | ENSMUSG00000038524 | Fchsd1 | ortholog_one2one | 95.6395 | ENSG00000197948 | FCHSD1 | ortholog_one2one | 90.6977 | NA | NA | NA | NA | NA | NA | 319262 | 319262 | 89848 | 89848 |
| ENSMOCG00000004294 | 1312.545490 | -0.3215850 | 0.0779156 | 0.0000007 | 0.0000136 | NA | Bcas1 | protein_coding | NA | Bcas1 | ENSMUSG00000013523 | Bcas1 | ortholog_one2one | 77.4194 | ENSG00000064787 | BCAS1 | ortholog_one2one | 65.1952 | NA | NA | NA | NA | NA | NA | 76960 | 76960 | 8537 | 8537 |
| ENSMOCG00000009571 | 1309.879319 | 0.2648851 | 0.0611996 | 0.0000007 | 0.0000138 | 101994457 | Dpy19l3 | protein_coding | 101994457 | Dpy19l3 | ENSMUSG00000043671 | Dpy19l3 | ortholog_one2one | 95.1117 | ENSG00000178904 | DPY19L3 | ortholog_one2one | 87.4302 | NA | NA | NA | NA | NA | NA | 233115 | 233115 | 147991 | 147991 |
| ENSMOCG00000016717 | 272.444129 | -0.3122710 | 0.0753669 | 0.0000007 | 0.0000146 | 101986509 | Lrrc23 | protein_coding | 101986509 | Lrrc23 | ENSMUSG00000030125 | Lrrc23 | ortholog_one2one | 86.5889 | ENSG00000010626 | LRRC23 | ortholog_one2one | 80.1749 | NA | NA | NA | NA | NA | NA | 16977 | 16977 | 10233 | 10233 |
| ENSMOCG00000003233 | 438.068184 | 0.2562827 | 0.0591407 | 0.0000007 | 0.0000149 | 101982023 | Homer1 | protein_coding | 101982023 | Homer1 | ENSMUSG00000007617 | Homer1 | ortholog_one2one | 93.7838 | ENSG00000152413 | HOMER1 | ortholog_one2one | 93.7838 | NA | NA | NA | NA | NA | NA | 26556 | 26556 | 9456 | 9456 |
| ENSMOCG00000012526 | 2820.952329 | 0.2943725 | 0.0700117 | 0.0000007 | 0.0000150 | 101995635 | Sgsm2 | protein_coding | 101995635 | Sgsm2 | ENSMUSG00000038351 | Sgsm2 | ortholog_one2one | 95.7143 | ENSG00000141258 | SGSM2 | ortholog_one2one | 93.4286 | NA | NA | NA | NA | NA | NA | 97761 | 97761 | 9905 | 9905 |
| ENSMOCG00000021403 | 141.240387 | -0.4828263 | 0.1276010 | 0.0000007 | 0.0000150 | 101991388 | Ppp1r14a | protein_coding | 101991388 | Ppp1r14a | ENSMUSG00000037166 | Ppp1r14a | ortholog_one2one | 70.0680 | ENSG00000167641 | PPP1R14A | ortholog_one2one | 85.0340 | NA | NA | NA | NA | NA | NA | 68458 | 68458 | 94274 | 94274 |
| ENSMOCG00000016851 | 78.350132 | -0.4088046 | 0.1064767 | 0.0000008 | 0.0000151 | 101984336 | Nkx2-2 | protein_coding | 101984336 | Nkx2-2 | ENSMUSG00000027434 | Nkx2-2 | ortholog_one2one | 98.5348 | ENSG00000125820 | NKX2-2 | ortholog_one2one | 98.1685 | NA | NA | NA | NA | NA | NA | 18088 | 18088 | 4821 | 4821 |
| ENSMOCG00000010463 | 74.319225 | -0.4312080 | 0.1133177 | 0.0000008 | 0.0000152 | 101999625 | Cdc7 | protein_coding | 101999625 | Cdc7 | ENSMUSG00000029283 | Cdc7 | ortholog_one2one | 84.9732 | ENSG00000097046 | CDC7 | ortholog_one2one | 81.5742 | NA | NA | NA | NA | NA | NA | 12545 | 12545 | 8317 | 8317 |
| ENSMOCG00000016398 | 77.750308 | -1.0555152 | 0.2870842 | 0.0000008 | 0.0000156 | 101986421 | protein_coding | 101986421 | NA | ENSG00000213213 | CCDC183 | ortholog_one2one | 78.2772 | NA | NA | NA | NA | NA | NA | NA | NA | 84960 | 84960 | |||||
| ENSMOCG00000020174 | 303.441973 | -0.3372619 | 0.0837716 | 0.0000008 | 0.0000157 | 101996879 | Paqr7 | protein_coding | 101996879 | Paqr7 | ENSMUSG00000037348 | Paqr7 | ortholog_one2one | 91.8841 | ENSG00000182749 | PAQR7 | ortholog_one2one | 85.2174 | NA | NA | NA | NA | NA | NA | 71904 | 71904 | 164091 | 164091 |
| ENSMOCG00000013709 | 101.860722 | -0.3626902 | 0.0923446 | 0.0000008 | 0.0000165 | 101994500 | Mcc | protein_coding | 101994500 | Mcc | ENSMUSG00000071856 | Mcc | ortholog_one2one | 95.6132 | ENSG00000171444 | MCC | ortholog_one2one | 94.0179 | NA | NA | NA | NA | NA | NA | 328949 | 328949 | 4163 | 4163 |
| ENSMOCG00000015215 | 17.153288 | -1.1214167 | 0.3174566 | 0.0000009 | 0.0000176 | 101990584 | protein_coding | 101990584 | ENSMUSG00000015787 | Abo | ortholog_one2many | 74.1667 | ENSG00000175164 | ABO | ortholog_one2many | 68.0556 | NA | NA | NA | NA | NA | NA | 80908 | 80908 | 28 | 28 | ||
| ENSMOCG00000017004 | 2183.420345 | 0.2841119 | 0.0677360 | 0.0000009 | 0.0000178 | 101992505 | Syt6 | protein_coding | 101992505 | Syt6 | ENSMUSG00000027849 | Syt6 | ortholog_one2one | 97.0817 | ENSG00000134207 | SYT6 | ortholog_one2one | 95.1362 | NA | NA | NA | NA | NA | NA | 54524 | 54524 | 148281 | 148281 |
| ENSMOCG00000001842 | 107.763796 | -0.2793430 | 0.0663429 | 0.0000009 | 0.0000179 | 101986409 | Caprin2 | protein_coding | 101986409 | Caprin2 | ENSMUSG00000030309 | Caprin2 | ortholog_one2one | 84.3040 | ENSG00000110888 | CAPRIN2 | ortholog_one2one | 78.6772 | NA | NA | NA | NA | NA | NA | 232560 | 232560 | 65981 | 65981 |
| ENSMOCG00000016200 | 15771.470879 | 0.2586792 | 0.0605014 | 0.0000009 | 0.0000180 | 102000616 | Ddn | protein_coding | 102000616 | Ddn | ENSMUSG00000059213 | Ddn | ortholog_one2one | 86.0399 | ENSG00000181418 | DDN | ortholog_one2one | 77.7778 | NA | NA | NA | NA | NA | NA | 13199 | 13199 | 23109 | 23109 |
| ENSMOCG00000002553 | 11.778028 | -1.0642576 | 0.2950354 | 0.0000009 | 0.0000180 | 101986419 | protein_coding | 101986419 | NA | ENSG00000167523 | SPATA33 | ortholog_one2one | 53.6232 | NA | NA | NA | NA | NA | NA | NA | NA | 124045 | 124045 | |||||
| ENSMOCG00000014313 | 279.905685 | -0.3241393 | 0.0803654 | 0.0000009 | 0.0000183 | 101991110 | Hapln2 | protein_coding | 101991110 | Hapln2 | ENSMUSG00000004894 | Hapln2 | ortholog_one2one | 95.0147 | ENSG00000132702 | HAPLN2 | ortholog_one2one | 90.6158 | NA | NA | NA | NA | NA | NA | 73940 | 73940 | 60484 | 60484 |
| ENSMOCG00000011461 | 77.900743 | -0.4820878 | 0.1298178 | 0.0000010 | 0.0000192 | 101979037 | Rhov | protein_coding | 101979037 | Rhov | ENSMUSG00000034226 | Rhov | ortholog_one2one | 98.7288 | ENSG00000104140 | RHOV | ortholog_one2one | 97.8814 | NA | NA | NA | NA | NA | NA | 228543 | 228543 | 171177 | 171177 |
| ENSMOCG00000018726 | 128.091329 | -0.3313289 | 0.0829867 | 0.0000010 | 0.0000192 | 101999748 | Cnpy4 | protein_coding | 101999748 | Cnpy4 | ENSMUSG00000036968 | Cnpy4 | ortholog_one2one | 92.1488 | ENSG00000166997 | CNPY4 | ortholog_one2one | 83.8843 | NA | NA | NA | NA | NA | NA | 66455 | 66455 | 245812 | 245812 |
| ENSMOCG00000013518 | 3007.298436 | 0.2974443 | 0.0723851 | 0.0000010 | 0.0000203 | 101997673 | Syndig1l | protein_coding | 101997673 | Syndig1l | ENSMUSG00000071234 | Syndig1l | ortholog_one2one | 90.7173 | ENSG00000183379 | SYNDIG1L | ortholog_one2one | 88.1857 | NA | NA | NA | NA | NA | NA | 627191 | 627191 | 646658 | 646658 |
| ENSMOCG00000014383 | 338.777801 | 0.2704038 | 0.0643106 | 0.0000011 | 0.0000204 | 101999630 | Coro2a | protein_coding | 101999630 | Coro2a | ENSMUSG00000028337 | Coro2a | ortholog_one2one | 89.0110 | ENSG00000106789 | CORO2A | ortholog_one2one | 82.9670 | NA | NA | NA | NA | NA | NA | 107684 | 107684 | 7464 | 7464 |
| ENSMOCG00000000153 | 196.645230 | -0.2970927 | 0.0726140 | 0.0000011 | 0.0000216 | 101985905 | Plin3 | protein_coding | 101985905 | Plin3 | ENSMUSG00000024197 | Plin3 | ortholog_one2one | 88.1279 | ENSG00000105355 | PLIN3 | ortholog_one2one | 77.8539 | NA | NA | NA | NA | NA | NA | 66905 | 66905 | 10226 | 10226 |
| ENSMOCG00000019151 | 114.303393 | 0.3302374 | 0.0833258 | 0.0000011 | 0.0000216 | 101997379 | Plekha2 | protein_coding | 101997379 | Plekha2 | ENSMUSG00000031557 | Plekha2 | ortholog_one2one | 93.8679 | ENSG00000169499 | PLEKHA2 | ortholog_one2one | 89.3868 | NA | NA | NA | NA | NA | NA | 83436 | 83436 | 59339 | 59339 |
| ENSMOCG00000014250 | 20.668134 | -0.9365493 | 0.2519802 | 0.0000011 | 0.0000218 | 101992779 | Lgr5 | protein_coding | 101992779 | Lgr5 | ENSMUSG00000020140 | Lgr5 | ortholog_one2one | 91.1894 | ENSG00000139292 | LGR5 | ortholog_one2one | 86.6740 | NA | NA | NA | NA | NA | NA | 14160 | 14160 | 8549 | 8549 |
| ENSMOCG00000017652 | 503.244888 | 0.3316443 | 0.0840787 | 0.0000012 | 0.0000227 | 102000957 | Kcnv1 | protein_coding | 102000957 | Kcnv1 | ENSMUSG00000022342 | Kcnv1 | ortholog_one2one | 99.2048 | ENSG00000164794 | KCNV1 | ortholog_one2one | 95.4274 | NA | NA | NA | NA | NA | NA | 67498 | 67498 | 27012 | 27012 |
| ENSMOCG00000022544 | 246.123212 | -0.2770203 | 0.0668063 | 0.0000012 | 0.0000231 | 101999594 | Insyn2b | protein_coding | 101999594 | Insyn2b | ENSMUSG00000069911 | Insyn2b | ortholog_one2one | 87.8505 | ENSG00000204767 | INSYN2B | ortholog_one2one | 76.0748 | NA | NA | NA | NA | NA | NA | 574403 | 574403 | 100131897 | 100131897 |
| ENSMOCG00000012945 | 122.221353 | 0.4788636 | 0.1312851 | 0.0000013 | 0.0000242 | 101999231 | Il17rd | protein_coding | 101999231 | Il17rd | ENSMUSG00000040717 | Il17rd | ortholog_one2one | 88.2432 | ENSG00000144730 | IL17RD | ortholog_one2one | 87.2973 | NA | NA | NA | NA | NA | NA | 171463 | 171463 | 54756 | 54756 |
| ENSMOCG00000006373 | 65.328952 | 0.4823115 | 0.1325215 | 0.0000013 | 0.0000248 | NA | protein_coding | NA | NA | ENSG00000197714 | ZNF460 | ortholog_one2one | 51.0753 | NA | NA | NA | NA | NA | NA | NA | NA | 10794 | 10794 | |||||
| ENSMOCG00000016996 | 190.012441 | -0.2914604 | 0.0716436 | 0.0000014 | 0.0000252 | 101982346 | Acsf3 | protein_coding | 101982346 | Acsf3 | ENSMUSG00000015016 | Acsf3 | ortholog_one2one | 90.0697 | ENSG00000176715 | ACSF3 | ortholog_one2one | 79.9652 | NA | NA | NA | NA | NA | NA | 257633 | 257633 | 197322 | 197322 |
| ENSMOCG00000004940 | 341.814850 | 0.2788282 | 0.0677709 | 0.0000014 | 0.0000252 | 101987516 | Abcb1a | protein_coding | 101987516 | Abcb1a | ENSMUSG00000040584 | Abcb1a | ortholog_one2one | 91.8431 | ENSG00000085563 | ABCB1 | ortholog_one2many | 87.6078 | NA | NA | NA | NA | NA | NA | 18671 | 18671 | 5243 | 5243 |
| ENSMOCG00000019392 | 322.403951 | -0.2541106 | 0.0606230 | 0.0000014 | 0.0000254 | 101993109 | Laptm4b | protein_coding | 101993109 | Laptm4b | ENSMUSG00000022257 | Laptm4b | ortholog_one2one | 92.5110 | ENSG00000104341 | LAPTM4B | ortholog_one2one | 90.3084 | NA | NA | NA | NA | NA | NA | 114128 | 114128 | 55353 | 55353 |
| ENSMOCG00000008266 | 19.860718 | -1.3406614 | 0.4316170 | 0.0000014 | 0.0000255 | 101987906 | Ccin | protein_coding | 101987906 | Ccin | ENSMUSG00000070999 | Ccin | ortholog_one2one | 97.1088 | ENSG00000185972 | CCIN | ortholog_one2one | 92.3469 | NA | NA | NA | NA | NA | NA | 442829 | 442829 | 881 | 881 |
| ENSMOCG00000013808 | 273.329192 | 0.3059079 | 0.0763143 | 0.0000014 | 0.0000255 | 101979592 | Mrpl48 | protein_coding | 101979592 | Mrpl48 | ENSMUSG00000030706 | Mrpl48 | ortholog_one2one | 95.5752 | ENSG00000175581 | MRPL48 | ortholog_one2one | 87.6106 | NA | NA | NA | NA | NA | NA | 52443 | 52443 | 51642 | 51642 |
| ENSMOCG00000012342 | 346.029999 | 0.2858332 | 0.0700218 | 0.0000014 | 0.0000258 | 101981299 | Cables1 | protein_coding | 101981299 | Cables1 | ENSMUSG00000040957 | Cables1 | ortholog_one2one | 90.2027 | ENSG00000134508 | CABLES1 | ortholog_one2one | 85.8108 | NA | NA | NA | NA | NA | NA | 63955 | 63955 | 91768 | 91768 |
| ENSMOCG00000002966 | 66.411044 | 0.5029294 | 0.1391105 | 0.0000015 | 0.0000270 | 101991643 | Myof | protein_coding | 101991643 | Myof | ENSMUSG00000048612 | Myof | ortholog_one2one | 96.6292 | ENSG00000138119 | MYOF | ortholog_one2one | 93.7958 | NA | NA | NA | NA | NA | NA | 226101 | 226101 | 26509 | 26509 |
| ENSMOCG00000006589 | 332.183001 | 0.2790964 | 0.0683136 | 0.0000015 | 0.0000278 | NA | Kremen1 | protein_coding | NA | Kremen1 | ENSMUSG00000020393 | Kremen1 | ortholog_one2one | 96.0089 | ENSG00000183762 | KREMEN1 | ortholog_one2one | 89.3570 | NA | NA | NA | NA | NA | NA | 84035 | 84035 | 83999 | 83999 |
| ENSMOCG00000022453 | 5925.818672 | 0.2730944 | 0.0665767 | 0.0000015 | 0.0000281 | 101979976 | Arhgap33 | protein_coding | 101979976 | Arhgap33 | ENSMUSG00000036882 | Arhgap33 | ortholog_one2one | 94.3382 | ENSG00000004777 | ARHGAP33 | ortholog_one2one | 88.7529 | NA | NA | NA | NA | NA | NA | 233071 | 233071 | 115703 | 115703 |
| ENSMOCG00000014152 | 105.976222 | -0.5200161 | 0.1441163 | 0.0000015 | 0.0000281 | 101985437 | Car14 | protein_coding | 101985437 | Car14 | ENSMUSG00000038526 | Car14 | ortholog_one2one | 91.3947 | ENSG00000118298 | CA14 | ortholog_one2one | 83.3828 | NA | NA | NA | NA | NA | NA | 23831 | 23831 | 23632 | 23632 |
| ENSMOCG00000006006 | 301.504893 | 0.3295868 | 0.0847926 | 0.0000015 | 0.0000281 | 101982629 | Slc40a1 | protein_coding | 101982629 | Slc40a1 | ENSMUSG00000025993 | Slc40a1 | ortholog_one2one | 93.2056 | ENSG00000138449 | SLC40A1 | ortholog_one2one | 89.0244 | NA | NA | NA | NA | NA | NA | 53945 | 53945 | 30061 | 30061 |
| ENSMOCG00000013411 | 73.779570 | -0.4199751 | 0.1156060 | 0.0000016 | 0.0000289 | 101992875 | Odf2l | protein_coding | 101992875 | Odf2l | ENSMUSG00000028256 | Odf2l | ortholog_one2one | 84.7352 | ENSG00000122417 | ODF2L | ortholog_one2one | 76.0125 | NA | NA | NA | NA | NA | NA | 52184 | 52184 | 57489 | 57489 |
| ENSMOCG00000018730 | 273.484711 | -0.2659711 | 0.0647070 | 0.0000016 | 0.0000294 | 101993004 | Sstr1 | protein_coding | 101993004 | Sstr1 | ENSMUSG00000035431 | Sstr1 | ortholog_one2one | 98.9770 | ENSG00000139874 | SSTR1 | ortholog_one2one | 98.4655 | NA | NA | NA | NA | NA | NA | 20605 | 20605 | 6751 | 6751 |
| ENSMOCG00000006475 | 103.654590 | 0.8600479 | 0.2344662 | 0.0000017 | 0.0000296 | 101998268 | Sfrp2 | protein_coding | 101998268 | Sfrp2 | ENSMUSG00000027996 | Sfrp2 | ortholog_one2one | 99.6610 | ENSG00000145423 | SFRP2 | ortholog_one2one | 98.3051 | NA | NA | NA | NA | NA | NA | 20319 | 20319 | 6423 | 6423 |
| ENSMOCG00000014373 | 8.352500 | -2.2183014 | 0.8572868 | 0.0000017 | 0.0000296 | NA | protein_coding | NA | ENSMUSG00000059070 | Rpl18 | ortholog_one2many | 95.5307 | ENSG00000063177 | RPL18 | ortholog_one2many | 92.7374 | NA | NA | NA | NA | NA | NA | 19899 | 19899 | 6141 | 6141 | ||
| ENSMOCG00000021168 | 332.798409 | -0.2559711 | 0.0619209 | 0.0000017 | 0.0000300 | 101992034 | Gdpd2 | protein_coding | 101992034 | Gdpd2 | ENSMUSG00000019359 | Gdpd2 | ortholog_one2one | 88.6617 | ENSG00000130055 | GDPD2 | ortholog_one2one | 81.9703 | NA | NA | NA | NA | NA | NA | 71584 | 71584 | 54857 | 54857 |
| ENSMOCG00000021354 | 137.197883 | 0.2965001 | 0.0743808 | 0.0000017 | 0.0000307 | NA | Cntn5 | protein_coding | NA | Cntn5 | ENSMUSG00000039488 | Cntn5 | ortholog_one2one | 95.1848 | ENSG00000149972 | CNTN5 | ortholog_one2one | 91.0414 | NA | NA | NA | NA | NA | NA | 244682 | 244682 | 53942 | 53942 |
| ENSMOCG00000011074 | 124.556183 | -0.3302208 | 0.0859711 | 0.0000018 | 0.0000322 | 102001629 | Lrp5 | protein_coding | 102001629 | Lrp5 | ENSMUSG00000024913 | Lrp5 | ortholog_one2one | 98.0745 | ENSG00000162337 | LRP5 | ortholog_one2one | 94.5963 | NA | NA | NA | NA | NA | NA | 16973 | 16973 | 4041 | 4041 |
| ENSMOCG00000015816 | 51.096558 | -0.5698542 | 0.1586500 | 0.0000018 | 0.0000322 | 101979664 | Arhgef19 | protein_coding | 101979664 | Arhgef19 | ENSMUSG00000028919 | Arhgef19 | ortholog_one2one | 93.5162 | ENSG00000142632 | ARHGEF19 | ortholog_one2one | 85.7855 | NA | NA | NA | NA | NA | NA | 213649 | 213649 | 128272 | 128272 |
| ENSMOCG00000012722 | 266.892033 | -0.3858903 | 0.1056089 | 0.0000019 | 0.0000335 | 101992568 | protein_coding | 101992568 | ENSMUSG00000042750 | Bex2 | ortholog_many2many | 84.2520 | ENSG00000133169 | BEX1 | ortholog_many2many | 71.6535 | ENSMUSG00000042750, ENSMUSG00000042750, ENSMUSG00000050071, ENSMUSG00000050071 | Bex2, Bex2, Bex1, Bex1 | 84.252, 84.252, 77.9528, 77.9528 | ENSG00000133169, ENSG00000133169, ENSG00000133134, ENSG00000133134 | BEX1, BEX1, BEX2, BEX2 | 71.6535, 71.6535, 71.6535, 71.6535 | 12069 | 12069 | 55859 | 55859 | ||
| ENSMOCG00000010093 | 60.657950 | 0.5988802 | 0.1668548 | 0.0000020 | 0.0000348 | NA | Snord47 | snoRNA | NA | Snord47 | ENSMUSG00000064968 | Snord47 | ortholog_one2one | 92.3077 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | |||
| ENSMOCG00000018160 | 166.418615 | -0.5311904 | 0.1499270 | 0.0000020 | 0.0000348 | 101981215 | Nrp2 | protein_coding | 101981215 | Nrp2 | ENSMUSG00000025969 | Nrp2 | ortholog_one2one | 96.4363 | ENSG00000118257 | NRP2 | ortholog_one2one | 94.6004 | NA | NA | NA | NA | NA | NA | 18187 | 18187 | 8828 | 8828 |
| ENSMOCG00000002108 | 503.173838 | -0.2610605 | 0.0640338 | 0.0000020 | 0.0000348 | 101986189 | protein_coding | 101986189 | ENSMUSG00000025287 | Acot9 | ortholog_one2many | 88.6364 | ENSG00000123130 | ACOT9 | ortholog_one2one | 84.7727 | ENSMUSG00000025287, ENSMUSG00000047565 | Acot9, Acot10 | 88.6364, 86.8182 | ENSG00000123130, ENSG00000123130 | ACOT9, ACOT9 | 84.7727, 84.7727 | 56360 | 56360 | 23597 | 23597 | ||
| ENSMOCG00000003197 | 32.878605 | -0.4769859 | 0.1351277 | 0.0000020 | 0.0000351 | 101995363 | Ldlrap1 | protein_coding | 101995363 | Ldlrap1 | ENSMUSG00000037295 | Ldlrap1 | ortholog_one2one | 94.7883 | ENSG00000157978 | LDLRAP1 | ortholog_one2one | 87.9479 | NA | NA | NA | NA | NA | NA | 100017 | 100017 | 26119 | 26119 |
| ENSMOCG00000012137 | 94.437126 | -0.8164052 | 0.2248792 | 0.0000020 | 0.0000352 | 101986547 | Arhgap36 | protein_coding | 101986547 | Arhgap36 | ENSMUSG00000036198 | Arhgap36 | ortholog_one2one | 81.4672 | ENSG00000147256 | ARHGAP36 | ortholog_one2one | 78.5714 | NA | NA | NA | NA | NA | NA | 75404 | 75404 | 158763 | 158763 |
| ENSMOCG00000022613 | 259.039472 | 0.2550306 | 0.0623825 | 0.0000021 | 0.0000356 | 101985752 | Rpusd3 | protein_coding | 101985752 | Rpusd3 | ENSMUSG00000051169 | Rpusd3 | ortholog_one2one | 84.5930 | ENSG00000156990 | RPUSD3 | ortholog_one2one | 72.0930 | NA | NA | NA | NA | NA | NA | 101122 | 101122 | 285367 | 285367 |
| ENSMOCG00000006246 | 45.903406 | 0.6061103 | 0.1691807 | 0.0000021 | 0.0000358 | NA | SNORD81 | snoRNA | NA | SNORD81 | ENSMUSG00000065228 | Gm25789 | ortholog_one2many | 90.9091 | ENSG00000202023 | SNORD81 | ortholog_one2many | 85.7143 | ENSMUSG00000065228, ENSMUSG00000065228, ENSMUSG00000065228, ENSMUSG00000064573, ENSMUSG00000064573, ENSMUSG00000064573 | Gm25789, Gm25789, Gm25789, Gm25802, Gm25802, Gm25802 | 90.9091, 90.9091, 90.9091, 87.013, 87.013, 87.013 | ENSG00000202023, ENSG00000202023, ENSG00000199934, ENSG00000199934, ENSG00000212278, ENSG00000212278 | SNORD81, SNORD81, SNORD81, SNORD81, SNORD81, SNORD81 | 85.7143, 85.7143, 84.4156, 84.4156, 72.7273, 72.7273 | 115487640 | 115487640 | 124900235 | 124900235 |
| ENSMOCG00000009101 | 505.040390 | -0.3596112 | 0.0971009 | 0.0000021 | 0.0000361 | 101997876 | Plekhh1 | protein_coding | 101997876 | Plekhh1 | ENSMUSG00000060716 | Plekhh1 | ortholog_one2one | 91.3717 | ENSG00000054690 | PLEKHH1 | ortholog_one2one | 83.5546 | NA | NA | NA | NA | NA | NA | 211945 | 211945 | 57475 | 57475 |
| ENSMOCG00000001571 | 913.214873 | -0.2763687 | 0.0689839 | 0.0000022 | 0.0000371 | 102000272 | Enpp2 | protein_coding | 102000272 | Enpp2 | ENSMUSG00000022425 | Enpp2 | ortholog_one2one | 96.4989 | ENSG00000136960 | ENPP2 | ortholog_one2one | 89.0591 | NA | NA | NA | NA | NA | NA | 18606 | 18606 | 5168 | 5168 |
| ENSMOCG00000019650 | 106.992408 | -0.3693793 | 0.1007877 | 0.0000022 | 0.0000372 | 101999954 | Tmem98 | protein_coding | 101999954 | Tmem98 | ENSMUSG00000035413 | Tmem98 | ortholog_one2one | 99.5575 | ENSG00000006042 | TMEM98 | ortholog_one2one | 98.6726 | NA | NA | NA | NA | NA | NA | 103743 | 103743 | 26022 | 26022 |
| ENSMOCG00000004075 | 329.257725 | 0.2781419 | 0.0696524 | 0.0000022 | 0.0000378 | 101980468 | Zfp341 | protein_coding | 101980468 | Zfp341 | ENSMUSG00000059842 | Zfp341 | ortholog_one2one | 96.5680 | ENSG00000131061 | ZNF341 | ortholog_one2one | 90.5325 | NA | NA | NA | NA | NA | NA | 228807 | 228807 | 84905 | 84905 |
| ENSMOCG00000010505 | 17.685967 | 0.8163389 | 0.2273565 | 0.0000023 | 0.0000386 | NA | Spata32 | protein_coding | NA | Spata32 | ENSMUSG00000044787 | Spata32 | ortholog_one2one | 70.6949 | ENSG00000184361 | SPATA32 | ortholog_one2one | 42.9003 | NA | NA | NA | NA | NA | NA | 328019 | 328019 | 124783 | 124783 |
| ENSMOCG00000001112 | 137.495138 | -0.2509928 | 0.0616607 | 0.0000023 | 0.0000393 | 101991490 | Zbtb5 | protein_coding | 101991490 | Zbtb5 | ENSMUSG00000049657 | Zbtb5 | ortholog_one2one | 95.8209 | ENSG00000168795 | ZBTB5 | ortholog_one2one | 93.5821 | NA | NA | NA | NA | NA | NA | 230119 | 230119 | 9925 | 9925 |
| ENSMOCG00000000805 | 292.704487 | -0.3205704 | 0.0840769 | 0.0000024 | 0.0000399 | 101988586 | Fa2h | protein_coding | 101988586 | Fa2h | ENSMUSG00000033579 | Fa2h | ortholog_one2one | 91.3979 | ENSG00000103089 | FA2H | ortholog_one2one | 84.9462 | NA | NA | NA | NA | NA | NA | 338521 | 338521 | 79152 | 79152 |
| ENSMOCG00000008741 | 154.943485 | 0.2610451 | 0.0647018 | 0.0000024 | 0.0000401 | 101999974 | protein_coding | 101999974 | NA | ENSG00000197312 | DDI2 | ortholog_one2one | 94.5137 | NA | NA | NA | NA | NA | NA | NA | NA | 84301 | 84301 | |||||
| ENSMOCG00000016833 | 294.155890 | 0.2535968 | 0.0625098 | 0.0000024 | 0.0000401 | NA | protein_coding | NA | ENSMUSG00000039375 | Wdr17 | ortholog_one2one | 90.6504 | ENSG00000150627 | WDR17 | ortholog_one2one | 86.1789 | NA | NA | NA | NA | NA | NA | 244484 | 244484 | 116966 | 116966 | ||
| ENSMOCG00000013748 | 66.605504 | -1.0471148 | 0.3212985 | 0.0000025 | 0.0000416 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000001873 | 100.369300 | 0.2870765 | 0.0730565 | 0.0000025 | 0.0000418 | 101999035 | Zbtb41 | protein_coding | 101999035 | Zbtb41 | ENSMUSG00000033964 | Zbtb41 | ortholog_one2one | 95.9296 | ENSG00000177888 | ZBTB41 | ortholog_one2one | 93.7294 | NA | NA | NA | NA | NA | NA | 226470 | 226470 | 360023 | 360023 |
| ENSMOCG00000018061 | 16.418829 | -2.8360859 | 1.1954505 | 0.0000025 | 0.0000419 | 101997333 | Tekt5 | protein_coding | 101997333 | Tekt5 | ENSMUSG00000039179 | Tekt5 | ortholog_one2one | 83.3632 | ENSG00000153060 | TEKT5 | ortholog_one2one | 73.5241 | NA | NA | NA | NA | NA | NA | 70426 | 70426 | 146279 | 146279 |
| ENSMOCG00000018799 | 263.675829 | 0.3020873 | 0.0780863 | 0.0000025 | 0.0000420 | 101991108 | Hapln1 | protein_coding | 101991108 | Hapln1 | ENSMUSG00000021613 | Hapln1 | ortholog_one2one | 98.0226 | ENSG00000145681 | HAPLN1 | ortholog_one2one | 95.1977 | NA | NA | NA | NA | NA | NA | 12950 | 12950 | 1404 | 1404 |
| ENSMOCG00000004791 | 69.975931 | -0.6177696 | 0.1751139 | 0.0000026 | 0.0000427 | 101983755 | Grik1 | protein_coding | 101983755 | Grik1 | ENSMUSG00000022935 | Grik1 | ortholog_one2one | 99.0364 | ENSG00000171189 | GRIK1 | ortholog_one2one | 97.4304 | NA | NA | NA | NA | NA | NA | 14805 | 14805 | 2897 | 2897 |
| ENSMOCG00000022770 | 226.776622 | -0.4792656 | 0.1383297 | 0.0000026 | 0.0000429 | 101991883 | Cadps2 | protein_coding | 101991883 | Cadps2 | ENSMUSG00000017978 | Cadps2 | ortholog_one2one | 98.2308 | ENSG00000081803 | CADPS2 | ortholog_one2one | 95.6154 | NA | NA | NA | NA | NA | NA | 320405 | 320405 | 93664 | 93664 |
| ENSMOCG00000017569 | 139.392941 | -0.2855552 | 0.0729111 | 0.0000027 | 0.0000444 | 102002292 | Micall1 | protein_coding | 102002292 | Micall1 | ENSMUSG00000033039 | Micall1 | ortholog_one2one | 88.8889 | ENSG00000100139 | MICALL1 | ortholog_one2one | 82.2695 | NA | NA | NA | NA | NA | NA | 27008 | 27008 | 85377 | 85377 |
| ENSMOCG00000011897 | 2348.716239 | 0.2507214 | 0.0623207 | 0.0000028 | 0.0000460 | 101986407 | Rcn1 | protein_coding | 101986407 | Rcn1 | ENSMUSG00000005973 | Rcn1 | ortholog_one2one | 97.5385 | ENSG00000049449 | RCN1 | ortholog_one2one | 94.7692 | NA | NA | NA | NA | NA | NA | 19672 | 19672 | 5954 | 5954 |
| ENSMOCG00000020100 | 53.110518 | 0.5217511 | 0.1514460 | 0.0000028 | 0.0000462 | 101996373 | Slc25a24 | protein_coding | 101996373 | Slc25a24 | ENSMUSG00000040322 | Slc25a24 | ortholog_one2one | 96.4211 | ENSG00000085491 | SLC25A24 | ortholog_one2one | 92.6316 | NA | NA | NA | NA | NA | NA | 229731 | 229731 | 29957 | 29957 |
| ENSMOCG00000020925 | 91.039846 | 0.3659415 | 0.1016449 | 0.0000029 | 0.0000471 | 102001314 | Nrn1l | protein_coding | 102001314 | Nrn1l | ENSMUSG00000044287 | Nrn1l | ortholog_one2one | 93.1677 | ENSG00000188038 | NRN1L | ortholog_one2one | 78.2609 | NA | NA | NA | NA | NA | NA | 234700 | 234700 | 123904 | 123904 |
| ENSMOCG00000012547 | 113.216363 | -0.3004778 | 0.0782904 | 0.0000029 | 0.0000472 | 101983964 | Cptp | protein_coding | 101983964 | Cptp | ENSMUSG00000029073 | Cptp | ortholog_one2one | 83.7963 | ENSG00000224051 | CPTP | ortholog_one2one | 76.3889 | NA | NA | NA | NA | NA | NA | 79554 | 79554 | 80772 | 80772 |
| ENSMOCG00000000894 | 108.034307 | 0.6057978 | 0.1739842 | 0.0000029 | 0.0000473 | 101986986 | protein_coding | 101986986 | ENSMUSG00000030361 | Klrb1a | ortholog_many2many | 61.8182 | ENSG00000111796 | KLRB1 | ortholog_one2many | 45.9091 | ENSMUSG00000030361, ENSMUSG00000030325, ENSMUSG00000079298 | Klrb1a, Klrb1c, Klrb1b | 61.8182, 57.2727, 50.4545 | ENSG00000111796, ENSG00000111796, ENSG00000111796 | KLRB1, KLRB1, KLRB1 | 45.9091, 45.9091, 45.9091 | 17057 | 17057 | 3820 | 3820 | ||
| ENSMOCG00000020436 | 125.564212 | -0.4492062 | 0.1304661 | 0.0000030 | 0.0000478 | 101996403 | Ccdc40 | protein_coding | 101996403 | Ccdc40 | ENSMUSG00000039963 | Ccdc40 | ortholog_one2one | 74.1468 | ENSG00000141519 | CCDC40 | ortholog_one2one | 58.8737 | NA | NA | NA | NA | NA | NA | 207607 | 207607 | 55036 | 55036 |
| ENSMOCG00000005813 | 189.522481 | -0.3246995 | 0.0869506 | 0.0000030 | 0.0000483 | 101998326 | Igsf3 | protein_coding | 101998326 | Igsf3 | ENSMUSG00000042035 | Igsf3 | ortholog_one2one | 96.1345 | ENSG00000143061 | IGSF3 | ortholog_one2one | 92.8571 | NA | NA | NA | NA | NA | NA | 78908 | 78908 | 3321 | 3321 |
| ENSMOCG00000021359 | 382.863485 | 0.3025286 | 0.0792903 | 0.0000031 | 0.0000494 | 101979131 | Oprk1 | protein_coding | 101979131 | Oprk1 | ENSMUSG00000025905 | Oprk1 | ortholog_one2one | 94.4737 | ENSG00000082556 | OPRK1 | ortholog_one2one | 92.6316 | NA | NA | NA | NA | NA | NA | 18387 | 18387 | 4986 | 4986 |
| ENSMOCG00000011577 | 299.825760 | -0.2616468 | 0.0661569 | 0.0000032 | 0.0000517 | 101979601 | Tmem145 | protein_coding | 101979601 | Tmem145 | ENSMUSG00000043843 | Tmem145 | ortholog_one2one | 87.4336 | ENSG00000167619 | TMEM145 | ortholog_one2one | 81.0620 | NA | NA | NA | NA | NA | NA | 330485 | 330485 | 284339 | 284339 |
| ENSMOCG00000001943 | 230.608059 | -0.4815072 | 0.1417155 | 0.0000033 | 0.0000531 | 101997257 | protein_coding | 101997257 | ENSMUSG00000024747 | Aldh1a7 | ortholog_one2many | 86.7416 | ENSG00000165092 | ALDH1A1 | ortholog_one2many | 80.4494 | NA | NA | NA | NA | NA | NA | 26358 | 26358 | 216 | 216 | ||
| ENSMOCG00000002631 | 85.283463 | -0.9855055 | 0.3043516 | 0.0000033 | 0.0000531 | 101997770 | protein_coding | 101997770 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000005578 | 16215.574853 | -0.3334726 | 0.0908728 | 0.0000034 | 0.0000536 | 101987377 | Plp1 | protein_coding | 101987377 | Plp1 | ENSMUSG00000031425 | Plp1 | ortholog_one2one | 99.6390 | ENSG00000123560 | PLP1 | ortholog_one2one | 99.6390 | NA | NA | NA | NA | NA | NA | 18823 | 18823 | 5354 | 5354 |
| ENSMOCG00000020102 | 1064.398752 | -0.2914511 | 0.0760594 | 0.0000034 | 0.0000541 | 101986973 | Dner | protein_coding | 101986973 | Dner | ENSMUSG00000036766 | Dner | ortholog_one2one | 94.8440 | ENSG00000187957 | DNER | ortholog_one2one | 89.5522 | NA | NA | NA | NA | NA | NA | 227325 | 227325 | 92737 | 92737 |
| ENSMOCG00000011758 | 19.763260 | -0.9485418 | 0.2887533 | 0.0000034 | 0.0000543 | 101993645 | Prss56 | protein_coding | 101993645 | Prss56 | ENSMUSG00000036480 | Prss56 | ortholog_one2one | 89.1486 | ENSG00000237412 | PRSS56 | ortholog_one2one | 79.6327 | NA | NA | NA | NA | NA | NA | 69453 | 69453 | 646960 | 646960 |
| ENSMOCG00000018532 | 324.818477 | 0.2746991 | 0.0705735 | 0.0000034 | 0.0000545 | 101993487 | Csrnp3 | protein_coding | 101993487 | Csrnp3 | ENSMUSG00000044647 | Csrnp3 | ortholog_one2one | 96.3211 | ENSG00000178662 | CSRNP3 | ortholog_one2one | 92.4749 | NA | NA | NA | NA | NA | NA | 77771 | 77771 | 80034 | 80034 |
| ENSMOCG00000017591 | 19.856935 | -0.7159929 | 0.2069007 | 0.0000036 | 0.0000564 | 101992545 | Togaram2 | protein_coding | 101992545 | Togaram2 | ENSMUSG00000045761 | Togaram2 | ortholog_one2one | 85.7858 | ENSG00000189350 | TOGARAM2 | ortholog_one2one | 72.4725 | NA | NA | NA | NA | NA | NA | 320159 | 320159 | 165186 | 165186 |
| ENSMOCG00000003450 | 71.528080 | -0.3389941 | 0.0934998 | 0.0000037 | 0.0000578 | 101987123 | Tmc7 | protein_coding | 101987123 | Tmc7 | ENSMUSG00000042246 | Tmc7 | ortholog_one2one | 95.7241 | ENSG00000170537 | TMC7 | ortholog_one2one | 90.2069 | NA | NA | NA | NA | NA | NA | 209760 | 209760 | 79905 | 79905 |
| ENSMOCG00000004217 | 19.869416 | -0.7300063 | 0.2119070 | 0.0000037 | 0.0000585 | NA | misc_RNA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000018206 | 138.482480 | -0.2572029 | 0.0654835 | 0.0000038 | 0.0000591 | 101988771 | Lap3 | protein_coding | 101988771 | Lap3 | ENSMUSG00000039682 | Lap3 | ortholog_one2one | 94.7977 | ENSG00000002549 | LAP3 | ortholog_one2one | 90.7514 | NA | NA | NA | NA | NA | NA | 66988 | 66988 | 51056 | 51056 |
| ENSMOCG00000018193 | 81.111461 | -0.3767782 | 0.1077699 | 0.0000038 | 0.0000595 | 101980949 | Gsdme | protein_coding | 101980949 | Gsdme | ENSMUSG00000029821 | Gsdme | ortholog_one2one | 84.0864 | ENSG00000105928 | GSDME | ortholog_one2one | 72.1022 | NA | NA | NA | NA | NA | NA | 54722 | 54722 | 1687 | 1687 |
| ENSMOCG00000005019 | 132.244726 | -0.3727278 | 0.1064397 | 0.0000039 | 0.0000604 | 101979415 | Hspb6 | protein_coding | 101979415 | Hspb6 | ENSMUSG00000036854 | Hspb6 | ortholog_one2one | 95.0617 | ENSG00000004776 | HSPB6 | ortholog_one2one | 87.6543 | NA | NA | NA | NA | NA | NA | 243912 | 243912 | 126393 | 126393 |
| ENSMOCG00000003735 | 24.318186 | -0.9910876 | 0.3136665 | 0.0000039 | 0.0000608 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000019751 | 87.525535 | -0.3522128 | 0.0988931 | 0.0000039 | 0.0000609 | 101994009 | Zfp395 | protein_coding | 101994009 | Zfp395 | ENSMUSG00000034522 | Zfp395 | ortholog_one2one | 92.8287 | ENSG00000186918 | ZNF395 | ortholog_one2one | 82.4701 | NA | NA | NA | NA | NA | NA | 380912 | 380912 | 55893 | 55893 |
| ENSMOCG00000007505 | 36.850254 | -0.6140144 | 0.1810686 | 0.0000040 | 0.0000618 | 102000917 | Kcns3 | protein_coding | 102000917 | Kcns3 | ENSMUSG00000043673 | Kcns3 | ortholog_one2one | 97.5560 | ENSG00000170745 | KCNS3 | ortholog_one2one | 94.5010 | NA | NA | NA | NA | NA | NA | 238076 | 238076 | 3790 | 3790 |
| ENSMOCG00000015275 | 142.519936 | -0.3102756 | 0.0840429 | 0.0000043 | 0.0000665 | 102002681 | Decr1 | protein_coding | 102002681 | Decr1 | ENSMUSG00000028223 | Decr1 | ortholog_one2one | 91.6418 | ENSG00000104325 | DECR1 | ortholog_one2one | 82.0896 | NA | NA | NA | NA | NA | NA | 67460 | 67460 | 1666 | 1666 |
| ENSMOCG00000000534 | 23.956552 | -0.6469661 | 0.1914186 | 0.0000043 | 0.0000665 | NA | protein_coding | NA | ENSMUSG00000116673 | A630089N07Rik | ortholog_one2many | 32.4675 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | |||||
| ENSMOCG00000002573 | 244.381156 | -0.3395970 | 0.0952247 | 0.0000045 | 0.0000692 | 101980965 | Celf6 | protein_coding | 101980965 | Celf6 | ENSMUSG00000032297 | Celf6 | ortholog_one2one | 96.2578 | ENSG00000140488 | CELF6 | ortholog_one2one | 95.2183 | NA | NA | NA | NA | NA | NA | 76183 | 76183 | 60677 | 60677 |
| ENSMOCG00000016973 | 199.676964 | -0.2814535 | 0.0742687 | 0.0000046 | 0.0000701 | 101995862 | Gab2 | protein_coding | 101995862 | Gab2 | ENSMUSG00000004508 | Gab2 | ortholog_one2one | 95.7614 | ENSG00000033327 | GAB2 | ortholog_one2one | 94.3485 | NA | NA | NA | NA | NA | NA | 14389 | 14389 | 9846 | 9846 |
| ENSMOCG00000010236 | 465.246344 | -0.5137481 | 0.1555164 | 0.0000046 | 0.0000707 | 101991744 | Minar2 | protein_coding | 101991744 | Minar2 | ENSMUSG00000050875 | Minar2 | ortholog_one2one | 87.5648 | ENSG00000186367 | MINAR2 | ortholog_one2one | 76.1658 | NA | NA | NA | NA | NA | NA | 225583 | 225583 | 100127206 | 100127206 |
| ENSMOCG00000001205 | 116.088225 | -0.3806536 | 0.1112287 | 0.0000048 | 0.0000729 | 101991159 | Tmem125 | protein_coding | 101991159 | Tmem125 | ENSMUSG00000050854 | Tmem125 | ortholog_one2one | 92.1296 | ENSG00000179178 | TMEM125 | ortholog_one2one | 87.9630 | NA | NA | NA | NA | NA | NA | 230678 | 230678 | 128218 | 128218 |
| ENSMOCG00000022307 | 617.169785 | -0.2555771 | 0.0661244 | 0.0000049 | 0.0000740 | 101995523 | Flywch1 | protein_coding | 101995523 | Flywch1 | ENSMUSG00000040097 | Flywch1 | ortholog_one2one | 83.6582 | ENSG00000059122 | FLYWCH1 | ortholog_one2one | 69.4153 | NA | NA | NA | NA | NA | NA | 224613 | 224613 | 84256 | 84256 |
| ENSMOCG00000011853 | 24.520383 | -0.9081328 | 0.2855795 | 0.0000050 | 0.0000761 | NA | protein_coding | NA | ENSMUSG00000031340 | Gabre | ortholog_one2one | 82.6772 | ENSG00000102287 | GABRE | ortholog_one2one | 68.5039 | NA | NA | NA | NA | NA | NA | 14404 | 14404 | 2564 | 2564 | ||
| ENSMOCG00000012243 | 42.897888 | -0.4405414 | 0.1333377 | 0.0000051 | 0.0000764 | 101992840 | protein_coding | 101992840 | ENSMUSG00000020389 | Cdkl3 | ortholog_one2one | 100.0000 | ENSG00000006837 | CDKL3 | ortholog_one2one | 95.3125 | NA | NA | NA | NA | NA | NA | 213084 | 213084 | 51265 | 51265 | ||
| ENSMOCG00000000440 | 207.167252 | 0.2792443 | 0.0740504 | 0.0000051 | 0.0000764 | 101995459 | Trhde | protein_coding | 101995459 | Trhde | ENSMUSG00000050663 | Trhde | ortholog_one2one | 96.3938 | ENSG00000072657 | TRHDE | ortholog_one2one | 95.9064 | NA | NA | NA | NA | NA | NA | 237553 | 237553 | 29953 | 29953 |
| ENSMOCG00000012739 | 224.817753 | 0.3071735 | 0.0841393 | 0.0000052 | 0.0000787 | 101988770 | Kdm7a | protein_coding | 101988770 | Kdm7a | ENSMUSG00000042599 | Kdm7a | ortholog_one2one | 94.1302 | ENSG00000006459 | KDM7A | ortholog_one2one | 90.3949 | NA | NA | NA | NA | NA | NA | 338523 | 338523 | 80853 | 80853 |
| ENSMOCG00000020678 | 285.631756 | 0.3097280 | 0.0851414 | 0.0000053 | 0.0000793 | 101998543 | Tuba8 | protein_coding | 101998543 | Tuba8 | ENSMUSG00000030137 | Tuba8 | ortholog_one2one | 99.7773 | ENSG00000183785 | TUBA8 | ortholog_one2one | 99.1091 | NA | NA | NA | NA | NA | NA | 53857 | 53857 | 51807 | 51807 |
| ENSMOCG00000016642 | 697.840138 | -0.2857146 | 0.0765733 | 0.0000054 | 0.0000801 | 101999199 | Disp2 | protein_coding | 101999199 | Disp2 | ENSMUSG00000040035 | Disp2 | ortholog_one2one | 91.8033 | ENSG00000140323 | DISP2 | ortholog_one2one | 78.2414 | NA | NA | NA | NA | NA | NA | 214240 | 214240 | 85455 | 85455 |
| ENSMOCG00000014914 | 10.952332 | 1.0842563 | 0.3796644 | 0.0000054 | 0.0000803 | 101998599 | protein_coding | 101998599 | ENSMUSG00000021490 | Slc34a1 | ortholog_one2one | 95.3271 | ENSG00000131183 | SLC34A1 | ortholog_one2one | 92.2118 | NA | NA | NA | NA | NA | NA | 20505 | 20505 | 6569 | 6569 | ||
| ENSMOCG00000013879 | 90.636040 | -0.3057258 | 0.0838564 | 0.0000055 | 0.0000812 | 101979702 | Tfb1m | protein_coding | 101979702 | Tfb1m | ENSMUSG00000036983 | Tfb1m | ortholog_one2one | 91.5942 | ENSG00000029639 | TFB1M | ortholog_one2one | 83.1884 | NA | NA | NA | NA | NA | NA | 224481 | 224481 | 51106 | 51106 |
| ENSMOCG00000015445 | 91.903292 | -0.4035983 | 0.1210959 | 0.0000055 | 0.0000819 | 101983981 | Gjc2 | protein_coding | 101983981 | Gjc2 | ENSMUSG00000043448 | Gjc2 | ortholog_one2one | 96.2329 | ENSG00000198835 | GJC2 | ortholog_one2one | 85.9589 | NA | NA | NA | NA | NA | NA | 118454 | 118454 | 57165 | 57165 |
| ENSMOCG00000000058 | 686.713691 | -0.3574402 | 0.1037450 | 0.0000056 | 0.0000826 | 101980039 | Magel2 | protein_coding | 101980039 | Magel2 | ENSMUSG00000056972 | Magel2 | ortholog_one2one | 76.3052 | ENSG00000254585 | MAGEL2 | ortholog_one2one | 58.8755 | NA | NA | NA | NA | NA | NA | 27385 | 27385 | 54551 | 54551 |
| ENSMOCG00000020814 | 18.204010 | -0.7523968 | 0.2289506 | 0.0000057 | 0.0000833 | NA | Insc | protein_coding | NA | Insc | ENSMUSG00000048782 | Insc | ortholog_one2one | 96.8912 | ENSG00000188487 | INSC | ortholog_one2one | 86.5285 | NA | NA | NA | NA | NA | NA | 233752 | 233752 | 387755 | 387755 |
| ENSMOCG00000014712 | 231.315492 | -0.2721652 | 0.0722520 | 0.0000057 | 0.0000835 | NA | protein_coding | NA | ENSMUSG00000001313 | Rnd2 | ortholog_one2many | 99.1189 | ENSG00000108830 | RND2 | ortholog_one2many | 98.6784 | NA | NA | NA | NA | NA | NA | 11858 | 11858 | 8153 | 8153 | ||
| ENSMOCG00000013189 | 156.625413 | 0.2733670 | 0.0726545 | 0.0000057 | 0.0000835 | 101986401 | Sgk3 | protein_coding | 101986401 | Sgk3 | ENSMUSG00000025915 | Sgk3 | ortholog_one2one | 97.3822 | ENSG00000104205 | SGK3 | ortholog_one2one | 97.1204 | NA | NA | NA | NA | NA | NA | 170755 | 170755 | 23678 | 23678 |
| ENSMOCG00000013660 | 137.351121 | -0.6977902 | 0.2121001 | 0.0000058 | 0.0000846 | 101981610 | Gstm6 | protein_coding | 101981610 | Gstm6 | ENSMUSG00000068762 | Gstm6 | ortholog_one2one | 76.6055 | ENSG00000134184 | GSTM1 | ortholog_one2many | 79.8165 | NA | NA | NA | NA | NA | NA | 14867 | 14867 | 2944 | 2944 |
| ENSMOCG00000018083 | 54.558121 | 0.3579883 | 0.1042789 | 0.0000058 | 0.0000852 | 101982143 | Niban1 | protein_coding | 101982143 | Niban1 | ENSMUSG00000026483 | Niban1 | ortholog_one2one | 81.3853 | ENSG00000135842 | NIBAN1 | ortholog_one2one | 71.9697 | NA | NA | NA | NA | NA | NA | 63913 | 63913 | 116496 | 116496 |
| ENSMOCG00000007827 | 121.122477 | -0.3707460 | 0.1092995 | 0.0000059 | 0.0000859 | 101994740 | Snx8 | protein_coding | 101994740 | Snx8 | ENSMUSG00000029560 | Snx8 | ortholog_one2one | 97.3856 | ENSG00000106266 | SNX8 | ortholog_one2one | 89.3246 | NA | NA | NA | NA | NA | NA | 231834 | 231834 | 29886 | 29886 |
| ENSMOCG00000004382 | 175.945914 | -0.4040274 | 0.1223614 | 0.0000062 | 0.0000896 | 102001478 | Smim10l2a | protein_coding | 102001478 | Smim10l2a | ENSMUSG00000054850 | Smim10l2a | ortholog_one2one | 93.5897 | ENSG00000178947 | SMIM10L2A | ortholog_one2many | 89.7436 | ENSMUSG00000054850, ENSMUSG00000054850 | Smim10l2a, Smim10l2a | 93.5897, 93.5897 | ENSG00000178947, ENSG00000196972 | SMIM10L2A, SMIM10L2B | 89.7436, 89.7436 | 320237 | 320237 | 399668 | 399668 |
| ENSMOCG00000015335 | 50.479078 | -0.4177429 | 0.1274430 | 0.0000062 | 0.0000897 | NA | Accs | protein_coding | NA | Accs | ENSMUSG00000040272 | Accs | ortholog_one2one | 91.6493 | ENSG00000110455 | ACCS | ortholog_one2one | 82.8810 | NA | NA | NA | NA | NA | NA | 329470 | 329470 | 84680 | 84680 |
| ENSMOCG00000014246 | 176.403762 | -0.3189844 | 0.0898490 | 0.0000063 | 0.0000920 | 102001347 | Doc2a | protein_coding | 102001347 | Doc2a | ENSMUSG00000052301 | Doc2a | ortholog_one2one | 97.2637 | ENSG00000149927 | DOC2A | ortholog_one2one | 93.5323 | NA | NA | NA | NA | NA | NA | 13446 | 13446 | 8448 | 8448 |
| ENSMOCG00000022488 | 15.096635 | -0.6921829 | 0.2130034 | 0.0000065 | 0.0000937 | 101990319 | Gpr139 | protein_coding | 101990319 | Gpr139 | ENSMUSG00000066197 | Gpr139 | ortholog_one2one | 98.2609 | ENSG00000180269 | GPR139 | ortholog_one2one | 95.9420 | NA | NA | NA | NA | NA | NA | 209776 | 209776 | 124274 | 124274 |
| ENSMOCG00000007539 | 88.438606 | -0.3538033 | 0.1035529 | 0.0000065 | 0.0000937 | 101982323 | F8a | protein_coding | 101982323 | F8a | ENSMUSG00000078317 | F8a | ortholog_one2one | 91.5119 | ENSG00000277150 | F8A3 | ortholog_one2many | 83.5544 | ENSMUSG00000078317, ENSMUSG00000078317, ENSMUSG00000078317 | F8a, F8a, F8a | 91.5119, 91.5119, 91.5119 | ENSG00000277150, ENSG00000288709, ENSG00000288722 | F8A3, F8A2, F8A1 | 83.5544, 83.5544, 83.5544 | 14070 | 14070 | 474384 | 474384 |
| ENSMOCG00000014489 | 461.495717 | -0.2641765 | 0.0705071 | 0.0000068 | 0.0000978 | 101990266 | Mdga1 | protein_coding | 101990266 | Mdga1 | ENSMUSG00000043557 | Mdga1 | ortholog_one2one | 97.3822 | ENSG00000112139 | MDGA1 | ortholog_one2one | 96.2304 | NA | NA | NA | NA | NA | NA | 74762 | 74762 | 266727 | 266727 |
| ENSMOCG00000010284 | 2264.915501 | -0.4525974 | 0.1412401 | 0.0000070 | 0.0000997 | 101991040 | Slc6a11 | protein_coding | 101991040 | Slc6a11 | ENSMUSG00000030307 | Slc6a11 | ortholog_one2one | 99.2038 | ENSG00000132164 | SLC6A11 | ortholog_one2one | 95.3822 | NA | NA | NA | NA | NA | NA | 243616 | 243616 | 6538 | 6538 |
| ENSMOCG00000007158 | 152.483896 | -0.2927059 | 0.0807599 | 0.0000071 | 0.0001018 | 101993885 | Dtx4 | protein_coding | 101993885 | Dtx4 | ENSMUSG00000039982 | Dtx4 | ortholog_one2one | 94.8304 | ENSG00000110042 | DTX4 | ortholog_one2one | 92.7302 | NA | NA | NA | NA | NA | NA | 207521 | 207521 | 23220 | 23220 |
| ENSMOCG00000000815 | 25.429298 | -0.6092085 | 0.1904538 | 0.0000072 | 0.0001028 | 101995575 | Gbx2 | protein_coding | 101995575 | Gbx2 | ENSMUSG00000034486 | Gbx2 | ortholog_one2one | 99.4253 | ENSG00000168505 | GBX2 | ortholog_one2one | 97.7011 | NA | NA | NA | NA | NA | NA | 14472 | 14472 | 2637 | 2637 |
| ENSMOCG00000014573 | 19.564617 | -1.1089302 | 0.4166413 | 0.0000074 | 0.0001047 | 102001522 | Scrg1 | protein_coding | 102001522 | Scrg1 | ENSMUSG00000031610 | Scrg1 | ortholog_one2one | 87.7551 | ENSG00000164106 | SCRG1 | ortholog_one2one | 81.6327 | NA | NA | NA | NA | NA | NA | 20284 | 20284 | 11341 | 11341 |
| ENSMOCG00000003962 | 76.435392 | 0.9628330 | 0.3299766 | 0.0000074 | 0.0001048 | NA | Capn9 | protein_coding | NA | Capn9 | ENSMUSG00000031981 | Capn9 | ortholog_one2one | 88.6686 | ENSG00000135773 | CAPN9 | ortholog_one2one | 82.1530 | NA | NA | NA | NA | NA | NA | 73647 | 73647 | 10753 | 10753 |
| ENSMOCG00000019598 | 106.569032 | -0.6374623 | 0.1996243 | 0.0000075 | 0.0001059 | 101988970 | Aqp9 | protein_coding | 101988970 | Aqp9 | ENSMUSG00000032204 | Aqp9 | ortholog_one2one | 74.2373 | ENSG00000103569 | AQP9 | ortholog_one2one | 74.2373 | NA | NA | NA | NA | NA | NA | 64008 | 64008 | 366 | 366 |
| ENSMOCG00000001567 | 338.763583 | -0.2773824 | 0.0757000 | 0.0000077 | 0.0001083 | 101996556 | Ednrb | protein_coding | 101996556 | Ednrb | ENSMUSG00000022122 | Ednrb | ortholog_one2one | 90.0452 | ENSG00000136160 | EDNRB | ortholog_one2one | 85.2941 | NA | NA | NA | NA | NA | NA | 13618 | 13618 | 1910 | 1910 |
| ENSMOCG00000001521 | 30.782734 | -0.6368362 | 0.2003811 | 0.0000078 | 0.0001098 | 101990328 | Cdkn1c | protein_coding | 101990328 | Cdkn1c | ENSMUSG00000037664 | Cdkn1c | ortholog_one2one | 86.3636 | ENSG00000129757 | CDKN1C | ortholog_one2one | 49.7159 | NA | NA | NA | NA | NA | NA | 12577 | 12577 | 1028 | 1028 |
| ENSMOCG00000005186 | 42.898369 | -0.4102851 | 0.1274834 | 0.0000079 | 0.0001110 | 102000106 | 2410004P03Rik | protein_coding | 102000106 | 2410004P03Rik | ENSMUSG00000071398 | 2410004P03Rik | ortholog_one2one | 60.3015 | NA | NA | NA | NA | NA | NA | NA | 73667 | 73667 | NA | NA | |||
| ENSMOCG00000009356 | 68.415543 | -0.4179255 | 0.1304563 | 0.0000080 | 0.0001118 | NA | misc_RNA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000000062 | 102.751277 | -0.5217224 | 0.1662507 | 0.0000082 | 0.0001135 | 101983799 | Rnase6 | protein_coding | 101983799 | Rnase6 | ENSMUSG00000021880 | Rnase6 | ortholog_one2one | 69.7368 | ENSG00000169413 | RNASE6 | ortholog_one2one | 63.8158 | NA | NA | NA | NA | NA | NA | 78416 | 78416 | 6039 | 6039 |
| ENSMOCG00000017990 | 18.085317 | -0.7315653 | 0.2320364 | 0.0000082 | 0.0001141 | NA | protein_coding | NA | ENSMUSG00000020399 | Havcr2 | ortholog_one2one | 65.4088 | ENSG00000135077 | HAVCR2 | ortholog_one2one | 61.0063 | NA | NA | NA | NA | NA | NA | 171285 | 171285 | 84868 | 84868 | ||
| ENSMOCG00000012960 | 46.194695 | -0.5996416 | 0.1903212 | 0.0000083 | 0.0001148 | NA | Styxl1 | protein_coding | NA | Styxl1 | ENSMUSG00000019178 | Styxl1 | ortholog_one2one | 82.5000 | ENSG00000127952 | STYXL1 | ortholog_one2one | 65.3571 | NA | NA | NA | NA | NA | NA | 76571 | 76571 | 51657 | 51657 |
| ENSMOCG00000019693 | 97.188549 | 0.2785115 | 0.0766842 | 0.0000085 | 0.0001175 | 101999550 | Tgfa | protein_coding | 101999550 | Tgfa | ENSMUSG00000029999 | Tgfa | ortholog_one2one | 94.3396 | ENSG00000163235 | TGFA | ortholog_one2one | 92.4528 | NA | NA | NA | NA | NA | NA | 21802 | 21802 | 7039 | 7039 |
| ENSMOCG00000011785 | 264.979205 | -0.5733071 | 0.1831670 | 0.0000086 | 0.0001192 | 101984512 | Ccdc80 | protein_coding | 101984512 | Ccdc80 | ENSMUSG00000022665 | Ccdc80 | ortholog_one2one | 89.6515 | ENSG00000091986 | CCDC80 | ortholog_one2one | 84.6885 | NA | NA | NA | NA | NA | NA | 67896 | 67896 | 151887 | 151887 |
| ENSMOCG00000006173 | 62.506972 | 0.4089196 | 0.1280308 | 0.0000087 | 0.0001203 | 101992617 | Rigi | protein_coding | 101992617 | Rigi | ENSMUSG00000040296 | Rigi | ortholog_one2one | 86.2694 | ENSG00000107201 | RIGI | ortholog_one2one | 78.4974 | NA | NA | NA | NA | NA | NA | 230073 | 230073 | 23586 | 23586 |
| ENSMOCG00000013549 | 27.933192 | -0.5924250 | 0.1895331 | 0.0000089 | 0.0001221 | 101997405 | Rrad | protein_coding | 101997405 | Rrad | ENSMUSG00000031880 | Rrad | ortholog_one2one | 97.3771 | ENSG00000166592 | RRAD | ortholog_one2one | 91.1475 | NA | NA | NA | NA | NA | NA | 56437 | 56437 | 6236 | 6236 |
| ENSMOCG00000002881 | 65.125126 | -0.4497321 | 0.1434920 | 0.0000090 | 0.0001231 | 101986609 | Ankrd9 | protein_coding | 101986609 | Ankrd9 | ENSMUSG00000037904 | Ankrd9 | ortholog_one2one | 85.8790 | ENSG00000156381 | ANKRD9 | ortholog_one2one | 80.1153 | NA | NA | NA | NA | NA | NA | 74251 | 74251 | 122416 | 122416 |
| ENSMOCG00000012687 | 846.540902 | -0.2824391 | 0.0787420 | 0.0000094 | 0.0001283 | 101982904 | Sst | protein_coding | 101982904 | Sst | ENSMUSG00000004366 | Sst | ortholog_one2one | 99.1379 | ENSG00000157005 | SST | ortholog_one2one | 97.4138 | NA | NA | NA | NA | NA | NA | 20604 | 20604 | 6750 | 6750 |
| ENSMOCG00000010202 | 13.178081 | 0.7890213 | 0.2581464 | 0.0000094 | 0.0001286 | 101999580 | F13b | protein_coding | 101999580 | F13b | ENSMUSG00000026368 | F13b | ortholog_one2one | 86.4992 | ENSG00000143278 | F13B | ortholog_one2one | 78.0220 | NA | NA | NA | NA | NA | NA | 14060 | 14060 | 2165 | 2165 |
| ENSMOCG00000022463 | 68.877307 | -0.3072177 | 0.0882761 | 0.0000096 | 0.0001299 | 101983772 | Tmem163 | protein_coding | 101983772 | Tmem163 | ENSMUSG00000026347 | Tmem163 | ortholog_one2one | 97.5694 | ENSG00000152128 | TMEM163 | ortholog_one2one | 91.6667 | NA | NA | NA | NA | NA | NA | 72160 | 72160 | 81615 | 81615 |
| ENSMOCG00000015274 | 120.479460 | -0.4369937 | 0.1401656 | 0.0000099 | 0.0001331 | 101979552 | Pmp22 | protein_coding | 101979552 | Pmp22 | ENSMUSG00000018217 | Pmp22 | ortholog_one2one | 91.2500 | ENSG00000109099 | PMP22 | ortholog_one2one | 83.7500 | NA | NA | NA | NA | NA | NA | 18858 | 18858 | 5376 | 5376 |
| ENSMOCG00000018409 | 25.491657 | 0.7559895 | 0.2467192 | 0.0000099 | 0.0001331 | 101980456 | Otogl | protein_coding | 101980456 | Otogl | ENSMUSG00000091455 | Otogl | ortholog_one2one | 92.0928 | ENSG00000165899 | OTOGL | ortholog_one2one | 87.6236 | NA | NA | NA | NA | NA | NA | 628870 | 628870 | 283310 | 283310 |
| ENSMOCG00000021320 | 50.240116 | -0.3887429 | 0.1217017 | 0.0000100 | 0.0001345 | 101991603 | Bmper | protein_coding | 101991603 | Bmper | ENSMUSG00000031963 | Bmper | ortholog_one2one | 95.7664 | ENSG00000164619 | BMPER | ortholog_one2one | 92.7007 | NA | NA | NA | NA | NA | NA | 73230 | 73230 | 168667 | 168667 |
| ENSMOCG00000003843 | 445.081631 | 0.2554074 | 0.0697980 | 0.0000104 | 0.0001393 | 101995925 | Grin2a | protein_coding | 101995925 | Grin2a | ENSMUSG00000059003 | Grin2a | ortholog_one2one | 98.0874 | ENSG00000183454 | GRIN2A | ortholog_one2one | 94.6038 | NA | NA | NA | NA | NA | NA | 14811 | 14811 | 2903 | 2903 |
| ENSMOCG00000004252 | 158.580681 | -0.2637647 | 0.0727598 | 0.0000106 | 0.0001413 | 101989612 | Fbxl14 | protein_coding | 101989612 | Fbxl14 | ENSMUSG00000030019 | Fbxl14 | ortholog_one2one | 100.0000 | ENSG00000171823 | FBXL14 | ortholog_one2one | 99.7500 | NA | NA | NA | NA | NA | NA | 101358 | 101358 | 144699 | 144699 |
| ENSMOCG00000013403 | 51.952247 | -0.6416193 | 0.2097818 | 0.0000110 | 0.0001465 | 102001167 | Myo15b | protein_coding | 102001167 | Myo15b | ENSMUSG00000034427 | Myo15b | ortholog_one2one | 79.9266 | ENSG00000266714 | MYO15B | ortholog_one2one | 67.0223 | NA | NA | NA | NA | NA | NA | 217328 | 217328 | 80022 | 80022 |
| ENSMOCG00000008164 | 113.574521 | -0.2978102 | 0.0857357 | 0.0000112 | 0.0001489 | 101995674 | Ckap4 | protein_coding | 101995674 | Ckap4 | ENSMUSG00000046841 | Ckap4 | ortholog_one2one | 83.7563 | ENSG00000136026 | CKAP4 | ortholog_one2one | 78.0034 | NA | NA | NA | NA | NA | NA | 216197 | 216197 | 10970 | 10970 |
| ENSMOCG00000007684 | 52.137220 | -0.7969581 | 0.2679699 | 0.0000112 | 0.0001491 | 101985115 | Dnah1 | protein_coding | 101985115 | Dnah1 | ENSMUSG00000019027 | Dnah1 | ortholog_one2one | 88.9218 | ENSG00000114841 | DNAH1 | ortholog_one2one | 85.5482 | NA | NA | NA | NA | NA | NA | 110084 | 110084 | 25981 | 25981 |
| ENSMOCG00000008162 | 59.575843 | -0.4538842 | 0.1483530 | 0.0000114 | 0.0001512 | 101980967 | Tmem254 | protein_coding | 101980967 | Tmem254 | ENSMUSG00000072676 | Tmem254 | ortholog_one2one | 84.4961 | ENSG00000133678 | TMEM254 | ortholog_one2one | 65.1163 | NA | NA | NA | NA | NA | NA | 66039 | 66039 | 80195 | 80195 |
| ENSMOCG00000000906 | 124.476022 | -0.3414070 | 0.1036608 | 0.0000115 | 0.0001519 | 101980503 | Brinp3 | protein_coding | 101980503 | Brinp3 | ENSMUSG00000035131 | Brinp3 | ortholog_one2one | 98.4334 | ENSG00000162670 | BRINP3 | ortholog_one2one | 96.6057 | NA | NA | NA | NA | NA | NA | 215378 | 215378 | 339479 | 339479 |
| ENSMOCG00000000254 | 178.300913 | -0.3879569 | 0.1236294 | 0.0000122 | 0.0001608 | 101999544 | Asb4 | protein_coding | 101999544 | Asb4 | ENSMUSG00000042607 | Asb4 | ortholog_one2one | 91.6279 | ENSG00000005981 | ASB4 | ortholog_one2one | 88.8372 | NA | NA | NA | NA | NA | NA | 65255 | 65255 | 51666 | 51666 |
| ENSMOCG00000018320 | 62.753381 | -0.6934091 | 0.2305786 | 0.0000124 | 0.0001622 | 102001477 | Sema3c | protein_coding | 102001477 | Sema3c | ENSMUSG00000028780 | Sema3c | ortholog_one2one | 97.4734 | ENSG00000075223 | SEMA3C | ortholog_one2one | 96.1436 | NA | NA | NA | NA | NA | NA | 20348 | 20348 | 10512 | 10512 |
| ENSMOCG00000021530 | 26.231833 | -0.7643338 | 0.2581218 | 0.0000125 | 0.0001633 | 101997814 | Zmynd10 | protein_coding | 101997814 | Zmynd10 | ENSMUSG00000010044 | Zmynd10 | ortholog_one2one | 92.0455 | ENSG00000004838 | ZMYND10 | ortholog_one2one | 88.8636 | NA | NA | NA | NA | NA | NA | 114602 | 114602 | 51364 | 51364 |
| ENSMOCG00000006805 | 57.208562 | -0.3749878 | 0.1188974 | 0.0000129 | 0.0001678 | NA | protein_coding | NA | ENSMUSG00000058056 | Palld | ortholog_one2one | 96.0784 | ENSG00000129116 | PALLD | ortholog_one2one | 64.2534 | NA | NA | NA | NA | NA | NA | 72333 | 72333 | 23022 | 23022 | ||
| ENSMOCG00000020379 | 61.287284 | -0.6184622 | 0.2069722 | 0.0000134 | 0.0001734 | NA | Ifitm10 | protein_coding | NA | Ifitm10 | ENSMUSG00000045777 | Ifitm10 | ortholog_one2one | 99.0050 | ENSG00000244242 | IFITM10 | ortholog_one2one | 94.0299 | NA | NA | NA | NA | NA | NA | 320802 | 320802 | 402778 | 402778 |
| ENSMOCG00000003881 | 465.211176 | -0.4188906 | 0.1372679 | 0.0000134 | 0.0001736 | 101981243 | Lhx6 | protein_coding | 101981243 | Lhx6 | ENSMUSG00000026890 | Lhx6 | ortholog_one2one | 98.7245 | ENSG00000106852 | LHX6 | ortholog_one2one | 98.7245 | NA | NA | NA | NA | NA | NA | 16874 | 16874 | 26468 | 26468 |
| ENSMOCG00000007120 | 158.584529 | -0.4125809 | 0.1347705 | 0.0000134 | 0.0001736 | 101992041 | Col6a2 | protein_coding | 101992041 | Col6a2 | ENSMUSG00000020241 | Col6a2 | ortholog_one2one | 97.2710 | ENSG00000142173 | COL6A2 | ortholog_one2one | 90.8382 | NA | NA | NA | NA | NA | NA | 12834 | 12834 | 1292 | 1292 |
| ENSMOCG00000015807 | 123.993966 | -0.3327583 | 0.1016582 | 0.0000137 | 0.0001761 | 101981679 | Hs3st1 | protein_coding | 101981679 | Hs3st1 | ENSMUSG00000051022 | Hs3st1 | ortholog_one2one | 94.8553 | ENSG00000002587 | HS3ST1 | ortholog_one2one | 88.1029 | NA | NA | NA | NA | NA | NA | 15476 | 15476 | 9957 | 9957 |
| ENSMOCG00000009346 | 28.188188 | -0.5287575 | 0.1777924 | 0.0000138 | 0.0001773 | 101993248 | Adamts19 | protein_coding | 101993248 | Adamts19 | ENSMUSG00000053441 | Adamts19 | ortholog_one2one | 90.7346 | ENSG00000145808 | ADAMTS19 | ortholog_one2one | 86.7279 | NA | NA | NA | NA | NA | NA | 240322 | 240322 | 171019 | 171019 |
| ENSMOCG00000015137 | 110.149229 | 0.3015705 | 0.0888909 | 0.0000140 | 0.0001791 | 101990341 | Xrcc4 | protein_coding | 101990341 | Xrcc4 | ENSMUSG00000021615 | Xrcc4 | ortholog_one2one | 81.5951 | ENSG00000152422 | XRCC4 | ortholog_one2one | 78.2209 | NA | NA | NA | NA | NA | NA | 108138 | 108138 | 7518 | 7518 |
| ENSMOCG00000011236 | 13.971525 | -0.6879890 | 0.2323449 | 0.0000140 | 0.0001792 | 101990940 | protein_coding | 101990940 | ENSMUSG00000029552 | Tes | ortholog_one2many | 93.3014 | ENSG00000135269 | TES | ortholog_one2one | 91.1483 | ENSMUSG00000029552, ENSMUSG00000068113 | Tes, Tesl1 | 93.3014, 80.3828 | ENSG00000135269, ENSG00000135269 | TES, TES | 91.1483, 91.1483 | 21753 | 21753 | 26136 | 26136 | ||
| ENSMOCG00000010139 | 9.518037 | -1.2173321 | 0.5696638 | 0.0000141 | 0.0001799 | NA | Gbx1 | protein_coding | NA | Gbx1 | ENSMUSG00000067724 | Gbx1 | ortholog_one2one | 87.8571 | ENSG00000164900 | GBX1 | ortholog_one2one | 77.1429 | NA | NA | NA | NA | NA | NA | 231044 | 231044 | 2636 | 2636 |
| ENSMOCG00000005266 | 105.871984 | 0.4160573 | 0.1371870 | 0.0000145 | 0.0001850 | 101994465 | Hhatl | protein_coding | 101994465 | Hhatl | ENSMUSG00000032523 | Hhatl | ortholog_one2one | 95.2381 | ENSG00000010282 | HHATL | ortholog_one2one | 91.2698 | NA | NA | NA | NA | NA | NA | 74770 | 74770 | 57467 | 57467 |
| ENSMOCG00000021567 | 104.119420 | 0.3001516 | 0.0888145 | 0.0000149 | 0.0001896 | 101992315 | Arl15 | protein_coding | 101992315 | Arl15 | ENSMUSG00000042348 | Arl15 | ortholog_one2one | 95.5882 | ENSG00000185305 | ARL15 | ortholog_one2one | 96.5686 | NA | NA | NA | NA | NA | NA | 218639 | 218639 | 54622 | 54622 |
| ENSMOCG00000006409 | 205.994791 | 0.3615019 | 0.1150328 | 0.0000152 | 0.0001938 | 101981870 | St6gal1 | protein_coding | 101981870 | St6gal1 | ENSMUSG00000022885 | St6gal1 | ortholog_one2one | 79.9499 | ENSG00000073849 | ST6GAL1 | ortholog_one2one | 81.2030 | NA | NA | NA | NA | NA | NA | 20440 | 20440 | 6480 | 6480 |
| ENSMOCG00000017657 | 43.996240 | -0.4801475 | 0.1627468 | 0.0000155 | 0.0001966 | 101993005 | Acrbp | protein_coding | 101993005 | Acrbp | ENSMUSG00000072770 | Acrbp | ortholog_one2one | 85.2126 | ENSG00000111644 | ACRBP | ortholog_one2one | 74.1220 | NA | NA | NA | NA | NA | NA | 54137 | 54137 | 84519 | 84519 |
| ENSMOCG00000006100 | 141.254587 | -0.6996432 | 0.2409974 | 0.0000159 | 0.0002015 | 102002433 | Kcnc4 | protein_coding | 102002433 | Kcnc4 | ENSMUSG00000027895 | Kcnc4 | ortholog_one2one | 92.6040 | ENSG00000116396 | KCNC4 | ortholog_one2one | 91.5254 | NA | NA | NA | NA | NA | NA | 99738 | 99738 | 3749 | 3749 |
| ENSMOCG00000018159 | 365.735730 | -0.2643973 | 0.0757003 | 0.0000166 | 0.0002092 | 101982576 | Cygb | protein_coding | 101982576 | Cygb | ENSMUSG00000020810 | Cygb | ortholog_one2one | 97.3684 | ENSG00000161544 | CYGB | ortholog_one2one | 94.7368 | NA | NA | NA | NA | NA | NA | 114886 | 114886 | 114757 | 114757 |
| ENSMOCG00000008829 | 109.950450 | -0.4908988 | 0.1681103 | 0.0000168 | 0.0002104 | 101993762 | Sumf2 | protein_coding | 101993762 | Sumf2 | ENSMUSG00000025538 | Sumf2 | ortholog_one2one | 87.0130 | ENSG00000129103 | SUMF2 | ortholog_one2one | 77.9221 | NA | NA | NA | NA | NA | NA | 67902 | 67902 | 25870 | 25870 |
| ENSMOCG00000002526 | 118.200977 | -0.2793258 | 0.0814152 | 0.0000168 | 0.0002104 | 101996935 | Tprn | protein_coding | 101996935 | Tprn | ENSMUSG00000048707 | Tprn | ortholog_one2one | 84.1823 | ENSG00000176058 | TPRN | ortholog_one2one | 65.5496 | NA | NA | NA | NA | NA | NA | 97031 | 97031 | 286262 | 286262 |
| ENSMOCG00000019653 | 109.764631 | -0.4510088 | 0.1531042 | 0.0000167 | 0.0002104 | 101981686 | Grin2d | protein_coding | 101981686 | Grin2d | ENSMUSG00000002771 | Grin2d | ortholog_one2one | 98.1147 | ENSG00000105464 | GRIN2D | ortholog_one2one | 96.7793 | NA | NA | NA | NA | NA | NA | 14814 | 14814 | 2906 | 2906 |
| ENSMOCG00000018599 | 1823.308430 | -0.2612780 | 0.0746268 | 0.0000168 | 0.0002108 | NA | Hap1 | protein_coding | NA | Hap1 | ENSMUSG00000006930 | Hap1 | ortholog_one2one | 80.7210 | ENSG00000173805 | HAP1 | ortholog_one2one | 55.6426 | NA | NA | NA | NA | NA | NA | 15114 | 15114 | 9001 | 9001 |
| ENSMOCG00000002718 | 69.515418 | -0.3035706 | 0.0914256 | 0.0000172 | 0.0002155 | 102000821 | Arhgap24 | protein_coding | 102000821 | Arhgap24 | ENSMUSG00000057315 | Arhgap24 | ortholog_one2one | 91.5515 | ENSG00000138639 | ARHGAP24 | ortholog_one2one | 88.4793 | NA | NA | NA | NA | NA | NA | 231532 | 231532 | 83478 | 83478 |
| ENSMOCG00000000941 | 41.827568 | 0.3752083 | 0.1224490 | 0.0000173 | 0.0002164 | 102002593 | Samd12 | protein_coding | 102002593 | Samd12 | ENSMUSG00000058656 | Samd12 | ortholog_one2one | 93.1677 | ENSG00000177570 | SAMD12 | ortholog_one2one | 91.3043 | NA | NA | NA | NA | NA | NA | 320679 | 320679 | 401474 | 401474 |
| ENSMOCG00000016826 | 17.411044 | -1.2400783 | 0.6304920 | 0.0000176 | 0.0002190 | 102000388 | Irs4 | protein_coding | 102000388 | Irs4 | ENSMUSG00000054667 | Irs4 | ortholog_one2one | 79.9666 | ENSG00000133124 | IRS4 | ortholog_one2one | 75.7930 | NA | NA | NA | NA | NA | NA | 16370 | 16370 | 8471 | 8471 |
| ENSMOCG00000013997 | 145.157168 | 0.2703702 | 0.0783303 | 0.0000177 | 0.0002199 | NA | Trmt9b | protein_coding | NA | Trmt9b | ENSMUSG00000039620 | Trmt9b | ortholog_one2one | 84.0449 | ENSG00000250305 | TRMT9B | ortholog_one2one | 70.1124 | NA | NA | NA | NA | NA | NA | 319582 | 319582 | 57604 | 57604 |
| ENSMOCG00000015637 | 535.145949 | -0.2859139 | 0.0844441 | 0.0000178 | 0.0002210 | 101994450 | Ttc21b | protein_coding | 101994450 | Ttc21b | ENSMUSG00000034848 | Ttc21b | ortholog_one2one | 95.5133 | ENSG00000123607 | TTC21B | ortholog_one2one | 84.6388 | NA | NA | NA | NA | NA | NA | 73668 | 73668 | 79809 | 79809 |
| ENSMOCG00000001370 | 15.387758 | -2.0053191 | 1.4375439 | 0.0000179 | 0.0002228 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000003283 | 21.202625 | -0.6187859 | 0.2153005 | 0.0000183 | 0.0002267 | 101997025 | Htr1a | protein_coding | 101997025 | Htr1a | ENSMUSG00000021721 | Htr1a | ortholog_one2one | 93.8242 | ENSG00000178394 | HTR1A | ortholog_one2one | 90.0238 | NA | NA | NA | NA | NA | NA | 15550 | 15550 | 3350 | 3350 |
| ENSMOCG00000014029 | 259.715948 | 0.2911261 | 0.0868025 | 0.0000184 | 0.0002269 | 101982514 | Enpp1 | protein_coding | 101982514 | Enpp1 | ENSMUSG00000037370 | Enpp1 | ortholog_one2one | 85.7773 | ENSG00000197594 | ENPP1 | ortholog_one2one | 77.7288 | NA | NA | NA | NA | NA | NA | 18605 | 18605 | 5167 | 5167 |
| ENSMOCG00000006438 | 22.092633 | 0.5184046 | 0.1800920 | 0.0000186 | 0.0002292 | 101997595 | Plau | protein_coding | 101997595 | Plau | ENSMUSG00000021822 | Plau | ortholog_one2one | 80.4245 | ENSG00000122861 | PLAU | ortholog_one2one | 72.1698 | NA | NA | NA | NA | NA | NA | 18792 | 18792 | 5328 | 5328 |
| ENSMOCG00000015262 | 79.335833 | -0.4361738 | 0.1491403 | 0.0000189 | 0.0002316 | 101984908 | Ak8 | protein_coding | 101984908 | Ak8 | ENSMUSG00000026807 | Ak8 | ortholog_one2one | 88.3090 | ENSG00000165695 | AK8 | ortholog_one2one | 76.4092 | NA | NA | NA | NA | NA | NA | 68870 | 68870 | 158067 | 158067 |
| ENSMOCG00000003014 | 174.003957 | -0.2730655 | 0.0799772 | 0.0000193 | 0.0002364 | 101986330 | protein_coding | 101986330 | ENSMUSG00000032531 | Amotl2 | ortholog_one2one | 95.8904 | ENSG00000114019 | AMOTL2 | ortholog_one2one | 84.4749 | NA | NA | NA | NA | NA | NA | 56332 | 56332 | 51421 | 51421 | ||
| ENSMOCG00000018424 | 99.593890 | 0.3833909 | 0.1276577 | 0.0000198 | 0.0002410 | 101983848 | Adat1 | protein_coding | 101983848 | Adat1 | ENSMUSG00000031949 | Adat1 | ortholog_one2one | 86.7470 | ENSG00000065457 | ADAT1 | ortholog_one2one | 79.9197 | NA | NA | NA | NA | NA | NA | 30947 | 30947 | 23536 | 23536 |
| ENSMOCG00000005108 | 371.149809 | 0.2875061 | 0.0859273 | 0.0000198 | 0.0002414 | 101986252 | Kcnh4 | protein_coding | 101986252 | Kcnh4 | ENSMUSG00000035355 | Kcnh4 | ortholog_one2one | 94.9902 | ENSG00000089558 | KCNH4 | ortholog_one2one | 90.0786 | NA | NA | NA | NA | NA | NA | 380728 | 380728 | 23415 | 23415 |
| ENSMOCG00000018967 | 14.927662 | -0.8245198 | 0.3098967 | 0.0000202 | 0.0002450 | 101982817 | pseudogene | 101982817 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000001477 | 101.338444 | -0.2503186 | 0.0717977 | 0.0000203 | 0.0002453 | 101981499 | Sh2b2 | protein_coding | 101981499 | Sh2b2 | ENSMUSG00000005057 | Sh2b2 | ortholog_one2one | 94.5250 | ENSG00000160999 | SH2B2 | ortholog_one2one | 85.1852 | NA | NA | NA | NA | NA | NA | 23921 | 23921 | 10603 | 10603 |
| ENSMOCG00000010478 | 2625.028548 | 0.2537097 | 0.0731622 | 0.0000207 | 0.0002497 | 101995101 | Cttnbp2 | protein_coding | 101995101 | Cttnbp2 | ENSMUSG00000000416 | Cttnbp2 | ortholog_one2one | 91.4338 | ENSG00000077063 | CTTNBP2 | ortholog_one2one | 85.9052 | NA | NA | NA | NA | NA | NA | 30785 | 30785 | 83992 | 83992 |
| ENSMOCG00000020696 | 97.401380 | 0.3414347 | 0.1098152 | 0.0000210 | 0.0002531 | 101999167 | Ndst3 | protein_coding | 101999167 | Ndst3 | ENSMUSG00000027977 | Ndst3 | ortholog_one2one | 96.9072 | ENSG00000164100 | NDST3 | ortholog_one2one | 93.3562 | NA | NA | NA | NA | NA | NA | 83398 | 83398 | 9348 | 9348 |
| ENSMOCG00000019765 | 121.647760 | -0.3170975 | 0.0990154 | 0.0000211 | 0.0002531 | 101983718 | Fam181b | protein_coding | 101983718 | Fam181b | ENSMUSG00000051515 | Fam181b | ortholog_one2one | 87.6190 | ENSG00000182103 | FAM181B | ortholog_one2one | 79.7619 | NA | NA | NA | NA | NA | NA | 58238 | 58238 | 220382 | 220382 |
| ENSMOCG00000017803 | 1161.301734 | 0.2518025 | 0.0725738 | 0.0000211 | 0.0002531 | 101989555 | protein_coding | 101989555 | ENSMUSG00000042032 | Mat2b | ortholog_one2one | 98.0831 | ENSG00000038274 | MAT2B | ortholog_one2one | 95.2077 | NA | NA | NA | NA | NA | NA | 108645 | 108645 | 27430 | 27430 | ||
| ENSMOCG00000017266 | 42.638590 | 0.6957132 | 0.2499423 | 0.0000214 | 0.0002561 | 101997900 | Krt24 | protein_coding | 101997900 | Krt24 | ENSMUSG00000020913 | Krt24 | ortholog_one2one | 79.0698 | ENSG00000167916 | KRT24 | ortholog_one2one | 70.7364 | NA | NA | NA | NA | NA | NA | 75706 | 75706 | 192666 | 192666 |
| ENSMOCG00000020098 | 16.217892 | -0.7988738 | 0.2997020 | 0.0000217 | 0.0002588 | NA | protein_coding | NA | ENSMUSG00000028334 | Nans | ortholog_one2many | 90.8587 | ENSG00000095380 | NANS | ortholog_one2many | 91.1357 | NA | NA | NA | NA | NA | NA | 94181 | 94181 | 54187 | 54187 | ||
| ENSMOCG00000019374 | 120.294186 | 0.2878730 | 0.0868104 | 0.0000217 | 0.0002589 | 101996689 | Slx1b | protein_coding | 101996689 | Slx1b | ENSMUSG00000059772 | Slx1b | ortholog_one2one | 90.7407 | ENSG00000132207 | SLX1A | ortholog_one2many | 73.7037 | ENSMUSG00000059772, ENSMUSG00000059772 | Slx1b, Slx1b | 90.7407, 90.7407 | ENSG00000132207, ENSG00000181625 | SLX1A, SLX1B | 73.7037, 73.7037 | 75764 | 75764 | 548593, 124907837 | 548593 |
| ENSMOCG00000021698 | 322.056586 | -0.3528483 | 0.1152916 | 0.0000217 | 0.0002589 | 101981900 | Snap47 | protein_coding | 101981900 | Snap47 | ENSMUSG00000009894 | Snap47 | ortholog_one2one | 80.1435 | ENSG00000143740 | SNAP47 | ortholog_one2one | 73.6842 | NA | NA | NA | NA | NA | NA | 67826 | 67826 | 116841 | 116841 |
| ENSMOCG00000002700 | 62.519618 | 0.8438459 | 0.3268108 | 0.0000220 | 0.0002611 | NA | Hcar2 | protein_coding | NA | Hcar2 | ENSMUSG00000045502 | Hcar2 | ortholog_one2one | 89.2265 | ENSG00000182782 | HCAR2 | ortholog_one2many | 82.0442 | ENSMUSG00000045502, ENSMUSG00000045502 | Hcar2, Hcar2 | 89.2265, 89.2265 | ENSG00000182782, ENSG00000255398 | HCAR2, HCAR3 | 82.0442, 79.0055 | 80885 | 80885 | 338442 | 338442 |
| ENSMOCG00000005304 | 382.409995 | -0.3656226 | 0.1211957 | 0.0000220 | 0.0002611 | 102001800 | Nectin1 | protein_coding | 102001800 | Nectin1 | ENSMUSG00000032012 | Nectin1 | ortholog_one2one | 97.4708 | ENSG00000110400 | NECTIN1 | ortholog_one2one | 94.7471 | NA | NA | NA | NA | NA | NA | 58235 | 58235 | 5818 | 5818 |
| ENSMOCG00000010773 | 64.770772 | 0.6812661 | 0.2451045 | 0.0000221 | 0.0002614 | 101994983 | processed_pseudogene | 101994983 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000012400 | 198.918121 | 0.2581603 | 0.0752462 | 0.0000222 | 0.0002625 | 101997063 | Mtap | protein_coding | 101997063 | Mtap | ENSMUSG00000062937 | Mtap | ortholog_one2one | 96.4664 | ENSG00000099810 | MTAP | ortholog_one2one | 92.9329 | NA | NA | NA | NA | NA | NA | 66902 | 66902 | 4507 | 4507 |
| ENSMOCG00000000888 | 635.110194 | -0.3188108 | 0.1004950 | 0.0000227 | 0.0002676 | 102002672 | Parm1 | protein_coding | 102002672 | Parm1 | ENSMUSG00000034981 | Parm1 | ortholog_one2one | 72.7575 | ENSG00000169116 | PARM1 | ortholog_one2one | 62.1262 | NA | NA | NA | NA | NA | NA | 231440 | 231440 | 25849 | 25849 |
| ENSMOCG00000013174 | 29.646333 | -0.8037691 | 0.3059328 | 0.0000230 | 0.0002714 | 101998998 | Pon3 | protein_coding | 101998998 | Pon3 | ENSMUSG00000029759 | Pon3 | ortholog_one2one | 87.2881 | ENSG00000105852 | PON3 | ortholog_one2one | 80.7910 | NA | NA | NA | NA | NA | NA | 269823 | 269823 | 5446 | 5446 |
| ENSMOCG00000013728 | 91.076664 | -0.2670331 | 0.0793296 | 0.0000245 | 0.0002845 | 101988812 | Syngr2 | protein_coding | 101988812 | Syngr2 | ENSMUSG00000048277 | Syngr2 | ortholog_one2one | 92.8571 | ENSG00000108639 | SYNGR2 | ortholog_one2one | 86.1607 | NA | NA | NA | NA | NA | NA | 20973 | 20973 | 9144 | 9144 |
| ENSMOCG00000011532 | 79.913050 | -0.2954185 | 0.0915884 | 0.0000262 | 0.0003026 | 102000226 | Crhr1 | protein_coding | 102000226 | Crhr1 | ENSMUSG00000018634 | Crhr1 | ortholog_one2one | 97.5904 | ENSG00000120088 | CRHR1 | ortholog_one2one | 97.5904 | NA | NA | NA | NA | NA | NA | 12921 | 12921 | 1394, 104909134 | 1394 |
| ENSMOCG00000003934 | 37.781040 | -0.4528719 | 0.1619060 | 0.0000267 | 0.0003076 | 101984051 | Cbln1 | protein_coding | 101984051 | Cbln1 | ENSMUSG00000031654 | Cbln1 | ortholog_one2one | 99.4819 | ENSG00000102924 | CBLN1 | ortholog_one2one | 99.4819 | NA | NA | NA | NA | NA | NA | 12404 | 12404 | 869 | 869 |
| ENSMOCG00000002870 | 64.118463 | -0.4009309 | 0.1397218 | 0.0000268 | 0.0003085 | 101988848 | Zcchc3 | protein_coding | 101988848 | Zcchc3 | ENSMUSG00000074682 | Zcchc3 | ortholog_one2one | 93.1990 | ENSG00000247315 | ZCCHC3 | ortholog_one2one | 87.9093 | NA | NA | NA | NA | NA | NA | 67917 | 67917 | 85364 | 85364 |
| ENSMOCG00000017850 | 20.368635 | -0.5254503 | 0.1908291 | 0.0000269 | 0.0003094 | NA | Mettl21c | protein_coding | NA | Mettl21c | ENSMUSG00000047343 | Mettl21c | ortholog_one2one | 82.0833 | ENSG00000139780 | METTL21C | ortholog_one2one | 80.8333 | NA | NA | NA | NA | NA | NA | 433294 | 433294 | 196541 | 196541 |
| ENSMOCG00000007327 | 211.836636 | 0.4190622 | 0.1479057 | 0.0000272 | 0.0003120 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000018737 | 162.913422 | 0.3230073 | 0.1048764 | 0.0000288 | 0.0003278 | NA | protein_coding | NA | ENSMUSG00000020380 | Rad50 | ortholog_one2one | 97.6562 | ENSG00000113522 | RAD50 | ortholog_one2one | 95.3125 | NA | NA | NA | NA | NA | NA | 19360 | 19360 | 10111 | 10111 | ||
| ENSMOCG00000016518 | 117.411161 | -0.2991984 | 0.0943363 | 0.0000295 | 0.0003345 | 101982803 | Tspan15 | protein_coding | 101982803 | Tspan15 | ENSMUSG00000037031 | Tspan15 | ortholog_one2one | 96.2585 | ENSG00000099282 | TSPAN15 | ortholog_one2one | 92.5170 | NA | NA | NA | NA | NA | NA | 70423 | 70423 | 23555 | 23555 |
| ENSMOCG00000000089 | 17.827766 | -0.6607420 | 0.2480752 | 0.0000301 | 0.0003405 | 101983592 | Odad4 | protein_coding | 101983592 | Odad4 | ENSMUSG00000006784 | Odad4 | ortholog_one2one | 87.2581 | ENSG00000204815 | ODAD4 | ortholog_one2one | 82.2581 | NA | NA | NA | NA | NA | NA | 74407 | 74407 | 83538 | 83538 |
| ENSMOCG00000014230 | 43.957102 | -0.3554986 | 0.1206172 | 0.0000302 | 0.0003414 | 101991682 | Cep128 | protein_coding | 101991682 | Cep128 | ENSMUSG00000061533 | Cep128 | ortholog_one2one | 80.1603 | ENSG00000100629 | CEP128 | ortholog_one2one | 80.8617 | NA | NA | NA | NA | NA | NA | 75216 | 75216 | 145508 | 145508 |
| ENSMOCG00000015293 | 33.332435 | -0.4536870 | 0.1645893 | 0.0000302 | 0.0003415 | 102000580 | Pou2f3 | protein_coding | 102000580 | Pou2f3 | ENSMUSG00000032015 | Pou2f3 | ortholog_one2one | 96.5035 | ENSG00000137709 | POU2F3 | ortholog_one2one | 93.2401 | NA | NA | NA | NA | NA | NA | 18988 | 18988 | 25833 | 25833 |
| ENSMOCG00000017799 | 111.497343 | 0.3933771 | 0.1386514 | 0.0000311 | 0.0003506 | 101992193 | protein_coding | 101992193 | NA | ENSG00000159917 | ZNF235 | ortholog_one2one | 77.2006 | NA | NA | NA | NA | NA | NA | NA | NA | 9310 | 9310 | |||||
| ENSMOCG00000000221 | 118.719028 | -0.2771857 | 0.0856549 | 0.0000325 | 0.0003635 | 101983345 | Plxdc2 | protein_coding | 101983345 | Plxdc2 | ENSMUSG00000026748 | Plxdc2 | ortholog_one2one | 93.7736 | ENSG00000120594 | PLXDC2 | ortholog_one2one | 92.0755 | NA | NA | NA | NA | NA | NA | 67448 | 67448 | 84898 | 84898 |
| ENSMOCG00000018602 | 17.892139 | -0.7115387 | 0.2754479 | 0.0000326 | 0.0003647 | NA | Nsun4 | protein_coding | NA | Nsun4 | ENSMUSG00000028706 | Nsun4 | ortholog_one2one | 65.8507 | NA | NA | NA | NA | NA | NA | NA | 72181 | 72181 | NA | NA | |||
| ENSMOCG00000020950 | 35.467211 | -0.4956641 | 0.1836107 | 0.0000327 | 0.0003651 | 101999802 | Afm | protein_coding | 101999802 | Afm | ENSMUSG00000029369 | Afm | ortholog_one2one | 75.2459 | ENSG00000079557 | AFM | ortholog_one2one | 62.9508 | NA | NA | NA | NA | NA | NA | 280662 | 280662 | 173 | 173 |
| ENSMOCG00000005042 | 136.759962 | -0.3633611 | 0.1258592 | 0.0000338 | 0.0003757 | 101991194 | Shd | protein_coding | 101991194 | Shd | ENSMUSG00000039154 | Shd | ortholog_one2one | 82.1212 | ENSG00000105251 | SHD | ortholog_one2one | 75.7576 | NA | NA | NA | NA | NA | NA | 20420 | 20420 | 56961 | 56961 |
| ENSMOCG00000018127 | 83.436000 | -0.3150735 | 0.1031483 | 0.0000344 | 0.0003812 | 101994422 | Dusp15 | protein_coding | 101994422 | Dusp15 | ENSMUSG00000042662 | Dusp15 | ortholog_one2one | 91.3793 | ENSG00000149599 | DUSP15 | ortholog_one2one | 90.9483 | NA | NA | NA | NA | NA | NA | 252864 | 252864 | 128853 | 128853 |
| ENSMOCG00000016476 | 109.811267 | -0.2639289 | 0.0807803 | 0.0000351 | 0.0003887 | 102002600 | Bmp7 | protein_coding | 102002600 | Bmp7 | ENSMUSG00000008999 | Bmp7 | ortholog_one2one | 99.3023 | ENSG00000101144 | BMP7 | ortholog_one2one | 97.6744 | NA | NA | NA | NA | NA | NA | 12162 | 12162 | 655 | 655 |
| ENSMOCG00000014319 | 254.444087 | -0.3260737 | 0.1086816 | 0.0000354 | 0.0003909 | 101989204 | Glra2 | protein_coding | 101989204 | Glra2 | ENSMUSG00000018589 | Glra2 | ortholog_one2one | 96.2472 | ENSG00000101958 | GLRA2 | ortholog_one2one | 95.8057 | NA | NA | NA | NA | NA | NA | 237213 | 237213 | 2742 | 2742 |
| ENSMOCG00000014248 | 195.261726 | 0.2664921 | 0.0819596 | 0.0000357 | 0.0003935 | 102000770 | Zfp488 | protein_coding | 102000770 | Zfp488 | ENSMUSG00000044519 | Zfp488 | ortholog_one2one | 72.7003 | ENSG00000265763 | ZNF488 | ortholog_one2one | 49.8516 | NA | NA | NA | NA | NA | NA | 382867 | 382867 | 118738 | 118738 |
| ENSMOCG00000002172 | 71.570685 | -0.4254714 | 0.1557600 | 0.0000362 | 0.0003970 | 101997411 | Rprm | protein_coding | 101997411 | Rprm | ENSMUSG00000075334 | Rprm | ortholog_one2one | 99.0826 | ENSG00000177519 | RPRM | ortholog_one2one | 98.1651 | NA | NA | NA | NA | NA | NA | 67874 | 67874 | 56475 | 56475 |
| ENSMOCG00000013379 | 117.797250 | -0.3858373 | 0.1376442 | 0.0000364 | 0.0003993 | 101996609 | Nr2f1 | protein_coding | 101996609 | Nr2f1 | ENSMUSG00000069171 | Nr2f1 | ortholog_one2one | 100.0000 | ENSG00000175745 | NR2F1 | ortholog_one2one | 99.5238 | NA | NA | NA | NA | NA | NA | 13865 | 13865 | 7025 | 7025 |
| ENSMOCG00000020781 | 264.085738 | -0.2778019 | 0.0870239 | 0.0000370 | 0.0004040 | 102001810 | 5730455P16Rik | protein_coding | 102001810 | 5730455P16Rik | ENSMUSG00000057181 | 5730455P16Rik | ortholog_one2one | 93.5897 | ENSG00000108666 | C17orf75 | ortholog_one2one | 87.9487 | NA | NA | NA | NA | NA | NA | 70591 | 70591 | 64149 | 64149 |
| ENSMOCG00000012587 | 237.700184 | -0.3367846 | 0.1145006 | 0.0000374 | 0.0004088 | 101996570 | Hes5 | protein_coding | 101996570 | Hes5 | ENSMUSG00000048001 | Hes5 | ortholog_one2one | 93.3735 | ENSG00000197921 | HES5 | ortholog_one2one | 89.7590 | NA | NA | NA | NA | NA | NA | 15208 | 15208 | 388585 | 388585 |
| ENSMOCG00000013928 | 457.774777 | -0.2627058 | 0.0807833 | 0.0000375 | 0.0004088 | NA | protein_coding | NA | NA | ENSG00000174748 | RPL15 | ortholog_one2many | 97.8947 | NA | NA | NA | NA | NA | NA | NA | NA | 6138 | 6138 | |||||
| ENSMOCG00000018797 | 101.835270 | 0.3962005 | 0.1434871 | 0.0000386 | 0.0004199 | 101987843 | Ttc12 | protein_coding | 101987843 | Ttc12 | ENSMUSG00000040219 | Ttc12 | ortholog_one2one | 85.7955 | ENSG00000149292 | TTC12 | ortholog_one2one | 77.4148 | NA | NA | NA | NA | NA | NA | 235330 | 235330 | 54970 | 54970 |
| ENSMOCG00000015348 | 84.754417 | 0.4133164 | 0.1515627 | 0.0000389 | 0.0004221 | 101979926 | Snapc5 | protein_coding | 101979926 | Snapc5 | ENSMUSG00000032398 | Snapc5 | ortholog_one2one | 87.7551 | ENSG00000174446 | SNAPC5 | ortholog_one2one | 84.6939 | NA | NA | NA | NA | NA | NA | 330959 | 330959 | 10302 | 10302 |
| ENSMOCG00000021518 | 236.008180 | -0.3053235 | 0.1000226 | 0.0000392 | 0.0004255 | 101998013 | Fgf11 | protein_coding | 101998013 | Fgf11 | ENSMUSG00000042826 | Fgf11 | ortholog_one2one | 99.1111 | ENSG00000161958 | FGF11 | ortholog_one2one | 96.8889 | NA | NA | NA | NA | NA | NA | 14166 | 14166 | 2256 | 2256 |
| ENSMOCG00000004580 | 169.007242 | 0.2928763 | 0.0943876 | 0.0000397 | 0.0004304 | 102000458 | Zfp661 | protein_coding | 102000458 | Zfp661 | ENSMUSG00000034800 | Zfp661 | ortholog_one2one | 79.8144 | ENSG00000275111 | ZNF2 | ortholog_one2one | 76.3341 | NA | NA | NA | NA | NA | NA | 72180 | 72180 | 7549 | 7549 |
| ENSMOCG00000019682 | 358.676040 | -0.5078590 | 0.1938709 | 0.0000405 | 0.0004364 | 101983450 | Gpr101 | protein_coding | 101983450 | Gpr101 | ENSMUSG00000036357 | Gpr101 | ortholog_one2one | 69.6607 | ENSG00000165370 | GPR101 | ortholog_one2one | 69.2615 | NA | NA | NA | NA | NA | NA | 245424 | 245424 | 83550 | 83550 |
| ENSMOCG00000002225 | 338.709389 | 0.9997742 | 0.5382361 | 0.0000407 | 0.0004380 | 101980084 | processed_pseudogene | 101980084 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000002420 | 37.736897 | -0.6083812 | 0.2387745 | 0.0000430 | 0.0004597 | NA | snoRNA | NA | ENSMUSG00000064417 | DQ267102 | ortholog_one2many | 83.3333 | ENSG00000200150 | ortholog_one2many | 59.7222 | NA | NA | NA | NA | NA | NA | 100861572 | 100861572 | 124903418 | 124903418 | |||
| ENSMOCG00000015351 | 17.707350 | -0.6242515 | 0.2465701 | 0.0000436 | 0.0004654 | 102001092 | Tuft1 | protein_coding | 102001092 | Tuft1 | ENSMUSG00000005968 | Tuft1 | ortholog_one2one | 90.2564 | ENSG00000143367 | TUFT1 | ortholog_one2one | 88.7179 | NA | NA | NA | NA | NA | NA | 22156 | 22156 | 7286 | 7286 |
| ENSMOCG00000012534 | 42.258085 | -0.5237137 | 0.2026812 | 0.0000437 | 0.0004660 | 101994493 | Miip | protein_coding | 101994493 | Miip | ENSMUSG00000029022 | Miip | ortholog_one2one | 75.8442 | ENSG00000116691 | MIIP | ortholog_one2one | 58.7013 | NA | NA | NA | NA | NA | NA | 28010 | 28010 | 60672 | 60672 |
| ENSMOCG00000015490 | 43.829391 | -0.5241278 | 0.2030854 | 0.0000441 | 0.0004694 | NA | Ddx11 | protein_coding | NA | Ddx11 | ENSMUSG00000035842 | Ddx11 | ortholog_one2one | 88.8644 | ENSG00000013573 | DDX11 | ortholog_one2one | 79.3826 | NA | NA | NA | NA | NA | NA | 320209 | 320209 | 1663 | 1663 |
| ENSMOCG00000019022 | 55.289443 | -0.3668932 | 0.1316982 | 0.0000445 | 0.0004739 | 101985248 | protein_coding | 101985248 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000022101 | 23.823481 | -0.6760933 | 0.2734925 | 0.0000451 | 0.0004795 | 101993738 | Jchain | protein_coding | 101993738 | Jchain | ENSMUSG00000067149 | Jchain | ortholog_one2one | 82.5000 | ENSG00000132465 | JCHAIN | ortholog_one2one | 74.3750 | NA | NA | NA | NA | NA | NA | 16069 | 16069 | 3512 | 3512 |
| ENSMOCG00000006710 | 225.338597 | -0.2659577 | 0.0838121 | 0.0000459 | 0.0004869 | 101992082 | Ccdc85a | protein_coding | 101992082 | Ccdc85a | ENSMUSG00000032878 | Ccdc85a | ortholog_one2one | 95.2294 | ENSG00000055813 | CCDC85A | ortholog_one2one | 93.0275 | NA | NA | NA | NA | NA | NA | 216613 | 216613 | 114800 | 114800 |
| ENSMOCG00000005064 | 15.947093 | -0.7188184 | 0.2986720 | 0.0000462 | 0.0004897 | 101990144 | MC4R | protein_coding | 101990144 | MC4R | ENSMUSG00000047259 | Mc4r | ortholog_one2one | 96.9880 | ENSG00000166603 | MC4R | ortholog_one2one | 95.1807 | NA | NA | NA | NA | NA | NA | 17202 | 17202 | 4160 | 4160 |
| ENSMOCG00000004277 | 112.938155 | 0.2508090 | 0.0776762 | 0.0000469 | 0.0004948 | 101982585 | protein_coding | 101982585 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000017444 | 24.561731 | -0.5815960 | 0.2307501 | 0.0000479 | 0.0005037 | NA | protein_coding | NA | ENSMUSG00000031730 | Dhodh | ortholog_one2one | 95.6835 | ENSG00000102967 | DHODH | ortholog_one2one | 89.2086 | NA | NA | NA | NA | NA | NA | 56749 | 56749 | 1723 | 1723 | ||
| ENSMOCG00000009021 | 141.970380 | 0.2809602 | 0.0908415 | 0.0000481 | 0.0005051 | 101985372 | Rerg | protein_coding | 101985372 | Rerg | ENSMUSG00000030222 | Rerg | ortholog_one2one | 99.4975 | ENSG00000134533 | RERG | ortholog_one2one | 97.9900 | NA | NA | NA | NA | NA | NA | 232441 | 232441 | 85004 | 85004 |
| ENSMOCG00000007454 | 114.276164 | -0.3117617 | 0.1055342 | 0.0000485 | 0.0005086 | 101997358 | Nqo2 | protein_coding | 101997358 | Nqo2 | ENSMUSG00000046949 | Nqo2 | ortholog_one2one | 90.0433 | ENSG00000124588 | NQO2 | ortholog_one2one | 80.5195 | NA | NA | NA | NA | NA | NA | 18105 | 18105 | 4835 | 4835 |
| ENSMOCG00000021675 | 49.852649 | 0.5313835 | 0.2097212 | 0.0000496 | 0.0005184 | 101991688 | Gask1b | protein_coding | 101991688 | Gask1b | ENSMUSG00000027955 | Gask1b | ortholog_one2one | 88.9961 | ENSG00000164125 | GASK1B | ortholog_one2one | 82.8185 | NA | NA | NA | NA | NA | NA | 68659 | 68659 | 51313 | 51313 |
| ENSMOCG00000005238 | 137.929212 | 0.2981980 | 0.0992257 | 0.0000496 | 0.0005184 | NA | Galnt14 | protein_coding | NA | Galnt14 | ENSMUSG00000024064 | Galnt14 | ortholog_one2one | 96.8460 | ENSG00000158089 | GALNT14 | ortholog_one2one | 91.8367 | NA | NA | NA | NA | NA | NA | 71685 | 71685 | 79623 | 79623 |
| ENSMOCG00000003317 | 17.421747 | -0.5136932 | 0.2034229 | 0.0000522 | 0.0005425 | 102002368 | Ttc22 | protein_coding | 102002368 | Ttc22 | ENSMUSG00000034919 | Ttc22 | ortholog_one2one | 87.1750 | ENSG00000006555 | TTC22 | ortholog_one2one | 82.1490 | NA | NA | NA | NA | NA | NA | 230576 | 230576 | 55001 | 55001 |
| ENSMOCG00000003788 | 123.074771 | -0.2809607 | 0.0916504 | 0.0000522 | 0.0005425 | 101983435 | Ccdc184 | protein_coding | 101983435 | Ccdc184 | ENSMUSG00000029875 | Ccdc184 | ortholog_one2one | 93.8144 | ENSG00000177875 | CCDC184 | ortholog_one2one | 92.2680 | NA | NA | NA | NA | NA | NA | 239650 | 239650 | 387856 | 387856 |
| ENSMOCG00000017009 | 23.275304 | 0.6036066 | 0.2447690 | 0.0000529 | 0.0005483 | 101979423 | protein_coding | 101979423 | NA | ENSG00000171217 | CLDN20 | ortholog_one2one | 76.2557 | NA | NA | NA | NA | NA | NA | NA | NA | 49861 | 49861 | |||||
| ENSMOCG00000004622 | 4673.733645 | 0.2515082 | 0.0789069 | 0.0000529 | 0.0005483 | 101986788 | Copg1 | protein_coding | 101986788 | Copg1 | ENSMUSG00000030058 | Copg1 | ortholog_one2one | 99.5423 | ENSG00000181789 | COPG1 | ortholog_one2one | 97.2540 | NA | NA | NA | NA | NA | NA | 54161 | 54161 | 22820 | 22820 |
| ENSMOCG00000004719 | 88.637546 | -0.2586403 | 0.0819187 | 0.0000531 | 0.0005496 | 101999357 | Tbcc | protein_coding | 101999357 | Tbcc | ENSMUSG00000036430 | Tbcc | ortholog_one2one | 89.1176 | ENSG00000124659 | TBCC | ortholog_one2one | 77.0588 | NA | NA | NA | NA | NA | NA | 72726 | 72726 | 6903 | 6903 |
| ENSMOCG00000017740 | 802.326255 | -0.2637060 | 0.0843731 | 0.0000548 | 0.0005655 | 101983066 | Extl2 | protein_coding | 101983066 | Extl2 | ENSMUSG00000027963 | Extl2 | ortholog_one2one | 89.7281 | ENSG00000162694 | EXTL2 | ortholog_one2one | 84.5921 | NA | NA | NA | NA | NA | NA | 58193 | 58193 | 2135 | 2135 |
| ENSMOCG00000014578 | 16.746027 | -0.8751449 | 0.4451461 | 0.0000549 | 0.0005657 | 101998526 | Npas1 | protein_coding | 101998526 | Npas1 | ENSMUSG00000001988 | Npas1 | ortholog_one2one | 94.1176 | ENSG00000130751 | NPAS1 | ortholog_one2one | 86.2185 | NA | NA | NA | NA | NA | NA | 18142 | 18142 | 4861 | 4861 |
| ENSMOCG00000010156 | 350.673592 | 0.2704906 | 0.0875382 | 0.0000558 | 0.0005749 | 101982722 | Golga5 | protein_coding | 101982722 | Golga5 | ENSMUSG00000021192 | Golga5 | ortholog_one2one | 89.8491 | ENSG00000066455 | GOLGA5 | ortholog_one2one | 85.7339 | NA | NA | NA | NA | NA | NA | 27277 | 27277 | 9950 | 9950 |
| ENSMOCG00000018487 | 50.726689 | -0.3281091 | 0.1159206 | 0.0000574 | 0.0005896 | 101995335 | Slc30a10 | protein_coding | 101995335 | Slc30a10 | ENSMUSG00000026614 | Slc30a10 | ortholog_one2one | 86.8922 | ENSG00000196660 | SLC30A10 | ortholog_one2one | 79.7040 | NA | NA | NA | NA | NA | NA | 226781 | 226781 | 55532 | 55532 |
| ENSMOCG00000013659 | 61.096284 | -0.4433385 | 0.1737776 | 0.0000577 | 0.0005920 | 101992839 | Serpinf1 | protein_coding | 101992839 | Serpinf1 | ENSMUSG00000000753 | Serpinf1 | ortholog_one2one | 94.9640 | ENSG00000132386 | SERPINF1 | ortholog_one2one | 86.8106 | NA | NA | NA | NA | NA | NA | 20317 | 20317 | 5176 | 5176 |
| ENSMOCG00000005382 | 92.641082 | -0.2842115 | 0.0942405 | 0.0000580 | 0.0005939 | 101990399 | 1700017B05Rik | protein_coding | 101990399 | 1700017B05Rik | ENSMUSG00000032300 | 1700017B05Rik | ortholog_one2one | 87.2798 | ENSG00000167173 | C15orf39 | ortholog_one2one | 75.8317 | NA | NA | NA | NA | NA | NA | 74211 | 74211 | 56905 | 56905 |
| ENSMOCG00000013111 | 100.086050 | -0.3692769 | 0.1381492 | 0.0000610 | 0.0006192 | 102000777 | Coro6 | protein_coding | 102000777 | Coro6 | ENSMUSG00000020836 | Coro6 | ortholog_one2one | 94.4798 | ENSG00000167549 | CORO6 | ortholog_one2one | 92.9936 | NA | NA | NA | NA | NA | NA | 216961 | 216961 | 84940 | 84940 |
| ENSMOCG00000016707 | 51.090210 | -0.4776758 | 0.1919532 | 0.0000623 | 0.0006312 | 101994744 | Lrrc46 | protein_coding | 101994744 | Lrrc46 | ENSMUSG00000020878 | Lrrc46 | ortholog_one2one | 78.1538 | ENSG00000141294 | LRRC46 | ortholog_one2one | 70.4615 | NA | NA | NA | NA | NA | NA | 69297 | 69297 | 90506 | 90506 |
| ENSMOCG00000022333 | 24.867187 | 0.4255599 | 0.1675626 | 0.0000640 | 0.0006446 | 101993767 | protein_coding | 101993767 | ENSMUSG00000078931 | ortholog_one2one | 86.1472 | ENSG00000258429 | ortholog_one2one | 77.4892 | NA | NA | NA | NA | NA | NA | 68023 | 68023 | 64146 | 64146 | ||||
| ENSMOCG00000009724 | 167.432576 | 0.2634448 | 0.0856739 | 0.0000641 | 0.0006452 | 101980118 | Fyco1 | protein_coding | 101980118 | Fyco1 | ENSMUSG00000025241 | Fyco1 | ortholog_one2one | 87.5466 | ENSG00000163820 | FYCO1 | ortholog_one2one | 78.0015 | NA | NA | NA | NA | NA | NA | 17281 | 17281 | 79443 | 79443 |
| ENSMOCG00000012066 | 184.011528 | 0.2524942 | 0.0809146 | 0.0000643 | 0.0006465 | 101992975 | Ankrd33b | protein_coding | 101992975 | Ankrd33b | ENSMUSG00000022237 | Ankrd33b | ortholog_one2one | 89.6050 | ENSG00000164236 | ANKRD33B | ortholog_one2one | 77.5468 | NA | NA | NA | NA | NA | NA | 67434 | 67434 | 651746 | 651746 |
| ENSMOCG00000010244 | 120.549546 | -0.3056649 | 0.1066476 | 0.0000678 | 0.0006777 | NA | protein_coding | NA | ENSMUSG00000052981 | Ube2ql1 | ortholog_one2one | 86.3309 | ENSG00000215218 | UBE2QL1 | ortholog_one2one | 86.3309 | NA | NA | NA | NA | NA | NA | 76980 | 76980 | 134111 | 134111 | ||
| ENSMOCG00000015441 | 183.393329 | -0.3094331 | 0.1088120 | 0.0000689 | 0.0006880 | 101985485 | Cntrl | protein_coding | 101985485 | Cntrl | ENSMUSG00000057110 | Cntrl | ortholog_one2one | 86.4240 | ENSG00000119397 | CNTRL | ortholog_one2one | 81.2848 | NA | NA | NA | NA | NA | NA | 26920 | 26920 | 11064 | 11064 |
| ENSMOCG00000011501 | 192.887659 | -0.3508847 | 0.1307338 | 0.0000693 | 0.0006911 | 101988500 | Nptx2 | protein_coding | 101988500 | Nptx2 | ENSMUSG00000059991 | Nptx2 | ortholog_one2one | 97.4537 | ENSG00000106236 | NPTX2 | ortholog_one2one | 95.6019 | NA | NA | NA | NA | NA | NA | 53324 | 53324 | 4885 | 4885 |
| ENSMOCG00000005124 | 67.137320 | -0.4398752 | 0.1769655 | 0.0000705 | 0.0007009 | 101982727 | Ret | protein_coding | 101982727 | Ret | ENSMUSG00000030110 | Ret | ortholog_one2one | 90.6643 | ENSG00000165731 | RET | ortholog_one2one | 85.1885 | NA | NA | NA | NA | NA | NA | 19713 | 19713 | 5979 | 5979 |
| ENSMOCG00000020902 | 26.522989 | 0.4900402 | 0.2021175 | 0.0000722 | 0.0007162 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000007382 | 25.116582 | -0.4716309 | 0.1936264 | 0.0000733 | 0.0007267 | 101980208 | Fndc10 | protein_coding | 101980208 | Fndc10 | ENSMUSG00000074738 | Fndc10 | ortholog_one2one | 93.2735 | ENSG00000228594 | FNDC10 | ortholog_one2one | 84.3049 | NA | NA | NA | NA | NA | NA | 230991 | 230991 | 643988 | 643988 |
| ENSMOCG00000019385 | 19.900891 | -0.8571588 | 0.4770240 | 0.0000742 | 0.0007341 | 101991263 | Dgkk | protein_coding | 101991263 | Dgkk | ENSMUSG00000062393 | Dgkk | ortholog_one2one | 78.8151 | ENSG00000274588 | DGKK | ortholog_one2one | 73.2495 | NA | NA | NA | NA | NA | NA | 331374 | 331374 | 139189 | 139189 |
| ENSMOCG00000003523 | 58.496626 | -0.3614970 | 0.1377631 | 0.0000749 | 0.0007395 | 101979946 | Pyroxd2 | protein_coding | 101979946 | Pyroxd2 | ENSMUSG00000060224 | Pyroxd2 | ortholog_one2one | 90.5336 | ENSG00000119943 | PYROXD2 | ortholog_one2one | 85.0258 | NA | NA | NA | NA | NA | NA | 74580 | 74580 | 84795 | 84795 |
| ENSMOCG00000018328 | 360.430658 | 0.2637174 | 0.0873156 | 0.0000751 | 0.0007410 | 101996435 | Slc35d3 | protein_coding | 101996435 | Slc35d3 | ENSMUSG00000050473 | Slc35d3 | ortholog_one2one | 92.1801 | ENSG00000182747 | SLC35D3 | ortholog_one2one | 91.9431 | NA | NA | NA | NA | NA | NA | 76157 | 76157 | 340146 | 340146 |
| ENSMOCG00000019350 | 86.954641 | -0.4498437 | 0.1836311 | 0.0000753 | 0.0007423 | 101990904 | Col14a1 | protein_coding | 101990904 | Col14a1 | ENSMUSG00000022371 | Col14a1 | ortholog_one2one | 95.5481 | ENSG00000187955 | COL14A1 | ortholog_one2one | 89.8164 | NA | NA | NA | NA | NA | NA | 12818 | 12818 | 7373 | 7373 |
| ENSMOCG00000015540 | 101.438496 | -0.2836127 | 0.0969455 | 0.0000761 | 0.0007468 | NA | Sema6c | protein_coding | NA | Sema6c | ENSMUSG00000038777 | Sema6c | ortholog_one2one | 92.7336 | ENSG00000143434 | SEMA6C | ortholog_one2one | 86.3898 | NA | NA | NA | NA | NA | NA | 20360 | 20360 | 10500 | 10500 |
| ENSMOCG00000013465 | 53.505249 | -0.5782300 | 0.2477121 | 0.0000761 | 0.0007470 | 101983430 | Fuom | protein_coding | 101983430 | Fuom | ENSMUSG00000025466 | Fuom | ortholog_one2one | 77.7778 | ENSG00000148803 | FUOM | ortholog_one2one | 83.6601 | NA | NA | NA | NA | NA | NA | 69064 | 69064 | 282969 | 282969 |
| ENSMOCG00000015032 | 71.080724 | -0.2517148 | 0.0821301 | 0.0000768 | 0.0007526 | NA | protein_coding | NA | NA | ENSG00000169740 | ZNF32 | ortholog_one2many | 88.3117 | NA | NA | NA | NA | NA | NA | NA | NA | 7580 | 7580 | |||||
| ENSMOCG00000004510 | 46.150194 | -0.3276267 | 0.1203046 | 0.0000785 | 0.0007668 | 101988585 | Ctsh | protein_coding | 101988585 | Ctsh | ENSMUSG00000032359 | Ctsh | ortholog_one2one | 83.2335 | ENSG00000103811 | CTSH | ortholog_one2one | 79.9401 | NA | NA | NA | NA | NA | NA | 13036 | 13036 | 1512 | 1512 |
| ENSMOCG00000020373 | 98.988203 | -0.2816383 | 0.0964186 | 0.0000791 | 0.0007721 | 101979568 | Aldh3b1 | protein_coding | 101979568 | Aldh3b1 | ENSMUSG00000024885 | Aldh3b1 | ortholog_one2one | 91.4530 | ENSG00000006534 | ALDH3B1 | ortholog_one2one | 83.1197 | NA | NA | NA | NA | NA | NA | 67689 | 67689 | 221 | 221 |
| ENSMOCG00000008169 | 289.238331 | -0.2539561 | 0.0835635 | 0.0000806 | 0.0007849 | 101993657 | Sox2 | protein_coding | 101993657 | Sox2 | ENSMUSG00000074637 | Sox2 | ortholog_one2one | 99.6865 | ENSG00000181449 | SOX2 | ortholog_one2one | 97.8056 | NA | NA | NA | NA | NA | NA | 20674 | 20674 | 6657 | 6657 |
| ENSMOCG00000016024 | 27.548773 | -0.4171517 | 0.1695309 | 0.0000833 | 0.0008072 | 101996043 | Egflam | protein_coding | 101996043 | Egflam | ENSMUSG00000042961 | Egflam | ortholog_one2one | 85.0099 | ENSG00000164318 | EGFLAM | ortholog_one2one | 81.0651 | NA | NA | NA | NA | NA | NA | 268780 | 268780 | 133584 | 133584 |
| ENSMOCG00000008662 | 10.852101 | -0.7047793 | 0.3329540 | 0.0000839 | 0.0008109 | 101987649 | protein_coding | 101987649 | ENSMUSG00000022949 | Clic6 | ortholog_one2one | 97.1429 | ENSG00000159212 | CLIC6 | ortholog_one2one | 96.1905 | NA | NA | NA | NA | NA | NA | 209195 | 209195 | 54102 | 54102 | ||
| ENSMOCG00000015561 | 49.154334 | -0.3361063 | 0.1261239 | 0.0000846 | 0.0008171 | 101997434 | Sgsh | protein_coding | 101997434 | Sgsh | ENSMUSG00000005043 | Sgsh | ortholog_one2one | 92.0319 | ENSG00000181523 | SGSH | ortholog_one2one | 87.8486 | NA | NA | NA | NA | NA | NA | 27029 | 27029 | 6448 | 6448 |
| ENSMOCG00000020681 | 32.463321 | 0.3422341 | 0.1296258 | 0.0000852 | 0.0008218 | 101987879 | Otc | protein_coding | 101987879 | Otc | ENSMUSG00000031173 | Otc | ortholog_one2one | 95.7627 | ENSG00000036473 | OTC | ortholog_one2one | 92.6554 | NA | NA | NA | NA | NA | NA | 18416 | 18416 | 5009 | 5009 |
| ENSMOCG00000008654 | 41.499051 | 0.3095929 | 0.1119131 | 0.0000857 | 0.0008250 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000000650 | 105.563226 | -0.2774674 | 0.0953574 | 0.0000863 | 0.0008306 | 101979890 | Invs | protein_coding | 101979890 | Invs | ENSMUSG00000028344 | Invs | ortholog_one2one | 88.1179 | ENSG00000119509 | INVS | ortholog_one2one | 81.4639 | NA | NA | NA | NA | NA | NA | 16348 | 16348 | 27130 | 27130 |
| ENSMOCG00000012344 | 1011.071459 | -0.2577317 | 0.0863595 | 0.0000903 | 0.0008623 | 101996310 | Ndrg1 | protein_coding | 101996310 | Ndrg1 | ENSMUSG00000005125 | Ndrg1 | ortholog_one2one | 98.7310 | ENSG00000104419 | NDRG1 | ortholog_one2one | 93.9086 | NA | NA | NA | NA | NA | NA | 17988 | 17988 | 10397 | 10397 |
| ENSMOCG00000019978 | 57.181258 | -0.4468638 | 0.1873683 | 0.0000911 | 0.0008694 | 101978948 | Rassf4 | protein_coding | 101978948 | Rassf4 | ENSMUSG00000042129 | Rassf4 | ortholog_one2one | 93.7500 | ENSG00000107551 | RASSF4 | ortholog_one2one | 86.8750 | NA | NA | NA | NA | NA | NA | 213391 | 213391 | 83937 | 83937 |
| ENSMOCG00000016831 | 96.155966 | -0.2950168 | 0.1050795 | 0.0000916 | 0.0008731 | 101999247 | Galk1 | protein_coding | 101999247 | Galk1 | ENSMUSG00000020766 | Galk1 | ortholog_one2one | 93.6225 | ENSG00000108479 | GALK1 | ortholog_one2one | 91.0714 | NA | NA | NA | NA | NA | NA | 14635 | 14635 | 2584 | 2584 |
| ENSMOCG00000006390 | 58.427572 | -0.3716532 | 0.1472849 | 0.0000918 | 0.0008748 | 102001376 | Mthfd2l | protein_coding | 102001376 | Mthfd2l | ENSMUSG00000029376 | Mthfd2l | ortholog_one2one | 93.7870 | ENSG00000163738 | MTHFD2L | ortholog_one2one | 87.8698 | NA | NA | NA | NA | NA | NA | 665563 | 665563 | 441024 | 441024 |
| ENSMOCG00000008385 | 56.027336 | -0.7513031 | 0.3894940 | 0.0000953 | 0.0009042 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000002738 | 16.598586 | -0.5013962 | 0.2173333 | 0.0000961 | 0.0009091 | 101993330 | Gas1 | protein_coding | 101993330 | Gas1 | ENSMUSG00000052957 | Gas1 | ortholog_one2one | 95.0292 | ENSG00000180447 | GAS1 | ortholog_one2one | 85.6725 | NA | NA | NA | NA | NA | NA | 14451 | 14451 | 2619 | 2619 |
| ENSMOCG00000022989 | 97.259050 | -0.4423327 | 0.1866370 | 0.0000965 | 0.0009120 | NA | Sspo | protein_coding | NA | Sspo | ENSMUSG00000029797 | Sspo | ortholog_one2one | 84.6907 | NA | NA | NA | NA | NA | NA | NA | 243369 | 243369 | NA | NA | |||
| ENSMOCG00000014106 | 14.491658 | 0.6591551 | 0.3132670 | 0.0001005 | 0.0009446 | 101980271 | Arhgap40 | protein_coding | 101980271 | Arhgap40 | ENSMUSG00000074625 | Arhgap40 | ortholog_one2one | 86.1813 | ENSG00000124143 | ARHGAP40 | ortholog_one2one | 72.0654 | NA | NA | NA | NA | NA | NA | 545481 | 545481 | 343578 | 343578 |
| ENSMOCG00000015195 | 1957.500285 | 0.3505670 | 0.1373250 | 0.0001006 | 0.0009453 | 101983070 | Cfap54 | protein_coding | 101983070 | Cfap54 | ENSMUSG00000020014 | Cfap54 | ortholog_one2one | 81.1351 | ENSG00000188596 | CFAP54 | ortholog_one2one | 73.1135 | NA | NA | NA | NA | NA | NA | 380654 | 380654 | 144535 | 144535 |
| ENSMOCG00000010410 | 72.748876 | 0.2705641 | 0.0937257 | 0.0001010 | 0.0009487 | NA | Slc25a30 | protein_coding | NA | Slc25a30 | ENSMUSG00000022003 | Slc25a30 | ortholog_one2one | 95.8477 | ENSG00000174032 | SLC25A30 | ortholog_one2one | 92.7336 | NA | NA | NA | NA | NA | NA | 67554 | 67554 | 253512 | 253512 |
| ENSMOCG00000001947 | 1096.857084 | -0.3313429 | 0.1269214 | 0.0001033 | 0.0009681 | 101988427 | Cldn11 | protein_coding | 101988427 | Cldn11 | ENSMUSG00000037625 | Cldn11 | ortholog_one2one | 100.0000 | ENSG00000013297 | CLDN11 | ortholog_one2one | 94.2029 | NA | NA | NA | NA | NA | NA | 18417 | 18417 | 5010 | 5010 |
| ENSMOCG00000020565 | 59.833958 | -0.4323142 | 0.1833996 | 0.0001039 | 0.0009723 | 101996482 | Dlec1 | protein_coding | 101996482 | Dlec1 | ENSMUSG00000038060 | Dlec1 | ortholog_one2one | 80.8511 | ENSG00000008226 | DLEC1 | ortholog_one2one | 74.1806 | NA | NA | NA | NA | NA | NA | 320256 | 320256 | 9940 | 9940 |
| ENSMOCG00000000763 | 11.120983 | 0.8022477 | 0.4713361 | 0.0001044 | 0.0009762 | NA | Stkld1 | protein_coding | NA | Stkld1 | ENSMUSG00000049897 | Stkld1 | ortholog_one2one | 77.6758 | ENSG00000198870 | STKLD1 | ortholog_one2one | 57.1865 | NA | NA | NA | NA | NA | NA | 279029 | 279029 | 169436 | 169436 |
| ENSMOCG00000018461 | 38.792181 | -0.6851857 | 0.3381491 | 0.0001056 | 0.0009864 | 101988318 | P2ry2 | protein_coding | 101988318 | P2ry2 | ENSMUSG00000032860 | P2ry2 | ortholog_one2one | 92.5729 | ENSG00000175591 | P2RY2 | ortholog_one2one | 88.0637 | NA | NA | NA | NA | NA | NA | 18442 | 18442 | 5029 | 5029 |
| ENSMOCG00000001544 | 24.984976 | 0.6246784 | 0.2932799 | 0.0001065 | 0.0009929 | 101998583 | Crispld1 | protein_coding | 101998583 | Crispld1 | ENSMUSG00000025776 | Crispld1 | ortholog_one2one | 96.8000 | ENSG00000121005 | CRISPLD1 | ortholog_one2one | 95.0000 | NA | NA | NA | NA | NA | NA | 83691 | 83691 | 83690 | 83690 |
| ENSMOCG00000020649 | 70.405427 | -0.3123888 | 0.1170459 | 0.0001086 | 0.0010083 | 101998234 | Pdlim2 | protein_coding | 101998234 | Pdlim2 | ENSMUSG00000022090 | Pdlim2 | ortholog_one2one | 87.1429 | ENSG00000120913 | PDLIM2 | ortholog_one2one | 77.7143 | NA | NA | NA | NA | NA | NA | 213019 | 213019 | 64236 | 64236 |
| ENSMOCG00000019376 | 50.997669 | 0.3005120 | 0.1105974 | 0.0001098 | 0.0010183 | 101992358 | protein_coding | 101992358 | NA | ENSG00000105497 | ZNF175 | ortholog_one2one | 48.9149 | NA | NA | NA | NA | NA | NA | NA | NA | 7728 | 7728 | |||||
| ENSMOCG00000018170 | 26.497521 | -0.4017259 | 0.1683295 | 0.0001108 | 0.0010266 | NA | protein_coding | NA | ENSMUSG00000069170 | Adgrv1 | ortholog_one2many | 94.6541 | ENSG00000164199 | ADGRV1 | ortholog_one2many | 90.8805 | NA | NA | NA | NA | NA | NA | 110789 | 110789 | 84059 | 84059 | ||
| ENSMOCG00000009483 | 93.940463 | 0.2894261 | 0.1051235 | 0.0001145 | 0.0010570 | 101989759 | Gpx7 | protein_coding | 101989759 | Gpx7 | ENSMUSG00000028597 | Gpx7 | ortholog_one2one | 91.9355 | ENSG00000116157 | GPX7 | ortholog_one2one | 87.0968 | NA | NA | NA | NA | NA | NA | 67305 | 67305 | 2882 | 2882 |
| ENSMOCG00000004265 | 14.183216 | 1.1022171 | 1.4772398 | 0.0001149 | 0.0010599 | 101989304 | Cyp7a1 | protein_coding | 101989304 | Cyp7a1 | ENSMUSG00000028240 | Cyp7a1 | ortholog_one2one | 88.4462 | ENSG00000167910 | CYP7A1 | ortholog_one2one | 81.4741 | NA | NA | NA | NA | NA | NA | 13122 | 13122 | 1581 | 1581 |
| ENSMOCG00000017592 | 15.507378 | -0.4995464 | 0.2237588 | 0.0001169 | 0.0010748 | 101998186 | Crb2 | protein_coding | 101998186 | Crb2 | ENSMUSG00000035403 | Crb2 | ortholog_one2one | 85.1214 | ENSG00000148204 | CRB2 | ortholog_one2one | 75.9593 | NA | NA | NA | NA | NA | NA | 241324 | 241324 | 286204 | 286204 |
| ENSMOCG00000022796 | 192.411058 | -0.3774684 | 0.1560652 | 0.0001178 | 0.0010822 | 101987980 | Kyat3 | protein_coding | 101987980 | Kyat3 | ENSMUSG00000040213 | Kyat3 | ortholog_one2one | 88.3260 | ENSG00000137944 | KYAT3 | ortholog_one2one | 85.4626 | NA | NA | NA | NA | NA | NA | 229905 | 229905 | 56267 | 56267 |
| ENSMOCG00000021151 | 128.569165 | 0.2759080 | 0.0985769 | 0.0001204 | 0.0011026 | 101997047 | Mmrn2 | protein_coding | 101997047 | Mmrn2 | ENSMUSG00000041445 | Mmrn2 | ortholog_one2one | 79.7682 | ENSG00000173269 | MMRN2 | ortholog_one2one | 65.5427 | NA | NA | NA | NA | NA | NA | 105450 | 105450 | 79812 | 79812 |
| ENSMOCG00000013839 | 15.499249 | 0.6803963 | 0.3472700 | 0.0001207 | 0.0011034 | 101997729 | Krt77 | protein_coding | 101997729 | Krt77 | ENSMUSG00000067594 | Krt77 | ortholog_one2one | 83.5664 | ENSG00000189182 | KRT77 | ortholog_one2one | 75.6993 | NA | NA | NA | NA | NA | NA | 406220 | 406220 | 374454 | 374454 |
| ENSMOCG00000016578 | 37.147599 | 0.4908482 | 0.2211702 | 0.0001237 | 0.0011267 | 101979845 | Sstr2 | protein_coding | 101979845 | Sstr2 | ENSMUSG00000047904 | Sstr2 | ortholog_one2one | 96.4770 | ENSG00000180616 | SSTR2 | ortholog_one2one | 92.1409 | NA | NA | NA | NA | NA | NA | 20606 | 20606 | 6752 | 6752 |
| ENSMOCG00000017341 | 74.053529 | -0.2833870 | 0.1029366 | 0.0001238 | 0.0011267 | 101989353 | Scarf2 | protein_coding | 101989353 | Scarf2 | ENSMUSG00000012017 | Scarf2 | ortholog_one2one | 91.7167 | ENSG00000244486 | SCARF2 | ortholog_one2one | 89.3157 | NA | NA | NA | NA | NA | NA | 224024 | 224024 | 91179 | 91179 |
| ENSMOCG00000010879 | 30.783165 | -0.3465111 | 0.1395495 | 0.0001263 | 0.0011425 | 101989646 | Apoc1 | protein_coding | 101989646 | Apoc1 | ENSMUSG00000040564 | Apoc1 | ortholog_one2one | 82.9545 | ENSG00000130208 | APOC1 | ortholog_one2one | 64.7727 | NA | NA | NA | NA | NA | NA | 11812 | 11812 | 341 | 341 |
| ENSMOCG00000011710 | 59.463166 | 0.3156739 | 0.1215706 | 0.0001273 | 0.0011496 | 101985239 | Pgm5 | protein_coding | 101985239 | Pgm5 | ENSMUSG00000041731 | Pgm5 | ortholog_one2one | 98.9418 | ENSG00000154330 | PGM5 | ortholog_one2one | 97.5309 | NA | NA | NA | NA | NA | NA | 226041 | 226041 | 5239 | 5239 |
| ENSMOCG00000017300 | 106.250858 | 0.2611583 | 0.0916788 | 0.0001274 | 0.0011496 | NA | Pcdhga5 | protein_coding | NA | Pcdhga5 | ENSMUSG00000103567 | Pcdhga5 | ortholog_one2one | 89.4242 | ENSG00000253485 | PCDHGA5 | ortholog_one2one | 79.3185 | NA | NA | NA | NA | NA | NA | 93713 | 93713 | 56110 | 56110 |
| ENSMOCG00000020669 | 116.996051 | -0.2683134 | 0.0955981 | 0.0001303 | 0.0011705 | 101990635 | Ubxn2a | protein_coding | 101990635 | Ubxn2a | ENSMUSG00000020634 | Ubxn2a | ortholog_one2one | 93.4109 | ENSG00000173960 | UBXN2A | ortholog_one2one | 86.8217 | NA | NA | NA | NA | NA | NA | 217379 | 217379 | 165324 | 165324 |
| ENSMOCG00000011716 | 21.456847 | -0.3965579 | 0.1696658 | 0.0001305 | 0.0011713 | NA | Katnal2 | protein_coding | NA | Katnal2 | ENSMUSG00000025420 | Katnal2 | ortholog_one2one | 88.1633 | ENSG00000167216 | KATNAL2 | ortholog_one2one | 84.0816 | NA | NA | NA | NA | NA | NA | 71206 | 71206 | 83473 | 83473 |
| ENSMOCG00000004480 | 37.130533 | 0.3288773 | 0.1300230 | 0.0001322 | 0.0011853 | NA | U6 | snRNA | NA | U6 | ENSMUSG00000087871 | Gm26101 | ortholog_one2one | 61.7647 | ENSG00000252755 | RNU6-703P | ortholog_one2one | 83.3333 | NA | NA | NA | NA | NA | NA | 115487250 | 115487250 | NA | NA |
| ENSMOCG00000015947 | 80.495653 | -0.2721779 | 0.0978735 | 0.0001329 | 0.0011902 | 101999545 | Aass | protein_coding | 101999545 | Aass | ENSMUSG00000029695 | Aass | ortholog_one2one | 95.2484 | ENSG00000008311 | AASS | ortholog_one2one | 87.3650 | NA | NA | NA | NA | NA | NA | 30956 | 30956 | 10157 | 10157 |
| ENSMOCG00000012567 | 131.215244 | -0.3972239 | 0.1706318 | 0.0001333 | 0.0011919 | 101992874 | Ankrd35 | protein_coding | 101992874 | Ankrd35 | ENSMUSG00000038354 | Ankrd35 | ortholog_one2one | 88.4189 | ENSG00000198483 | ANKRD35 | ortholog_one2one | 81.7724 | NA | NA | NA | NA | NA | NA | 213121 | 213121 | 148741 | 148741 |
| ENSMOCG00000011264 | 11.659147 | -0.7193056 | 0.4024714 | 0.0001338 | 0.0011953 | 101985030 | Rab37 | protein_coding | 101985030 | Rab37 | ENSMUSG00000020732 | Rab37 | ortholog_one2one | 97.7579 | ENSG00000172794 | RAB37 | ortholog_one2one | 95.0673 | NA | NA | NA | NA | NA | NA | 58222 | 58222 | 326624 | 326624 |
| ENSMOCG00000019767 | 23.579478 | 0.5759463 | 0.2756973 | 0.0001339 | 0.0011957 | 101989091 | protein_coding | 101989091 | NA | ENSG00000162482 | AKR7A3 | ortholog_one2one | 78.3217 | NA | NA | NA | NA | NA | NA | NA | NA | 22977 | 22977 | |||||
| ENSMOCG00000008613 | 74.815510 | 0.2853062 | 0.1052692 | 0.0001357 | 0.0012096 | NA | Clmp | protein_coding | NA | Clmp | ENSMUSG00000032024 | Clmp | ortholog_one2one | 96.7742 | ENSG00000166250 | CLMP | ortholog_one2one | 93.0107 | NA | NA | NA | NA | NA | NA | 71566 | 71566 | 79827 | 79827 |
| ENSMOCG00000022707 | 199.072618 | -0.2649190 | 0.0946264 | 0.0001389 | 0.0012341 | 101996325 | Kcnc2 | protein_coding | 101996325 | Kcnc2 | ENSMUSG00000035681 | Kcnc2 | ortholog_one2one | 93.7008 | ENSG00000166006 | KCNC2 | ortholog_one2one | 91.9685 | NA | NA | NA | NA | NA | NA | 268345 | 268345 | 3747 | 3747 |
| ENSMOCG00000009133 | 56.269317 | -0.2779111 | 0.1016409 | 0.0001400 | 0.0012421 | 101991589 | Hrh1 | protein_coding | 101991589 | Hrh1 | ENSMUSG00000053004 | Hrh1 | ortholog_one2one | 88.8660 | ENSG00000196639 | HRH1 | ortholog_one2one | 79.5876 | NA | NA | NA | NA | NA | NA | 15465 | 15465 | 3269 | 3269 |
| ENSMOCG00000003491 | 14.241890 | -0.5525258 | 0.2645889 | 0.0001434 | 0.0012679 | 101994008 | Gnrh1 | protein_coding | 101994008 | Gnrh1 | ENSMUSG00000015812 | Gnrh1 | ortholog_one2one | 84.4444 | ENSG00000147437 | GNRH1 | ortholog_one2one | 73.3333 | NA | NA | NA | NA | NA | NA | 14714 | 14714 | 2796 | 2796 |
| ENSMOCG00000005703 | 89.417087 | -0.2593039 | 0.0921849 | 0.0001442 | 0.0012741 | 101980820 | Lingo2 | protein_coding | 101980820 | Lingo2 | ENSMUSG00000045083 | Lingo2 | ortholog_one2one | 97.6898 | ENSG00000174482 | LINGO2 | ortholog_one2one | 97.1947 | NA | NA | NA | NA | NA | NA | 242384 | 242384 | 158038 | 158038 |
| ENSMOCG00000013870 | 132.839121 | -0.2568746 | 0.0911353 | 0.0001465 | 0.0012919 | 101993996 | Plgrkt | protein_coding | 101993996 | Plgrkt | ENSMUSG00000016495 | Plgrkt | ortholog_one2one | 87.0748 | ENSG00000107020 | PLGRKT | ortholog_one2one | 82.9932 | NA | NA | NA | NA | NA | NA | 67759 | 67759 | 55848 | 55848 |
| ENSMOCG00000006437 | 201.368345 | -0.3708109 | 0.1575603 | 0.0001472 | 0.0012966 | 101985618 | Paqr6 | protein_coding | 101985618 | Paqr6 | ENSMUSG00000041423 | Paqr6 | ortholog_one2one | 88.3382 | ENSG00000160781 | PAQR6 | ortholog_one2one | 89.2128 | NA | NA | NA | NA | NA | NA | 68957 | 68957 | 79957 | 79957 |
| ENSMOCG00000005464 | 19.324607 | -0.4410435 | 0.2000417 | 0.0001510 | 0.0013225 | 101991896 | Gpr62 | protein_coding | 101991896 | Gpr62 | ENSMUSG00000091735 | Gpr62 | ortholog_one2one | 89.5480 | ENSG00000180929 | GPR62 | ortholog_one2one | 83.6158 | NA | NA | NA | NA | NA | NA | 436090 | 436090 | 118442 | 118442 |
| ENSMOCG00000008690 | 17.536944 | -0.4925677 | 0.2305443 | 0.0001515 | 0.0013256 | 101980838 | Tmem132c | protein_coding | 101980838 | Tmem132c | ENSMUSG00000034324 | Tmem132c | ortholog_one2one | 90.8964 | ENSG00000181234 | TMEM132C | ortholog_one2one | 80.3922 | NA | NA | NA | NA | NA | NA | 208213 | 208213 | 92293 | 92293 |
| ENSMOCG00000012933 | 15.370067 | -0.5388522 | 0.2597471 | 0.0001538 | 0.0013420 | 101999874 | Cfap73 | protein_coding | 101999874 | Cfap73 | ENSMUSG00000094282 | Cfap73 | ortholog_one2one | 61.0390 | ENSG00000186710 | CFAP73 | ortholog_one2one | 69.4805 | NA | NA | NA | NA | NA | NA | 546886 | 546886 | 387885 | 387885 |
| ENSMOCG00000015590 | 12.703253 | -0.5613151 | 0.2751894 | 0.0001556 | 0.0013539 | 101986637 | Zc3h12d | protein_coding | 101986637 | Zc3h12d | ENSMUSG00000039981 | Zc3h12d | ortholog_one2one | 81.3559 | ENSG00000178199 | ZC3H12D | ortholog_one2one | 64.0301 | NA | NA | NA | NA | NA | NA | 237256 | 237256 | 340152 | 340152 |
| ENSMOCG00000021805 | 30.166042 | -0.6243330 | 0.3240751 | 0.0001579 | 0.0013709 | 101979158 | protein_coding | 101979158 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000012270 | 71.427545 | -0.4053287 | 0.1807845 | 0.0001605 | 0.0013917 | 101996135 | protein_coding | 101996135 | ENSMUSG00000033036 | Ppihl | ortholog_many2many | 100.0000 | ENSG00000171960 | PPIH | ortholog_one2many | 100.0000 | ENSMUSG00000033036, ENSMUSG00000060288 | Ppihl, Ppih | 100, 88.8235 | ENSG00000171960, ENSG00000171960 | PPIH, PPIH | 100, 100 | NA | NA | 10465 | 10465 | ||
| ENSMOCG00000008555 | 15.683078 | -0.5968544 | 0.3030837 | 0.0001606 | 0.0013917 | NA | Podn | protein_coding | NA | Podn | ENSMUSG00000028600 | Podn | ortholog_one2one | 89.6203 | ENSG00000174348 | PODN | ortholog_one2one | 88.1013 | NA | NA | NA | NA | NA | NA | 242608 | 242608 | 127435 | 127435 |
| ENSMOCG00000016456 | 30.369313 | -0.3290081 | 0.1339842 | 0.0001606 | 0.0013917 | 101986901 | Clec11a | protein_coding | 101986901 | Clec11a | ENSMUSG00000004473 | Clec11a | ortholog_one2one | 86.5443 | ENSG00000105472 | CLEC11A | ortholog_one2one | 78.8991 | NA | NA | NA | NA | NA | NA | 20256 | 20256 | 6320 | 6320 |
| ENSMOCG00000009308 | 22.172142 | -0.4867283 | 0.2304956 | 0.0001640 | 0.0014144 | 101979730 | Myo3b | protein_coding | 101979730 | Myo3b | ENSMUSG00000042064 | Myo3b | ortholog_one2one | 90.1321 | ENSG00000071909 | MYO3B | ortholog_one2one | 86.7133 | NA | NA | NA | NA | NA | NA | 329421 | 329421 | 140469 | 140469 |
| ENSMOCG00000009018 | 97.850822 | -0.2524536 | 0.0901916 | 0.0001638 | 0.0014144 | 101984322 | Nnat | protein_coding | 101984322 | Nnat | ENSMUSG00000067786 | Nnat | ortholog_one2one | 75.0000 | NA | NA | NA | NA | NA | NA | NA | 18111 | 18111 | NA | NA | |||
| ENSMOCG00000004455 | 24.416383 | -0.6975122 | 0.4150904 | 0.0001698 | 0.0014578 | 101990775 | Cdhr4 | protein_coding | 101990775 | Cdhr4 | ENSMUSG00000032595 | Cdhr4 | ortholog_one2one | 81.3452 | ENSG00000187492 | CDHR4 | ortholog_one2one | 71.5736 | NA | NA | NA | NA | NA | NA | 69398 | 69398 | 389118 | 389118 |
| ENSMOCG00000003297 | 12.250206 | -0.6072883 | 0.3161986 | 0.0001699 | 0.0014580 | 101997414 | Nxph2 | protein_coding | 101997414 | Nxph2 | ENSMUSG00000069132 | Nxph2 | ortholog_one2one | 90.8046 | ENSG00000144227 | NXPH2 | ortholog_one2one | 95.0192 | NA | NA | NA | NA | NA | NA | 18232 | 18232 | 11249 | 11249 |
| ENSMOCG00000012957 | 30.403948 | -0.4688958 | 0.2215803 | 0.0001716 | 0.0014712 | 101994190 | Col8a2 | protein_coding | 101994190 | Col8a2 | ENSMUSG00000056174 | Col8a2 | ortholog_one2one | 96.4235 | ENSG00000171812 | COL8A2 | ortholog_one2one | 94.1345 | NA | NA | NA | NA | NA | NA | 329941 | 329941 | 1296 | 1296 |
| ENSMOCG00000010394 | 389.625098 | 0.3060751 | 0.1214838 | 0.0001743 | 0.0014917 | 102002738 | Tnxb | protein_coding | 102002738 | Tnxb | ENSMUSG00000033327 | Tnxb | ortholog_one2one | 81.1228 | ENSG00000168477 | TNXB | ortholog_one2one | 77.0190 | NA | NA | NA | NA | NA | NA | 81877 | 81877 | 7148 | 7148 |
| ENSMOCG00000003648 | 53.661646 | 0.2811769 | 0.1070293 | 0.0001787 | 0.0015245 | 101996922 | Ism1 | protein_coding | 101996922 | Ism1 | ENSMUSG00000074766 | Ism1 | ortholog_one2one | 96.7462 | ENSG00000101230 | ISM1 | ortholog_one2one | 92.8417 | NA | NA | NA | NA | NA | NA | 319909 | 319909 | 140862 | 140862 |
| ENSMOCG00000002519 | 112.110541 | -0.3384119 | 0.1423803 | 0.0001804 | 0.0015364 | 101982231 | Cbln4 | protein_coding | 101982231 | Cbln4 | ENSMUSG00000067578 | Cbln4 | ortholog_one2one | 97.0149 | ENSG00000054803 | CBLN4 | ortholog_one2one | 97.5124 | NA | NA | NA | NA | NA | NA | 228942 | 228942 | 140689 | 140689 |
| ENSMOCG00000022336 | 113.833915 | -0.4804166 | 0.2329106 | 0.0001886 | 0.0015982 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000011147 | 92.494703 | -0.3193939 | 0.1314280 | 0.0001896 | 0.0016057 | 101982224 | protein_coding | 101982224 | NA | ENSG00000171224 | FAM241B | ortholog_one2one | 93.3333 | NA | NA | NA | NA | NA | NA | NA | NA | 219738 | 219738 | |||||
| ENSMOCG00000007124 | 257.833093 | 0.5387055 | 0.2727264 | 0.0001919 | 0.0016237 | 102000462 | A2m | protein_coding | 102000462 | A2m | ENSMUSG00000030111 | A2m | ortholog_one2one | 76.8865 | ENSG00000175899 | A2M | ortholog_one2one | 68.7288 | NA | NA | NA | NA | NA | NA | 232345 | 232345 | 2 | 2 |
| ENSMOCG00000019233 | 32.156846 | 0.3848666 | 0.1736060 | 0.0001925 | 0.0016273 | 101999441 | protein_coding | 101999441 | ENSMUSG00000054690 | Emcn | ortholog_one2one | 57.4661 | ENSG00000164035 | EMCN | ortholog_one2one | 47.9638 | NA | NA | NA | NA | NA | NA | 59308 | 59308 | 51705 | 51705 | ||
| ENSMOCG00000020302 | 104.489401 | 0.2686351 | 0.1009753 | 0.0001928 | 0.0016286 | NA | Cmya5 | protein_coding | NA | Cmya5 | ENSMUSG00000047419 | Cmya5 | ortholog_one2one | 69.4841 | ENSG00000164309 | CMYA5 | ortholog_one2one | 61.1416 | NA | NA | NA | NA | NA | NA | 76469 | 76469 | 202333 | 202333 |
| ENSMOCG00000001440 | 84.248297 | -0.3127511 | 0.1279232 | 0.0001961 | 0.0016476 | 101990267 | Slc2a12 | protein_coding | 101990267 | Slc2a12 | ENSMUSG00000037490 | Slc2a12 | ortholog_one2one | 92.4316 | ENSG00000146411 | SLC2A12 | ortholog_one2one | 85.1852 | NA | NA | NA | NA | NA | NA | 353169 | 353169 | 154091 | 154091 |
| ENSMOCG00000022780 | 62.529244 | -0.3388444 | 0.1446666 | 0.0001965 | 0.0016493 | 102000522 | protein_coding | 102000522 | ENSMUSG00000028974 | Dffa | ortholog_one2many | 72.3127 | ENSG00000160049 | DFFA | ortholog_one2many | 67.1010 | NA | NA | NA | NA | NA | NA | 13347 | 13347 | 1676 | 1676 | ||
| ENSMOCG00000001240 | 155.619910 | 0.2818259 | 0.1089247 | 0.0001967 | 0.0016493 | 102000815 | Apln | protein_coding | 102000815 | Apln | ENSMUSG00000037010 | Apln | ortholog_one2one | 93.5065 | ENSG00000171388 | APLN | ortholog_one2one | 87.0130 | NA | NA | NA | NA | NA | NA | 30878 | 30878 | 8862 | 8862 |
| ENSMOCG00000008344 | 170.128044 | -0.2614882 | 0.0973033 | 0.0001972 | 0.0016511 | NA | Mybpc3 | protein_coding | NA | Mybpc3 | ENSMUSG00000002100 | Mybpc3 | ortholog_one2one | 95.7249 | ENSG00000134571 | MYBPC3 | ortholog_one2one | 91.4498 | NA | NA | NA | NA | NA | NA | 17868 | 17868 | 4607 | 4607 |
| ENSMOCG00000015860 | 58.601786 | -0.2922812 | 0.1152798 | 0.0001973 | 0.0016514 | 101988366 | Marchf3 | protein_coding | 101988366 | Marchf3 | ENSMUSG00000032656 | Marchf3 | ortholog_one2one | 99.2095 | ENSG00000173926 | MARCHF3 | ortholog_one2one | 98.4190 | NA | NA | NA | NA | NA | NA | 320253 | 320253 | 115123 | 115123 |
| ENSMOCG00000021296 | 25.574556 | -0.4728122 | 0.2302332 | 0.0001977 | 0.0016517 | 102002764 | Prlr | protein_coding | 102002764 | Prlr | ENSMUSG00000005268 | Prlr | ortholog_one2one | 81.4580 | ENSG00000113494 | PRLR | ortholog_one2one | 65.9271 | NA | NA | NA | NA | NA | NA | 19116 | 19116 | 5618 | 5618 |
| ENSMOCG00000022319 | 45.667063 | 0.3097317 | 0.1264959 | 0.0002009 | 0.0016760 | NA | protein_coding | NA | ENSMUSG00000041921 | Metap1d | ortholog_one2one | 79.4521 | ENSG00000172878 | METAP1D | ortholog_one2one | 78.7671 | NA | NA | NA | NA | NA | NA | 66559 | 66559 | 254042 | 254042 | ||
| ENSMOCG00000012694 | 34.486850 | -0.3832288 | 0.1741296 | 0.0002027 | 0.0016903 | 101978945 | Egln3 | protein_coding | 101978945 | Egln3 | ENSMUSG00000035105 | Egln3 | ortholog_one2one | 98.7179 | ENSG00000129521 | EGLN3 | ortholog_one2one | 97.8633 | NA | NA | NA | NA | NA | NA | 112407 | 112407 | 112399 | 112399 |
| ENSMOCG00000021489 | 113.033538 | -0.3096780 | 0.1273395 | 0.0002098 | 0.0017414 | 101984787 | Zdhhc22 | protein_coding | 101984787 | Zdhhc22 | ENSMUSG00000048483 | Zdhhc22 | ortholog_one2one | 97.3485 | ENSG00000177108 | ZDHHC22 | ortholog_one2one | 91.2879 | NA | NA | NA | NA | NA | NA | 238331 | 238331 | 283576 | 283576 |
| ENSMOCG00000016575 | 32.099982 | -0.4381549 | 0.2105706 | 0.0002099 | 0.0017415 | 101991721 | Cfap57 | protein_coding | 101991721 | Cfap57 | ENSMUSG00000028730 | Cfap57 | ortholog_one2one | 91.4331 | ENSG00000243710 | CFAP57 | ortholog_one2one | 90.3923 | NA | NA | NA | NA | NA | NA | 68625 | 68625 | 149465 | 149465 |
| ENSMOCG00000013951 | 92.230989 | -0.3277396 | 0.1398251 | 0.0002173 | 0.0017950 | 101993230 | Armc7 | protein_coding | 101993230 | Armc7 | ENSMUSG00000057219 | Armc7 | ortholog_one2one | 91.4141 | ENSG00000125449 | ARMC7 | ortholog_one2one | 86.3636 | NA | NA | NA | NA | NA | NA | 276905 | 276905 | 79637 | 79637 |
| ENSMOCG00000006311 | 45.386612 | 0.5027414 | 0.2550916 | 0.0002177 | 0.0017975 | 101986437 | Galnt15 | protein_coding | 101986437 | Galnt15 | ENSMUSG00000021903 | Galnt15 | ortholog_one2one | 83.2808 | ENSG00000131386 | GALNT15 | ortholog_one2one | 76.9716 | NA | NA | NA | NA | NA | NA | 78754 | 78754 | 117248 | 117248 |
| ENSMOCG00000002986 | 17.505661 | -0.5712277 | 0.3099914 | 0.0002247 | 0.0018472 | 101985291 | Cfap141 | protein_coding | 101985291 | Cfap141 | ENSMUSG00000118506 | Cfap141 | ortholog_one2one | 76.1905 | ENSG00000163263 | CFAP141 | ortholog_one2one | 72.3810 | NA | NA | NA | NA | NA | NA | 73545 | 73545 | 388701 | 388701 |
| ENSMOCG00000022644 | 19.348374 | -0.5115329 | 0.2632782 | 0.0002252 | 0.0018489 | 101980409 | processed_pseudogene | 101980409 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000004195 | 91.772821 | 0.7166909 | 0.5690487 | 0.0002268 | 0.0018600 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000008914 | 22.983393 | 0.5143557 | 0.2669592 | 0.0002312 | 0.0018898 | 101985923 | Mroh8 | protein_coding | 101985923 | Mroh8 | ENSMUSG00000074627 | Mroh8 | ortholog_one2one | 80.1527 | ENSG00000101353 | MROH8 | ortholog_one2one | 66.3168 | NA | NA | NA | NA | NA | NA | 629499 | 629499 | 140699 | 140699 |
| ENSMOCG00000013838 | 65.194306 | -0.2596714 | 0.0987508 | 0.0002353 | 0.0019171 | NA | Rnf227 | protein_coding | NA | Rnf227 | ENSMUSG00000043419 | Rnf227 | ortholog_one2one | 85.3403 | ENSG00000179859 | RNF227 | ortholog_one2one | 74.8691 | NA | NA | NA | NA | NA | NA | 80515 | 80515 | 284023 | 284023 |
| ENSMOCG00000011451 | 93.550655 | -0.3587753 | 0.1632074 | 0.0002411 | 0.0019549 | 101990697 | Car10 | protein_coding | 101990697 | Car10 | ENSMUSG00000056158 | Car10 | ortholog_one2one | 100.0000 | ENSG00000154975 | CA10 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 72605 | 72605 | 56934 | 56934 |
| ENSMOCG00000019953 | 48.090652 | 0.2566652 | 0.0974010 | 0.0002412 | 0.0019549 | 101980639 | protein_coding | 101980639 | ENSMUSG00000001674 | Ddx18 | ortholog_one2many | 89.9687 | ENSG00000088205 | DDX18 | ortholog_one2many | 85.8934 | NA | NA | NA | NA | NA | NA | 66942 | 66942 | 8886 | 8886 | ||
| ENSMOCG00000013307 | 208.790669 | -0.2508664 | 0.0943312 | 0.0002442 | 0.0019764 | NA | protein_coding | NA | ENSMUSG00000069170 | Adgrv1 | ortholog_one2many | 84.0825 | ENSG00000164199 | ADGRV1 | ortholog_one2many | 79.3511 | NA | NA | NA | NA | NA | NA | 110789 | 110789 | 84059 | 84059 | ||
| ENSMOCG00000003004 | 34.554863 | 0.3780355 | 0.1769195 | 0.0002468 | 0.0019920 | 101988888 | protein_coding | 101988888 | ENSMUSG00000007892 | Rplp1 | ortholog_many2many | 95.6140 | ENSG00000137818 | RPLP1 | ortholog_one2many | 98.2456 | ENSMUSG00000007892, ENSMUSG00000091014 | Rplp1, Gm5244 | 95.614, 86.8421 | ENSG00000137818, ENSG00000137818 | RPLP1, RPLP1 | 98.2456, 98.2456 | 56040 | 56040 | 6176 | 6176 | ||
| ENSMOCG00000009893 | 62.974808 | -0.3217272 | 0.1388586 | 0.0002470 | 0.0019923 | 101997805 | Nipal4 | protein_coding | 101997805 | Nipal4 | ENSMUSG00000020411 | Nipal4 | ortholog_one2one | 96.0591 | ENSG00000172548 | NIPAL4 | ortholog_one2one | 83.2512 | NA | NA | NA | NA | NA | NA | 214112 | 214112 | 348938 | 348938 |
| ENSMOCG00000014944 | 338.965285 | 0.2911682 | 0.1189513 | 0.0002501 | 0.0020112 | 101978966 | Exph5 | protein_coding | 101978966 | Exph5 | ENSMUSG00000034584 | Exph5 | ortholog_one2one | 73.0888 | ENSG00000110723 | EXPH5 | ortholog_one2one | 58.3161 | NA | NA | NA | NA | NA | NA | 320051 | 320051 | 23086 | 23086 |
| ENSMOCG00000017650 | 15.349310 | -0.4290209 | 0.2119150 | 0.0002510 | 0.0020164 | 101991695 | Polm | protein_coding | 101991695 | Polm | ENSMUSG00000020474 | Polm | ortholog_one2one | 77.8234 | ENSG00000122678 | POLM | ortholog_one2one | 75.7700 | NA | NA | NA | NA | NA | NA | 54125 | 54125 | 27434 | 27434 |
| ENSMOCG00000000200 | 60.035453 | 0.2640450 | 0.1026167 | 0.0002571 | 0.0020528 | NA | protein_coding | NA | ENSMUSG00000031229 | Atrx | ortholog_one2many | 96.2185 | ENSG00000085224 | ATRX | ortholog_one2many | 92.0168 | NA | NA | NA | NA | NA | NA | 22589 | 22589 | 546 | 546 | ||
| ENSMOCG00000017248 | 21.531569 | -0.3761760 | 0.1770423 | 0.0002575 | 0.0020542 | 101980323 | Pdia2 | protein_coding | 101980323 | Pdia2 | ENSMUSG00000024184 | Pdia2 | ortholog_one2one | 89.1635 | ENSG00000185615 | PDIA2 | ortholog_one2one | 79.2776 | NA | NA | NA | NA | NA | NA | 69191 | 69191 | 64714 | 64714 |
| ENSMOCG00000013103 | 60.659405 | -0.2632612 | 0.1023609 | 0.0002606 | 0.0020744 | 102000566 | Gal3st1 | protein_coding | 102000566 | Gal3st1 | ENSMUSG00000049721 | Gal3st1 | ortholog_one2one | 92.1986 | ENSG00000128242 | GAL3ST1 | ortholog_one2one | 83.4515 | NA | NA | NA | NA | NA | NA | 53897 | 53897 | 9514 | 9514 |
| ENSMOCG00000014308 | 39.171388 | -0.3008833 | 0.1263738 | 0.0002636 | 0.0020957 | 101979038 | Sspn | protein_coding | 101979038 | Sspn | ENSMUSG00000030255 | Sspn | ortholog_one2one | 87.9630 | ENSG00000123096 | SSPN | ortholog_one2one | 81.9444 | NA | NA | NA | NA | NA | NA | 16651 | 16651 | 8082 | 8082 |
| ENSMOCG00000015747 | 1139.399281 | 0.3125909 | 0.1344926 | 0.0002667 | 0.0021175 | 101995601 | Afap1 | protein_coding | 101995601 | Afap1 | ENSMUSG00000029094 | Afap1 | ortholog_one2one | 96.8579 | ENSG00000196526 | AFAP1 | ortholog_one2one | 92.3497 | NA | NA | NA | NA | NA | NA | 70292 | 70292 | 60312 | 60312 |
| ENSMOCG00000022757 | 110.137424 | -0.4070274 | 0.1995933 | 0.0002680 | 0.0021257 | 101988013 | Ldhd | protein_coding | 101988013 | Ldhd | ENSMUSG00000031958 | Ldhd | ortholog_one2one | 92.9752 | ENSG00000166816 | LDHD | ortholog_one2one | 83.8843 | NA | NA | NA | NA | NA | NA | 52815 | 52815 | 197257 | 197257 |
| ENSMOCG00000018533 | 38.347816 | -0.3993982 | 0.1953465 | 0.0002751 | 0.0021755 | 101983589 | Tent5a | protein_coding | 101983589 | Tent5a | ENSMUSG00000032265 | Tent5a | ortholog_one2one | 98.4340 | ENSG00000112773 | TENT5A | ortholog_one2one | 92.6174 | NA | NA | NA | NA | NA | NA | 212943 | 212943 | 55603 | 55603 |
| ENSMOCG00000006399 | 28.279576 | 0.3981962 | 0.1946031 | 0.0002758 | 0.0021776 | 101993682 | Mpzl3 | protein_coding | 101993682 | Mpzl3 | ENSMUSG00000070305 | Mpzl3 | ortholog_one2one | 90.3361 | ENSG00000160588 | MPZL3 | ortholog_one2one | 84.8739 | NA | NA | NA | NA | NA | NA | 319742 | 319742 | 196264 | 196264 |
| ENSMOCG00000015845 | 78.530525 | 0.3320104 | 0.1496620 | 0.0002863 | 0.0022528 | 101999148 | Abca15 | protein_coding | 101999148 | Abca15 | ENSMUSG00000054746 | Abca15 | ortholog_one2one | 77.8310 | NA | NA | NA | NA | NA | NA | NA | 320631 | 320631 | NA | NA | |||
| ENSMOCG00000006815 | 13.755491 | -0.5350406 | 0.2991523 | 0.0002862 | 0.0022528 | NA | Primpol | protein_coding | NA | Primpol | ENSMUSG00000038225 | Primpol | ortholog_one2one | 81.1460 | ENSG00000164306 | PRIMPOL | ortholog_one2one | 76.3401 | NA | NA | NA | NA | NA | NA | 408022 | 408022 | 201973 | 201973 |
| ENSMOCG00000003210 | 3470.367794 | -0.2847897 | 0.1176051 | 0.0002888 | 0.0022716 | NA | Peg10 | protein_coding | NA | Peg10 | ENSMUSG00000092035 | Peg10 | ortholog_one2one | 73.2167 | ENSG00000242265 | PEG10 | ortholog_one2one | 72.1400 | NA | NA | NA | NA | NA | NA | 170676 | 170676 | 23089 | 23089 |
| ENSMOCG00000002683 | 56.686734 | 0.2928041 | 0.1230211 | 0.0002904 | 0.0022811 | 101983112 | Rab3d | protein_coding | 101983112 | Rab3d | ENSMUSG00000019066 | Rab3d | ortholog_one2one | 98.1735 | ENSG00000105514 | RAB3D | ortholog_one2one | 94.5205 | NA | NA | NA | NA | NA | NA | 19340 | 19340 | 9545 | 9545 |
| ENSMOCG00000019320 | 795.263306 | 0.2724887 | 0.1105211 | 0.0003025 | 0.0023669 | 101988532 | protein_coding | 101988532 | ENSMUSG00000026678 | Rgs5 | ortholog_one2many | 93.3702 | ENSG00000143248 | RGS5 | ortholog_one2many | 91.7127 | NA | NA | NA | NA | NA | NA | 19737 | 19737 | 8490 | 8490 | ||
| ENSMOCG00000008496 | 75.313122 | -0.3582819 | 0.1699505 | 0.0003035 | 0.0023728 | 101992428 | B3gat2 | protein_coding | 101992428 | B3gat2 | ENSMUSG00000026156 | B3gat2 | ortholog_one2one | 98.7654 | ENSG00000112309 | B3GAT2 | ortholog_one2one | 88.5802 | NA | NA | NA | NA | NA | NA | 280645 | 280645 | 135152 | 135152 |
| ENSMOCG00000009603 | 88.587995 | -0.2917289 | 0.1233705 | 0.0003055 | 0.0023862 | 101987772 | protein_coding | 101987772 | ENSMUSG00000059810 | Rgs3 | ortholog_one2many | 90.7621 | ENSG00000138835 | RGS3 | ortholog_one2many | 85.4503 | NA | NA | NA | NA | NA | NA | 50780 | 50780 | 5998 | 5998 | ||
| ENSMOCG00000005160 | 27.444164 | 0.3626393 | 0.1737737 | 0.0003101 | 0.0024133 | 101981197 | Aspn | protein_coding | 101981197 | Aspn | ENSMUSG00000021388 | Aspn | ortholog_one2one | 96.4960 | ENSG00000106819 | ASPN | ortholog_one2one | 91.3747 | NA | NA | NA | NA | NA | NA | 66695 | 66695 | 54829 | 54829 |
| ENSMOCG00000023017 | 20.866656 | -0.3590620 | 0.1731647 | 0.0003287 | 0.0025317 | 101979337 | Slc23a4 | protein_coding | 101979337 | Slc23a4 | ENSMUSG00000029847 | Slc23a4 | ortholog_one2one | 90.8646 | NA | NA | NA | NA | NA | NA | NA | 243753 | 243753 | NA | NA | |||
| ENSMOCG00000001723 | 25.668852 | 0.4083937 | 0.2090970 | 0.0003291 | 0.0025329 | 102000416 | Atp12a | protein_coding | 102000416 | Atp12a | ENSMUSG00000022229 | Atp12a | ortholog_one2one | 95.6606 | ENSG00000075673 | ATP12A | ortholog_one2one | 87.6567 | NA | NA | NA | NA | NA | NA | 192113 | 192113 | 479 | 479 |
| ENSMOCG00000011227 | 92.354387 | -0.6484018 | 0.6308297 | 0.0003306 | 0.0025430 | 101998615 | Nwd1 | protein_coding | 101998615 | Nwd1 | ENSMUSG00000048148 | Nwd1 | ortholog_one2one | 87.0761 | ENSG00000188039 | NWD1 | ortholog_one2one | 69.9296 | NA | NA | NA | NA | NA | NA | 319555 | 319555 | 284434 | 284434 |
| ENSMOCG00000002809 | 61.728286 | -0.3087202 | 0.1372765 | 0.0003345 | 0.0025686 | 101990425 | Scube1 | protein_coding | 101990425 | Scube1 | ENSMUSG00000016763 | Scube1 | ortholog_one2one | 96.7583 | ENSG00000159307 | SCUBE1 | ortholog_one2one | 89.9804 | NA | NA | NA | NA | NA | NA | 64706 | 64706 | 80274 | 80274 |
| ENSMOCG00000014510 | 21.384045 | 0.3919877 | 0.1978227 | 0.0003347 | 0.0025686 | 101998093 | Gm1123 | protein_coding | 101998093 | Gm1123 | ENSMUSG00000044860 | Gm1123 | ortholog_one2one | 63.8462 | ENSG00000154639 | CXADR | ortholog_one2many | 24.1026 | NA | NA | NA | NA | NA | NA | 382097 | 382097 | 1525 | 1525 |
| ENSMOCG00000012408 | 47.767430 | -0.3628968 | 0.1765450 | 0.0003344 | 0.0025686 | 101997032 | Card11 | protein_coding | 101997032 | Card11 | ENSMUSG00000036526 | Card11 | ortholog_one2one | 98.2669 | ENSG00000198286 | CARD11 | ortholog_one2one | 92.8076 | NA | NA | NA | NA | NA | NA | 108723 | 108723 | 84433 | 84433 |
| ENSMOCG00000002777 | 138.959211 | -0.3637939 | 0.1784794 | 0.0003467 | 0.0026516 | 101999491 | 3830406C13Rik | protein_coding | 101999491 | 3830406C13Rik | ENSMUSG00000033111 | 3830406C13Rik | ortholog_one2one | 57.8125 | ENSG00000114405 | C3orf14 | ortholog_one2one | 74.2188 | NA | NA | NA | NA | NA | NA | 218734 | 218734 | 57415 | 57415 |
| ENSMOCG00000016612 | 53.365991 | -0.3746686 | 0.1864838 | 0.0003466 | 0.0026516 | 101981473 | Cyp4f14 | protein_coding | 101981473 | Cyp4f14 | ENSMUSG00000024292 | Cyp4f14 | ortholog_one2one | 87.0229 | ENSG00000186115 | CYP4F2 | ortholog_one2many | 66.0305 | NA | NA | NA | NA | NA | NA | 64385 | 64385 | 8529 | 8529 |
| ENSMOCG00000002606 | 76.274142 | -0.3172339 | 0.1445531 | 0.0003495 | 0.0026673 | 101982016 | processed_pseudogene | 101982016 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000001378 | 26.659700 | -0.3381792 | 0.1602118 | 0.0003532 | 0.0026861 | 101995877 | Bbof1 | protein_coding | 101995877 | Bbof1 | ENSMUSG00000057265 | Bbof1 | ortholog_one2one | 80.1444 | ENSG00000119636 | BBOF1 | ortholog_one2one | 73.4657 | NA | NA | NA | NA | NA | NA | 72873 | 72873 | 80127 | 80127 |
| ENSMOCG00000013010 | 266.055157 | -0.2731607 | 0.1139400 | 0.0003549 | 0.0026951 | 101990767 | Anln | protein_coding | 101990767 | Anln | ENSMUSG00000036777 | Anln | ortholog_one2one | 86.3758 | ENSG00000011426 | ANLN | ortholog_one2one | 81.1220 | NA | NA | NA | NA | NA | NA | 68743 | 68743 | 54443 | 54443 |
| ENSMOCG00000021477 | 20.316749 | -0.3801269 | 0.1914499 | 0.0003550 | 0.0026951 | NA | protein_coding | NA | ENSMUSG00000079235 | Ccdc13 | ortholog_one2one | 66.9421 | ENSG00000244607 | CCDC13 | ortholog_one2one | 57.4380 | NA | NA | NA | NA | NA | NA | 100502861 | 100502861 | 152206 | 152206 | ||
| ENSMOCG00000002453 | 71.213569 | -0.2643505 | 0.1087648 | 0.0003667 | 0.0027700 | 101997854 | protein_coding | 101997854 | ENSMUSG00000051727 | Kctd14 | ortholog_one2one | 82.7715 | ENSG00000151364 | KCTD14 | ortholog_one2one | 48.3146 | NA | NA | NA | NA | NA | NA | 233529 | 233529 | 65987 | 65987 | ||
| ENSMOCG00000000037 | 32.473140 | 0.3049555 | 0.1373921 | 0.0003738 | 0.0028142 | NA | Mt_tRNA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000002240 | 17.005456 | 0.6019514 | 0.4340395 | 0.0003746 | 0.0028179 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000016702 | 11.912825 | -0.5908432 | 0.4109317 | 0.0003786 | 0.0028434 | 101989967 | Ctxn3 | protein_coding | 101989967 | Ctxn3 | ENSMUSG00000069372 | Ctxn3 | ortholog_one2one | 96.2500 | ENSG00000205279 | CTXN3 | ortholog_one2one | 95.0000 | NA | NA | NA | NA | NA | NA | 629147 | 629147 | 613212 | 613212 |
| ENSMOCG00000001770 | 36.158203 | 0.4520136 | 0.2536752 | 0.0004031 | 0.0030039 | 102001074 | Slc25a34 | protein_coding | 102001074 | Slc25a34 | ENSMUSG00000040740 | Slc25a34 | ortholog_one2one | 82.0669 | ENSG00000162461 | SLC25A34 | ortholog_one2one | 76.2918 | NA | NA | NA | NA | NA | NA | 384071 | 384071 | 284723 | 284723 |
| ENSMOCG00000010143 | 88.913563 | -0.3058560 | 0.1403711 | 0.0004080 | 0.0030272 | 101995271 | Tacr3 | protein_coding | 101995271 | Tacr3 | ENSMUSG00000028172 | Tacr3 | ortholog_one2one | 94.0397 | ENSG00000169836 | TACR3 | ortholog_one2one | 89.1832 | NA | NA | NA | NA | NA | NA | 21338 | 21338 | 6870 | 6870 |
| ENSMOCG00000020990 | 41.885517 | -0.2928110 | 0.1314555 | 0.0004201 | 0.0030997 | 101995836 | N4bp3 | protein_coding | 101995836 | N4bp3 | ENSMUSG00000001053 | N4bp3 | ortholog_one2one | 94.9814 | ENSG00000145911 | N4BP3 | ortholog_one2one | 91.8216 | NA | NA | NA | NA | NA | NA | 212706 | 212706 | 23138 | 23138 |
| ENSMOCG00000016330 | 16.113446 | 0.4912835 | 0.2936414 | 0.0004285 | 0.0031508 | NA | Efcab15 | protein_coding | NA | Efcab15 | ENSMUSG00000020940 | Efcab15 | ortholog_one2one | 79.2208 | NA | NA | NA | NA | NA | NA | NA | 69441 | 69441 | NA | NA | |||
| ENSMOCG00000008239 | 62.369544 | -0.2897978 | 0.1305913 | 0.0004437 | 0.0032502 | 102000813 | Cpm | protein_coding | 102000813 | Cpm | ENSMUSG00000020183 | Cpm | ortholog_one2one | 89.1648 | ENSG00000135678 | CPM | ortholog_one2one | 83.9729 | NA | NA | NA | NA | NA | NA | 70574 | 70574 | 1368 | 1368 |
| ENSMOCG00000012488 | 21.599033 | -0.5266396 | 0.3369397 | 0.0004442 | 0.0032503 | 101986510 | Zbbx | protein_coding | 101986510 | Zbbx | ENSMUSG00000034151 | Zbbx | ortholog_one2one | 69.3166 | ENSG00000169064 | ZBBX | ortholog_one2one | 59.9721 | NA | NA | NA | NA | NA | NA | 213234 | 213234 | 79740 | 79740 |
| ENSMOCG00000011195 | 25.876792 | -0.4265042 | 0.2384291 | 0.0004442 | 0.0032503 | 101987231 | protein_coding | 101987231 | ENSMUSG00000035095 | Fam167a | ortholog_one2one | 96.4706 | ENSG00000154319 | FAM167A | ortholog_one2one | 95.2941 | NA | NA | NA | NA | NA | NA | 219148 | 219148 | 83648 | 83648 | ||
| ENSMOCG00000011400 | 27.019534 | -0.3116754 | 0.1476829 | 0.0004518 | 0.0032946 | NA | Sox21 | protein_coding | NA | Sox21 | ENSMUSG00000061517 | Sox21 | ortholog_one2one | 99.0000 | ENSG00000125285 | SOX21 | ortholog_one2one | 99.5000 | NA | NA | NA | NA | NA | NA | 223227 | 223227 | 11166 | 11166 |
| ENSMOCG00000004545 | 555.608207 | -0.2757651 | 0.1211321 | 0.0004591 | 0.0033371 | 101979710 | Dlk1 | protein_coding | 101979710 | Dlk1 | ENSMUSG00000040856 | Dlk1 | ortholog_one2one | 92.1671 | ENSG00000185559 | DLK1 | ortholog_one2one | 87.4674 | NA | NA | NA | NA | NA | NA | 13386 | 13386 | 8788 | 8788 |
| ENSMOCG00000019522 | 49.120116 | -0.2569139 | 0.1082575 | 0.0004649 | 0.0033754 | 101998722 | Arg2 | protein_coding | 101998722 | Arg2 | ENSMUSG00000021125 | Arg2 | ortholog_one2one | 90.1130 | ENSG00000081181 | ARG2 | ortholog_one2one | 86.4407 | NA | NA | NA | NA | NA | NA | 11847 | 11847 | 384 | 384 |
| ENSMOCG00000001475 | 68.423179 | 0.3064578 | 0.1461956 | 0.0004925 | 0.0035339 | 102002044 | Hao1 | protein_coding | 102002044 | Hao1 | ENSMUSG00000027261 | Hao1 | ortholog_one2one | 95.9459 | ENSG00000101323 | HAO1 | ortholog_one2one | 89.1892 | NA | NA | NA | NA | NA | NA | 15112 | 15112 | 54363 | 54363 |
| ENSMOCG00000021052 | 52.228890 | -0.2904206 | 0.1339326 | 0.0004960 | 0.0035501 | 101980038 | protein_coding | 101980038 | NA | ENSG00000213316 | LTC4S | ortholog_one2one | 90.2655 | NA | NA | NA | NA | NA | NA | NA | NA | 4056 | 4056 | |||||
| ENSMOCG00000010899 | 79.124927 | -0.2531428 | 0.1073415 | 0.0005065 | 0.0036205 | 101981848 | Lrrc75b | protein_coding | 101981848 | Lrrc75b | ENSMUSG00000046807 | Lrrc75b | ortholog_one2one | 91.9355 | ENSG00000178026 | LRRC75B | ortholog_one2one | 83.8710 | NA | NA | NA | NA | NA | NA | 192734 | 192734 | 388886 | 388886 |
| ENSMOCG00000008456 | 49.818922 | 0.3097438 | 0.1508263 | 0.0005258 | 0.0037344 | 101999950 | Fezf2 | protein_coding | 101999950 | Fezf2 | ENSMUSG00000021743 | Fezf2 | ortholog_one2one | 97.8022 | ENSG00000153266 | FEZF2 | ortholog_one2one | 96.0440 | NA | NA | NA | NA | NA | NA | 54713 | 54713 | 55079 | 55079 |
| ENSMOCG00000015792 | 29.151070 | -0.4054745 | 0.2315860 | 0.0005362 | 0.0037889 | 101995582 | Rsph4a | protein_coding | 101995582 | Rsph4a | ENSMUSG00000039552 | Rsph4a | ortholog_one2one | 78.7879 | ENSG00000111834 | RSPH4A | ortholog_one2one | 70.5234 | NA | NA | NA | NA | NA | NA | 212892 | 212892 | 345895 | 345895 |
| ENSMOCG00000011558 | 15.318551 | -0.4406351 | 0.2656043 | 0.0005522 | 0.0038868 | NA | protein_coding | NA | ENSMUSG00000060803 | Gstp1 | ortholog_many2many | 89.3720 | ENSG00000084207 | GSTP1 | ortholog_one2many | 82.6087 | ENSMUSG00000060803, ENSMUSG00000038155 | Gstp1, Gstp2 | 89.372, 87.9227 | ENSG00000084207, ENSG00000084207 | GSTP1, GSTP1 | 82.6087, 82.6087 | 14870 | 14870 | 2950 | 2950 | ||
| ENSMOCG00000020923 | 25.772262 | 0.3459924 | 0.1826886 | 0.0005557 | 0.0039050 | 101988183 | Fancd2 | protein_coding | 101988183 | Fancd2 | ENSMUSG00000034023 | Fancd2 | ortholog_one2one | 87.4656 | ENSG00000144554 | FANCD2 | ortholog_one2one | 75.6887 | NA | NA | NA | NA | NA | NA | 211651 | 211651 | 2177 | 2177 |
| ENSMOCG00000019802 | 30.329937 | 0.3425983 | 0.1804836 | 0.0005644 | 0.0039562 | 101983864 | Ptpn7 | protein_coding | 101983864 | Ptpn7 | ENSMUSG00000031506 | Ptpn7 | ortholog_one2one | 92.7577 | ENSG00000143851 | PTPN7 | ortholog_one2one | 91.9220 | NA | NA | NA | NA | NA | NA | 320139 | 320139 | 5778 | 5778 |
| ENSMOCG00000019904 | 14.877844 | -0.4042656 | 0.2340238 | 0.0005685 | 0.0039744 | 101984071 | Aloxe3 | protein_coding | 101984071 | Aloxe3 | ENSMUSG00000020892 | Aloxe3 | ortholog_one2one | 94.2335 | ENSG00000179148 | ALOXE3 | ortholog_one2one | 88.7482 | NA | NA | NA | NA | NA | NA | 23801 | 23801 | 59344 | 59344 |
| ENSMOCG00000020554 | 16.412909 | 0.4967753 | 0.3347815 | 0.0005822 | 0.0040539 | 101979981 | Lix1 | protein_coding | 101979981 | Lix1 | ENSMUSG00000047786 | Lix1 | ortholog_one2one | 97.8723 | ENSG00000145721 | LIX1 | ortholog_one2one | 93.6170 | NA | NA | NA | NA | NA | NA | 66643 | 66643 | 167410 | 167410 |
| ENSMOCG00000004801 | 24.512212 | -0.3981034 | 0.2305546 | 0.0005882 | 0.0040819 | 101999438 | Cfap90 | protein_coding | 101999438 | Cfap90 | ENSMUSG00000021534 | Cfap90 | ortholog_one2one | 83.3333 | ENSG00000215217 | CFAP90 | ortholog_one2one | 69.0476 | NA | NA | NA | NA | NA | NA | 69315 | 69315 | 134121 | 134121 |
| ENSMOCG00000021121 | 34.858817 | 0.3324399 | 0.1740289 | 0.0005951 | 0.0041236 | 101980000 | Parp14 | protein_coding | 101980000 | Parp14 | ENSMUSG00000034422 | Parp14 | ortholog_one2one | 71.2433 | ENSG00000173193 | PARP14 | ortholog_one2one | 61.7086 | NA | NA | NA | NA | NA | NA | 547253 | 547253 | 54625 | 54625 |
| ENSMOCG00000000538 | 86.021106 | -0.2640369 | 0.1189983 | 0.0006093 | 0.0042080 | 102002920 | Cdk20 | protein_coding | 102002920 | Cdk20 | ENSMUSG00000021483 | Cdk20 | ortholog_one2one | 98.5549 | ENSG00000156345 | CDK20 | ortholog_one2one | 93.3526 | NA | NA | NA | NA | NA | NA | 105278 | 105278 | 23552 | 23552 |
| ENSMOCG00000014117 | 39.635616 | 0.2932455 | 0.1424191 | 0.0006175 | 0.0042431 | 101994696 | Ddc | protein_coding | 101994696 | Ddc | ENSMUSG00000020182 | Ddc | ortholog_one2one | 95.4167 | ENSG00000132437 | DDC | ortholog_one2one | 90.0000 | NA | NA | NA | NA | NA | NA | 13195 | 13195 | 1644 | 1644 |
| ENSMOCG00000011210 | 66.016581 | -0.2776119 | 0.1302972 | 0.0006290 | 0.0043090 | 101984296 | Rac2 | protein_coding | 101984296 | Rac2 | ENSMUSG00000033220 | Rac2 | ortholog_one2one | 100.0000 | ENSG00000128340 | RAC2 | ortholog_one2one | 98.9583 | NA | NA | NA | NA | NA | NA | 19354 | 19354 | 5880 | 5880 |
| ENSMOCG00000019570 | 31.523933 | -0.3299954 | 0.1742149 | 0.0006300 | 0.0043114 | 101979119 | Pawr | protein_coding | 101979119 | Pawr | ENSMUSG00000035873 | Pawr | ortholog_one2one | 86.8263 | ENSG00000177425 | PAWR | ortholog_one2one | 78.1437 | NA | NA | NA | NA | NA | NA | 114774 | 114774 | 5074 | 5074 |
| ENSMOCG00000015835 | 50.066738 | -0.2612744 | 0.1178544 | 0.0006342 | 0.0043358 | NA | Sowahc | protein_coding | NA | Sowahc | ENSMUSG00000098188 | Sowahc | ortholog_one2one | 84.4660 | ENSG00000198142 | SOWAHC | ortholog_one2one | 74.1748 | NA | NA | NA | NA | NA | NA | 268301 | 268301 | 65124 | 65124 |
| ENSMOCG00000000186 | 39.851399 | 0.2663130 | 0.1221954 | 0.0006477 | 0.0044130 | 101991605 | Parp3 | protein_coding | 101991605 | Parp3 | ENSMUSG00000023249 | Parp3 | ortholog_one2one | 87.6426 | ENSG00000041880 | PARP3 | ortholog_one2one | 81.7490 | NA | NA | NA | NA | NA | NA | 235587 | 235587 | 10039 | 10039 |
| ENSMOCG00000020363 | 66.246383 | -0.4981098 | 0.3551111 | 0.0006490 | 0.0044139 | NA | Cfap43 | protein_coding | NA | Cfap43 | ENSMUSG00000044948 | Cfap43 | ortholog_one2one | 81.4039 | ENSG00000197748 | CFAP43 | ortholog_one2one | 74.6305 | NA | NA | NA | NA | NA | NA | 100048534 | 100048534 | 80217 | 80217 |
| ENSMOCG00000003549 | 305.892007 | -0.2636648 | 0.1202012 | 0.0006488 | 0.0044139 | 101990216 | Itih3 | protein_coding | 101990216 | Itih3 | ENSMUSG00000006522 | Itih3 | ortholog_one2one | 89.0011 | ENSG00000162267 | ITIH3 | ortholog_one2one | 82.8283 | NA | NA | NA | NA | NA | NA | 16426 | 16426 | 3699 | 3699 |
| ENSMOCG00000000234 | 22.160655 | -0.4397079 | 0.2812550 | 0.0006724 | 0.0045411 | NA | Arl5c | protein_coding | NA | Arl5c | ENSMUSG00000038352 | Arl5c | ortholog_one2one | 90.4192 | ENSG00000141748 | ARL5C | ortholog_one2one | 77.2455 | NA | NA | NA | NA | NA | NA | 217151 | 217151 | 390790 | 390790 |
| ENSMOCG00000015819 | 25.965641 | -0.3621925 | 0.2059465 | 0.0006761 | 0.0045586 | 102001806 | Fmod | protein_coding | 102001806 | Fmod | ENSMUSG00000041559 | Fmod | ortholog_one2one | 96.0212 | ENSG00000122176 | FMOD | ortholog_one2one | 90.9814 | NA | NA | NA | NA | NA | NA | 14264 | 14264 | 2331 | 2331 |
| ENSMOCG00000014926 | 60.292131 | -0.3416414 | 0.1876512 | 0.0006788 | 0.0045750 | 101993852 | Nat8f1 | protein_coding | 101993852 | Nat8f1 | ENSMUSG00000057103 | Nat8f1 | ortholog_one2one | 78.4483 | ENSG00000144035 | NAT8 | ortholog_many2many | 59.0517 | ENSMUSG00000057103, ENSMUSG00000057103 | Nat8f1, Nat8f1 | 78.4483, 78.4483 | ENSG00000144035, ENSG00000204872 | NAT8, NAT8B | 59.0517, 57.7586 | 66116 | 66116 | 9027 | 9027 |
| ENSMOCG00000015635 | 48.103450 | 0.3897298 | 0.2319124 | 0.0006819 | 0.0045923 | 101992327 | Col6a1 | protein_coding | 101992327 | Col6a1 | ENSMUSG00000001119 | Col6a1 | ortholog_one2one | 97.2710 | ENSG00000142156 | COL6A1 | ortholog_one2one | 90.2534 | NA | NA | NA | NA | NA | NA | 12833 | 12833 | 1291 | 1291 |
| ENSMOCG00000013318 | 19490.819617 | -0.2548547 | 0.1155593 | 0.0007081 | 0.0047411 | 101992593 | Mbp | protein_coding | 101992593 | Mbp | ENSMUSG00000041607 | Mbp | ortholog_one2one | 94.8000 | ENSG00000197971 | MBP | ortholog_one2one | 87.6000 | NA | NA | NA | NA | NA | NA | 17196 | 17196 | 4155 | 4155 |
| ENSMOCG00000001681 | 54.269451 | 0.2917757 | 0.1456178 | 0.0007104 | 0.0047493 | 102002384 | Mid1 | protein_coding | 102002384 | Mid1 | ENSMUSG00000035299 | Mid1 | ortholog_one2one | 95.2024 | ENSG00000101871 | MID1 | ortholog_one2one | 98.9505 | NA | NA | NA | NA | NA | NA | 17318 | 17318 | 4281 | 4281 |
| ENSMOCG00000001650 | 75.923870 | -0.4405713 | 0.2894292 | 0.0007240 | 0.0048280 | NA | Wdr27 | protein_coding | NA | Wdr27 | ENSMUSG00000046991 | Wdr27 | ortholog_one2one | 79.3854 | ENSG00000184465 | WDR27 | ortholog_one2one | 61.5877 | NA | NA | NA | NA | NA | NA | 71682 | 71682 | 253769 | 253769 |
| ENSMOCG00000010850 | 104.913741 | -0.2596807 | 0.1203822 | 0.0007417 | 0.0049188 | 102001336 | Tmem63a | protein_coding | 102001336 | Tmem63a | ENSMUSG00000026519 | Tmem63a | ortholog_one2one | 93.6567 | ENSG00000196187 | TMEM63A | ortholog_one2one | 86.6915 | NA | NA | NA | NA | NA | NA | 208795 | 208795 | 9725 | 9725 |
| ENSMOCG00000000821 | 42.781076 | -0.3242109 | 0.1764464 | 0.0007514 | 0.0049713 | 101995452 | Emb | protein_coding | 101995452 | Emb | ENSMUSG00000021728 | Emb | ortholog_one2one | 73.9521 | ENSG00000170571 | EMB | ortholog_one2one | 67.9641 | NA | NA | NA | NA | NA | NA | 13723 | 13723 | 133418 | 133418 |
| ENSMOCG00000008195 | 39.304656 | -0.2542123 | 0.1165777 | 0.0007554 | 0.0049928 | NA | protein_coding | NA | ENSMUSG00000002105 | Slc39a13 | ortholog_one2many | 88.5714 | ENSG00000165915 | SLC39A13 | ortholog_one2many | 86.4286 | NA | NA | NA | NA | NA | NA | 68427 | 68427 | 91252 | 91252 | ||
| ENSMOCG00000001188 | 32.110156 | 0.2837139 | 0.1410724 | 0.0007646 | 0.0050383 | 101996352 | Rbm46 | protein_coding | 101996352 | Rbm46 | ENSMUSG00000033882 | Rbm46 | ortholog_one2one | 97.9362 | ENSG00000151962 | RBM46 | ortholog_one2one | 97.5610 | NA | NA | NA | NA | NA | NA | 633285 | 633285 | 166863 | 166863 |
| ENSMOCG00000017730 | 60.520923 | -0.2834150 | 0.1412690 | 0.0007756 | 0.0050929 | 101980724 | Pnoc | protein_coding | 101980724 | Pnoc | ENSMUSG00000045731 | Pnoc | ortholog_one2one | 85.7143 | ENSG00000168081 | PNOC | ortholog_one2one | 78.2857 | NA | NA | NA | NA | NA | NA | 18155 | 18155 | 5368 | 5368 |
| ENSMOCG00000021098 | 40.153222 | 0.2682659 | 0.1285577 | 0.0007781 | 0.0051047 | 101984028 | Car13 | protein_coding | 101984028 | Car13 | ENSMUSG00000027555 | Car13 | ortholog_one2one | 96.1832 | ENSG00000185015 | CA13 | ortholog_one2one | 90.4580 | NA | NA | NA | NA | NA | NA | 71934 | 71934 | 377677 | 377677 |
| ENSMOCG00000011792 | 65.407660 | -0.2965878 | 0.1534579 | 0.0007896 | 0.0051640 | 101987442 | protein_coding | 101987442 | ENSMUSG00000015247 | Nipsnap3b | ortholog_one2many | 90.6883 | ENSG00000136783 | NIPSNAP3A | ortholog_one2many | 83.4008 | NA | NA | NA | NA | NA | NA | 66536 | 66536 | 25934 | 25934 | ||
| ENSMOCG00000004827 | 28.061458 | -0.4438346 | 0.3032870 | 0.0007910 | 0.0051640 | 101994875 | Dnai3 | protein_coding | 101994875 | Dnai3 | ENSMUSG00000043020 | Dnai3 | ortholog_one2one | 86.1920 | ENSG00000162643 | DNAI3 | ortholog_one2one | 78.8565 | NA | NA | NA | NA | NA | NA | 242253 | 242253 | 126820 | 126820 |
| ENSMOCG00000009339 | 26.406695 | -0.3670992 | 0.2205062 | 0.0008064 | 0.0052368 | 101983631 | Chodl | protein_coding | 101983631 | Chodl | ENSMUSG00000022860 | Chodl | ortholog_one2one | 87.5458 | ENSG00000154645 | CHODL | ortholog_one2one | 93.7729 | NA | NA | NA | NA | NA | NA | 246048 | 246048 | 140578 | 140578 |
| ENSMOCG00000015386 | 406.264852 | -0.3021461 | 0.1596503 | 0.0008149 | 0.0052810 | 101999404 | Gabrq | protein_coding | 101999404 | Gabrq | ENSMUSG00000031344 | Gabrq | ortholog_one2one | 89.9687 | ENSG00000268089 | GABRQ | ortholog_one2one | 77.1160 | NA | NA | NA | NA | NA | NA | 57249 | 57249 | 55879 | 55879 |
| ENSMOCG00000017685 | 137.570548 | -0.2947051 | 0.1540747 | 0.0008411 | 0.0054271 | 102000436 | Heph | protein_coding | 102000436 | Heph | ENSMUSG00000031209 | Heph | ortholog_one2one | 90.0691 | ENSG00000089472 | HEPH | ortholog_one2one | 85.4922 | NA | NA | NA | NA | NA | NA | 15203 | 15203 | 9843 | 9843 |
| ENSMOCG00000013522 | 17.257797 | 0.4014622 | 0.2605353 | 0.0008571 | 0.0055118 | 101992319 | protein_coding | 101992319 | ENSMUSG00000028182 | Lrriq3 | ortholog_one2one | 81.0651 | ENSG00000162620 | LRRIQ3 | ortholog_one2one | 73.9645 | NA | NA | NA | NA | NA | NA | 74435 | 74435 | 127255 | 127255 | ||
| ENSMOCG00000003804 | 17.032548 | 0.3337586 | 0.1929900 | 0.0008825 | 0.0056422 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000003146 | 59.702875 | 0.2978971 | 0.1589106 | 0.0008842 | 0.0056504 | NA | Nmrk2 | protein_coding | NA | Nmrk2 | ENSMUSG00000004939 | Nmrk2 | ortholog_one2one | 86.6667 | ENSG00000077009 | NMRK2 | ortholog_one2one | 85.1282 | NA | NA | NA | NA | NA | NA | 69564 | 69564 | 27231 | 27231 |
| ENSMOCG00000011420 | 54.025410 | 0.2590778 | 0.1245403 | 0.0008865 | 0.0056625 | 101988579 | Tnfaip2 | protein_coding | 101988579 | Tnfaip2 | ENSMUSG00000021281 | Tnfaip2 | ortholog_one2one | 83.5971 | ENSG00000185215 | TNFAIP2 | ortholog_one2one | 68.4892 | NA | NA | NA | NA | NA | NA | 21928 | 21928 | 7127 | 7127 |
| ENSMOCG00000007903 | 21.121655 | -0.3075027 | 0.1697629 | 0.0009233 | 0.0058443 | 101996016 | Ier3 | protein_coding | 101996016 | Ier3 | ENSMUSG00000003541 | Ier3 | ortholog_one2one | 86.2500 | ENSG00000137331 | IER3 | ortholog_one2one | 71.2500 | NA | NA | NA | NA | NA | NA | 15937 | 15937 | 8870 | 8870 |
| ENSMOCG00000007659 | 31.009117 | -0.3084041 | 0.1709116 | 0.0009293 | 0.0058684 | 101991299 | Ppil6 | protein_coding | 101991299 | Ppil6 | ENSMUSG00000078451 | Ppil6 | ortholog_one2one | 88.1789 | ENSG00000185250 | PPIL6 | ortholog_one2one | 74.4409 | NA | NA | NA | NA | NA | NA | 73075 | 73075 | 285755 | 285755 |
| ENSMOCG00000014815 | 53.815078 | 0.2779775 | 0.1425486 | 0.0009327 | 0.0058811 | 101991125 | Fmn1 | protein_coding | 101991125 | Fmn1 | ENSMUSG00000044042 | Fmn1 | ortholog_one2one | 84.6690 | ENSG00000248905 | FMN1 | ortholog_one2one | 74.0070 | NA | NA | NA | NA | NA | NA | 14260 | 14260 | 342184 | 342184 |
| ENSMOCG00000011502 | 809.161346 | 0.2509553 | 0.1193480 | 0.0009382 | 0.0059047 | 101998430 | Ophn1 | protein_coding | 101998430 | Ophn1 | ENSMUSG00000031214 | Ophn1 | ortholog_one2one | 95.0125 | ENSG00000079482 | OPHN1 | ortholog_one2one | 93.8903 | NA | NA | NA | NA | NA | NA | 94190 | 94190 | 4983 | 4983 |
| ENSMOCG00000020262 | 23.185186 | -0.2946491 | 0.1584182 | 0.0009433 | 0.0059315 | 101985114 | Nuak2 | protein_coding | 101985114 | Nuak2 | ENSMUSG00000009772 | Nuak2 | ortholog_one2one | 94.4984 | ENSG00000163545 | NUAK2 | ortholog_one2one | 87.2168 | NA | NA | NA | NA | NA | NA | 74137 | 74137 | 81788 | 81788 |
| ENSMOCG00000009503 | 41.422876 | 0.2565734 | 0.1241460 | 0.0009432 | 0.0059315 | 101985539 | Tpbgl | protein_coding | 101985539 | Tpbgl | ENSMUSG00000096606 | Tpbgl | ortholog_one2one | 92.7083 | ENSG00000261594 | TPBGL | ortholog_one2one | 86.4583 | NA | NA | NA | NA | NA | NA | 100503386 | 100503386 | 100507050 | 100507050 |
| ENSMOCG00000021101 | 12.603763 | 0.4725388 | 0.4216638 | 0.0009596 | 0.0060198 | 102000827 | Spaca1 | protein_coding | 102000827 | Spaca1 | ENSMUSG00000028264 | Spaca1 | ortholog_one2one | 82.3333 | ENSG00000118434 | SPACA1 | ortholog_one2one | 68.6667 | NA | NA | NA | NA | NA | NA | 67652 | 67652 | 81833 | 81833 |
| ENSMOCG00000004168 | 26.285666 | -0.3114119 | 0.1755038 | 0.0009646 | 0.0060453 | 101980793 | Ccdc88b | protein_coding | 101980793 | Ccdc88b | ENSMUSG00000047810 | Ccdc88b | ortholog_one2one | 87.3555 | ENSG00000168071 | CCDC88B | ortholog_one2one | 78.9259 | NA | NA | NA | NA | NA | NA | 78317 | 78317 | 283234 | 283234 |
| ENSMOCG00000002323 | 75.488928 | -0.2514070 | 0.1210023 | 0.0009851 | 0.0061535 | 101995053 | Aff2 | protein_coding | 101995053 | Aff2 | ENSMUSG00000031189 | Aff2 | ortholog_one2one | 91.9685 | ENSG00000155966 | AFF2 | ortholog_one2one | 87.9528 | NA | NA | NA | NA | NA | NA | 14266 | 14266 | 2334 | 2334 |
| ENSMOCG00000012471 | 14.795513 | -0.3642400 | 0.2329734 | 0.0010180 | 0.0063288 | 101997576 | L3mbtl1 | protein_coding | 101997576 | L3mbtl1 | ENSMUSG00000035576 | L3mbtl1 | ortholog_one2one | 87.2727 | ENSG00000185513 | L3MBTL1 | ortholog_one2one | 79.3939 | NA | NA | NA | NA | NA | NA | 241764 | 241764 | 26013 | 26013 |
| ENSMOCG00000010871 | 24.965365 | -0.3469799 | 0.2144796 | 0.0010184 | 0.0063288 | 101987271 | Minar1 | protein_coding | 101987271 | Minar1 | ENSMUSG00000039313 | Minar1 | ortholog_one2one | 95.8560 | ENSG00000169330 | MINAR1 | ortholog_one2one | 89.9673 | NA | NA | NA | NA | NA | NA | 209743 | 209743 | 23251 | 23251 |
| ENSMOCG00000005623 | 37.933099 | -0.3868554 | 0.2608141 | 0.0010429 | 0.0064573 | NA | protein_coding | NA | ENSMUSG00000028234 | Rps20 | ortholog_one2many | 97.4790 | ENSG00000008988 | RPS20 | ortholog_one2many | 97.4790 | NA | NA | NA | NA | NA | NA | 67427 | 67427 | 6224 | 6224 | ||
| ENSMOCG00000002297 | 19.742990 | 0.3690462 | 0.2411406 | 0.0010569 | 0.0065106 | 101981934 | Col9a1 | protein_coding | 101981934 | Col9a1 | ENSMUSG00000026147 | Col9a1 | ortholog_one2one | 92.6914 | ENSG00000112280 | COL9A1 | ortholog_one2one | 89.5592 | NA | NA | NA | NA | NA | NA | 12839 | 12839 | 1297 | 1297 |
| ENSMOCG00000022524 | 12.150207 | 0.4206735 | 0.3083037 | 0.0010585 | 0.0065176 | 101980216 | Rgs18 | protein_coding | 101980216 | Rgs18 | ENSMUSG00000026357 | Rgs18 | ortholog_one2one | 90.6383 | ENSG00000150681 | RGS18 | ortholog_one2one | 83.8298 | NA | NA | NA | NA | NA | NA | 64214 | 64214 | 64407 | 64407 |
| ENSMOCG00000012607 | 15.618552 | 0.3965622 | 0.2752046 | 0.0010677 | 0.0065678 | 101995807 | 2310030G06Rik | protein_coding | 101995807 | 2310030G06Rik | ENSMUSG00000032062 | 2310030G06Rik | ortholog_one2one | 71.3287 | ENSG00000149300 | C11orf52 | ortholog_one2one | 53.1469 | NA | NA | NA | NA | NA | NA | 66952 | 66952 | 91894 | 91894 |
| ENSMOCG00000017017 | 12.620978 | 0.3755598 | 0.2516387 | 0.0010956 | 0.0067055 | 101996146 | Ticrr | protein_coding | 101996146 | Ticrr | ENSMUSG00000046591 | Ticrr | ortholog_one2one | 81.0492 | ENSG00000140534 | TICRR | ortholog_one2many | 69.5931 | NA | NA | NA | NA | NA | NA | 77011 | 77011 | 90381 | 90381 |
| ENSMOCG00000002759 | 38.745079 | -0.3384658 | 0.2104546 | 0.0011037 | 0.0067428 | 101989957 | Vwa5b1 | protein_coding | 101989957 | Vwa5b1 | ENSMUSG00000028753 | Vwa5b1 | ortholog_one2one | 81.7063 | ENSG00000158816 | VWA5B1 | ortholog_one2one | 75.1436 | NA | NA | NA | NA | NA | NA | 75718 | 75718 | 127731 | 127731 |
| ENSMOCG00000018638 | 22.953406 | -0.3717903 | 0.2498320 | 0.0011307 | 0.0068809 | 101981750 | Crh | protein_coding | 101981750 | Crh | ENSMUSG00000049796 | Crh | ortholog_one2one | 90.9091 | ENSG00000147571 | CRH | ortholog_one2one | 80.2139 | NA | NA | NA | NA | NA | NA | 12918 | 12918 | 1392 | 1392 |
| ENSMOCG00000015998 | 29.044126 | -0.3061463 | 0.1783332 | 0.0011434 | 0.0069470 | 101993239 | Itgb7 | protein_coding | 101993239 | Itgb7 | ENSMUSG00000001281 | Itgb7 | ortholog_one2one | 90.3630 | ENSG00000139626 | ITGB7 | ortholog_one2one | 85.7322 | NA | NA | NA | NA | NA | NA | 16421 | 16421 | 3695 | 3695 |
| ENSMOCG00000004567 | 23.945480 | -0.2993759 | 0.1713512 | 0.0011430 | 0.0069470 | 101986265 | Comp | protein_coding | 101986265 | Comp | ENSMUSG00000031849 | Comp | ortholog_one2one | 94.1722 | ENSG00000105664 | COMP | ortholog_one2one | 89.5364 | NA | NA | NA | NA | NA | NA | 12845 | 12845 | 1311 | 1311 |
| ENSMOCG00000013923 | 19.921691 | -0.3469167 | 0.2226816 | 0.0011542 | 0.0070032 | 101999259 | Slitrk6 | protein_coding | 101999259 | Slitrk6 | ENSMUSG00000045871 | Slitrk6 | ortholog_one2one | 92.6103 | ENSG00000184564 | SLITRK6 | ortholog_one2one | 89.5113 | NA | NA | NA | NA | NA | NA | 239250 | 239250 | 84189 | 84189 |
| ENSMOCG00000002507 | 139.749045 | -0.2710169 | 0.1437363 | 0.0011596 | 0.0070259 | 101992821 | Matn2 | protein_coding | 101992821 | Matn2 | ENSMUSG00000022324 | Matn2 | ortholog_one2one | 90.2256 | ENSG00000132561 | MATN2 | ortholog_one2one | 88.0773 | NA | NA | NA | NA | NA | NA | 17181 | 17181 | 4147 | 4147 |
| ENSMOCG00000020959 | 51.312722 | -0.4340890 | 0.3549533 | 0.0011693 | 0.0070753 | 101984671 | Slc17a6 | protein_coding | 101984671 | Slc17a6 | ENSMUSG00000030500 | Slc17a6 | ortholog_one2one | 98.7972 | ENSG00000091664 | SLC17A6 | ortholog_one2one | 97.5945 | NA | NA | NA | NA | NA | NA | 140919 | 140919 | 57084 | 57084 |
| ENSMOCG00000001608 | 29.783230 | 0.3247376 | 0.2005826 | 0.0011976 | 0.0072205 | 102001532 | processed_pseudogene | 102001532 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000018773 | 47.340274 | -0.2854779 | 0.1594134 | 0.0012009 | 0.0072369 | NA | Scube3 | protein_coding | NA | Scube3 | ENSMUSG00000038677 | Scube3 | ortholog_one2one | 96.3415 | ENSG00000146197 | SCUBE3 | ortholog_one2one | 95.6301 | NA | NA | NA | NA | NA | NA | 268935 | 268935 | 222663 | 222663 |
| ENSMOCG00000013268 | 23.691386 | -0.2821080 | 0.1563545 | 0.0012108 | 0.0072866 | 101998771 | Tpcn2 | protein_coding | 101998771 | Tpcn2 | ENSMUSG00000048677 | Tpcn2 | ortholog_one2one | 87.3469 | ENSG00000162341 | TPCN2 | ortholog_one2one | 75.3742 | NA | NA | NA | NA | NA | NA | 233979 | 233979 | 219931 | 219931 |
| ENSMOCG00000019454 | 61.808340 | -0.2620437 | 0.1380998 | 0.0012602 | 0.0075228 | 101979243 | Rhou | protein_coding | 101979243 | Rhou | ENSMUSG00000039960 | Rhou | ortholog_one2one | 82.7586 | ENSG00000116574 | RHOU | ortholog_one2one | 79.6935 | NA | NA | NA | NA | NA | NA | 69581 | 69581 | 58480 | 58480 |
| ENSMOCG00000006632 | 266.061278 | -0.4327523 | 0.4018401 | 0.0012861 | 0.0076499 | 101987257 | Mgst1 | protein_coding | 101987257 | Mgst1 | ENSMUSG00000008540 | Mgst1 | ortholog_one2one | 89.6774 | ENSG00000008394 | MGST1 | ortholog_one2one | 85.1613 | NA | NA | NA | NA | NA | NA | 56615 | 56615 | 4257 | 4257 |
| ENSMOCG00000018644 | 60.369792 | -0.2616771 | 0.1394359 | 0.0013214 | 0.0078005 | 101989530 | Tmem266 | protein_coding | 101989530 | Tmem266 | ENSMUSG00000032313 | Tmem266 | ortholog_one2one | 92.7374 | ENSG00000169758 | TMEM266 | ortholog_one2one | 86.7784 | NA | NA | NA | NA | NA | NA | 244886 | 244886 | 123591 | 123591 |
| ENSMOCG00000005883 | 1858.682708 | 0.2590072 | 0.1369450 | 0.0013253 | 0.0078065 | 101998584 | Dkk3 | protein_coding | 101998584 | Dkk3 | ENSMUSG00000030772 | Dkk3 | ortholog_one2one | 86.7816 | ENSG00000050165 | DKK3 | ortholog_one2one | 84.4828 | NA | NA | NA | NA | NA | NA | 50781 | 50781 | 27122 | 27122 |
| ENSMOCG00000004054 | 21.919549 | -0.2782967 | 0.1565809 | 0.0013340 | 0.0078545 | 101999320 | protein_coding | 101999320 | NA | ENSG00000213903 | LTB4R | ortholog_one2one | 77.1676 | NA | NA | NA | NA | NA | NA | NA | NA | 1241 | 1241 | |||||
| ENSMOCG00000006742 | 16.417758 | -0.3764932 | 0.2732575 | 0.0013498 | 0.0079295 | 101995690 | Pth2r | protein_coding | 101995690 | Pth2r | ENSMUSG00000025946 | Pth2r | ortholog_one2one | 90.4762 | ENSG00000144407 | PTH2R | ortholog_one2one | 83.3333 | NA | NA | NA | NA | NA | NA | 213527 | 213527 | 5746 | 5746 |
| ENSMOCG00000001684 | 32.939774 | -0.3137714 | 0.1959742 | 0.0013585 | 0.0079631 | 102002010 | Cubn | protein_coding | 102002010 | Cubn | ENSMUSG00000026726 | Cubn | ortholog_one2one | 80.5249 | ENSG00000107611 | CUBN | ortholog_one2one | 69.3646 | NA | NA | NA | NA | NA | NA | 65969 | 65969 | 8029 | 8029 |
| ENSMOCG00000019951 | 17.451389 | -0.3047086 | 0.1867623 | 0.0013810 | 0.0080724 | NA | Nkain1 | protein_coding | NA | Nkain1 | ENSMUSG00000078532 | Nkain1 | ortholog_one2one | 80.7882 | ENSG00000084628 | NKAIN1 | ortholog_one2one | 80.7882 | NA | NA | NA | NA | NA | NA | 67149 | 67149 | 79570 | 79570 |
| ENSMOCG00000005617 | 180.552825 | -0.2626792 | 0.1420528 | 0.0013808 | 0.0080724 | 101984831 | protein_coding | 101984831 | ENSMUSG00000090877 | Hspa1b | ortholog_one2many | 98.2839 | ENSG00000204388 | HSPA1B | ortholog_one2many | 95.6318 | ENSMUSG00000090877, ENSMUSG00000091971, ENSMUSG00000090877, ENSMUSG00000091971 | Hspa1b, Hspa1a, Hspa1b, Hspa1a | 98.2839, 98.2839, 98.2839, 98.2839 | ENSG00000204388, ENSG00000204388, ENSG00000204389, ENSG00000204389 | HSPA1B, HSPA1B, HSPA1A, HSPA1A | 95.6318, 95.6318, 95.6318, 95.6318 | 15511 | 15511 | 3304 | 3304 | ||
| ENSMOCG00000018565 | 25.936390 | -0.2595974 | 0.1391799 | 0.0013879 | 0.0081038 | 102000782 | Itgae | protein_coding | 102000782 | Itgae | ENSMUSG00000005947 | Itgae | ortholog_one2one | 82.2012 | ENSG00000083457 | ITGAE | ortholog_one2one | 71.5391 | NA | NA | NA | NA | NA | NA | 16407 | 16407 | 3682 | 3682 |
| ENSMOCG00000016963 | 21.335634 | 0.2719005 | 0.1517574 | 0.0013920 | 0.0081204 | 101982431 | Olfm4 | protein_coding | 101982431 | Olfm4 | ENSMUSG00000022026 | Olfm4 | ortholog_one2one | 83.8403 | ENSG00000102837 | OLFM4 | ortholog_one2one | 68.0608 | NA | NA | NA | NA | NA | NA | 380924 | 380924 | 10562 | 10562 |
| ENSMOCG00000019639 | 46.631251 | -0.2719365 | 0.1519194 | 0.0013961 | 0.0081337 | 101999180 | Cdh23 | protein_coding | 101999180 | Cdh23 | ENSMUSG00000012819 | Cdh23 | ortholog_one2one | 96.8282 | ENSG00000107736 | CDH23 | ortholog_one2one | 94.1352 | NA | NA | NA | NA | NA | NA | 22295 | 22295 | 64072 | 64072 |
| ENSMOCG00000017815 | 29.652073 | -0.2821668 | 0.1630641 | 0.0014075 | 0.0081892 | 101997169 | Fbp2 | protein_coding | 101997169 | Fbp2 | ENSMUSG00000021456 | Fbp2 | ortholog_one2one | 97.0588 | ENSG00000130957 | FBP2 | ortholog_one2one | 95.2941 | NA | NA | NA | NA | NA | NA | 14120 | 14120 | 8789 | 8789 |
| ENSMOCG00000019742 | 13.956974 | -0.3711635 | 0.2737383 | 0.0014503 | 0.0083981 | 101993861 | Cpa2 | protein_coding | 101993861 | Cpa2 | ENSMUSG00000071553 | Cpa2 | ortholog_one2one | 84.9765 | ENSG00000158516 | CPA2 | ortholog_one2one | 84.2723 | NA | NA | NA | NA | NA | NA | 232680 | 232680 | 1358 | 1358 |
| ENSMOCG00000010655 | 16.144671 | -0.3134907 | 0.2005447 | 0.0014700 | 0.0084827 | 101982260 | Kcnj14 | protein_coding | 101982260 | Kcnj14 | ENSMUSG00000058743 | Kcnj14 | ortholog_one2one | 97.4654 | ENSG00000182324 | KCNJ14 | ortholog_one2one | 93.7788 | NA | NA | NA | NA | NA | NA | 211480 | 211480 | 3770 | 3770 |
| ENSMOCG00000013070 | 36.387235 | -0.4123007 | 0.4014397 | 0.0015074 | 0.0086761 | NA | protein_coding | NA | ENSMUSG00000068587 | Mgam | ortholog_one2one | 83.0416 | ENSG00000257335 | MGAM | ortholog_one2one | 78.9982 | NA | NA | NA | NA | NA | NA | 232714 | 232714 | 8972 | 8972 | ||
| ENSMOCG00000012416 | 27.701155 | 0.2705027 | 0.1546208 | 0.0015396 | 0.0088233 | 101984299 | Bmp6 | protein_coding | 101984299 | Bmp6 | ENSMUSG00000039004 | Bmp6 | ortholog_one2one | 95.0298 | ENSG00000153162 | BMP6 | ortholog_one2one | 91.2525 | NA | NA | NA | NA | NA | NA | 12161 | 12161 | 654 | 654 |
| ENSMOCG00000017374 | 37.855099 | 0.2869905 | 0.1731140 | 0.0015494 | 0.0088700 | 101992489 | Ifitm3 | protein_coding | 101992489 | Ifitm3 | ENSMUSG00000025492 | Ifitm3 | ortholog_one2one | 82.4818 | ENSG00000185201 | IFITM2 | ortholog_many2many | 61.3139 | ENSMUSG00000025492, ENSMUSG00000025492, ENSMUSG00000025492 | Ifitm3, Ifitm3, Ifitm3 | 82.4818, 82.4818, 82.4818 | ENSG00000185201, ENSG00000142089, ENSG00000185885 | IFITM2, IFITM3, IFITM1 | 61.3139, 59.854, 52.5547 | 66141 | 66141 | 10581 | 10581 |
| ENSMOCG00000015114 | 48.390042 | 0.3253383 | 0.2186385 | 0.0015531 | 0.0088700 | 101991383 | Trem2 | protein_coding | 101991383 | Trem2 | ENSMUSG00000023992 | Trem2 | ortholog_one2one | 79.6681 | ENSG00000095970 | TREM2 | ortholog_one2one | 55.6017 | NA | NA | NA | NA | NA | NA | 83433 | 83433 | 54209 | 54209 |
| ENSMOCG00000016080 | 14.885004 | 0.3416658 | 0.2397385 | 0.0015563 | 0.0088846 | 101979233 | Rarres1 | protein_coding | 101979233 | Rarres1 | ENSMUSG00000049404 | Rarres1 | ortholog_one2one | 76.7606 | ENSG00000118849 | RARRES1 | ortholog_one2one | 70.0704 | NA | NA | NA | NA | NA | NA | 109222 | 109222 | 5918 | 5918 |
| ENSMOCG00000017640 | 17.162113 | -0.3459131 | 0.2522926 | 0.0016698 | 0.0094393 | 101981922 | Zbtb7c | protein_coding | 101981922 | Zbtb7c | ENSMUSG00000044646 | Zbtb7c | ortholog_one2one | 95.6381 | ENSG00000184828 | ZBTB7C | ortholog_one2one | 94.3457 | NA | NA | NA | NA | NA | NA | 207259 | 207259 | 201501 | 201501 |
| ENSMOCG00000015670 | 9.803717 | -0.3894954 | 0.3474923 | 0.0017378 | 0.0097124 | 101979496 | Tcte1 | protein_coding | 101979496 | Tcte1 | ENSMUSG00000023949 | Tcte1 | ortholog_one2one | 82.7655 | ENSG00000146221 | TCTE1 | ortholog_one2one | 76.1523 | NA | NA | NA | NA | NA | NA | 21645 | 21645 | 202500 | 202500 |
| ENSMOCG00000016766 | 20.145673 | -0.2915074 | 0.1852961 | 0.0017519 | 0.0097777 | 101998485 | Gprin2 | protein_coding | 101998485 | Gprin2 | ENSMUSG00000071531 | Gprin2 | ortholog_one2one | 84.8552 | ENSG00000204175 | GPRIN2 | ortholog_one2one | 74.1648 | NA | NA | NA | NA | NA | NA | 432839 | 432839 | 9721 | 9721 |
| ENSMOCG00000015887 | 30.370648 | -0.2598904 | 0.1494957 | 0.0017811 | 0.0099046 | 101980636 | Dsg2 | protein_coding | 101980636 | Dsg2 | ENSMUSG00000044393 | Dsg2 | ortholog_one2one | 83.6299 | ENSG00000046604 | DSG2 | ortholog_one2one | 74.4662 | NA | NA | NA | NA | NA | NA | 13511 | 13511 | 1829 | 1829 |
| ENSMOCG00000016665 | 21.611172 | -0.3089784 | 0.2089192 | 0.0018009 | 0.0099856 | NA | Mms22l | protein_coding | NA | Mms22l | ENSMUSG00000045751 | Mms22l | ortholog_one2one | 86.8662 | ENSG00000146263 | MMS22L | ortholog_one2one | 79.4680 | NA | NA | NA | NA | NA | NA | 212377 | 212377 | 253714 | 253714 |
| ENSMOCG00000010637 | 25.821822 | 0.3444873 | 0.2595343 | 0.0018214 | 0.0100670 | NA | processed_pseudogene | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000017518 | 22.830217 | -0.2847092 | 0.1820352 | 0.0019044 | 0.0104164 | 101985521 | Septin1 | protein_coding | 101985521 | Septin1 | ENSMUSG00000000486 | Septin1 | ortholog_one2one | 97.5477 | ENSG00000180096 | SEPTIN1 | ortholog_one2one | 95.0954 | NA | NA | NA | NA | NA | NA | 54204, 100043580 | 54204 | 1731 | 1731 |
| ENSMOCG00000004015 | 35.067171 | 0.2676377 | 0.1625271 | 0.0019442 | 0.0105994 | 101998544 | Tlr2 | protein_coding | 101998544 | Tlr2 | ENSMUSG00000027995 | Tlr2 | ortholog_one2one | 82.5032 | ENSG00000137462 | TLR2 | ortholog_one2one | 71.5198 | NA | NA | NA | NA | NA | NA | 24088 | 24088 | 7097 | 7097 |
| ENSMOCG00000017494 | 23.761136 | -0.2794670 | 0.1778074 | 0.0019777 | 0.0107423 | 101985461 | protein_coding | 101985461 | ENSMUSG00000028974 | Dffa | ortholog_one2many | 81.9876 | ENSG00000160049 | DFFA | ortholog_one2many | 73.6025 | NA | NA | NA | NA | NA | NA | 13347 | 13347 | 1676 | 1676 | ||
| ENSMOCG00000012380 | 13.341668 | -0.3670625 | 0.3182856 | 0.0019915 | 0.0107896 | 101993983 | protein_coding | 101993983 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000018957 | 14.218769 | -0.3186895 | 0.2303251 | 0.0019921 | 0.0107896 | NA | Pcdha1 | protein_coding | NA | Pcdha1 | ENSMUSG00000103442 | Pcdha1 | ortholog_one2one | 86.0656 | ENSG00000204970 | PCDHA1 | ortholog_one2one | 78.9227 | NA | NA | NA | NA | NA | NA | 116731 | 116731 | 56147 | 56147 |
| ENSMOCG00000013197 | 26.799082 | -0.2665972 | 0.1642972 | 0.0020594 | 0.0110644 | 101990097 | Cfap300 | protein_coding | 101990097 | Cfap300 | ENSMUSG00000053070 | Cfap300 | ortholog_one2one | 92.8839 | ENSG00000137691 | CFAP300 | ortholog_one2one | 83.1461 | NA | NA | NA | NA | NA | NA | 234912 | 234912 | 85016 | 85016 |
| ENSMOCG00000018460 | 19.502796 | -0.3078168 | 0.2181718 | 0.0020672 | 0.0110971 | 101988887 | Mmp28 | protein_coding | 101988887 | Mmp28 | ENSMUSG00000020682 | Mmp28 | ortholog_one2one | 91.1538 | ENSG00000271447 | MMP28 | ortholog_one2one | 84.0385 | NA | NA | NA | NA | NA | NA | 118453 | 118453 | 79148 | 79148 |
| ENSMOCG00000017485 | 24.759393 | -0.2826674 | 0.1866524 | 0.0021351 | 0.0114068 | 101999907 | Lrrc3 | protein_coding | 101999907 | Lrrc3 | ENSMUSG00000051652 | Lrrc3 | ortholog_one2one | 98.4064 | ENSG00000160233 | LRRC3 | ortholog_one2one | 80.0797 | NA | NA | NA | NA | NA | NA | 237387 | 237387 | 81543 | 81543 |
| ENSMOCG00000017101 | 36.727155 | 0.3048191 | 0.2178478 | 0.0021652 | 0.0115419 | NA | protein_coding | NA | ENSMUSG00000007646 | Rad51c | ortholog_one2many | 78.1250 | ENSG00000108384 | RAD51C | ortholog_one2many | 79.5455 | NA | NA | NA | NA | NA | NA | 114714 | 114714 | 5889 | 5889 | ||
| ENSMOCG00000021075 | 451.535464 | 0.3176995 | 0.2387776 | 0.0022072 | 0.0117212 | 101987932 | Riox2 | protein_coding | 101987932 | Riox2 | ENSMUSG00000022724 | Riox2 | ortholog_one2one | 75.3219 | ENSG00000170854 | RIOX2 | ortholog_one2one | 75.1073 | NA | NA | NA | NA | NA | NA | 67014 | 67014 | 84864 | 84864 |
| ENSMOCG00000009377 | 22.705799 | -0.2785841 | 0.1835658 | 0.0022101 | 0.0117273 | 101995895 | F7 | protein_coding | 101995895 | F7 | ENSMUSG00000031443 | F7 | ortholog_one2one | 81.8792 | ENSG00000057593 | F7 | ortholog_one2one | 70.6935 | NA | NA | NA | NA | NA | NA | 14068 | 14068 | 2155 | 2155 |
| ENSMOCG00000014197 | 5790.279175 | -0.2874519 | 0.1954585 | 0.0022130 | 0.0117383 | 102001059 | Sparc | protein_coding | 102001059 | Sparc | ENSMUSG00000018593 | Sparc | ortholog_one2one | 96.3087 | ENSG00000113140 | SPARC | ortholog_one2one | 93.6242 | NA | NA | NA | NA | NA | NA | 20692 | 20692 | 6678 | 6678 |
| ENSMOCG00000013340 | 17.414164 | -0.2929110 | 0.2050845 | 0.0022762 | 0.0120161 | 101986608 | Asb2 | protein_coding | 101986608 | Asb2 | ENSMUSG00000021200 | Asb2 | ortholog_one2one | 93.6609 | ENSG00000100628 | ASB2 | ortholog_one2one | 88.2726 | NA | NA | NA | NA | NA | NA | 65256 | 65256 | 51676 | 51676 |
| ENSMOCG00000020331 | 83.065910 | 0.3600868 | 0.3560152 | 0.0023075 | 0.0121379 | NA | Mylk | protein_coding | NA | Mylk | ENSMUSG00000022836 | Mylk | ortholog_one2one | 89.8669 | ENSG00000065534 | MYLK | ortholog_one2one | 84.0328 | NA | NA | NA | NA | NA | NA | 107589 | 107589 | 4638 | 4638 |
| ENSMOCG00000020980 | 30.017660 | 0.3075745 | 0.2278804 | 0.0023136 | 0.0121505 | 101984266 | Colq | protein_coding | 101984266 | Colq | ENSMUSG00000057606 | Colq | ortholog_one2one | 94.0266 | ENSG00000206561 | COLQ | ortholog_one2one | 89.3805 | NA | NA | NA | NA | NA | NA | 382864, 102639719 | 382864 | 8292 | 8292 |
| ENSMOCG00000011435 | 17.476812 | -0.3391287 | 0.2851305 | 0.0023439 | 0.0122758 | NA | Snora61 | snoRNA | NA | Snora61 | ENSMUSG00000064949 | Snora61 | ortholog_one2one | 89.1473 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | |||
| ENSMOCG00000000960 | 21.751030 | -0.2579097 | 0.1618519 | 0.0024013 | 0.0125174 | 101994078 | Slc7a7 | protein_coding | 101994078 | Slc7a7 | ENSMUSG00000000958 | Slc7a7 | ortholog_one2one | 92.7451 | ENSG00000155465 | SLC7A7 | ortholog_one2one | 90.3922 | NA | NA | NA | NA | NA | NA | 20540 | 20540 | 9056 | 9056 |
| ENSMOCG00000017712 | 138.830508 | 0.2948527 | 0.2131793 | 0.0024280 | 0.0126191 | NA | protein_coding | NA | NA | ENSG00000114784 | EIF1B | ortholog_one2one | 98.2456 | NA | NA | NA | NA | NA | NA | NA | NA | 10289 | 10289 | |||||
| ENSMOCG00000017323 | 18.813651 | -0.2668260 | 0.1746519 | 0.0024519 | 0.0127065 | NA | protein_coding | NA | ENSMUSG00000006728 | Cdk4 | ortholog_one2many | 95.8188 | ENSG00000135446 | CDK4 | ortholog_one2many | 93.7282 | NA | NA | NA | NA | NA | NA | 12567 | 12567 | 1019 | 1019 | ||
| ENSMOCG00000007045 | 41.065814 | -0.2595973 | 0.1653325 | 0.0024584 | 0.0127305 | NA | Ccdc81 | protein_coding | NA | Ccdc81 | ENSMUSG00000039391 | Ccdc81 | ortholog_one2one | 88.7205 | ENSG00000149201 | CCDC81 | ortholog_one2one | 80.3030 | NA | NA | NA | NA | NA | NA | 70884 | 70884 | 60494 | 60494 |
| ENSMOCG00000020367 | 25.134214 | 0.2733077 | 0.1850941 | 0.0025145 | 0.0129909 | 101992362 | Chrna1 | protein_coding | 101992362 | Chrna1 | ENSMUSG00000027107 | Chrna1 | ortholog_one2one | 97.1554 | ENSG00000138435 | CHRNA1 | ortholog_one2one | 92.7790 | NA | NA | NA | NA | NA | NA | 11435 | 11435 | 1134 | 1134 |
| ENSMOCG00000018829 | 63.912326 | -0.2628969 | 0.1726181 | 0.0025817 | 0.0132662 | 101998963 | Itgb4 | protein_coding | 101998963 | Itgb4 | ENSMUSG00000020758 | Itgb4 | ortholog_one2one | 95.4796 | ENSG00000132470 | ITGB4 | ortholog_one2one | 88.9195 | NA | NA | NA | NA | NA | NA | 192897 | 192897 | 3691 | 3691 |
| ENSMOCG00000019880 | 32.136160 | -0.2762161 | 0.1915860 | 0.0026006 | 0.0133426 | NA | Col23a1 | protein_coding | NA | Col23a1 | ENSMUSG00000063564 | Col23a1 | ortholog_one2one | 94.1729 | ENSG00000050767 | COL23A1 | ortholog_one2one | 88.9098 | NA | NA | NA | NA | NA | NA | 237759 | 237759 | 91522 | 91522 |
| ENSMOCG00000003565 | 28.183473 | -0.2906861 | 0.2143515 | 0.0026426 | 0.0135062 | 101999223 | Glra3 | protein_coding | 101999223 | Glra3 | ENSMUSG00000038257 | Glra3 | ortholog_one2one | 98.9224 | ENSG00000145451 | GLRA3 | ortholog_one2one | 98.0603 | NA | NA | NA | NA | NA | NA | 110304 | 110304 | 8001 | 8001 |
| ENSMOCG00000018064 | 20.976817 | -0.2851460 | 0.2060718 | 0.0026475 | 0.0135172 | 102000477 | Cklf | protein_coding | 102000477 | Cklf | ENSMUSG00000054400 | Cklf | ortholog_one2one | 63.3987 | ENSG00000217555 | CKLF | ortholog_one2one | 67.3203 | NA | NA | NA | NA | NA | NA | 75458 | 75458 | 51192 | 51192 |
| ENSMOCG00000019180 | 11.329218 | -0.3200277 | 0.4307053 | 0.0026478 | 0.0135172 | NA | protein_coding | NA | ENSMUSG00000030795 | Fus | ortholog_one2many | 90.2808 | ENSG00000089280 | FUS | ortholog_one2many | 88.3369 | NA | NA | NA | NA | NA | NA | 233908 | 233908 | 2521 | 2521 | ||
| ENSMOCG00000004441 | 93.871896 | -0.2535020 | 0.1626388 | 0.0026942 | 0.0137329 | NA | protein_coding | NA | NA | ENSG00000182793 | GSTA5 | ortholog_one2one | 53.0612 | NA | NA | NA | NA | NA | NA | NA | NA | 221357 | 221357 | |||||
| ENSMOCG00000015095 | 26.211899 | -0.2846654 | 0.2070684 | 0.0027017 | 0.0137605 | 101985986 | Rdm1 | protein_coding | 101985986 | Rdm1 | ENSMUSG00000010362 | Rdm1 | ortholog_one2one | 80.1471 | ENSG00000278023 | RDM1 | ortholog_one2one | 68.3824 | NA | NA | NA | NA | NA | NA | 66599 | 66599 | 201299 | 201299 |
| ENSMOCG00000018779 | 21.388056 | -0.2664499 | 0.1809294 | 0.0027200 | 0.0138482 | 105358997 | Synb | protein_coding | 105358997 | Synb | ENSMUSG00000047977 | Synb | ortholog_one2many | 86.5478 | ENSG00000244476 | ERVFRD-1 | ortholog_one2one | 25.1216 | ENSMUSG00000047977, ENSMUSG00000098773 | Synb, Gm27179 | 86.5478, 86.5478 | ENSG00000244476, ENSG00000244476 | ERVFRD-1, ERVFRD-1 | 25.1216, 25.1216 | 239167, 118567354 | 239167 | 405754 | 405754 |
| ENSMOCG00000018661 | 21.950332 | 0.2962810 | 0.2271925 | 0.0027519 | 0.0139787 | 101998982 | Ranbp3l | protein_coding | 101998982 | Ranbp3l | ENSMUSG00000048424 | Ranbp3l | ortholog_one2one | 72.9339 | ENSG00000164188 | RANBP3L | ortholog_one2one | 63.0165 | NA | NA | NA | NA | NA | NA | 223332 | 223332 | 202151 | 202151 |
| ENSMOCG00000016418 | 13.505400 | -0.3185098 | 0.2699373 | 0.0027838 | 0.0141084 | 101991995 | Pkp1 | protein_coding | 101991995 | Pkp1 | ENSMUSG00000026413 | Pkp1 | ortholog_one2one | 96.4237 | ENSG00000081277 | PKP1 | ortholog_one2one | 95.0481 | NA | NA | NA | NA | NA | NA | 18772 | 18772 | 5317 | 5317 |
| ENSMOCG00000017344 | 16.449621 | -0.2681610 | 0.1862501 | 0.0028323 | 0.0142919 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000006777 | 23.670218 | -0.3175062 | 0.2724897 | 0.0028631 | 0.0144280 | 101985059 | Cfap161 | protein_coding | 101985059 | Cfap161 | ENSMUSG00000011154 | Cfap161 | ortholog_one2one | 77.9605 | ENSG00000156206 | CFAP161 | ortholog_one2one | 71.7105 | NA | NA | NA | NA | NA | NA | 75556 | 75556 | 161502 | 161502 |
| ENSMOCG00000022188 | 71.468458 | -0.2592159 | 0.1753397 | 0.0029127 | 0.0146068 | 101999781 | Adra2a | protein_coding | 101999781 | Adra2a | ENSMUSG00000033717 | Adra2a | ortholog_one2one | 97.8402 | ENSG00000150594 | ADRA2A | ortholog_one2one | 92.6566 | NA | NA | NA | NA | NA | NA | 11551 | 11551 | 150 | 150 |
| ENSMOCG00000018162 | 24.547569 | -0.3013198 | 0.2430837 | 0.0029298 | 0.0146702 | 101985464 | Ppp1r36 | protein_coding | 101985464 | Ppp1r36 | ENSMUSG00000052221 | Ppp1r36 | ortholog_one2one | 83.4951 | ENSG00000165807 | PPP1R36 | ortholog_one2one | 75.4854 | NA | NA | NA | NA | NA | NA | 210762 | 210762 | 145376 | 145376 |
| ENSMOCG00000010076 | 17.096797 | -0.2897186 | 0.2234185 | 0.0029502 | 0.0147335 | 101992523 | Chrm5 | protein_coding | 101992523 | Chrm5 | ENSMUSG00000074939 | Chrm5 | ortholog_one2one | 92.4528 | ENSG00000184984 | CHRM5 | ortholog_one2one | 88.1132 | NA | NA | NA | NA | NA | NA | 213788 | 213788 | 1133 | 1133 |
| ENSMOCG00000021966 | 38.626363 | 0.2585014 | 0.1755525 | 0.0029665 | 0.0147868 | 101982882 | Adamtsl3 | protein_coding | 101982882 | Adamtsl3 | ENSMUSG00000070469 | Adamtsl3 | ortholog_one2one | 89.1304 | ENSG00000156218 | ADAMTSL3 | ortholog_one2one | 84.1951 | NA | NA | NA | NA | NA | NA | 269959 | 269959 | 57188 | 57188 |
| ENSMOCG00000014229 | 16.229655 | -0.2914303 | 0.2302884 | 0.0030592 | 0.0151924 | 101979273 | Evpl | protein_coding | 101979273 | Evpl | ENSMUSG00000034282 | Evpl | ortholog_one2one | 89.1026 | ENSG00000167880 | EVPL | ortholog_one2one | 82.8402 | NA | NA | NA | NA | NA | NA | 14027 | 14027 | 2125 | 2125 |
| ENSMOCG00000005890 | 19.651516 | -0.3125020 | 0.2747670 | 0.0030916 | 0.0153246 | 101985751 | Tafa1 | protein_coding | 101985751 | Tafa1 | ENSMUSG00000059187 | Tafa1 | ortholog_one2one | 99.2481 | ENSG00000183662 | TAFA1 | ortholog_one2one | 100.0000 | NA | NA | NA | NA | NA | NA | 320265 | 320265 | 407738 | 407738 |
| ENSMOCG00000017548 | 80.783532 | 0.3209455 | 0.3089077 | 0.0031792 | 0.0156831 | NA | protein_coding | NA | NA | ENSG00000108518 | PFN1 | ortholog_one2many | 95.3271 | NA | NA | NA | NA | NA | NA | NA | NA | 5216 | 5216 | |||||
| ENSMOCG00000010647 | 13.402039 | -0.3191754 | 0.3057837 | 0.0032168 | 0.0158565 | 101982699 | Art3 | protein_coding | 101982699 | Art3 | ENSMUSG00000034842 | Art3 | ortholog_one2one | 56.8475 | ENSG00000156219 | ART3 | ortholog_one2one | 56.5891 | NA | NA | NA | NA | NA | NA | 109979 | 109979 | 419 | 419 |
| ENSMOCG00000000797 | 15.609609 | -0.3090052 | 0.2748998 | 0.0032352 | 0.0159179 | 101996245 | Ankrd66 | protein_coding | 101996245 | Ankrd66 | ENSMUSG00000096140 | Ankrd66 | ortholog_one2one | 86.4583 | ENSG00000230062 | ANKRD66 | ortholog_one2one | 81.2500 | NA | NA | NA | NA | NA | NA | 100043332 | 100043332 | 100287718 | 100287718 |
| ENSMOCG00000010633 | 23.208178 | -0.2719461 | 0.2032246 | 0.0032490 | 0.0159740 | NA | Gsap | protein_coding | NA | Gsap | ENSMUSG00000039934 | Gsap | ortholog_one2one | 80.8618 | ENSG00000186088 | GSAP | ortholog_one2one | 73.0038 | NA | NA | NA | NA | NA | NA | 212167 | 212167 | 54103 | 54103 |
| ENSMOCG00000021689 | 13.179114 | -0.3163295 | 0.3756819 | 0.0032544 | 0.0159946 | NA | Ighm | protein_coding | NA | Ighm | ENSMUSG00000076617 | Ighm | ortholog_one2one | 79.2952 | ENSG00000211899 | IGHM | ortholog_one2one | 63.8767 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| ENSMOCG00000012111 | 45.190435 | -0.3119984 | 0.2930186 | 0.0033619 | 0.0164502 | 101992531 | Dnah10 | protein_coding | 101992531 | Dnah10 | ENSMUSG00000038011 | Dnah10 | ortholog_one2one | 93.2680 | ENSG00000197653 | DNAH10 | ortholog_one2one | 89.1721 | NA | NA | NA | NA | NA | NA | 56087 | 56087 | 196385 | 196385 |
| ENSMOCG00000017284 | 28.052216 | -0.2735587 | 0.2101111 | 0.0033966 | 0.0165594 | 101980497 | protein_coding | 101980497 | NA | ENSG00000137875 | BCL2L10 | ortholog_one2one | 51.5957 | NA | NA | NA | NA | NA | NA | NA | NA | 10017 | 10017 | |||||
| ENSMOCG00000019942 | 15.805816 | 0.2646141 | 0.1969556 | 0.0034665 | 0.0168321 | 101982659 | Sgca | protein_coding | 101982659 | Sgca | ENSMUSG00000001508 | Sgca | ortholog_one2one | 93.2817 | ENSG00000108823 | SGCA | ortholog_one2one | 88.6305 | NA | NA | NA | NA | NA | NA | 20391 | 20391 | 6442 | 6442 |
| ENSMOCG00000014407 | 19.162787 | -0.2930537 | 0.2539962 | 0.0035671 | 0.0172140 | 101985203 | Spaca9 | protein_coding | 101985203 | Spaca9 | ENSMUSG00000026809 | Spaca9 | ortholog_one2one | 95.2381 | ENSG00000165698 | SPACA9 | ortholog_one2one | 93.4524 | NA | NA | NA | NA | NA | NA | 69987 | 69987 | 11092 | 11092 |
| ENSMOCG00000017568 | 18.542508 | -0.2906016 | 0.2508293 | 0.0036208 | 0.0174288 | 101987825 | Ankrd34c | protein_coding | 101987825 | Ankrd34c | ENSMUSG00000047606 | Ankrd34c | ortholog_one2one | 92.3221 | ENSG00000235711 | ANKRD34C | ortholog_one2one | 90.2622 | NA | NA | NA | NA | NA | NA | 330998 | 330998 | 390616 | 390616 |
| ENSMOCG00000001445 | 19.415452 | 0.2780979 | 0.2279820 | 0.0037070 | 0.0177539 | 101999680 | Aoah | protein_coding | 101999680 | Aoah | ENSMUSG00000021322 | Aoah | ortholog_one2one | 80.5217 | ENSG00000136250 | AOAH | ortholog_one2one | 73.7391 | NA | NA | NA | NA | NA | NA | 27052 | 27052 | 313 | 313 |
| ENSMOCG00000021008 | 20.925417 | -0.2971847 | 0.2744717 | 0.0037553 | 0.0179211 | 101988274 | Eya4 | protein_coding | 101988274 | Eya4 | ENSMUSG00000010461 | Eya4 | ortholog_one2one | 96.5909 | ENSG00000112319 | EYA4 | ortholog_one2one | 95.6169 | NA | NA | NA | NA | NA | NA | 14051 | 14051 | 2070 | 2070 |
| ENSMOCG00000003082 | 11.532388 | 0.3035886 | 0.3064114 | 0.0038234 | 0.0181873 | 101996643 | Ces2a | protein_coding | 101996643 | Ces2a | ENSMUSG00000055730 | Ces2a | ortholog_one2one | 77.3214 | ENSG00000172831 | CES2 | ortholog_one2many | 66.7857 | NA | NA | NA | NA | NA | NA | 102022 | 102022 | 8824 | 8824 |
| ENSMOCG00000004642 | 695.730018 | 0.2978861 | 0.3589151 | 0.0039142 | 0.0185203 | NA | protein_coding | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | ||||||||
| ENSMOCG00000022060 | 20.388672 | -0.2591755 | 0.2010226 | 0.0040054 | 0.0188981 | 101982092 | Col1a1 | protein_coding | 101982092 | Col1a1 | ENSMUSG00000001506 | Col1a1 | ortholog_one2one | 95.7330 | ENSG00000108821 | COL1A1 | ortholog_one2one | 92.7736 | NA | NA | NA | NA | NA | NA | 12842 | 12842 | 1277 | 1277 |
| ENSMOCG00000019421 | 86.206842 | -0.2532096 | 0.1911908 | 0.0040359 | 0.0190218 | 101982710 | Cfap65 | protein_coding | 101982710 | Cfap65 | ENSMUSG00000047021 | Cfap65 | ortholog_one2one | 83.1539 | ENSG00000181378 | CFAP65 | ortholog_one2one | 74.8116 | NA | NA | NA | NA | NA | NA | 241116 | 241116 | 255101 | 255101 |
| ENSMOCG00000014056 | 21.528848 | -0.2869139 | 0.2664770 | 0.0041447 | 0.0194042 | 101987994 | Daw1 | protein_coding | 101987994 | Daw1 | ENSMUSG00000053161 | Daw1 | ortholog_one2one | 95.1807 | ENSG00000123977 | DAW1 | ortholog_one2one | 87.9518 | NA | NA | NA | NA | NA | NA | 71227 | 71227 | 164781 | 164781 |
| ENSMOCG00000013038 | 19.523506 | -0.2845817 | 0.2768160 | 0.0044447 | 0.0205842 | 102001251 | Map3k19 | protein_coding | 102001251 | Map3k19 | ENSMUSG00000051590 | Map3k19 | ortholog_one2one | 76.6225 | ENSG00000176601 | MAP3K19 | ortholog_one2one | 52.7815 | NA | NA | NA | NA | NA | NA | 22625 | 22625 | 80122 | 80122 |
| ENSMOCG00000012735 | 72.576821 | -0.2755343 | 0.2706961 | 0.0048885 | 0.0221921 | 101997266 | Cyp2d22 | protein_coding | 101997266 | Cyp2d22 | ENSMUSG00000061740 | Cyp2d22 | ortholog_one2one | 83.4000 | ENSG00000100197 | CYP2D6 | ortholog_one2many | 74.4000 | NA | NA | NA | NA | NA | NA | 56448 | 56448 | 1565 | 1565 |
| ENSMOCG00000006939 | 24.625900 | -0.2599706 | 0.2289090 | 0.0049810 | 0.0225429 | 101997732 | Btn2a2 | protein_coding | 101997732 | Btn2a2 | ENSMUSG00000053216 | Btn2a2 | ortholog_one2one | 87.1595 | ENSG00000124508 | BTN2A2 | ortholog_one2one | 72.9572 | NA | NA | NA | NA | NA | NA | 238555 | 238555 | 10385 | 10385 |
| ENSMOCG00000009470 | 59.729272 | -0.2773709 | 0.2979292 | 0.0050519 | 0.0228405 | NA | protein_coding | NA | ENSMUSG00000090451 | Gm6133 | ortholog_one2many | 84.2391 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | |||||
| ENSMOCG00000022150 | 15.188854 | -0.2723219 | 0.2907810 | 0.0053123 | 0.0238158 | 101995809 | Col6a4 | protein_coding | 101995809 | Col6a4 | ENSMUSG00000032572 | Col6a4 | ortholog_one2one | 79.7089 | NA | NA | NA | NA | NA | NA | NA | 68553 | 68553 | NA | NA | |||
| ENSMOCG00000015191 | 13.408232 | -0.2692250 | 0.2780745 | 0.0053998 | 0.0241110 | 102002820 | Cfap126 | protein_coding | 102002820 | Cfap126 | ENSMUSG00000026649 | Cfap126 | ortholog_one2one | 79.4595 | ENSG00000188931 | CFAP126 | ortholog_one2one | 81.6216 | NA | NA | NA | NA | NA | NA | 75472 | 75472 | 257177 | 257177 |
| ENSMOCG00000022057 | 16.827280 | -0.2589592 | 0.2417526 | 0.0054518 | 0.0242535 | 101997206 | Cfap91 | protein_coding | 101997206 | Cfap91 | ENSMUSG00000022805 | Cfap91 | ortholog_one2one | 83.4850 | ENSG00000183833 | CFAP91 | ortholog_one2one | 75.6827 | NA | NA | NA | NA | NA | NA | 320214 | 320214 | 89876 | 89876 |
| ENSMOCG00000013404 | 37.506955 | -0.2657509 | 0.2911122 | 0.0057297 | 0.0251956 | 101999391 | Abcb11 | protein_coding | 101999391 | Abcb11 | ENSMUSG00000027048 | Abcb11 | ortholog_one2one | 85.1290 | ENSG00000073734 | ABCB11 | ortholog_one2one | 82.0941 | NA | NA | NA | NA | NA | NA | 27413 | 27413 | 8647 | 8647 |
| ENSMOCG00000010561 | 14.047355 | 0.2504039 | 0.2278781 | 0.0057610 | 0.0252999 | 101996859 | Cldn9 | protein_coding | 101996859 | Cldn9 | ENSMUSG00000066720 | Cldn9 | ortholog_one2one | 100.0000 | ENSG00000213937 | CLDN9 | ortholog_one2one | 97.2350 | NA | NA | NA | NA | NA | NA | 56863 | 56863 | 9080 | 9080 |
| ENSMOCG00000009321 | 67.870000 | -0.2522438 | 0.2557056 | 0.0063539 | 0.0273008 | 101999984 | Ndst4 | protein_coding | 101999984 | Ndst4 | ENSMUSG00000027971 | Ndst4 | ortholog_one2one | 97.0183 | ENSG00000138653 | NDST4 | ortholog_one2one | 95.5275 | NA | NA | NA | NA | NA | NA | 64580 | 64580 | 64579 | 64579 |
Volcano Plot
lab = unique(c(sig %>% head(n=15) %>% pull(external_gene_name),
sig %>% arrange(desc(abs(log2FoldChange))) %>% head(n=30) %>% pull(external_gene_name)))
g1 <- amanda.volcano.plot(mydf_all, " ", lab, FCcut = 0.25, Padjcut = 0.05) +
ylab("-log(adjusted pvalue)") + xlab("log2(Fold Change)") +
ggtitle("Volcano Plot of Genotype Differential Expression") +
theme(legend.justification=c(0,1), legend.position=c(0,1))
ggsave(plot=g1, file=paste0(output_dir, "figures/SuppFig6A_Volcano.svg"), width=10, height=7)Selected Gene Plot
id = sig %>% arrange(padj) %>% filter(external_gene_name %ni% c("", ",")) %>% head(n=6) %>% pull(ensembl_gene_id)
name = sig %>% arrange(padj) %>% filter(external_gene_name %ni% c("", ",")) %>% head(n=6) %>% pull(external_gene_name)
d <- ddsnorm %>%
data.frame() %>%
filter(row.names(ddsnorm) %in% id[1:6]) %>%
t() %>% data.frame() %>%
rownames_to_column() %>%
tidyr::pivot_longer(cols=-c(rowname), values_to='expr', names_to='gene') %>%
left_join(metadata[,c("SampleID", "species")], by=c("rowname"="SampleID")) %>%
left_join(vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("gene"="ensembl_gene_id"))
d$species <- as.factor(d$species)
d$species <- factor(d$species, levels=c("WT", "Mut6"))
d$external_gene_name <- as.factor(d$external_gene_name)
d$external_gene_name <- factor(d$external_gene_name, levels=name)
g1 <- ggplot(d, aes(x=species, y=log2(expr), fill=species)) +
geom_boxplot() +
geom_jitter(color="black", size=2, alpha=0.5, width = 0.1) +
facet_wrap(~external_gene_name, scales = "free_y") +
theme_bw() + xlab("") +
ylab("log2 Normalized Gene Expression") +
ggtitle("Top 6 DE Genes in Mutation (by Fold Change)") +
scale_x_discrete(labels = c("WT", expression(OXTR^"1-/-"))) +
scale_fill_manual(values=c("#774972","#D089DA")) +
theme(text=element_text(size=14, face = "bold"),
strip.text.x = element_text(size = 16),
plot.title = element_text(hjust = 0.5),
legend.position = "none", axis.text.x = element_text(angle = 45, hjust = 1))
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig6C_BoxPlot.svg"), width=10, height=7)
g1
MA Plot
l = data.frame(res_joint)
l$sig = ifelse(l$padj > 0.05 | is.na(l$padj) | abs(l$log2FoldChange) < 0.25, "NS", ifelse(l$log2FoldChange >0, "up", "down"))
l$sig <- as.factor(l$sig); l$sig <- factor(l$sig, levels=c("up", "down", "NS"))
l <- left_join(rownames_to_column(l),
vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("rowname" = "ensembl_gene_id"))
g1 <- ggplot(l, aes(x=log2(baseMean), y=log2FoldChange, col=sig)) +
geom_point(size=4) +
scale_color_manual(values=c("#B31B21", "#1465AC", "darkgray"), name="",
lab=c(paste0("Up: ",table(l$sig)[["up"]]),
paste0("Down: ",table(l$sig)[["down"]]),
"NS")) +
ylim(c(-8, 4)) +
theme_bw() +
xlab("Log2 Mean Expression") + ylab("Log2 Fold Change") +
ggtitle("WT vs OXTR1-/- MA plot") +
geom_hline(yintercept=c(0.25, -0.25), linetype = "dashed", linewidth=0.3) +
guides(color = guide_legend(direction = "horizontal")) +
#ggrepel::geom_text_repel(data=l[l$rowname %in% id[1:6], ], aes(label=external_gene_name),
# show.legend = F, size=4, box.padding = 0.5, segment.color = NA) +
theme(text=element_text(size=14, face = "bold"),
plot.title = element_text(hjust = 0.5),
legend.position=c(1, 1.03),
legend.justification="right")
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig6B_MAPlot.svg"), width=10, height=8)
g1
mymat <- ddsnorm %>%
data.frame() %>%
filter(row.names(ddsnorm) %in% x$Joint) %>%
rownames_to_column() %>%
left_join(vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("rowname"="ensembl_gene_id")) %>%
mutate(longer=ifelse(external_gene_name != "", external_gene_name, rowname)) %>%
column_to_rownames('longer') %>%
select(-c(external_gene_name, rowname))
scaled_mat = t(scale(t(mymat)))
ha = HeatmapAnnotation(
Pairing = tolower(gsub("_bond", "", colData(dds)$Condition)),
Genotype = ifelse(colData(dds)$species == "WT", "WT", "OXTR1-/-"),
Sex = colData(dds)$Sex,
col = list(
Genotype = c("WT" = "#774972", "OXTR1-/-"="#D089DA"),
Pairing = c("pre" = "#087B8B", "post" = "#E5A024"),
#Sex = c("F" = "#bf083d", "M"= "#2b4599")),
#Sex = c("F" = "#bf083d", "M"= "lightblue")),
Sex = c("F" = "black", "M"= "lightgrey")),
annotation_legend_param = list(
Pairing=list(at=c("pre","post"), nrow=1),
Genotype=list(at=c("WT","OXTR1-/-"), nrow=1),
Sex = list(at=c("F","M"), nrow=1)
)
)
ht <- Heatmap(scaled_mat, name = "Z-score", top_annotation = ha,
#col = colorRamp2(c(-2, 0, 2), hcl_palette = "Cork"),
show_column_names = FALSE, show_row_names=FALSE,
heatmap_legend_param = list(direction="horizontal", nrow=1),
row_title = "DE Genes", row_title_rot = 90,
column_title = "Samples", column_title_rot = 0, column_title_side = "bottom",
use_raster = TRUE)## 'magick' package is suggested to install to give better rasterization.
##
## Set `ht_opt$message = FALSE` to turn off this message.pdf(file=paste0(output_dir, "figures/Supp6B_Heatmap.pdf"), height = 10, width = 10)
draw(ht, merge_legend = TRUE)
dev.off()## quartz_off_screen
## 2draw(ht, merge_legend = TRUE)
mymat = ddsnorm[rownames(ddsnorm) %in% unique(c(x$Joint)), ]
rownames(mymat) <- paste0(rownames(mymat), ":",
vole_annotation[vole_annotation$ensembl_gene_id %in% rownames(mymat), "external_gene_name"])
scaled_mat = t(scale(t(mymat)))
ha = HeatmapAnnotation(
Genotype = colData(dds)$species,
Bonding = colData(dds)$Condition,
Sex = colData(dds)$Sex,
col = list(
Genotype = c("WT" = "#5c3c92", "Mut6"="#077b8a"),
Bonding = c("Pre_bond" = "#039fbe", "Post_bond" = "#e8d21d"),
Sex = c("F" = "#1e3d59", "M"= "#ff6e40")))
ht = Heatmap(scaled_mat, name = "Z-score",
top_annotation = ha, cluster_columns = TRUE,
show_column_names = FALSE, show_row_names=FALSE,
column_title = "OXTR -/- DEX Genes\n padj < 0.05 & abs(log2FC) > 0.25 (joint list)")
#doesn't print plot rn, leaving original version here. Pulling out some gene plots I think will be of interest.
ugh <- function(id, special=NULL){
suppressPackageStartupMessages({
library(glue)
library(ggtext)
})
fc <- format(mydf_all[mydf_all$ensembl_gene_id == id, "log2FoldChange"], digits=3)
padj <- format(mydf_all[mydf_all$ensembl_gene_id == id, "padj"], digits=3)
name <- ifelse(is.null(special),
mydf_all[mydf_all$ensembl_gene_id == id, "external_gene_name"],
special)
#return(paste0(name,"\npadj:", padj, " log2FC=", fc))
#return(list(name, paste0("padj:", padj, "\nlog2FC", fc)))
return(glue("{name}<br><span style='font-size:9pt'>padj: {padj} log2FC: {fc}</span>"))
}
id = c("ENSMOCG00000020811", "ENSMOCG00000004545", "ENSMOCG00000002867", "V1A")
name = c("Calcr", "Dlk1", "OXTR", "V1A")
d <- ddsnorm_all %>%
data.frame() %>%
filter(row.names(ddsnorm_all) %in% id) %>%
t() %>% data.frame() %>%
rownames_to_column() %>%
tidyr::pivot_longer(cols=-c(rowname), values_to='expr', names_to='gene') %>%
left_join(metadata[,c("SampleID", "species")], by=c("rowname"="SampleID")) %>%
left_join(vole_annotation[,c("ensembl_gene_id", "external_gene_name")], by=c("gene"="ensembl_gene_id"))
d[d$gene == "V1A", "external_gene_name"] = "V1A"
d$species <- as.factor(d$species)
d$species <- factor(d$species, levels=c("WT", "Mut6"))
d$external_gene_name <- as.factor(d$external_gene_name)
d$external_gene_name <- factor(d$external_gene_name, levels=c(name[1], name[2], name[3], name[4]),
labels=c(ugh(id[1]), ugh(id[2]), ugh(id[3]), ugh(id[4], special="V1A")))g1 <- ggplot(d[d$gene %in% id[1:2], ], aes(x=species, y=log2(expr), fill=species)) +
geom_boxplot() +
geom_jitter(color="black", size=2, alpha=0.5, width = 0.1) +
facet_wrap(~external_gene_name, scales = "free_y") +
theme_bw() + xlab("") +
ylab("log2 Normalized Gene Expression") +
scale_x_discrete(labels = c("WT", expression(OXTR^"1-/-"))) +
scale_fill_manual(values=c("#774972","#D089DA")) +
theme(text=element_text(size=14, face = "bold"),
strip.text=element_markdown(size = 14, lineheight = 1.1),
plot.title = element_text(hjust = 0.5),
plot.subtitle = element_text(hjust = 0.5, size=12),
legend.position = "none", axis.text.x = element_text(angle = 45, hjust = 1))
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig6G_BoxPlot.svg"), width=10, height=7)
g1
g2 <- ggplot(d[d$gene %in% id[3:4], ], aes(x=species, y=log2(expr), fill=species)) +
geom_boxplot() +
geom_jitter(color="black", size=2, alpha=0.5, width = 0.1) +
facet_wrap(~external_gene_name, scales = "free_y") +
theme_bw() + xlab("") +
ylab("log2 Normalized Gene Expression") +
scale_x_discrete(labels = c("WT", expression(OXTR^"1-/-"))) +
scale_fill_manual(values=c("#774972","#D089DA")) +
theme(text=element_text(size=14, face = "bold"),
strip.text=element_markdown(size = 14, lineheight = 1.1),
plot.title = element_text(hjust = 0.5),
plot.subtitle = element_text(hjust = 0.5, size=12),
legend.position = "none", axis.text.x = element_text(angle = 45, hjust = 1))
ggsave(plot=g2, file=paste0(output_dir, "figures/SuppFig6D_BoxPlot.svg"), width=10, height=7)
g2
metadata$tmp <- paste0(metadata$species, "_",metadata$Sex)
amanda.quick.boxplots(ddsnorm_all, "V1A", "V1A\npadj:0.0298 log2FC=-0.246", "tmp",
c("WT_F","WT_M", "Mut6_F", "Mut6_M")) +
scale_fill_manual(values=c("#56B4E9","#56B4E9", "#E69F00", "#E69F00"))
write.csv(sig, file=paste0(output_dir, "Genotype_DEX.csv"))#Note, these are genes that are dex with abs(log2FC) > 1 in either female but not male, or male but not female
write.csv(maybesexspecific, file=paste0(output_dir, "Genotype_DEX_SexSpecific.csv"))save.image(file="~/Desktop/vole_checkpoint.RData")Enrichment: Gene Ontology
suppressPackageStartupMessages({
library(org.Mm.eg.db)
library(goseq)
library(GO.db)
library(clusterProfiler)
library(org.Mm.eg.db)
library(enrichplot)
library(GOSemSim)
library(scales)
})
# goseq:::.ORG_PACKAGES #doesn't offer voles unsurprisingly. lets try go for mm
getGeneLists <- function(pwf, goterms, genome="mm9", ids="ensGene"){
#credit: https://www.biostars.org/p/355247/
gene2cat <- getgo(rownames(pwf), genome, ids)
cat2gene <- split(rep(names(gene2cat), sapply(gene2cat, length)),
unlist(gene2cat, use.names = FALSE))
out <- list()
for(term in goterms){
tmp <- pwf[cat2gene[[term]],]
tmp <- rownames(tmp[tmp$DEgenes > 0, ])
out[[term]] <- tmp
}
out
}
quickie <- function(l, var="ensembl_gene_id"){
#small function to pull gene IDs for each category
m <- paste0(vole_annotation[vole_annotation$mmusculus_homolog_ensembl_gene %in% l, var], collapse=",")
return(m)
}
add_totals <- function(cont2x2){
m <- rbind(cont2x2, "total"=0); m$total <- 0;
m["total","total"] = sum(m)
m["total",1] <- sum(m[,1]); m["total",2] <- sum(m[,2])
m[1,"total"] <- sum(m[1,]); m[2,"total"] <- sum(m[2,])
return(m)
}
new_volcano <- function(results, title, gene.list=NA){
results <- data.frame(results)
results <- results[!is.na(results$padj) & !is.na(results$log2FoldChange) ,]
results$sig <- ifelse(results$padj < 0.05, "sig", "notsig")
results[results$mmusculus_homolog_ensembl_gene %in% gene.list, "sig"] <- "driving_GO"
results$sig <- as.factor(results$sig); results$sig <- factor(results$sig, levels = c("notsig", "sig", "driving_GO"))
to_label <- results[results$sig == "driving_GO", ]
ugh <- nrow(to_label)
p1 <- ggplot(results, aes(x=log2FoldChange, y=-log10(padj))) +
geom_point(aes(color = sig)) +
ggtitle(title) +
xlab("log2FC") + ylab("-log10(padj)") +
scale_colour_manual(values = c("black", "darkgrey", "blue"), name ="",
labels=c("not signficant", "significant (p < 0.05)", paste0("driving_GO (N=",ugh,")"))) +
theme_bw() +
theme(legend.justification=c(1,0), legend.position=c(1,0), legend.title = element_blank(),
legend.background = element_rect(fill="transparent", linewidth=0.5, linetype="solid", color = "black")) +
ggrepel::geom_text_repel(data=results[results$sig == "driving_GO", ],
aes(label=paste0(external_gene_name, ":", mmusculus_homolog_ensembl_gene)), show.legend = F, size=2, col="blue") +
NULL
return(p1)
}
#convert a goseq object into a enrichRobject by hand.
amanda_enrichRobject <- function(degenes, backgroundgenes, enriched.GO){
results_df <- enriched.GO %>%
mutate(GeneRatio = paste0(numDEInCat, "/", length(degenes)),
BgRatio = paste0(numInCat, "/", length(backgroundgenes)),
qvalue=padj,
geneID = gsub(",", "/", mmusculus_homolog_ensembl_gene),
Count = numDEInCat) %>%
rename(ID=category, Description=term, pvalue=over_represented_pvalue, p.adjust=padj) %>%
dplyr::select(c(ID, Description, GeneRatio, BgRatio, pvalue, p.adjust, qvalue, geneID, Count))
geneSets <- lapply(enriched.GO$category, function(i)
unlist(strsplit(enriched.GO[enriched.GO$category == i, "mmusculus_homolog_ensembl_gene"], ",")))
names(geneSets) <- enriched.GO$category
ego <- new("enrichResult",
readable = FALSE,
result = results_df,
pvalueCutoff = 0.05,
pAdjustMethod = "BH",
organism = "UNKNOWN",
ontology = enriched.GO$ontology,
gene = degenes,
keytype = "ENSEMBL",
universe = backgroundgenes,
gene2Symbol = character(0),
geneSets = geneSets)
fc_list = lapply(ego@result$ID,
function(i) genotype_df %>%
filter(mmusculus_homolog_ensembl_gene %in% ego@geneSets[[i]]) %>%
pull(log2FC_F) %>%
median())
ego@result$median_log2fc = unlist(fc_list)
ego2 <- pairwise_termsim(ego, method="Wang", semData = godata('org.Mm.eg.db', ont="BP"))
return(ego2)
}DEgenes_mm <- vole_annotation %>%
filter(ensembl_gene_id %in% x$Joint) %>%
pull("mmusculus_homolog_ensembl_gene") %>% unique() %>% na.omit() %>% as.character()
backgroundGenes_mm = vole_annotation %>%
filter(ensembl_gene_id %in% rownames(cts)) %>%
pull("mmusculus_homolog_ensembl_gene") %>% unique() %>% na.omit() %>% as.character()
genes <- as.integer(backgroundGenes_mm %in% DEgenes_mm)
names(genes) <- (backgroundGenes_mm)
#run GO on joint list
pwf=nullp(genes, "mm9", "ensGene", plot.fit = FALSE) #obtain a weighting for each gene, depending on its length
GO.wall=goseq(pwf, "mm9", "ensGene")
ego <- GO.wall %>% mutate(padj = p.adjust(over_represented_pvalue, method="BH")) %>% filter(padj < 0.05)
goList <- getGeneLists(pwf, ego$category)
enriched.GO <- ego %>%
mutate(
mmusculus_homolog_ensembl_gene = sapply(category, function(x) paste0(goList[[x]], collapse = ",")),
ensembl_gene_id <- sapply(category, function(x) quickie(goList[[x]], var="ensembl_gene_id")),
external_gene_name <- sapply(category, function(x) quickie(goList[[x]], var="external_gene_name")))
cat("Number of enriched GO categories (joint):", nrow(enriched.GO))## Number of enriched GO categories (joint): 62ego2 <- amanda_enrichRobject(DEgenes_mm, backgroundGenes_mm, enriched.GO[enriched.GO$numInCat < 1000, ])
n = 5
mycol= hue_pal()(n)
p1 <- suppressWarnings(
treeplot(ego2, color="p.adjust", showCategory = 65,
cluster.params = list(color=mycol, n=n))
) +
scale_fill_manual(values=rep(c("white"), n)) +
scale_colour_continuous(low="cornflowerblue", high="red", name = "adjp",
guide = guide_colorbar(reverse = TRUE)) #+ theme(legend.position = "bottom")
p1$layers[[3]]$aes_params$size <- 3 # clusters
p1$layers[[7]]$aes_params$size <- 3 #tree labels
#p2 <- treeplot(ego2, color="median_log2fc", showCategory = 65,
# cluster.params = list(color=mycol, n=n)) +
# scale_fill_manual(values=rep(c("white"), n)) +
# scale_colour_continuous(low="cornflowerblue", high="red", name = #"median_log2fc",
# guide = guide_colorbar(reverse = TRUE)) #+ theme(legend.position = #"bottom")
#p2$layers[[3]]$aes_params$size <- 3 # clusters
#p2$layers[[7]]$aes_params$size <- 3 #tree labelsp1 + ggtitle("All terms: nodes colored by padj")
GO by fold change
#run GO on up/down regulation
DEgenes_ups <- mydf_all %>%
filter(padj < 0.05 & log2FoldChange > 0.25) %>%
pull("mmusculus_homolog_ensembl_gene") %>% unique() %>% na.omit() %>% as.character()
genes <- as.integer(backgroundGenes_mm %in% DEgenes_ups)
names(genes) <- (backgroundGenes_mm)
pwf=nullp(genes, "mm9", "ensGene", plot.fit = FALSE) #obtain a weighting for each gene, depending on its length
GO.wall=goseq(pwf, "mm9", "ensGene")
ego <- GO.wall %>% mutate(padj = p.adjust(over_represented_pvalue, method="BH")) %>% filter(padj < 0.05)
goList <- getGeneLists(pwf, ego$category)
enriched.GO_up <- ego %>%
mutate(
mmusculus_homolog_ensembl_gene = sapply(category, function(x) paste0(goList[[x]], collapse = ",")),
ensembl_gene_id <- sapply(category, function(x) quickie(goList[[x]], var="ensembl_gene_id")),
external_gene_name <- sapply(category, function(x) quickie(goList[[x]], var="external_gene_name")))
cat("Number of enriched GO categories (up reg):", nrow(enriched.GO_up))## Number of enriched GO categories (up reg): 20DEgenes_downs <- mydf_all %>%
filter(padj < 0.05 & log2FoldChange < -0.25) %>%
pull("mmusculus_homolog_ensembl_gene") %>% unique() %>% na.omit() %>% as.character()
genes <- as.integer(backgroundGenes_mm %in% DEgenes_downs)
names(genes) <- (backgroundGenes_mm)
pwf=nullp(genes, "mm9", "ensGene", plot.fit = FALSE) #obtain a weighting for each gene, depending on its length
GO.wall=goseq(pwf, "mm9", "ensGene")
ego <- GO.wall %>% mutate(padj = p.adjust(over_represented_pvalue, method="BH")) %>% filter(padj < 0.05)
goList <- getGeneLists(pwf, ego$category)
enriched.GO_down <- ego %>%
mutate(
mmusculus_homolog_ensembl_gene = sapply(category, function(x) paste0(goList[[x]], collapse = ",")),
ensembl_gene_id <- sapply(category, function(x) quickie(goList[[x]], var="ensembl_gene_id")),
external_gene_name <- sapply(category, function(x) quickie(goList[[x]], var="external_gene_name")))
cat("Number of enriched GO categories (down reg):", nrow(enriched.GO_down))## Number of enriched GO categories (down reg): 25tmp <- full_join(x=enriched.GO_down, y=enriched.GO_up, by=c("category", "term"))
tmp <- tmp %>% arrange(log(padj.x), na.last = TRUE)
#tmp$category <- as.factor(tmp$category)
tmp$term <- factor(tmp$term, levels=rev(unique(as.character(tmp$term)) ))
ggplot(tmp, aes(x=term)) +
geom_col(aes(y=-log(padj.y), fill="up-regulated")) +
geom_col(aes(y=log(padj.x), fill="down-regulated")) +
scale_fill_manual(values=c("orange2", "cornflowerblue"), name = "DEX list") +
coord_flip() +
labs(x="Pathway", y="log(padj)", title="GO enrichment for OXTR-/-\nby fold change direction") +
theme_minimal()
ego_up <- amanda_enrichRobject(DEgenes_ups, backgroundGenes_mm, enriched.GO_up[enriched.GO_up$numInCat < 1000, ])
ego_down <- amanda_enrichRobject(DEgenes_downs, backgroundGenes_mm, enriched.GO_down[enriched.GO_down$numInCat < 1000, ])#https://github.com/YuLab-SMU/enrichplot/blob/devel/R/treeplot.R
n = 4
mycol= hue_pal()(n)
p1 <- treeplot(ego_up, color="p.adjust", showCategory = 65,
cluster.params = list(color=mycol, n=n)) +
scale_fill_manual(values=rep(c("white"), n)) +
scale_colour_continuous(low="cornflowerblue", high="red", name = "adjp",
guide = guide_colorbar(reverse = TRUE)) #+ theme(legend.position = "bottom")
p1$layers[[3]]$aes_params$size <- 3 # clusters
p1$layers[[7]]$aes_params$size <- 3 #tree labels
p2 <- treeplot(ego_down, color="p.adjust", showCategory = 65,
cluster.params = list(color=mycol, n=n)) +
scale_fill_manual(values=rep(c("white"), n)) +
scale_colour_continuous(low="cornflowerblue", high="red", name = "adjp",
guide = guide_colorbar(reverse = TRUE)) #+ theme(legend.position = "bottom")
p2$layers[[3]]$aes_params$size <- 3 # clusters
p2$layers[[7]]$aes_params$size <- 3 #tree labelsgrid.arrange(p1 + ggtitle("up-regulated genes")+ theme(legend.position = "none"),
p2 + ggtitle("down-regulated genes"), ncol=2)
GO by sex-specific lists.
#run GO on sex-specific lists
DEgenes_male <- vole_annotation %>%
filter(ensembl_gene_id %in% x$Male) %>%
pull("mmusculus_homolog_ensembl_gene") %>% unique() %>% na.omit() %>% as.character()
genes <- as.integer(backgroundGenes_mm %in% DEgenes_male)
names(genes) <- (backgroundGenes_mm)
pwf=nullp(genes, "mm9", "ensGene", plot.fit = FALSE) #obtain a weighting for each gene, depending on its length
GO.wall=goseq(pwf, "mm9", "ensGene")
ego <- GO.wall %>% mutate(padj = p.adjust(over_represented_pvalue, method="BH")) %>% filter(padj < 0.05)
goList <- getGeneLists(pwf, ego$category)
enriched.GO_male <- ego %>%
mutate(
mmusculus_homolog_ensembl_gene = sapply(category, function(x) paste0(goList[[x]], collapse = ",")),
ensembl_gene_id <- sapply(category, function(x) quickie(goList[[x]], var="ensembl_gene_id")),
external_gene_name <- sapply(category, function(x) quickie(goList[[x]], var="external_gene_name")))
cat("Number of enriched GO categories (male):", nrow(enriched.GO_male))## Number of enriched GO categories (male): 12#run GO on sex-specific lists
DEgenes_female <- vole_annotation %>%
filter(ensembl_gene_id %in% x$Female) %>%
pull("mmusculus_homolog_ensembl_gene") %>% unique() %>% na.omit() %>% as.character()
genes <- as.integer(backgroundGenes_mm %in% DEgenes_female)
names(genes) <- (backgroundGenes_mm)
pwf=nullp(genes, "mm9", "ensGene", plot.fit = FALSE) #obtain a weighting for each gene, depending on its length
GO.wall=goseq(pwf, "mm9", "ensGene")
ego <- GO.wall %>% mutate(padj = p.adjust(over_represented_pvalue, method="BH")) %>% filter(padj < 0.05)
goList <- getGeneLists(pwf, ego$category)
enriched.GO_female <- ego %>%
mutate(
mmusculus_homolog_ensembl_gene = sapply(category, function(x) paste0(goList[[x]], collapse = ",")),
ensembl_gene_id <- sapply(category, function(x) quickie(goList[[x]], var="ensembl_gene_id")),
external_gene_name <- sapply(category, function(x) quickie(goList[[x]], var="external_gene_name")))
cat("Number of enriched GO categories (female):", nrow(enriched.GO_female))## Number of enriched GO categories (female): 34ego_female <- amanda_enrichRobject(DEgenes_female, backgroundGenes_mm, enriched.GO_female[enriched.GO_female$numInCat < 1000, ])
ego_male <- amanda_enrichRobject(DEgenes_male, backgroundGenes_mm, enriched.GO_male[enriched.GO_male$numInCat < 1000, ])n = 4
mycol= hue_pal()(n)
p1 <- treeplot(ego_female, color="p.adjust", showCategory = 65,
cluster.params = list(color=mycol, n=n)) +
scale_fill_manual(values=rep(c("white"), n)) +
scale_colour_continuous(low="cornflowerblue", high="red", name = "adjp",
guide = guide_colorbar(reverse = TRUE)) #+ theme(legend.position = "bottom")
p1$layers[[3]]$aes_params$size <- 3 # clusters
p1$layers[[7]]$aes_params$size <- 3 #tree labels
p2 <- treeplot(ego_male, color="p.adjust", showCategory = 65,
cluster.params = list(color=mycol, n=n)) +
scale_fill_manual(values=rep(c("white"), n)) +
scale_colour_continuous(low="cornflowerblue", high="red", name = "adjp",
guide = guide_colorbar(reverse = TRUE)) #+ theme(legend.position = "bottom")
p2$layers[[3]]$aes_params$size <- 3 # clusters
p2$layers[[7]]$aes_params$size <- 3 #tree labelsgrid.arrange(p1 + ggtitle("Female GO")+ theme(legend.position = "none"),
p2 + ggtitle("Male GO"), ncol=2)
- Here all expressed genes with mouse ortholog are used as the
background.
- Showing the full list like this just so everyone can get the full
picture.
- Obviously for the publication we’ll present a paired down
figure.
- We can see that the ‘joint’ list does have a fairly different profile from both female and in particular male lists.
tmp <- full_join(enriched.GO, full_join(x=enriched.GO_male, y=enriched.GO_female, by=c("category", "term")), by=c("category", "term"))
tmp <- tmp %>% arrange(log(padj), na.last = TRUE)
#tmp$category <- as.factor(tmp$category)
tmp$term <- factor(tmp$term, levels=rev(unique(as.character(tmp$term)) ))
ggplot(tmp, aes(x=term)) +
geom_col(aes(y=log(padj), fill="joint")) +
geom_col(aes(y=-log(padj.y), fill="female")) +
geom_col(aes(y=-log(padj.x), fill="male")) +
scale_fill_manual(values=c("salmon", "darkgrey", "cornflowerblue"), name = "DEX list") +
coord_flip() +
labs(x="Pathway", y="log(padj)", title="GO enrichment for OXTR-/- ") +
theme_minimal()
We can easily see that the “joint” list and female list are fairly similar, while the male-specific lists is slightly different.
write.csv(enriched.GO, file=paste0(output_dir, "Genotype_GO.csv"))Enrichment: Wikipathways
#this code works but for some reason this function broke. I imagine a WP path updated and now its broke. come back and check later.
x_entrez = list(
"Joint" = genotype_df %>% filter(padj_joint < 0.05, abs(log2FC_joint) > 0.25) %>%
pull(mmusculus_entrezgene_id) %>% na.omit() %>% unique(),
"Male" = genotype_df %>% filter(padj_M < 0.05, abs(log2FC_M) > 0.25) %>%
pull(mmusculus_entrezgene_id) %>% na.omit() %>% unique() %>% as.character(),
"Female" = genotype_df %>% filter(padj_F < 0.05, abs(log2FC_F) > 0.25) %>%
pull(mmusculus_entrezgene_id) %>% na.omit() %>% unique() %>% as.character()
)
backgroundGenes_mm = vole_annotation %>%
filter(ensembl_gene_id %in% rownames(cts)) %>%
pull(mmusculus_entrezgene_id) %>% unique() %>% na.omit() %>% as.vector()
wikiList_joint <- enrichWP(gene=x_entrez$Joint,
organism = "Mus musculus",
universe = backgroundGenes_mm,
)
p1 <- dotplot(wikiList_joint, showCategory=30) + ggtitle("WikiPathways:Joint")
wikiList_F <- enrichWP(gene=x_entrez$Female,
organism = "Mus musculus",
universe = backgroundGenes_mm,
)
p2 <- dotplot(wikiList_F, showCategory=30) + ggtitle("WikiPathways:Female")
wikiList_M <- enrichWP(gene=x_entrez$Male,
organism = "Mus musculus",
universe = backgroundGenes_mm,
)
p3 <- dotplot(wikiList_M, showCategory=30) + ggtitle("WikiPathways:Male")grid.arrange(p1, p2, p3, ncol=3)p2 = p1 + ggtitle("WikiPathways over-representation") + xlab("Gene Ratio") # (DE genes in cat/ total number of DE genes in WikiPathway collection)")Over-representation
Should we use mouse/human and gene symbol/entrez ID?
In sum, mouse ensembl or symbol is the best. Followed by pretty much a wash between mouse entrez/human ensembl/human symbol
cat("Vole Ensembl:", length(unique(vole_annotation$ensembl_gene_id)))## Vole Ensembl: 23038cat("Vole Entrez:", length(unique(vole_annotation$entrezgene_id)))## Vole Entrez: 16038cat("Vole Symbol:", length(unique(vole_annotation$external_gene_name)))## Vole Symbol: 15866cat("Mouse Ensembl:", length(unique(vole_annotation$mmusculus_homolog_ensembl_gene)))## Mouse Ensembl: 18464cat("Mouse Entrez:", length(unique(vole_annotation$mmusculus_entrezgene_id)))## Mouse Entrez: 17746cat("Mouse Symbol:", length(unique(vole_annotation$mmusculus_homolog_associated_gene_name)))## Mouse Symbol: 18452cat("Human Ensembl:", length(unique(vole_annotation$hsapiens_homolog_ensembl_gene)))## Human Ensembl: 17470cat("Human Entrez:", length(unique(vole_annotation$hsapiens_entrezgene_id)))## Human Entrez: 16792cat("Human Symbol:", length(unique(vole_annotation$hsapiens_homolog_associated_gene_name)))## Human Symbol: 17312Categorical: ASD & NDD Associated Gene Lists
- Note: using all expressed vole genes with a human ortholog as background.
asd = read_excel(paste0(data_dir,"gsea/Satterstrom_2020_table_S2.xlsx"), sheet=3)
ndd = read_excel(paste0(data_dir,"gsea/Kaplanis_2020_table_S2.xlsx"), sheet=1)
epi = read_excel(paste0(data_dir,"gsea/Epileptic encephalopathy_mmc2.xlsx"), sheet=1)
scz = read_excel(paste0(data_dir,"gsea/SCZ_41586_2014_BFnature12929_MOESM39_ESM.xlsx"), sheet=1)
genelist <- c(list("ASD" = asd %>%
filter(stringr::str_detect(gene, '^[[:upper:][:digit:]]+$')) %>%
pull(gene)
),
list("NDD" = ndd %>%
filter(significant == TRUE) %>%
pull(symbol)
),
list("EPI" = na.omit(epi$Gene)),
list("SCZ" = scz$Genes)
)length(genelist$ASD)## [1] 102length(genelist$NDD)## [1] 285length(genelist$SCZ)## [1] 640length(genelist$EPI)## [1] 429There are some gene symbol alias differences. Fixing the ones I can find and printing those that are not represented in the vole annotation.
tofix_df = data.frame(old_names = c("SUV420H1", "SRPR",
"COL4A3BP", "HIST1H1E", "KMT2B (MLL4)", "C6orf222", "SELRC1","FAM134A", "TCTE3", "SGK223", "C4orf37",
"KIAA0913", "DDX58", "C1orf123", "HIST1H2BD", "GPR128", "GPR98", "CHD2 ^", "FAM116B",
"C17orf53", "C16orf62", "KIAA1324L", "FAM21C", "WHSC1L1", "FAM63B", "MLL", "FAM102A", "UHRF1BP1L",
"MLL2", "CPAMD8", "PNMAL1", "RARS",
"YARS", "LPHN2", "GBA", "DARC", "CCBP2", "KIAA2018", "HIST1H2BE", "HIST1H3G", "HIST1H4I",
"AKD1", "KIAA1244", "YAE1D1", "ACN9", "C7orf60", "MLL3", "FAM160B2", "KIAA1429", "C9orf114", "KIAA1462",
"TMEM180", "FAM160B1", "PCNXL3", "WARS", "SOLH", "BZRAP1", "SLC9A3R1", "PEG3,ZIM2", "GTPBP5"),
new_names = c("KMT5B", "SRPRA",
"CERT1", "H1-4", "KMT2B", "BNIP5", "COA7", "RETREG2", "DYNLT2", "PRAG1", "STPG2", "ZSWIM8", "RIGI",
"CZIB", "H2BC5", "ADGRG7", "ADGRV1", "CHD2", "DENND6B", "HROB", "VPS35L", "ELAPOR2", "WASHC2C",
"NSD3", "MINDY2", "KMT2A", "EEIG1", "BLTP3B", "KMT2D", "VIP", "PNMA8A", "RARS1",
"YARS1","ADGRL2", "GBA1", "ACKR1", "ACKR2", "USF1", "H2BC4", "H3C8", "H4C9", "AK9",
"ARFGEF3", "YAE1", "SDHAF3", "BMT2", "KMT2C", "FHIP2B", "VIRMA", "SPOUT1", "JCAD", "MFSD13A",
"FHIP2A", "PCNX3", "WARS1", "CAPN15", "TSPOAP1", "NHERF1", "PEG3", "MTG2"))
for (e in names(genelist)){
print(e); print("missing gene symbol:")
replace = genelist[[e]][genelist[[e]] %in% tofix_df$old_names]
genelist[[e]] = c(tofix_df[tofix_df$old_names %in% replace, "new_names"], genelist[[e]][genelist[[e]] %ni% replace])
print(setdiff(genelist[[e]], unique(vole_annotation$hsapiens_homolog_associated_gene_name)))
}## [1] "ASD"
## [1] "missing gene symbol:"
## character(0)
## [1] "NDD"
## [1] "missing gene symbol:"
## [1] "ALG13" "H3F3A" "HNRNPK" "POU3F3" "SOX11"
## [1] "EPI"
## [1] "missing gene symbol:"
## [1] "TAS2R4" "CXXC11" "ZNF572" "LEKR1" "FAM86C1" "NLRP8"
## [7] "RAET1L" "NLRP11" "ZNF839" "OR10S1" "ALG13" "B3GNT4"
## [13] "AKR1C4" "ADAM21" "KLHL11" "LCE1A" "ALMS1" "GRAMD2"
## [19] "FASN" "PCDHB13" "HIST2H2BE" "GLB1L3" "FLG" "KRTAP1-3"
## [25] "SLCO1B7"
## [1] "SCZ"
## [1] "missing gene symbol:"
## [1] "H4C9" "RPL5" "FCGR3B"
## [4] "ALMS1" "PSAPL1" "OR11A1"
## [7] "NUPL2" "POM121C" "AKAP9"
## [10] "ATP5J2-PTCD1,PTCD1" "TAS2R3" "SSPO"
## [13] "EPPK1" "HAUS6" "CTSL1"
## [16] "EXD3" "IGSF22" "SPDYC"
## [19] "GDPD5" "CLNS1A" "CD163L1"
## [22] "SLCO1B7" "C12orf74" "DEPDC4"
## [25] "PSMB11" "TINF2" "ACSM2B"
## [28] "ALOX15" "ZNF77" "EMR1"
## [31] "KXD1" "ZNF607" "ZNF551"
## [34] "SLMO2" "C20orf197" "KRTAP10-3"
## [37] "CCT8L2" "APOL5" "ARSE"
## [40] "MUM1L1"amanda_build_cont <- function(tmp, genelist, FCcutoff, Pcutoff=0.05){
tmp <- tmp %>% filter(hsapiens_homolog_associated_gene_name != "")
sig <- tmp %>% filter(padj <= Pcutoff & abs(log2FoldChange) > FCcutoff) %>% pull(ensembl_gene_id)
mycontigency <- data.frame(
row.names=c("Differentially_expressed", "Not_Differentially_Expressed"),
inlist=c(
tmp %>% filter(ensembl_gene_id %in% sig & hsapiens_homolog_associated_gene_name %in% genelist) %>% nrow(),
tmp %>% filter(ensembl_gene_id %ni% sig & hsapiens_homolog_associated_gene_name %in% genelist) %>% nrow()),
notinlist=c(
tmp %>% filter(ensembl_gene_id %in% sig & hsapiens_homolog_associated_gene_name %ni% genelist) %>% nrow(),
tmp %>% filter(ensembl_gene_id %ni% sig & hsapiens_homolog_associated_gene_name %ni% genelist) %>% nrow())
)
return(mycontigency)
}OverRep_df <- data.frame(matrix(nrow = 0, ncol = 5))
for (i in names(genelist)){
for (j in c(0, 0.25)) {
for (k in c(0.05, 0.01)){
mycontigency <- amanda_build_cont(mydf_all, genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Joint", i, j, k, "both", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_all %>% filter(log2FoldChange >=0), genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Joint", i, j, k, "up", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_all %>% filter(log2FoldChange <0), genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Joint", i, j, k, "down", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_F, genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Female", i, j, k, "both", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_F %>% filter(log2FoldChange >=0), genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Female", i, j, k, "up", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_F %>% filter(log2FoldChange <0), genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Female", i, j, k, "down", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_M, genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Male", i, j, k, "both", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_M %>% filter(log2FoldChange >=0), genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Male", i, j, k, "up", chisq.test(mycontigency)$p.value))
mycontigency <- amanda_build_cont(mydf_M %>% filter(log2FoldChange <0), genelist[[i]], FCcutoff=j, Pcutoff=k)
OverRep_df <- rbind(OverRep_df, c("Male", i, j, k, "down", chisq.test(mycontigency)$p.value))
}
}
}
colnames(OverRep_df) <- c("DEXlist", "EnrichmentList", "FCcut", "Pcut", "FC_direction", "ChiSq_pval")
OverRep_df$ChiSq_pval <- as.numeric(OverRep_df$ChiSq_pval)
OverRep_df$FC_direction <- as.factor(OverRep_df$FC_direction)
OverRep_df$FC_direction <- factor(OverRep_df$FC_direction, levels=c("both", "up", "down"))
OverRep_df$DEXlist <- as.factor(OverRep_df$DEXlist)
OverRep_df$DEXlist <- factor(OverRep_df$DEXlist, levels=c("Joint", "Female", "Male"))tmp <- OverRep_df %>%
filter(Pcut == 0.01 & FCcut == 0) %>%
filter(FC_direction != "both") %>%
mutate(padj = p.adjust(ChiSq_pval, method = "BH"))
g1 <- ggplot(tmp, aes(x = FC_direction, y = EnrichmentList, fill = log(padj))) +
geom_tile(size=0.1, color='grey', show.legend = T, lwd = 1.5, linetype = 1) +
scale_fill_gradient2(low="#CD2836", high="#6A90CA", name="log(Adjusted ChiSq P-value)") +
geom_text(aes(label = ifelse(padj <= 0.05, "*", "")), color = "black", size = 8) +
coord_equal() +
facet_wrap(~DEXlist) +
xlab("") + ylab("") + ggtitle("Over-representation of Disease associated genes (padj < 0.01, abs(FC) > 0)")+
theme_minimal(base_size=7) +
theme(text=element_text(size=14, face = "bold"),
#strip.text.x = element_text(size = 16),
plot.title = element_text(size=12, hjust = 0.5),
axis.ticks=element_blank(),
panel.border=element_blank(),
panel.grid.major = element_blank(),
panel.grid.minor = element_blank(),
panel.background = element_blank(),
axis.text.x=element_text(size=14, angle=320, hjust = 0, colour="grey50"))## Warning: Using `size` aesthetic for lines was deprecated in ggplot2 3.4.0.
## ℹ Please use `linewidth` instead.
## This warning is displayed once every 8 hours.
## Call `lifecycle::last_lifecycle_warnings()` to see where this warning was
## generated.g1
ggsave(plot=g1, file=paste0(output_dir, "figures/Fig6F_Disease.svg"), width=10, height=10)scRNAseq Enrichments
- Manuscript to compare to: https://www.nature.com/articles/s41586-020-2266-0
- Source seurat object from https://cells.ucsc.edu/mouse-hypothalamus-dev/
knitr::knit_exit()